TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Albert Ludwigs University Freiburg
Curated by ChEMBL
Albert Ludwigs University Freiburg
Curated by ChEMBL
Affinity DataIC50: 330nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged VEGFR2 (D807 to V1356 residues) expressed in sf9 cells using Poly(Glu,Tyr) 4:1 as substrate aft...More data for this Ligand-Target Pair
TargetAlcohol dehydrogenase 1A(Homo sapiens (Human))
Albert Ludwigs University Freiburg
Curated by ChEMBL
Albert Ludwigs University Freiburg
Curated by ChEMBL
Affinity DataIC50: 460nMAssay Description:Inhibition of ADH1 (unknown origin) preincubated for 2 hrs followed by substrate/NAD+ additionMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Albert Ludwigs University Freiburg
Curated by ChEMBL
Albert Ludwigs University Freiburg
Curated by ChEMBL
Affinity DataIC50: 530nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged VEGFR2 (D807 to V1356 residues) expressed in sf9 cells using Poly(Glu,Tyr) 4:1 as substrate aft...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Albert Ludwigs University Freiburg
Curated by ChEMBL
Albert Ludwigs University Freiburg
Curated by ChEMBL
Affinity DataIC50: 540nMAssay Description:Inhibition of recombinant human N-terminal GST/His6-tagged ABL2 (M1 to P650 residues) expressed in sf9 cells using Poly(Glu,Tyr) 4:1 as substrate aft...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Albert Ludwigs University Freiburg
Curated by ChEMBL
Albert Ludwigs University Freiburg
Curated by ChEMBL
Affinity DataIC50: 685nMAssay Description:Inhibition of recombinant human N-terminal GST/His6-tagged ABL2 (M1 to P650 residues) expressed in sf9 cells using Poly(Glu,Tyr) 4:1 as substrate aft...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Albert Ludwigs University Freiburg
Curated by ChEMBL
Albert Ludwigs University Freiburg
Curated by ChEMBL
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged VEGFR1 (K784 to I1338 residues) expressed in sf9 cells using Poly(Glu,Tyr) 4:1 as substrate aft...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Albert Ludwigs University Freiburg
Curated by ChEMBL
Albert Ludwigs University Freiburg
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged VEGFR1 (K784 to I1338 residues) expressed in sf9 cells using Poly(Glu,Tyr) 4:1 as substrate aft...More data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Albert Ludwigs University Freiburg
Curated by ChEMBL
Albert Ludwigs University Freiburg
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant human N-terminal GST/His6-tagged c-KIT (T544 to V976 residues) expressed in sf9 cells using Poly(Glu,Tyr) 4:1 as substrate ...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Albert Ludwigs University Freiburg
Curated by ChEMBL
Albert Ludwigs University Freiburg
Curated by ChEMBL
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of recombinant human N-terminal GST/His6-tagged VEGFR3 (N799 to R1298 residues) expressed in sf9 cells using Poly(Glu,Tyr) 4:1 as substrat...More data for this Ligand-Target Pair
TargetAlcohol dehydrogenase 1A(Homo sapiens (Human))
Albert Ludwigs University Freiburg
Curated by ChEMBL
Albert Ludwigs University Freiburg
Curated by ChEMBL
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of ADH1 (unknown origin) preincubated for 2 hrs followed by substrate/NAD+ additionMore data for this Ligand-Target Pair
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 2(Rattus norvegicus)
Albert Ludwigs University Freiburg
Curated by ChEMBL
Albert Ludwigs University Freiburg
Curated by ChEMBL
Affinity DataIC50: 6.72E+3nMAssay Description:Inhibition of Wistar rat heart SERCA2a after 1 hrMore data for this Ligand-Target Pair
TargetSodium/potassium-transporting ATPase subunit alpha-1(RAT)
Albert Ludwigs University Freiburg
Curated by ChEMBL
Albert Ludwigs University Freiburg
Curated by ChEMBL
Affinity DataIC50: 8.23E+3nMAssay Description:Inhibition of Wistar rat kidney Na+,K+-ATPase alpha1 after 2 hrsMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Albert Ludwigs University Freiburg
Curated by ChEMBL
Albert Ludwigs University Freiburg
Curated by ChEMBL
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of recombinant human N-terminal GST/His6-tagged c-KIT (T544 to V976 residues) expressed in sf9 cells using Poly(Glu,Tyr) 4:1 as substrate ...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Albert Ludwigs University Freiburg
Curated by ChEMBL
Albert Ludwigs University Freiburg
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human N-terminal GST/His6-tagged VEGFR3 (N799 to R1298 residues) expressed in sf9 cells using Poly(Glu,Tyr) 4:1 as substrat...More data for this Ligand-Target Pair
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Rattus norvegicus)
Albert Ludwigs University Freiburg
Curated by ChEMBL
Albert Ludwigs University Freiburg
Curated by ChEMBL
Affinity DataIC50: 1.69E+4nMAssay Description:Inhibition of Wistar rat EDL muscle SERCA1a after 1 hrMore data for this Ligand-Target Pair
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Albert Ludwigs University Freiburg
Curated by ChEMBL
Albert Ludwigs University Freiburg
Curated by ChEMBL
