Compile Data Set for Download or QSAR
Found 124 with Last Name = 'adcock' and Initial = 'c'
TargetProstaglandin D2 receptor 2(Mus musculus (mouse))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296848(2-(1-(3,4-difluorophenylsulfonyl)-2-methyl-1H-pyrr...)copy SMILEScopy InChI
Affinity DataKi:  28nMAssay Description:Displacement of [3H]PGD2 from mouse CRTh2 receptor expressed in K562 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296848(2-(1-(3,4-difluorophenylsulfonyl)-2-methyl-1H-pyrr...)copy SMILEScopy InChI
Affinity DataKi:  31nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296849(2-(1-(4-chloro-3-cyanophenylsulfonyl)-2-methyl-1H-...)copy SMILEScopy InChI
Affinity DataKi:  35nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296850(2-(1-(3-cyano-4-fluorophenylsulfonyl)-2-methyl-1H-...)copy SMILEScopy InChI
Affinity DataKi:  36nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296847(2-(1-(4-cyano-3-ethoxyphenylsulfonyl)-2-methyl-1H-...)copy SMILEScopy InChI
Affinity DataKi:  43nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296859(2-(2-methyl-1-(4-nitrophenylsulfonyl)-1H-pyrrolo[2...)copy SMILEScopy InChI
Affinity DataKi:  48nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296857(2-(1-(3,4-dichlorophenylsulfonyl)-2-methyl-1H-pyrr...)copy SMILEScopy InChI
Affinity DataKi:  52nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296846(2-(1-(4-fluoro-3-methoxyphenylsulfonyl)-2-methyl-1...)copy SMILEScopy InChI
Affinity DataKi:  56nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50213919(2-(4-chloro-2-cycloheptylphenoxy)acetic acid | CHE...)copy SMILEScopy InChI
Affinity DataKi:  59nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50161746((R)-3-(3-(4-fluorophenylsulfonamido)-1,2,3,4-tetra...)copy SMILEScopy InChI
Affinity DataKi:  73nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296851(2-(1-(4-chlorophenylsulfonyl)-2-methyl-1H-pyrrolo[...)copy SMILEScopy InChI
Affinity DataKi:  103nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296845(2-(1-(3-chloro-4-fluorophenylsulfonyl)-2-methyl-1H...)copy SMILEScopy InChI
Affinity DataKi:  158nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296854(2-(2-methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]py...)copy SMILEScopy InChI
Affinity DataKi:  282nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296852(2-(1-(3-chlorophenylsulfonyl)-2-methyl-1H-pyrrolo[...)copy SMILEScopy InChI
Affinity DataKi:  377nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296856(2-(2-methyl-1-tosyl-1H-pyrrolo[2,3-b]pyridin-3-yl)...)copy SMILEScopy InChI
Affinity DataKi:  619nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296858(2-(1-(4-chloro-3-(trifluoromethyl)phenylsulfonyl)-...)copy SMILEScopy InChI
Affinity DataKi:  1.17E+3nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296855(2-(1-(4-methoxyphenylsulfonyl)-2-methyl-1H-pyrrolo...)copy SMILEScopy InChI
Affinity DataKi:  2.62E+3nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296853(2-(1-(2-chlorophenylsulfonyl)-2-methyl-1H-pyrrolo[...)copy SMILEScopy InChI
Affinity DataKi:  3.22E+3nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296851(2-(1-(4-chlorophenylsulfonyl)-2-methyl-1H-pyrrolo[...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human prostaglandin D2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296851(2-(1-(4-chlorophenylsulfonyl)-2-methyl-1H-pyrrolo[...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human thromboxane A2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
KuDOS Pharmaceuticals Ltd.

LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:A FlashPlate scintillation proximity assay has been used to identify inhibitors of PARP-2. PARP-2 protein (recombinant) was bound down by a PARP-2 sp...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
KuDOS Pharmaceuticals Ltd.

LigandPNGBDBM27542(4-(3-(piperazine-1-carbonyl)benzyl)phthalazin-1(2H...)copy SMILEScopy InChI
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP014TPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
KuDOS Pharmaceuticals Ltd.

LigandPNGBDBM27545(4-[(4-fluoro-3-{[4-(pyridin-2-yl)piperazin-1-yl]ca...)copy SMILEScopy InChI
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP014TPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
KuDOS Pharmaceuticals Ltd.

LigandPNGBDBM27546(4-[(3-{[4-(pyrimidin-2-yl)piperazin-1-yl]carbonyl}...)copy SMILEScopy InChI
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP014TPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
KuDOS Pharmaceuticals Ltd.

LigandPNGBDBM27567(4-({3-[(4-cyclopentanecarbonylpiperazin-1-yl)carbo...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP014TPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
KuDOS Pharmaceuticals Ltd.

LigandPNGBDBM27570(4-[(4-fluoro-3-{[4-(oxolan-3-ylcarbonyl)piperazin-...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP014TPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
KuDOS Pharmaceuticals Ltd.

LigandPNGBDBM27542(4-(3-(piperazine-1-carbonyl)benzyl)phthalazin-1(2H...)copy SMILEScopy InChI
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3QPXPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
KuDOS Pharmaceuticals Ltd.

