Compile Data Set for Download or QSAR
Found 114 with Last Name = 'czech' and Initial = 'c'
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50477148(CHEMBL235870)copy SMILEScopy InChI
Affinity DataIC50: 0.00200nMAssay Description:Inhibition of human gamma secretase in HEK293 cells by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4SNKPubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50477143(CHEMBL392113)copy SMILEScopy InChI
Affinity DataIC50: 0.0150nMAssay Description:Inhibition of human gamma secretase assessed as amyloid-beta40 peptide production in HEK293 cells by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4SNKPubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50477136(CHEMBL235659)copy SMILEScopy InChI
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of human gamma secretase assessed as amyloid-beta40 peptide production in HEK293 cells by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4SNKPubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50477131(CHEMBL235869)copy SMILEScopy InChI
Affinity DataIC50: 0.0240nMAssay Description:Inhibition of human gamma secretase in HEK293 cells by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4SNKPubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50477131(CHEMBL235869)copy SMILEScopy InChI
Affinity DataIC50: 0.0370nMAssay Description:Inhibition of human gamma secretase assessed as amyloid-beta40 peptide production in HEK293 cells by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4SNKPubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50477136(CHEMBL235659)copy SMILEScopy InChI
Affinity DataIC50: 0.0420nMAssay Description:Inhibition of human gamma secretase in HEK293 cells by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4SNKPubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50477143(CHEMBL392113)copy SMILEScopy InChI
Affinity DataIC50: 0.0750nMAssay Description:Inhibition of human gamma secretase in HEK293 cells by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4SNKPubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50477134(CHEMBL393542)copy SMILEScopy InChI
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of human gamma secretase assessed as amyloid-beta40 peptide production in HEK293 cells by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4SNKPubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50477134(CHEMBL393542)copy SMILEScopy InChI
Affinity DataIC50: 0.210nMAssay Description:Inhibition of human gamma secretase in HEK293 cells by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4SNKPubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Technische Universit£t Darmstadt

Curated by ChEMBL
LigandPNGBDBM50402408(CHEMBL2203332)copy SMILEScopy InChI
Affinity DataIC50: 1.41nMAssay Description:Displacement of thiazine red R from human Tau aggregate expressed in Escherichia coli after 30 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ62PCPubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50477145(CHEMBL235648)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human gamma secretase in HEK293 cells by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4SNKPubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50477146(CHEMBL428374)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human gamma secretase in HEK293 cells by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4SNKPubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50477142(CHEMBL235226)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human gamma secretase in HEK293 cells by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4SNKPubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Technische Universit£t Darmstadt

Curated by ChEMBL
LigandPNGBDBM50398203(CHEMBL2181533)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Displacement of thiazene red from tau aggregateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC33HQPubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Technische Universit£t Darmstadt

Curated by ChEMBL
LigandPNGBDBM50398204(CHEMBL2181532)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Displacement of thiazene red from tau aggregateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC33HQPubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50478057(CHEMBL256059)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human gamma secretase in HEK293 cells assessed as reduction of amyloid beta level by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J105X3PubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50477145(CHEMBL235648)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human gamma secretase assessed as amyloid-beta40 peptide production in HEK293 cells by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4SNKPubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50477147(CHEMBL235216)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human gamma secretase assessed as amyloid-beta40 peptide production in HEK293 cells by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4SNKPubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50477146(CHEMBL428374)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human gamma secretase assessed as amyloid-beta40 peptide production in HEK293 cells by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4SNKPubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50477137(CHEMBL235427)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:Inhibition of human gamma secretase assessed as amyloid-beta40 peptide production in HEK293 cells by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4SNKPubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50477147(CHEMBL235216)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human gamma secretase in HEK293 cells by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4SNKPubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Technische Universit£t Darmstadt

Curated by ChEMBL
LigandPNGBDBM50398207(CHEMBL2181045)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Displacement of thiazene red from tau aggregateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC33HQPubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50478077(CHEMBL403332)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human gamma secretase in HEK293 cells assessed as reduction of amyloid beta level by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J105X3PubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Technische Universit£t Darmstadt

