Compile Data Set for Download or QSAR
Found 69 with Last Name = 'patel' and Initial = 'br'
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6745(1,7-Annulated indolocarbazole deriv. 13Ab | 7-fluo...)copy SMILEScopy InChI
Affinity DataIC50: 2nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6756(1,7-Annulated indolocarbazole deriv. 16-b | 7-fluo...)copy SMILEScopy InChI
Affinity DataIC50: 8nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6747(1,7-Annulated indolocarbazole deriv. 13Bc | 7-brom...)copy SMILEScopy InChI
Affinity DataIC50: 10nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6749(1,7-Annulated indolocarbazole deriv. 13Be | 24-(hy...)copy SMILEScopy InChI
Affinity DataIC50: 15nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6742(1,7-Annulated indolocarbazole deriv. 13Aa | 25-(hy...)copy SMILEScopy InChI
Affinity DataIC50: 18nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6746(1,7-Annulated indolocarbazole deriv. 13Bb | 7-fluo...)copy SMILEScopy InChI
Affinity DataIC50: 22nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6748(1,7-Annulated indolocarbazole deriv. 13Bd | 24-(hy...)copy SMILEScopy InChI
Affinity DataIC50: 23nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6744(1,7-Annulated indolocarbazole deriv. 13Ca | 23-(hy...)copy SMILEScopy InChI
Affinity DataIC50: 31nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6736(1,7-Annulated indolocarbazole deriv. 16c | 7-(pyrr...)copy SMILEScopy InChI
Affinity DataIC50: 50nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6755(1,7-Annulated indolocarbazole deriv. 16-a | 24-(ch...)copy SMILEScopy InChI
Affinity DataIC50: 64nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6740(1,7-Annulated indolocarbazole deriv. 16g | 7-(pipe...)copy SMILEScopy InChI
Affinity DataIC50: 65nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6743(1,7-Annulated indolocarbazole deriv. 13Ba | 24-(hy...)copy SMILEScopy InChI
Affinity DataIC50: 71nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6752(1,7-Annulated indolocarbazole deriv. 13Bf | 25-(hy...)copy SMILEScopy InChI
Affinity DataIC50: 72nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6738(1,7-Annulated indolocarbazole deriv. 16e | 7-(morp...)copy SMILEScopy InChI
Affinity DataIC50: 75nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6735(1,7-Annulated indolocarbazole deriv. 16b | 7-(azet...)copy SMILEScopy InChI
Affinity DataIC50: 75nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6741(1,7-Annulated indolocarbazole deriv. 16h | 7-(1,4-...)copy SMILEScopy InChI
Affinity DataIC50: 79nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6745(1,7-Annulated indolocarbazole deriv. 13Ab | 7-fluo...)copy SMILEScopy InChI
Affinity DataIC50: 79nMT: 2°CAssay Description:In vitro assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP. 33P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6754(1,7-Annulated indolocarbazole deriv. 13Bg | 24-(hy...)copy SMILEScopy InChI
Affinity DataIC50: 84nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6737(1,7-Annulated indolocarbazole deriv. 16d | 7-(pipe...)copy SMILEScopy InChI
Affinity DataIC50: 87nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6729(1,7-Annulated indolocarbazole deriv. 6l | 7-bromo-...)copy SMILEScopy InChI
Affinity DataIC50: 90nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6739(1,7-Annulated indolocarbazole deriv. 16f | 7-(thio...)copy SMILEScopy InChI
Affinity DataIC50: 90nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6720(1,4,14-triazaheptacyclo[16.8.1.0^{2,17}.0^{3,11}.0...)copy SMILEScopy InChI
Affinity DataIC50: 94nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6728(1,7-Annulated indolocarbazole deriv. 6k | 7-chloro...)copy SMILEScopy InChI
Affinity DataIC50: 110nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6719(1,4,14-triazaheptacyclo[16.7.1.0^{2,17}.0^{3,11}.0...)copy SMILEScopy InChI
Affinity DataIC50: 110nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6721(1,4,14-triazaheptacyclo[16.9.1.0^{2,17}.0^{3,11}.0...)copy SMILEScopy InChI
Affinity DataIC50: 120nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6750(1,7-Annulated indolocarbazole deriv. 13Da | 25-(hy...)copy SMILEScopy InChI
Affinity DataIC50: 126nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6746(1,7-Annulated indolocarbazole deriv. 13Bb | 7-fluo...)copy SMILEScopy InChI
Affinity DataIC50: 141nMT: 2°CAssay Description:In vitro assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP. 33P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6732(1,7-Annulated indolocarbazole deriv. 6o | 7-(pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 160nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6734(1,7-Annulated indolocarbazole deriv. 16a | 7-(amin...)copy SMILEScopy InChI
Affinity DataIC50: 170nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6751(1,7-Annulated indolocarbazole deriv. 13Af | 26-(hy...)copy SMILEScopy InChI
Affinity DataIC50: 175nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6753(1,7-Annulated indolocarbazole deriv. 13Cf | 24-(hy...)copy SMILEScopy InChI
Affinity DataIC50: 210nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6743(1,7-Annulated indolocarbazole deriv. 13Ba | 24-(hy...)copy SMILEScopy InChI
Affinity DataIC50: 217nMT: 2°CAssay Description:In vitro assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP. 33P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6742(1,7-Annulated indolocarbazole deriv. 13Aa | 25-(hy...)copy SMILEScopy InChI
Affinity DataIC50: 219nMT: 2°CAssay Description:In vitro assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP. 33P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6718(1,4,14-triazaheptacyclo[16.6.1.0^{2,17}.0^{3,11}.0...)copy SMILEScopy InChI
Affinity DataIC50: 240nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6749(1,7-Annulated indolocarbazole deriv. 13Be | 24-(hy...)copy SMILEScopy InChI
Affinity DataIC50: 284nMT: 2°CAssay Description:In vitro assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP. 33P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6730(1,7-Annulated indolocarbazole deriv. 6m | 7-(trifl...)copy SMILEScopy InChI
Affinity DataIC50: 290nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Lilly Research Laboratories