Affinity DataKd: 5.00E+4nMAssay Description:Binding affinity to rabbit hind leg muscle SERCA1a by pyruvate kinase and lactate dehydrogenase coupled assayMore data for this Ligand-Target Pair
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Albert Ludwigs University Freiburg
Curated by ChEMBL
Albert Ludwigs University Freiburg
Curated by ChEMBL
Affinity DataKd: 1.01E+4nMAssay Description:Binding affinity to rabbit skeletal muscle SERCA1a preincubated for 5 mins followed by Mg-ATP addition measured over 6 mins by spectrophotometric ana...More data for this Ligand-Target Pair
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Albert Ludwigs University Freiburg
Curated by ChEMBL
Albert Ludwigs University Freiburg
Curated by ChEMBL
Affinity DataKd: 3.21E+4nMAssay Description:Binding affinity to rabbit skeletal muscle SERCA1a preincubated for 5 mins followed by Mg-ATP addition measured over 6 mins by spectrophotometric ana...More data for this Ligand-Target Pair
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Albert Ludwigs University Freiburg
Curated by ChEMBL
Albert Ludwigs University Freiburg
Curated by ChEMBL
Affinity DataKd: 1.03E+5nMAssay Description:Binding affinity to rabbit skeletal muscle SERCA1a preincubated for 5 mins followed by Mg-ATP addition measured over 6 mins by spectrophotometric ana...More data for this Ligand-Target Pair
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Albert Ludwigs University Freiburg
Curated by ChEMBL
Albert Ludwigs University Freiburg
Curated by ChEMBL
Affinity DataKd: 9.65E+4nMAssay Description:Binding affinity to rabbit skeletal muscle SERCA1a preincubated for 5 mins followed by Mg-ATP addition measured over 6 mins by spectrophotometric ana...More data for this Ligand-Target Pair
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Albert Ludwigs University Freiburg
Curated by ChEMBL
Albert Ludwigs University Freiburg
Curated by ChEMBL
Affinity DataKd: 7.50E+3nMAssay Description:Binding affinity to rabbit skeletal muscle SERCA1a preincubated for 5 mins followed by Mg-ATP addition measured over 6 mins by spectrophotometric ana...More data for this Ligand-Target Pair
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Albert Ludwigs University Freiburg
Curated by ChEMBL
Albert Ludwigs University Freiburg
Curated by ChEMBL
Affinity DataKd: 3.15E+4nMAssay Description:Binding affinity to rabbit skeletal muscle SERCA1a preincubated for 5 mins followed by Mg-ATP addition measured over 6 mins by spectrophotometric ana...More data for this Ligand-Target Pair
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Albert Ludwigs University Freiburg
Curated by ChEMBL
Albert Ludwigs University Freiburg
Curated by ChEMBL
Affinity DataKd: >1.00E+5nMAssay Description:Binding affinity to rabbit skeletal muscle SERCA1a preincubated for 5 mins followed by Mg-ATP addition measured over 6 mins by spectrophotometric ana...More data for this Ligand-Target Pair
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Albert Ludwigs University Freiburg
Curated by ChEMBL
Albert Ludwigs University Freiburg
Curated by ChEMBL
Affinity DataKd: 0.200nMAssay Description:Binding affinity to rabbit skeletal muscle SERCA1a preincubated for 5 mins followed by Mg-ATP addition measured over 6 mins by spectrophotometric ana...More data for this Ligand-Target Pair
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Albert Ludwigs University Freiburg
Curated by ChEMBL
Albert Ludwigs University Freiburg
Curated by ChEMBL
Affinity DataKd: 2.70E+4nMAssay Description:Binding affinity to rabbit hind leg muscle SERCA1a by pyruvate kinase and lactate dehydrogenase coupled assayMore data for this Ligand-Target Pair
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Albert Ludwigs University Freiburg
Curated by ChEMBL
Albert Ludwigs University Freiburg
Curated by ChEMBL
Affinity DataKd: 2.00E+3nMAssay Description:Binding affinity to rabbit skeletal muscle SERCA1a preincubated for 5 mins followed by Mg-ATP addition measured over 6 mins by spectrophotometric ana...More data for this Ligand-Target Pair
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Albert Ludwigs University Freiburg
Curated by ChEMBL
Albert Ludwigs University Freiburg
Curated by ChEMBL
Affinity DataKd: 4.81E+4nMAssay Description:Binding affinity to rabbit skeletal muscle SERCA1a preincubated for 5 mins followed by Mg-ATP addition measured over 6 mins by spectrophotometric ana...More data for this Ligand-Target Pair
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Albert Ludwigs University Freiburg
Curated by ChEMBL
Albert Ludwigs University Freiburg
Curated by ChEMBL
Affinity DataKd: 2.23E+4nMAssay Description:Binding affinity to rabbit skeletal muscle SERCA1a preincubated for 5 mins followed by Mg-ATP addition measured over 6 mins by spectrophotometric ana...More data for this Ligand-Target Pair
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Albert Ludwigs University Freiburg
Curated by ChEMBL
Albert Ludwigs University Freiburg
Curated by ChEMBL
Affinity DataKd: 2.01E+4nMAssay Description:Binding affinity to rabbit skeletal muscle SERCA1a preincubated for 5 mins followed by Mg-ATP addition measured over 6 mins by spectrophotometric ana...More data for this Ligand-Target Pair