Compile Data Set for Download or QSAR
Found 216 with Last Name = 'hedgecock' and Initial = 'c'
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054585((Z)-2-Cyano-3-cyclopropyl-3-hydroxy-N-(4-trifluoro...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KSXPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054573((Z)-2-Cyano-3-cyclopropyl-3-hydroxy-N-(4-trifluoro...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KSXPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054556((Z)-2-Cyano-3-cyclopropyl-3-hydroxy-N-(4-trifluoro...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KSXPubMed
TargetSignal peptidase I(Escherichia coli (strain K12))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50469157(CHEMBL4284736)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of Escherichia coli type 1 signal peptidase lepB preincubated for 10 mins followed by Dabcyl-VGGTATAYGAFSRPGLE-(EDANS)-OH substrate additi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70JH1PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054601(5-Methyl-N-(4-(trifluoromethyl)phenyl)-4-isoxazole...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KSXPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054541((Z)-2-Cyano-3-cyclopropyl-3-hydroxy-N-(3-methyl-4-...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KSXPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054590((Z)-2-Cyano-3-cyclopropyl-3-hydroxy-N-(3-methyl-4-...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KSXPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM14712((2Z)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)pheny...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054552((Z)-2-Cyano-3-cyclopropyl-3-hydroxy-N-(4-methylsul...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KSXPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054560((Z)-2-Cyano-3-cyclopropyl-3-hydroxy-N-(3-methyl-4-...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KSXPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054581((Z)-2-Cyano-3-cyclopropyl-3-hydroxy-N-(4-trifluoro...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KSXPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054597((Z)-2-Cyano-3-cyclopropyl-3-hydroxy-N-(5-trifluoro...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KSXPubMed
TargetSignal peptidase I(Escherichia coli (strain K12))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50469159(CHEMBL4283840)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of Escherichia coli type 1 signal peptidase lepB preincubated for 10 mins followed by Dabcyl-VGGTATAYGAFSRPGLE-(EDANS)-OH substrate additi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70JH1PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054574((Z)-2-Cyano-3-cyclopropyl-3-hydroxy-N-(3-methyl-4-...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KSXPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM29024(CHEMBL141732 | cyanocyclopropylpropenamide, 4)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KSXPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054557((Z)-2-Cyano-3-cyclopropyl-3-hydroxy-N-(4-nitro-phe...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KSXPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Mus musculus)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50407985(CHEMBL2111978)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibitory concentration tested on enzyme dihydroorotate dehydrogenase in mouseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KSXPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054600((Z)-2-Cyano-3-hydroxy-penta-2,4-dienoic acid (4-tr...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KSXPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054553((Z)-2-Cyano-N-(4-cyano-3-methyl-phenyl)-3-cyclopro...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KSXPubMed
TargetSignal peptidase I(Escherichia coli (strain K12))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50469154(CHEMBL4283678)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of Escherichia coli type 1 signal peptidase lepB preincubated for 10 mins followed by Dabcyl-VGGTATAYGAFSRPGLE-(EDANS)-OH substrate additi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70JH1PubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Homo sapiens (Human))
KANCERA AB

US Patent
LigandPNGBDBM200906(US9233946, 5)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Method A: The kinase activity of the bi-functional enzyme is readily quantified based on the production of F-2,6-P2 as described by Van Schaftingen e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123KBUS Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Mus musculus)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054601(5-Methyl-N-(4-(trifluoromethyl)phenyl)-4-isoxazole...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibitory concentration tested on enzyme dihydroorotate dehydrogenase in mouseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KSXPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054594((Z)-N-(4-Chloro-3-methyl-phenyl)-2-cyano-3-cyclopr...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KSXPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Mus musculus)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054584((Z)-N-(4-Chloro-phenyl)-2-cyano-3-cyclopropyl-3-hy...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibitory concentration tested on enzyme dihydroorotate dehydrogenase in mouseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KSXPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Mus musculus)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054548((Z)-N-(4-Bromo-phenyl)-2-cyano-3-cyclopropyl-3-hyd...