Compile Data Set for Download or QSAR
Found 28 with Last Name = 'geroni' and Initial = 'c'
TargetAdenosine deaminase(Homo sapiens (Human))
Universit£ di Camerino

Curated by ChEMBL
LigandPNGBDBM50034908((2R,3S)-3-((R)-6-Amino-purin-9-yl)-nonan-2-ol | (2...)copy SMILEScopy InChI
Affinity DataKi:  4.30nMAssay Description:Inhibition constant (Ki) against Human erythrocyte adenosine deaminaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X067M7PubMed
TargetAdenosine deaminase(Homo sapiens (Human))
Universit£ di Camerino

Curated by ChEMBL
LigandPNGBDBM50011575(3-(4-Amino-imidazo[4,5-c]pyridin-1-yl)-nonan-2-ol ...)copy SMILEScopy InChI
Affinity DataKi:  6.30nMAssay Description:Inhibition constant (Ki) against Human erythrocyte adenosine deaminaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X067M7PubMed
TargetAdenosine deaminase(Bos taurus (bovine))
Universit£ di Camerino

Curated by ChEMBL
LigandPNGBDBM50034908((2R,3S)-3-((R)-6-Amino-purin-9-yl)-nonan-2-ol | (2...)copy SMILEScopy InChI
Affinity DataKi:  7nMAssay Description:Inhibition constant (Ki) against calf intestine adenosine deaminaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X067M7PubMed
TargetAdenosine deaminase(Bos taurus (bovine))
Universit£ di Camerino

Curated by ChEMBL
LigandPNGBDBM50011575(3-(4-Amino-imidazo[4,5-c]pyridin-1-yl)-nonan-2-ol ...)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Inhibition constant (Ki) against calf intestine adenosine deaminaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X067M7PubMed
TargetAdenosine deaminase(Homo sapiens (Human))
Universit£ di Camerino

Curated by ChEMBL
LigandPNGBDBM50011591(3-(7-Amino-imidazo[4,5-b]pyridin-3-yl)-nonan-2-ol ...)copy SMILEScopy InChI
Affinity DataKi:  120nMAssay Description:Inhibition constant (Ki) against Human erythrocyte adenosine deaminaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X067M7PubMed
TargetAdenosine deaminase(Bos taurus (bovine))
Universit£ di Camerino

Curated by ChEMBL
LigandPNGBDBM50011591(3-(7-Amino-imidazo[4,5-b]pyridin-3-yl)-nonan-2-ol ...)copy SMILEScopy InChI
Affinity DataKi:  160nMAssay Description:Inhibition constant (Ki) against calf intestine adenosine deaminaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X067M7PubMed
TargetAdenosine deaminase(Homo sapiens (Human))
Universit£ di Camerino

Curated by ChEMBL
LigandPNGBDBM50011565(3-(4-Amino-benzoimidazol-1-yl)-nonan-2-ol | CHEMBL...)copy SMILEScopy InChI
Affinity DataKi:  1.50E+4nMAssay Description:Inhibition constant (Ki) against Human erythrocyte adenosine deaminaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X067M7PubMed
TargetAdenosine deaminase(Bos taurus (bovine))
Universit£ di Camerino

Curated by ChEMBL
LigandPNGBDBM50011565(3-(4-Amino-benzoimidazol-1-yl)-nonan-2-ol | CHEMBL...)copy SMILEScopy InChI
Affinity DataKi:  7.10E+4nMAssay Description:Inhibition constant (Ki) against calf intestine adenosine deaminaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X067M7PubMed
TargetAdenosine deaminase(Homo sapiens (Human))
Universit£ di Camerino

Curated by ChEMBL
LigandPNGBDBM50011566(3-(4-Amino-pyrrolo[2,3-d]pyrimidin-7-yl)-nonan-2-o...)copy SMILEScopy InChI
Affinity DataKi:  1.80E+5nMAssay Description:Inhibition constant (Ki) against Human erythrocyte adenosine deaminaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X067M7PubMed
TargetAdenosine deaminase(Bos taurus (bovine))
Universit£ di Camerino

Curated by ChEMBL
LigandPNGBDBM50011566(3-(4-Amino-pyrrolo[2,3-d]pyrimidin-7-yl)-nonan-2-o...)copy SMILEScopy InChI
Affinity DataKi:  4.00E+5nMAssay Description:Inhibition constant (Ki) against calf intestine adenosine deaminaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X067M7PubMed
TargetGTPase HRas(Homo sapiens (Human))
Universit£ di Ferrara

Curated by ChEMBL
LigandPNGBDBM50089969(5-[Bis-(2-chloro-ethyl)-amino]-benzofuran-2-carbox...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) productsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959J79PubMed
TargetGTPase HRas(Homo sapiens (Human))
Universit£ di Ferrara

Curated by ChEMBL
LigandPNGBDBM50089961(5-{4-[Bis-(2-chloro-ethyl)-amino]-benzoylamino}-1-...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) productsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959J79PubMed
TargetGTPase HRas(Homo sapiens (Human))
Universit£ di Ferrara

