Compile Data Set for Download or QSAR
Found 118 with Last Name = 'donovan' and Initial = 'bt'
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306154((2S)-1-(1H-indol-3-yl)-3-(5-(3-methyl-1H-pyrazolo[...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human AKT1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CXXPubMed
TargetRAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306165(3-((2S)-2-amino-3-(2-amino-5-(3-methyl-1H-pyrazolo...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human AKT3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CXXPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306156(3-((S)-2-amino-3-(1H-indol-3-yl)propoxy)-5-(3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human AKT1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CXXPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306165(3-((2S)-2-amino-3-(2-amino-5-(3-methyl-1H-pyrazolo...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human AKT1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CXXPubMed
TargetRAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306155(3-((S)-2-amino-3-(1H-indol-3-yl)propoxy)-5-(3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human AKT3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CXXPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306158(3-((S)-2-amino-3-(1H-indol-3-yl)propoxy)-5-(3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human AKT1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CXXPubMed
TargetRAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306164(3-((2S)-2-amino-3-(2-amino-5-(3-methyl-1H-pyrazolo...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human AKT3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CXXPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306164(3-((2S)-2-amino-3-(2-amino-5-(3-methyl-1H-pyrazolo...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human AKT1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CXXPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306157(3-((S)-2-amino-3-(1H-indol-3-yl)propoxy)-5-(3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human AKT1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CXXPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306163(3-((S)-2-amino-3-(2-chloro-1H-indol-3-yl)propoxy)-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human AKT1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CXXPubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50467984(CHEMBL4293287)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of full length His/flag-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescently labeled substrate inc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8VJVPubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50467989(CHEMBL4282034)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of full length His/flag-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescently labeled substrate inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8VJVPubMed
TargetRAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306157(3-((S)-2-amino-3-(1H-indol-3-yl)propoxy)-5-(3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human AKT3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CXXPubMed
TargetRAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306163(3-((S)-2-amino-3-(2-chloro-1H-indol-3-yl)propoxy)-...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human AKT3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CXXPubMed
TargetRAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306156(3-((S)-2-amino-3-(1H-indol-3-yl)propoxy)-5-(3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human AKT3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CXXPubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50467980(CHEMBL4292228)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of full length His/flag-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescently labeled substrate inc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8VJVPubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50467979(CHEMBL4285837)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of full length His/flag-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescently labeled substrate inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8VJVPubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50467986(CHEMBL4289904)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of full length His/flag-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescently labeled substrate inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8VJVPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306160((S)-1-(6-(furan-3-yl)-2-methyl-5-(3-methyl-1H-pyra...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human AKT1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CXXPubMed
TargetRAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306158(3-((S)-2-amino-3-(1H-indol-3-yl)propoxy)-5-(3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human AKT3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CXXPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306155(3-((S)-2-amino-3-(1H-indol-3-yl)propoxy)-5-(3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human AKT1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CXXPubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50184765(CHEMBL3823499)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of full length His/flag-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescently labeled substrate inc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8VJVPubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50467980(CHEMBL4292228)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of RIPK2 in human whole blood assessed as reduction in MDP-stimulated TNFalpha levels incubated for 30 mins followed by MDP addition measu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8VJVPubMed
TargetRAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306161(3-((S)-2-amino-3-phenylpropoxy)-5-(3-methyl-1H-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human AKT3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CXXPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306161(3-((S)-2-amino-3-phenylpropoxy)-5-(3-methyl-1H-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human AKT1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CXXPubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50467982(CHEMBL4281602)copy SMILEScopy InChI
Affinity DataIC50: 6.30nMAssay Description:Inhibition of full length His/flag-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescently labeled substrate inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8VJVPubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50467988(CHEMBL4285462)copy SMILEScopy InChI
Affinity DataIC50: 6.30nMAssay Description:Inhibition of full length His/flag-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescently labeled substrate inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8VJVPubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306164(3-((2S)-2-amino-3-(2-amino-5-(3-methyl-1H-pyrazolo...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of human AKT2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CXXPubMed
TargetRAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306160((S)-1-(6-(furan-3-yl)-2-methyl-5-(3-methyl-1H-pyra...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human AKT3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CXXPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306159((S)-3-(2-amino-3-(1H-indol-3-yl)propoxy)-6-(furan-...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human AKT1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CXXPubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50467984(CHEMBL4293287)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of RIPK2 in human whole blood assessed as reduction in MDP-stimulated TNFalpha levels incubated for 30 mins followed by MDP addition measu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8VJVPubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306163(3-((S)-2-amino-3-(2-chloro-1H-indol-3-yl)propoxy)-...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of human AKT2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CXXPubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306158(3-((S)-2-amino-3-(1H-indol-3-yl)propoxy)-5-(3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human AKT2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CXXPubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Rattus norvegicus)
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50467984(CHEMBL4293287)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of RIPK2 in rat whole blood assessed as reduction in MDP-stimulated TNFalpha levels incubated for 30 mins followed by MDP addition measure...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8VJVPubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306156(3-((S)-2-amino-3-(1H-indol-3-yl)propoxy)-5-(3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of human AKT2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CXXPubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306155(3-((S)-2-amino-3-(1H-indol-3-yl)propoxy)-5-(3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of human AKT2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CXXPubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50467986(CHEMBL4289904)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of RIPK2 in human whole blood assessed as reduction in MDP-stimulated TNFalpha levels incubated for 30 mins followed by MDP addition measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8VJVPubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306165(3-((2S)-2-amino-3-(2-amino-5-(3-methyl-1H-pyrazolo...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of human AKT2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CXXPubMed
TargetRAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306159((S)-3-(2-amino-3-(1H-indol-3-yl)propoxy)-6-(furan-...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of human AKT3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CXXPubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306157(3-((S)-2-amino-3-(1H-indol-3-yl)propoxy)-5-(3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of human AKT2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CXXPubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306154((2S)-1-(1H-indol-3-yl)-3-(5-(3-methyl-1H-pyrazolo[...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of human AKT2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CXXPubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50510295(CHEMBL4443422)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of Escherichia coli his-tagged DNA gyrase supercoiling activity using pBR322 DNA in presence of ATP incubated for 1 hr by H19 dye based hi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC64HZPubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50467989(CHEMBL4282034)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of RIPK2 in human whole blood assessed as reduction in MDP-stimulated TNFalpha levels incubated for 30 mins followed by MDP addition measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8VJVPubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306160((S)-1-(6-(furan-3-yl)-2-methyl-5-(3-methyl-1H-pyra...)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of human AKT2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CXXPubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50467981(CHEMBL4278565)copy SMILEScopy InChI
Affinity DataIC50: 79nMAssay Description:Inhibition of full length His/flag-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescently labeled substrate inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8VJVPubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50467988(CHEMBL4285462)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of RIPK2 in human whole blood assessed as reduction in MDP-stimulated TNFalpha levels incubated for 30 mins followed by MDP addition measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8VJVPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306155(3-((S)-2-amino-3-(1H-indol-3-yl)propoxy)-5-(3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CXXPubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50467985(CHEMBL4283104)copy SMILEScopy InChI
Affinity DataIC50: 126nMAssay Description:Inhibition of full length His/flag-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescently labeled substrate inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8VJVPubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306161(3-((S)-2-amino-3-phenylpropoxy)-5-(3-methyl-1H-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of human AKT2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CXXPubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50467979(CHEMBL4285837)copy SMILEScopy InChI
Affinity DataIC50: 154nMAssay Description:Inhibition of RIPK2 in human whole blood assessed as reduction in MDP-stimulated TNFalpha levels incubated for 30 mins followed by MDP addition measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8VJVPubMed
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