Compile Data Set for Download or QSAR
Found 44 with Last Name = 'fiorilla' and Initial = 'c'
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research Inc.

Curated by ChEMBL
LigandPNGBDBM50426420(CHEMBL2322027)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of Bcl-2/biotinylated BAK (unknown origin) interaction incubated for 1 hr by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5WRFPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research Inc.

Curated by ChEMBL
LigandPNGBDBM50426417(CHEMBL2326745)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of Bcl-2/biotinylated BAK (unknown origin) interaction incubated for 1 hr by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5WRFPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research Inc.

Curated by ChEMBL
LigandPNGBDBM21447(4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of Bcl-2/biotinylated BAK (unknown origin) interaction incubated for 1 hr by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5WRFPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research Inc.

Curated by ChEMBL
LigandPNGBDBM50426413(CHEMBL2322021)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of Bcl-xL/BAK (unknown origin) interactionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5WRFPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research Inc.

Curated by ChEMBL
LigandPNGBDBM50426414(CHEMBL2322020)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of Bcl-xL/BAK (unknown origin) interactionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5WRFPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research Inc.

Curated by ChEMBL
LigandPNGBDBM50426417(CHEMBL2326745)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of Bcl-xL/BAK (unknown origin) interactionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5WRFPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research Inc.

Curated by ChEMBL
LigandPNGBDBM50426421(CHEMBL2322026)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of Bcl-2/biotinylated BAK (unknown origin) interaction incubated for 1 hr by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5WRFPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research Inc.

Curated by ChEMBL
LigandPNGBDBM50426418(CHEMBL2326744)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of Bcl-2/biotinylated BAK (unknown origin) interaction incubated for 1 hr by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5WRFPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research Inc.

Curated by ChEMBL
LigandPNGBDBM50426413(CHEMBL2322021)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of Bcl-2/biotinylated BAK (unknown origin) interaction incubated for 1 hr by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5WRFPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research Inc.

Curated by ChEMBL
LigandPNGBDBM50426416(CHEMBL2326746)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of Bcl-2/biotinylated BAK (unknown origin) interaction incubated for 1 hr by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5WRFPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research Inc.

Curated by ChEMBL
LigandPNGBDBM50426415(CHEMBL2326747)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of Bcl-2/biotinylated BAK (unknown origin) interaction incubated for 1 hr by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5WRFPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research Inc.

Curated by ChEMBL
LigandPNGBDBM50426412(CHEMBL2322022)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of Bcl-2/biotinylated BAK (unknown origin) interaction incubated for 1 hr by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5WRFPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research Inc.

Curated by ChEMBL
LigandPNGBDBM50426412(CHEMBL2322022)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Inhibition of Bcl-xL/BAK (unknown origin) interactionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5WRFPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research Inc.

Curated by ChEMBL
LigandPNGBDBM50426423(CHEMBL2322024)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:Inhibition of Bcl-2/biotinylated BAK (unknown origin) interaction incubated for 1 hr by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5WRFPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research Inc.

Curated by ChEMBL
LigandPNGBDBM50426416(CHEMBL2326746)copy SMILEScopy InChI
Affinity DataIC50: 74nMAssay Description:Inhibition of Bcl-xL/BAK (unknown origin) interactionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5WRFPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research Inc.

Curated by ChEMBL
LigandPNGBDBM50426415(CHEMBL2326747)copy SMILEScopy InChI
Affinity DataIC50: 115nMAssay Description:Inhibition of Bcl-xL/BAK (unknown origin) interactionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5WRFPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research Inc.

Curated by ChEMBL
LigandPNGBDBM50426414(CHEMBL2322020)copy SMILEScopy InChI
Affinity DataIC50: 142nMAssay Description:Inhibition of Bcl-2/biotinylated BAK (unknown origin) interaction incubated for 1 hr by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5WRFPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research Inc.

Curated by ChEMBL
LigandPNGBDBM50426419(CHEMBL2322029)copy SMILEScopy InChI
Affinity DataIC50: 740nMAssay Description:Inhibition of Bcl-2/biotinylated BAK (unknown origin) interaction incubated for 1 hr by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5WRFPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Harbor Branch Oceanographic Institute at Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50316411(CHEMBL1094578 | gymnochrome F)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of MCL1 binding to Bak by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ32TBPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research Inc.

Curated by ChEMBL
LigandPNGBDBM50426424(CHEMBL2322023)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of Bcl-2/biotinylated BAK (unknown origin) interaction incubated for 1 hr by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5WRFPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Harbor Branch Oceanographic Institute at Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50232491(3,5-dibromo-2-(2',4'-dibromophenoxy)phenol | 3,5-d...)copy SMILEScopy InChI
Affinity DataIC50: 4.78E+3nMAssay Description:Inhibition of Bak binding to Mcl-1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4NMDPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research Inc.