LigandPNGBDBM6756(1,7-Annulated indolocarbazole deriv. 16-b | 7-fluo...)copy SMILEScopy InChI
Affinity DataIC50: 383nMT: 2°CAssay Description:In vitro assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP. 33P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6727(1,7-Annulated indolocarbazole deriv. 6j | 7-fluoro...)copy SMILEScopy InChI
Affinity DataIC50: 420nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6733(1,7-Annulated indolocarbazole deriv. 6p | 7-(pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 590nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6754(1,7-Annulated indolocarbazole deriv. 13Bg | 24-(hy...)copy SMILEScopy InChI
Affinity DataIC50: 650nMT: 2°CAssay Description:In vitro assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP. 33P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6758(1,4-dimethyl 2-[({7-fluoro-13,15-dioxo-1,4,14-tria...)copy SMILEScopy InChI
Affinity DataIC50: 671nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Lilly Research Laboratories

LigandPNGBDBM6742(1,7-Annulated indolocarbazole deriv. 13Aa | 25-(hy...)copy SMILEScopy InChI
Affinity DataIC50: 858nMT: 2°CAssay Description:In vitro assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP. 33P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6757(1,7-Annulated indolocarbazole deriv. 16-c | 24-[(d...)copy SMILEScopy InChI
Affinity DataIC50: 898nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6729(1,7-Annulated indolocarbazole deriv. 6l | 7-bromo-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6720(1,4,14-triazaheptacyclo[16.8.1.0^{2,17}.0^{3,11}.0...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6719(1,4,14-triazaheptacyclo[16.7.1.0^{2,17}.0^{3,11}.0...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52MTTPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Lilly Research Laboratories

LigandPNGBDBM6752(1,7-Annulated indolocarbazole deriv. 13Bf | 25-(hy...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMT: 2°CAssay Description:In vitro assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP. 33P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Lilly Research Laboratories

LigandPNGBDBM6748(1,7-Annulated indolocarbazole deriv. 13Bd | 24-(hy...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMT: 2°CAssay Description:In vitro assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP. 33P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Lilly Research Laboratories

LigandPNGBDBM6746(1,7-Annulated indolocarbazole deriv. 13Bb | 7-fluo...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMT: 2°CAssay Description:In vitro assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP. 33P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Lilly Research Laboratories

LigandPNGBDBM6745(1,7-Annulated indolocarbazole deriv. 13Ab | 7-fluo...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMT: 2°CAssay Description:In vitro assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP. 33P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
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