LigandPNGBDBM27569(4-[(4-fluoro-3-{[4-(oxolan-2-ylcarbonyl)piperazin-...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP014TPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
KuDOS Pharmaceuticals Ltd.

LigandPNGBDBM27547(4-[(4-fluoro-3-{[4-(pyrimidin-2-yl)piperazin-1-yl]...)copy SMILEScopy InChI
Affinity DataIC50: 3nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP014TPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
KuDOS Pharmaceuticals Ltd.

LigandPNGBDBM27563(4-[(3-{[4-(cyclopropylmethyl)piperazin-1-yl]carbon...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP014TPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
KuDOS Pharmaceuticals Ltd.

LigandPNGBDBM27543(4-{[4-fluoro-3-(piperazin-1-ylcarbonyl)phenyl]meth...)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP014TPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
KuDOS Pharmaceuticals Ltd.

LigandPNGBDBM27662(4-[(3-{[4-(2-phenoxypropanoyl)piperazin-1-yl]carbo...)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3QPXPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
KuDOS Pharmaceuticals Ltd.

LigandPNGBDBM27553(4-({4-fluoro-3-[(4-phenylpiperazin-1-yl)carbonyl]p...)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP014TPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
KuDOS Pharmaceuticals Ltd.

LigandPNGBDBM27565(4-({4-fluoro-3-[(4-propanoylpiperazin-1-yl)carbony...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP014TPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
KuDOS Pharmaceuticals Ltd.

LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296847(2-(1-(4-cyano-3-ethoxyphenylsulfonyl)-2-methyl-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Antagonist activity against CRTh2 receptor in human eosinophils assessed as cell shape changeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
KuDOS Pharmaceuticals Ltd.

LigandPNGBDBM27562(4-({3-[(4-butylpiperazin-1-yl)carbonyl]-4-fluoroph...)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP014TPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296849(2-(1-(4-chloro-3-cyanophenylsulfonyl)-2-methyl-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Antagonist activity against CRTh2 receptor in human eosinophils assessed as cell shape changeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
KuDOS Pharmaceuticals Ltd.

LigandPNGBDBM27564(4-({3-[(4-acetylpiperazin-1-yl)carbonyl]-4-fluorop...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP014TPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
KuDOS Pharmaceuticals Ltd.

LigandPNGBDBM27561(4-({4-fluoro-3-[(4-propylpiperazin-1-yl)carbonyl]p...)copy SMILEScopy InChI
Affinity DataIC50: 6nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP014TPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
KuDOS Pharmaceuticals Ltd.

LigandPNGBDBM27560(4-({3-[(4-ethylpiperazin-1-yl)carbonyl]-4-fluoroph...)copy SMILEScopy InChI
Affinity DataIC50: 6nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP014TPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
KuDOS Pharmaceuticals Ltd.

LigandPNGBDBM27555(4-({3-[(4-benzoylpiperazin-1-yl)carbonyl]-4-fluoro...)copy SMILEScopy InChI
Affinity DataIC50: 6nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP014TPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
KuDOS Pharmaceuticals Ltd.

LigandPNGBDBM27551(4-[(4-fluoro-3-{[4-(morpholin-4-ylcarbonyl)piperaz...)copy SMILEScopy InChI
Affinity DataIC50: 6nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP014TPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
KuDOS Pharmaceuticals Ltd.

LigandPNGBDBM27535(4-[(4-fluoro-3-{[4-(2-hydroxyethyl)-1,4-diazepan-1...)copy SMILEScopy InChI
Affinity DataIC50: 7nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP014TPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
KuDOS Pharmaceuticals Ltd.

LigandPNGBDBM27533(4-(3-(1,4-diazepane-1-carbonyl)-4-fluorobenzyl)pht...)copy SMILEScopy InChI
Affinity DataIC50: 7nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP014TPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
KuDOS Pharmaceuticals Ltd.

LigandPNGBDBM27549(4-[(3-{[4-(ethanesulfonyl)piperazin-1-yl]carbonyl}...)copy SMILEScopy InChI
Affinity DataIC50: 8nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP014TPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
KuDOS Pharmaceuticals Ltd.

LigandPNGBDBM27661(4-({3-[(4-cyclopentanecarbonylpiperazin-1-yl)carbo...)copy SMILEScopy InChI
Affinity DataIC50: 8nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3QPXPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
KuDOS Pharmaceuticals Ltd.

LigandPNGBDBM27550(4-[(3-{[4-(morpholin-4-ylcarbonyl)piperazin-1-yl]c...)copy SMILEScopy InChI
Affinity DataIC50: 8nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP014TPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
KuDOS Pharmaceuticals Ltd.

LigandPNGBDBM27539(4-[(4-fluoro-3-{[4-(morpholin-4-ylcarbonyl)-1,4-di...)copy SMILEScopy InChI
Affinity DataIC50: 8nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP014TPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296850(2-(1-(3-cyano-4-fluorophenylsulfonyl)-2-methyl-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Antagonist activity against CRTh2 receptor in human eosinophils assessed as cell shape changeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
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