Curated by ChEMBL
LigandPNGBDBM50402407(CHEMBL2207756)copy SMILEScopy InChI
Affinity DataIC50: 5.10nMAssay Description:Displacement of thiazine red R from human Tau aggregate expressed in Escherichia coli after 30 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ62PCPubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50477149(CHEMBL430169)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMAssay Description:Inhibition of human gamma secretase assessed as amyloid-beta40 peptide production in HEK293 cells by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4SNKPubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50477132(CHEMBL267960)copy SMILEScopy InChI
Affinity DataIC50: 5.70nMAssay Description:Inhibition of human gamma secretase assessed as amyloid-beta40 peptide production in HEK293 cells by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4SNKPubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Technische Universit£t Darmstadt

Curated by ChEMBL
LigandPNGBDBM50398209(CHEMBL2181041)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Displacement of thiazene red from tau aggregateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC33HQPubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50478058(CHEMBL429938)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human gamma secretase in HEK293 cells assessed as reduction of amyloid beta level by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J105X3PubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50477132(CHEMBL267960)copy SMILEScopy InChI
Affinity DataIC50: 6.30nMAssay Description:Inhibition of human gamma secretase in HEK293 cells by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4SNKPubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50477140(CHEMBL267959)copy SMILEScopy InChI
Affinity DataIC50: 7.10nMAssay Description:Inhibition of human gamma secretase in HEK293 cells by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4SNKPubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50478061(CHEMBL439242)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of human gamma secretase in HEK293 cells assessed as reduction of amyloid beta level by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J105X3PubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50477142(CHEMBL235226)copy SMILEScopy InChI
Affinity DataIC50: 8.60nMAssay Description:Inhibition of human gamma secretase assessed as amyloid-beta40 peptide production in HEK293 cells by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4SNKPubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50477140(CHEMBL267959)copy SMILEScopy InChI
Affinity DataIC50: 8.70nMAssay Description:Inhibition of human gamma secretase assessed as amyloid-beta40 peptide production in HEK293 cells by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4SNKPubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50477137(CHEMBL235427)copy SMILEScopy InChI
Affinity DataIC50: 8.80nMAssay Description:Inhibition of human gamma secretase in HEK293 cells by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4SNKPubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50477133(CHEMBL391420)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human gamma secretase in HEK293 cells by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4SNKPubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50477138(CHEMBL400637)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of human gamma secretase assessed as amyloid-beta40 peptide production in HEK293 cells by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4SNKPubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Technische Universit£t Darmstadt

Curated by ChEMBL
LigandPNGBDBM50398210(CHEMBL2181039)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Displacement of thiazene red from tau aggregateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC33HQPubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50477138(CHEMBL400637)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of human gamma secretase in HEK293 cells by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4SNKPubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50478075(CHEMBL271880)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of human gamma secretase in HEK293 cells assessed as reduction of amyloid beta level by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J105X3PubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Technische Universit£t Darmstadt

Curated by ChEMBL
LigandPNGBDBM50398205(CHEMBL2181531)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Displacement of thiazene red from tau aggregateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC33HQPubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50478064(CHEMBL402950)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human gamma secretase in HEK293 cells assessed as reduction of amyloid beta level by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J105X3PubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50477139(CHEMBL400638)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human gamma secretase in HEK293 cells by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4SNKPubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50478084(CHEMBL256388)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human gamma secretase in HEK293 cells assessed as reduction of amyloid beta level by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J105X3PubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50477139(CHEMBL400638)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human gamma secretase assessed as amyloid-beta40 peptide production in HEK293 cells by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4SNKPubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50477133(CHEMBL391420)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of human gamma secretase assessed as amyloid-beta40 peptide production in HEK293 cells by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4SNKPubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50477141(CHEMBL236083)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of human gamma secretase assessed as amyloid-beta40 peptide production in HEK293 cells by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4SNKPubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50477149(CHEMBL430169)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of human gamma secretase in HEK293 cells by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4SNKPubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50477141(CHEMBL236083)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of human gamma secretase in HEK293 cells by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4SNKPubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50478063(CHEMBL256794)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human gamma secretase in HEK293 cells assessed as reduction of amyloid beta level by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J105X3PubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50478059(CHEMBL256596)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of human gamma secretase in HEK293 cells assessed as reduction of amyloid beta level by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J105X3PubMed
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