Curated by ChEMBL
LigandPNGBDBM50089960(5-{4-[Bis-(2-chloro-ethyl)-amino]-benzoylamino}-1H...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) productsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959J79PubMed
TargetGTPase HRas(Homo sapiens (Human))
Universit£ di Ferrara

Curated by ChEMBL
LigandPNGBDBM50089967(5-{4-[Bis-(2-chloro-ethyl)-amino]-benzoylamino}-1H...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) productsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959J79PubMed
TargetGTPase HRas(Homo sapiens (Human))
Universit£ di Ferrara

Curated by ChEMBL
LigandPNGBDBM50089962(5-{4-[Bis-(2-chloro-ethyl)-amino]-benzoylamino}-be...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) productsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959J79PubMed
TargetGTPase HRas(Homo sapiens (Human))
Universit£ di Ferrara

Curated by ChEMBL
LigandPNGBDBM50089978(5-[Bis-(2-chloro-ethyl)-amino]-1H-indole-2-carboxy...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) productsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959J79PubMed
TargetGTPase HRas(Homo sapiens (Human))
Universit£ di Ferrara

Curated by ChEMBL
LigandPNGBDBM50089971(5-[Bis-(2-chloro-ethyl)-amino]-1-methyl-1H-indole-...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) productsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959J79PubMed
TargetGTPase HRas(Homo sapiens (Human))
Universit£ di Ferrara

Curated by ChEMBL
LigandPNGBDBM50055659(2N-(3,3-aminoiminopropyl)-4-[4-(4-formamido-1-meth...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) productsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959J79PubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50008936((S)-10-Amino-4-ethyl-4-hydroxy-1,12-dihydro-4H-2-o...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMAssay Description:Concentration required to inhibit 50% relaxation of 250 ng of SV40 DNA obtained with 0.5 I.U topoisomerase I at 37 degrees C for 30 minMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43T3V
TargetDNA topoisomerase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291417((E)-3-((S)-4-Ethyl-4-hydroxy-3,13-dioxo-3,4,12,13-...)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+3nMAssay Description:Concentration required to inhibit 50% relaxation of 250 ng of SV40 DNA obtained with 0.5 I.U topoisomerase I at 37 degrees C for 30 minMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43T3V
TargetDNA topoisomerase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291415((S)-4-Ethyl-4-hydroxy-10-vinyl-1,12-dihydro-4H-2-o...)copy SMILEScopy InChI
Affinity DataIC50: 4.20E+3nMAssay Description:Concentration required to inhibit 50% relaxation of 250 ng of SV40 DNA obtained with 0.5 I.U topoisomerase I at 37 degrees C for 30 minMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43T3V
TargetDNA topoisomerase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291418((E)-3-((S)-4-Ethyl-4-hydroxy-3,13-dioxo-3,4,12,13-...)copy SMILEScopy InChI
Affinity DataIC50: 6.70E+3nMAssay Description:Concentration required to inhibit 50% relaxation of 250 ng of SV40 DNA obtained with 0.5 I.U topoisomerase I at 37 degrees C for 30 minMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43T3V
TargetDNA topoisomerase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291416(2-Acetylamino-3-((S)-4-ethyl-4-hydroxy-3,13-dioxo-...)copy SMILEScopy InChI
Affinity DataIC50: 1.13E+4nMAssay Description:Concentration required to inhibit 50% relaxation of 250 ng of SV40 DNA obtained with 0.5 I.U topoisomerase I at 37 degrees C for 30 minMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43T3V
TargetDNA topoisomerase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291412((Z)-2-Acetylamino-3-((S)-4-ethyl-4-hydroxy-3,13-di...)copy SMILEScopy InChI
Affinity DataIC50: 3.19E+4nMAssay Description:Concentration required to inhibit 50% relaxation of 250 ng of SV40 DNA obtained with 0.5 I.U topoisomerase I at 37 degrees C for 30 minMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43T3V
TargetDNA topoisomerase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291410(3-((S)-4-Ethyl-4-hydroxy-3,13-dioxo-3,4,12,13-tetr...)copy SMILEScopy InChI
Affinity DataIC50: 4.18E+4nMAssay Description:Concentration required to inhibit 50% relaxation of 250 ng of SV40 DNA obtained with 0.5 I.U topoisomerase I at 37 degrees C for 30 minMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43T3V
TargetDNA topoisomerase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291411((S)-4-Ethyl-4-hydroxy-10-((E)-styryl)-1,12-dihydro...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Concentration required to inhibit 50% relaxation of 250 ng of SV40 DNA obtained with 0.5 I.U topoisomerase I at 37 degrees C for 30 minMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43T3V
TargetDNA topoisomerase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291413((E)-3-((S)-4-Ethyl-4-hydroxy-3,13-dioxo-3,4,12,13-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Concentration required to inhibit 50% relaxation of 250 ng of SV40 DNA obtained with 0.5 I.U topoisomerase I at 37 degrees C for 30 minMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43T3V
TargetDNA topoisomerase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291414((S)-4-Ethyl-4-hydroxy-10-phenethyl-1,12-dihydro-4H...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Concentration required to inhibit 50% relaxation of 250 ng of SV40 DNA obtained with 0.5 I.U topoisomerase I at 37 degrees C for 30 minMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43T3V