Compile Data Set for Download or QSAR
Found 302 with Last Name = 'ba?inka' and Initial = 'c'
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50246899((S)-2-(3-((S)-1-carboxy-5-(4-iodobenzamido)pentyl)...)copy SMILEScopy InChI
Affinity DataIC50: 0.0210nMAssay Description:Inhibition of recombinant human PSMA using [3H]NAAG as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by li...More data for this Ligand-Target Pair
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50468173(CHEMBL4284995)copy SMILEScopy InChI
Affinity DataIC50: 0.0750nMAssay Description:Inhibition of recombinant human PSMA using [3H]NAAG as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50468167(CHEMBL4280968)copy SMILEScopy InChI
Affinity DataIC50: 0.130nMAssay Description:Inhibition of recombinant human PSMA using [3H]NAAG as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50468163(CHEMBL4286872)copy SMILEScopy InChI
Affinity DataIC50: 0.150nMAssay Description:Inhibition of recombinant human PSMA using [3H]NAAG as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81GSCPubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50468164(CHEMBL4288368)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant human PSMA using [3H]NAAG as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81GSCPubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50468174(CHEMBL4277729)copy SMILEScopy InChI
Affinity DataIC50: 0.280nMAssay Description:Inhibition of recombinant human PSMA using [3H]NAAG as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81GSCPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50247556(CHEMBL4104117)copy SMILEScopy InChI
Affinity DataIC50: 0.290nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50571526(CHEMBL4863515)copy SMILES
Affinity DataIC50: 0.300nMAssay Description:Inhibition of recombinant human HDAC6 using Ac-GAK(Ac)-AMC as substrate preincubated for 10 mins followed by substrate addition and measured after 30...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222ZJFPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50274998(CHEMBL4126811)copy SMILEScopy InChI
Affinity DataIC50: 0.330nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 (1 to 1215 residues) expressed in baculovirus infected sf9 insect cells using p53 (379 to...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50468175(CHEMBL4291782)copy SMILEScopy InChI
Affinity DataIC50: 0.350nMAssay Description:Inhibition of recombinant human PSMA using [3H]NAAG as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50560908(CHEMBL4777296)copy SMILES
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human HDAC6 expressed in HEK293/T17 cells using pre-incubated for 10 mins before Ac-GAK(Ac)-AM substrate addition and measured after 30...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3QW7PubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50468177(CHEMBL4291245)copy SMILEScopy InChI
Affinity DataIC50: 0.460nMAssay Description:Inhibition of recombinant human PSMA using [3H]NAAG as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81GSCPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50279258(CHEMBL4177129)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human HDAC6 expressed in HEK293/T17 cells using pre-incubated for 10 mins before Ac-GAK(Ac)-AM substrate addition and measured after 30...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3QW7PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM417049(4-((6-chloro-3,4-dihydroquinolin-1(2H)-yl)methyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant human HDAC6 using Ac-GAK(Ac)-AMC as substrate preincubated for 10 mins followed by substrate addition and measured after 30...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222ZJFPubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50468178(CHEMBL4283406)copy SMILEScopy InChI
Affinity DataIC50: 0.640nMAssay Description:Inhibition of recombinant human PSMA using [3H]NAAG as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81GSCPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50571528(CHEMBL4846435)copy SMILES
Affinity DataIC50: 0.700nMAssay Description:Inhibition of recombinant human HDAC6 using Ac-GAK(Ac)-AMC as substrate preincubated for 10 mins followed by substrate addition and measured after 30...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222ZJFPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50571517(CHEMBL4846714)copy SMILES
Affinity DataIC50: 0.800nMAssay Description:Inhibition of recombinant human HDAC6 using Ac-GAK(Ac)-AMC as substrate preincubated for 10 mins followed by substrate addition and measured after 30...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222ZJFPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50252391(CHEMBL4080014)copy SMILEScopy InChI
Affinity DataIC50: 0.810nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 (1 to 1215 residues) expressed in baculovirus infected sf9 insect cells using RHK-K(Ac)-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50279258(CHEMBL4177129)copy SMILEScopy InChI
Affinity DataIC50: 0.870nMAssay Description:Evaluated for inhibition of Protease after after resynthesis and purificationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280B3GPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50571523(CHEMBL4857825)copy SMILES
Affinity DataIC50: 0.900nMAssay Description:Inhibition of recombinant human HDAC6 using Ac-GAK(Ac)-AMC as substrate preincubated for 10 mins followed by substrate addition and measured after 30...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222ZJFPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50560909(CHEMBL4759584)copy SMILES
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human HDAC6 expressed in HEK293/T17 cells using pre-incubated for 10 mins before Ac-GAK(Ac)-AM substrate addition and measured after 30...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3QW7PubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50468180(CHEMBL4294773)copy SMILEScopy InChI
Affinity DataIC50: 0.940nMAssay Description:Inhibition of recombinant human PSMA using [3H]NAAG as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81GSCPubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50468170(CHEMBL4292853)copy SMILEScopy InChI
Affinity DataIC50: 0.990nMAssay Description:Inhibition of recombinant human PSMA using [3H]NAAG as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50567701(CHEMBL4856735)copy SMILES
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human HDAC6 using Ac-GAK(Ac)-AMC as substrate preincubated for 10 mins followed by substrate addition and measured after 30...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222ZJFPubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50468168(CHEMBL4291603)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant human PSMA using [3H]NAAG as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81GSCPubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50468169(CHEMBL4281573)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of recombinant human PSMA using [3H]NAAG as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81GSCPubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50468172(CHEMBL4289458)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of recombinant human PSMA using [3H]NAAG as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81GSCPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50571527(CHEMBL4874875)copy SMILES
