Compile Data Set for Download or QSAR
Found 42 with Last Name = 'willis' and Initial = 'bs'
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50484231(CHEMBL1822068)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of full length human B-Raf V600E mutant expressed in baculovirus infected insect cells assessed as [gamma-33P]incorporation into MEK after...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134VMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50484261(CHEMBL1822246)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMAssay Description:Inhibition of full length human B-Raf V600E mutant expressed in baculovirus infected insect cells assessed as [gamma-33P]incorporation into MEK after...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134VMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50484223(CHEMBL1822241)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of full length human B-Raf V600E mutant expressed in baculovirus infected insect cells assessed as [gamma-33P]incorporation into MEK after...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134VMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50484234(CHEMBL1822067)copy SMILEScopy InChI
Affinity DataIC50: 4.80nMAssay Description:Inhibition of full length human B-Raf V600E mutant expressed in baculovirus infected insect cells assessed as [gamma-33P]incorporation into MEK after...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134VMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50484698(CHEMBL1945165)copy SMILEScopy InChI
Affinity DataIC50: 6.30nMAssay Description:Inhibition of full length human B-Raf V600E mutant expressed in baculovirus infected insect cells assessed as [gamma-33P]incorporation into MEK after...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134VMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50484703(CHEMBL1945164)copy SMILEScopy InChI
Affinity DataIC50: 8.20nMAssay Description:Inhibition of full length human B-Raf V600E mutant expressed in baculovirus infected insect cells assessed as [gamma-33P]incorporation into MEK after...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134VMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50484246(CHEMBL1822243)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of full length human B-Raf V600E mutant expressed in baculovirus infected insect cells assessed as [gamma-33P]incorporation into MEK after...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134VMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50484247(CHEMBL1822110)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of full length human B-Raf V600E mutant expressed in baculovirus infected insect cells assessed as [gamma-33P]incorporation into MEK after...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134VMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50484234(CHEMBL1822067)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human MALME-3M cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134VMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50484231(CHEMBL1822068)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human MALME-3M cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134VMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50396483(PLX-4032 | RG 7204 | Ro 5185426 | US10570155, Vemu...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of full length human B-Raf V600E mutant expressed in baculovirus infected insect cells assessed as [gamma-33P]incorporation into MEK after...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50484239(CHEMBL1822078)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of full length human B-Raf V600E mutant expressed in baculovirus infected insect cells assessed as [gamma-33P]incorporation into MEK after...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134VMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50484261(CHEMBL1822246)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human MALME-3M cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134VMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50484703(CHEMBL1945164)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human MALME-3M cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134VMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50484223(CHEMBL1822241)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human MALME-3M cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134VMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50484698(CHEMBL1945165)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human MALME-3M cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134VMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50396483(PLX-4032 | RG 7204 | Ro 5185426 | US10570155, Vemu...)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human MALME-3M cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50484699(CHEMBL1945163)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Inhibition of full length human B-Raf V600E mutant expressed in baculovirus infected insect cells assessed as [gamma-33P]incorporation into MEK after...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134VMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50484247(CHEMBL1822110)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human MALME-3M cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134VMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50484246(CHEMBL1822243)copy SMILEScopy InChI
Affinity DataIC50: 86nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human MALME-3M cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134VMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50484239(CHEMBL1822078)copy SMILEScopy InChI
Affinity DataIC50: 94nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human MALME-3M cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134VMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50484702(CHEMBL1945020)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of full length human B-Raf V600E mutant expressed in baculovirus infected insect cells assessed as [gamma-33P]incorporation into MEK after...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50484234(CHEMBL1822067)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human A375 cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134VMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50396483(PLX-4032 | RG 7204 | Ro 5185426 | US10570155, Vemu...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human A375 cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50484261(CHEMBL1822246)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human A375 cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134VMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50484231(CHEMBL1822068)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human A375 cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134VMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50484223(CHEMBL1822241)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human A375 cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134VMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50484239(CHEMBL1822078)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human A375 cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134VMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50484702(CHEMBL1945020)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human MALME-3M cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50484247(CHEMBL1822110)copy SMILEScopy InChI
Affinity DataIC50: 430nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human A375 cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134VMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50484698(CHEMBL1945165)copy SMILEScopy InChI
Affinity DataIC50: 560nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human A375 cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134VMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50484703(CHEMBL1945164)copy SMILEScopy InChI
Affinity DataIC50: 650nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human A375 cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134VMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50484246(CHEMBL1822243)copy SMILEScopy InChI
Affinity DataIC50: 830nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human A375 cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134VMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50484700(CHEMBL1945019)copy SMILEScopy InChI
Affinity DataIC50: 920nMAssay Description:Inhibition of full length human B-Raf V600E mutant expressed in baculovirus infected insect cells assessed as [gamma-33P]incorporation into MEK after...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134VMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50484702(CHEMBL1945020)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human A375 cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50484699(CHEMBL1945163)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human MALME-3M cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134VMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50484700(CHEMBL1945019)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human MALME-3M cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134VMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50484700(CHEMBL1945019)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human A375 cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134VMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50484701(CHEMBL1945018)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human A375 cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134VMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50484699(CHEMBL1945163)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human A375 cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134VMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50484701(CHEMBL1945018)copy SMILEScopy InChI
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of full length human B-Raf V600E mutant expressed in baculovirus infected insect cells assessed as [gamma-33P]incorporation into MEK after...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134VMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50484701(CHEMBL1945018)copy SMILEScopy InChI
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human MALME-3M cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134VMPubMed