Compile Data Set for Download or QSAR
Found 18 with Last Name = 'gai' and Initial = 'c'
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))TBA
LigandPNGBDBM250082(US9447106, 27b (peak 2) | US9556188, Compound 27a)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6W53PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))TBA
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
LigandPNGBDBM50539763(Adagrasib | Mrtx-849 | Mrtx849)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6W53PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))TBA
LigandPNGBDBM50175583(ACP-196 | Acalabrutinib | US10239883, Example 6 | ...)copy SMILEScopy InChI
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)copy SMILEScopy InChI
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))TBA
LigandPNGBDBM202554((E/Z)-2-cyano-N,N-dimethyl-3-(5-(1-((1S,2R)-2-meth...)copy SMILES
Affinity DataIC50: 17nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6W53PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50160870(CHEMBL3787344 | US11896597, Compound EGF816 | WO20...)copy SMILEScopy InChI
Affinity DataIC50: 31nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6W53PubMed
TargetCyclin-dependent kinase 7(Homo sapiens (Human))TBA
LigandPNGBDBM50526795(CHEMBL4450322)copy SMILEScopy InChI
Affinity DataIC50: 54nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6W53PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50511933(CHEMBL4518287)copy SMILEScopy InChI
Affinity DataIC50: 160nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6W53PubMed
TargetCyclin-dependent kinase 7(Homo sapiens (Human))TBA
LigandPNGBDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)copy SMILEScopy InChI
Affinity DataIC50: 240nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6W53PubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)TBA
LigandPNGBDBM50505278(CHEMBL4578515)copy SMILEScopy InChI
Affinity DataIC50: 400nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6W53PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM112499(DACOMITINIB | US8623883, No. 2 | WO2022090481, Exa...)copy SMILEScopy InChI
Affinity DataIC50: 440nMMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)TBA
LigandPNGBDBM50505277(CHEMBL4553027)copy SMILEScopy InChI
Affinity DataIC50: 480nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6W53PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50523417(CHEMBL4564592)copy SMILEScopy InChI
Affinity DataKd:  5.00E+4nMAssay Description:Binding affinity to full-length human CDK2 expressed in Escherichia coli BL21 (DE3) pLysS cells by isothermal titration calorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetCyclin-dependent kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50523416(CHEMBL4449374)copy SMILEScopy InChI
Affinity DataKd:  3.50E+5nMAssay Description:Binding affinity to full-length human CDK2 expressed in Escherichia coli BL21 (DE3) pLysS cells by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN77BMPubMed