Affinity DataIC50: 1.30nMAssay Description:Inhibition of recombinant human HDAC6 using Ac-GAK(Ac)-AMC as substrate preincubated for 10 mins followed by substrate addition and measured after 30...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222ZJFPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of full length recombinant human HDAC1 expressed in baculovirus infected Sf9 insect cells using RHKKAc fluorogenic peptide as substrate pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222ZJFPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50398716(CHEMBL2179618 | US10227295, Compound 5g | US940985...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of recombinant human HDAC6 using Ac-GAK(Ac)-AMC as substrate preincubated for 10 mins followed by substrate addition and measured after 30...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222ZJFPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50398716(CHEMBL2179618 | US10227295, Compound 5g | US940985...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human HDAC6 expressed in HEK293/T17 cells using pre-incubated for 10 mins before Ac-GAK(Ac)-AM substrate addition and measured after 30...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3QW7PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM337665(US10227295, Compound JB7-19 | US9751832, Compound ...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of recombinant human full length HDAC6 expressed in baculovirus infected Sf9 insect cells using p53 (379 to 382 residues) derived RHKKAc a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280B3GPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM337666(US10227295, Compound JB7-20 | US9751832, Compound ...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of recombinant human full length HDAC6 expressed in baculovirus infected Sf9 insect cells using p53 (379 to 382 residues) derived RHKKAc a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280B3GPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50513915(CHEMBL4447715)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human HDAC6 expressed in HEK293T/17 cells using Ac-GAK(Ac)-AMC as substrate preincubated for 10 mins followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 (1 to 1215 residues) expressed in baculovirus infected sf9 insect cells using p53 (379 to...More data for this Ligand-Target Pair
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50468171(CHEMBL4294649)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Inhibition of recombinant human PSMA using [3H]NAAG as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81GSCPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM417049(4-((6-chloro-3,4-dihydroquinolin-1(2H)-yl)methyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 (1 to 1215 residues) expressed in baculovirus infected sf9 insect cells using p53 (379 to...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50468179(CHEMBL4279502)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Inhibition of recombinant human PSMA using [3H]NAAG as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50571521(CHEMBL4847663)copy SMILES
Affinity DataIC50: 2.40nMAssay Description:Inhibition of recombinant human HDAC6 using Ac-GAK(Ac)-AMC as substrate preincubated for 10 mins followed by substrate addition and measured after 30...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222ZJFPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM110036(US8609678, 2-((2-chlorophenyl)(phenyl)amino)-N-(7-...)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 insect cells assessed as decrease in re...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50571524(CHEMBL4847122)copy SMILES
Affinity DataIC50: 2.70nMAssay Description:Inhibition of recombinant human HDAC6 using Ac-GAK(Ac)-AMC as substrate preincubated for 10 mins followed by substrate addition and measured after 30...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222ZJFPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Inhibition of recombinant human full length HDAC6 expressed in baculovirus infected Sf9 insect cells using p53 (379 to 382 residues) derived RHKKAc a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280B3GPubMedDrugBank
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50468162(CHEMBL4286751)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Inhibition of recombinant human PSMA using [3H]NAAG as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81GSCPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM417049(4-((6-chloro-3,4-dihydroquinolin-1(2H)-yl)methyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Inhibition of full length recombinant human HDAC1 expressed in baculovirus infected Sf9 insect cells using RHKKAc fluorogenic peptide as substrate pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222ZJFPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50571522(CHEMBL4859648)copy SMILES
Affinity DataIC50: 2.90nMAssay Description:Inhibition of recombinant human HDAC6 using Ac-GAK(Ac)-AMC as substrate preincubated for 10 mins followed by substrate addition and measured after 30...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222ZJFPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM249366(US9464073, 003 | US9884850, Compound 3)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3QW7PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50261816(CHEMBL511749 | tert-butyl 4-(3-((7-(hydroxyamino)-...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of recombinant full length C-terminal His/FLAG tagged human HDAC1 (1 to 482 residues) expressed in baculovirus infected sf9 insect cells u...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM417070(US10456394, Example 7)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMAssay Description:Inhibition of full length recombinant human HDAC1 expressed in baculovirus infected Sf9 insect cells using RHKKAc fluorogenic peptide as substrate pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222ZJFPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM417068(US10456394, Example 6)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:Inhibition of full length recombinant human HDAC1 expressed in baculovirus infected Sf9 insect cells using RHKKAc fluorogenic peptide as substrate pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222ZJFPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50398716(CHEMBL2179618 | US10227295, Compound 5g | US940985...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human HDAC6 expressed in HEK293T/17 cells using Ac-GAK(Ac)-AMC as substrate preincubated for 10 mins followed by substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
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