Curated by ChEMBL
LigandPNGBDBM50426422(CHEMBL2322025)copy SMILEScopy InChI
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of Bcl-2/biotinylated BAK (unknown origin) interaction incubated for 1 hr by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5WRFPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Harbor Branch Oceanographic Institute at Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50316410(CHEMBL1094577 | gymnochrome E)copy SMILEScopy InChI
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of human HDAC1 assessed as [3H]acetate release after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ32TBPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Harbor Branch Oceanographic Institute at Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50316814(CHEMBL1097104 | cryptosphaerolide)copy SMILEScopy InChI
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of Mcl1 protein by Mcl1/Bak fluorescence resonance assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR1ZCXPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Harbor Branch Oceanographic Institute at Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50292443(3,4,5-tribromo-2-(2', 4'-dibromo-phenoxy)phenol | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of Bak binding to Mcl-1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4NMDPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Harbor Branch Oceanographic Institute at Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50316815((1R,3S,4R,8S,10R,11S,14R)-4-methoxy-10,11-dimethyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of Mcl1 protein by Mcl1/Bak fluorescence resonance assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR1ZCXPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Harbor Branch Oceanographic Institute at Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50135851(2,3,4,5-tetrabromo-6-(3,5-dibromo-2-hydroxy-phenox...)copy SMILEScopy InChI
Affinity DataIC50: 1.48E+4nMAssay Description:Inhibition of Bak binding to Mcl-1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4NMDPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Harbor Branch Oceanographic Institute at Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50480591(CHEMBL374480)copy SMILEScopy InChI
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibition of Bak binding to Mcl-1 by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4NMDPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Harbor Branch Oceanographic Institute at Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50480592(CHEMBL149159)copy SMILEScopy InChI
Affinity DataIC50: 1.67E+4nMAssay Description:Inhibition of Bak binding to Mcl-1 by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4NMDPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Harbor Branch Oceanographic Institute at Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50480589(CHEMBL558681)copy SMILEScopy InChI
Affinity DataIC50: 1.67E+4nMAssay Description:Inhibition of Bak binding to Mcl-1 by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4NMDPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Harbor Branch Oceanographic Institute at Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50150788(2,3,5-tribromo-6-(3,5-dibromo-2-hydroxy-phenoxy)-p...)copy SMILEScopy InChI
Affinity DataIC50: 1.67E+4nMAssay Description:Inhibition of Bak binding to Mcl-1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4NMDPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Harbor Branch Oceanographic Institute at Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50480593(CHEMBL572122)copy SMILEScopy InChI
Affinity DataIC50: 1.67E+4nMAssay Description:Inhibition of Bak binding to Mcl-1 by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4NMDPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Harbor Branch Oceanographic Institute at Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50480590(CHEMBL402539)copy SMILEScopy InChI
Affinity DataIC50: 1.72E+4nMAssay Description:Inhibition of Bak binding to Mcl-1 by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4NMDPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Harbor Branch Oceanographic Institute at Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM57619(2,4-dibromo-6-(2,4-dibromophenoxy)phenol | 2-[2,4-...)copy SMILEScopy InChI
Affinity DataIC50: 1.77E+4nMAssay Description:Inhibition of Bak binding to Mcl-1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4NMDPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research Inc.

Curated by ChEMBL
LigandPNGBDBM50426418(CHEMBL2326744)copy SMILEScopy InChI
Affinity DataKd:  5nMAssay Description:Binding affinity to Bcl-2 (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5WRFPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research Inc.

Curated by ChEMBL
LigandPNGBDBM50426414(CHEMBL2322020)copy SMILEScopy InChI
Affinity DataKd:  104nMAssay Description:Binding affinity to Bcl-2 (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5WRFPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research Inc.

Curated by ChEMBL
LigandPNGBDBM50426415(CHEMBL2326747)copy SMILEScopy InChI
Affinity DataKd:  2nMAssay Description:Binding affinity to Bcl-2 (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5WRFPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research Inc.

Curated by ChEMBL
LigandPNGBDBM50426421(CHEMBL2322026)copy SMILEScopy InChI
Affinity DataKd:  8nMAssay Description:Binding affinity to Bcl-2 (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5WRFPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research Inc.

Curated by ChEMBL
LigandPNGBDBM50426417(CHEMBL2326745)copy SMILEScopy InChI
Affinity DataKd:  7nMAssay Description:Binding affinity to Bcl-2 (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5WRFPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research Inc.

Curated by ChEMBL
LigandPNGBDBM50426412(CHEMBL2322022)copy SMILEScopy InChI
Affinity DataKd:  10nMAssay Description:Binding affinity to Bcl-2 (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5WRFPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research Inc.

Curated by ChEMBL
LigandPNGBDBM50426420(CHEMBL2322027)copy SMILEScopy InChI
Affinity DataKd:  14nMAssay Description:Binding affinity to Bcl-2 (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5WRFPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research Inc.

Curated by ChEMBL
LigandPNGBDBM50426413(CHEMBL2322021)copy SMILEScopy InChI
Affinity DataKd:  17nMAssay Description:Binding affinity to Bcl-2 (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5WRFPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research Inc.

Curated by ChEMBL
LigandPNGBDBM21447(4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...)copy SMILEScopy InChI
Affinity DataKd:  0.600nMAssay Description:Binding affinity to Bcl-2 (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5WRFPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research Inc.

Curated by ChEMBL
LigandPNGBDBM50426416(CHEMBL2326746)copy SMILEScopy InChI
Affinity DataKd:  3nMAssay Description:Binding affinity to Bcl-2 (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5WRFPubMed