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibitory concentration tested on enzyme dihydroorotate dehydrogenase in mouseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KSXPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Mus musculus)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054553((Z)-2-Cyano-N-(4-cyano-3-methyl-phenyl)-3-cyclopro...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibitory concentration tested on enzyme dihydroorotate dehydrogenase in mouseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KSXPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054549((Z)-N-(5-Bromo-pyridin-2-yl)-2-cyano-3-cyclopropyl...)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KSXPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Mus musculus)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054594((Z)-N-(4-Chloro-3-methyl-phenyl)-2-cyano-3-cyclopr...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibitory concentration tested on enzyme dihydroorotate dehydrogenase in mouseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KSXPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054564((Z)-2-Cyano-3-cyclopropyl-N-(3-ethyl-4-trifluorome...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KSXPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50407985(CHEMBL2111978)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KSXPubMed
TargetSignal peptidase I(Escherichia coli (strain K12))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50469162(CHEMBL4282733)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of Escherichia coli type 1 signal peptidase lepB preincubated for 10 mins followed by Dabcyl-VGGTATAYGAFSRPGLE-(EDANS)-OH substrate additi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70JH1PubMed
TargetSignal peptidase I(Escherichia coli (strain K12))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50469165(CHEMBL4291540)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of Escherichia coli type 1 signal peptidase lepB preincubated for 10 mins followed by Dabcyl-VGGTATAYGAFSRPGLE-(EDANS)-OH substrate additi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70JH1PubMed
TargetSignal peptidase I(Escherichia coli (strain K12))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50469170(CHEMBL4291025)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of Escherichia coli type 1 signal peptidase lepB preincubated for 10 mins followed by Dabcyl-VGGTATAYGAFSRPGLE-(EDANS)-OH substrate additi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70JH1PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Mus musculus)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054587((Z)-2-Cyano-N-(4-cyano-phenyl)-3-cyclopropyl-3-hyd...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibitory concentration tested on enzyme dihydroorotate dehydrogenase in mouseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KSXPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Mus musculus)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM29024(CHEMBL141732 | cyanocyclopropylpropenamide, 4)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Inhibitory concentration tested on enzyme dihydroorotate dehydrogenase in mouseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KSXPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Mus musculus)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054557((Z)-2-Cyano-3-cyclopropyl-3-hydroxy-N-(4-nitro-phe...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibitory concentration tested on enzyme dihydroorotate dehydrogenase in mouseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KSXPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054578((Z)-N-(4-Bromo-3-methyl-phenyl)-2-cyano-3-cyclopro...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KSXPubMed
TargetSignal peptidase I(Escherichia coli (strain K12))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50469166(CHEMBL4294422)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibition of Escherichia coli type 1 signal peptidase lepB preincubated for 10 mins followed by Dabcyl-VGGTATAYGAFSRPGLE-(EDANS)-OH substrate additi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70JH1PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054587((Z)-2-Cyano-N-(4-cyano-phenyl)-3-cyclopropyl-3-hyd...)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KSXPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Mus musculus)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054560((Z)-2-Cyano-3-cyclopropyl-3-hydroxy-N-(3-methyl-4-...)copy SMILEScopy InChI
Affinity DataIC50: 55nMAssay Description:Inhibitory concentration tested on enzyme dihydroorotate dehydrogenase in mouseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KSXPubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4(Homo sapiens (Human))
KANCERA AB

US Patent
LigandPNGBDBM200906(US9233946, 5)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Method B: The kinase activity of the bi-functional enzyme is readily quantified based on the production of ADP and F-2,6-P2 from ATP and F6P. The ADP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123KBUS Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Mus musculus)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054578((Z)-N-(4-Bromo-3-methyl-phenyl)-2-cyano-3-cyclopro...)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibitory concentration tested on enzyme dihydroorotate dehydrogenase in mouseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KSXPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Mus musculus)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054565((2Z,4E)-2-Cyano-3-hydroxy-hexa-2,4-dienoic acid (4...)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibitory concentration tested on enzyme dihydroorotate dehydrogenase in mouseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KSXPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054584((Z)-N-(4-Chloro-phenyl)-2-cyano-3-cyclopropyl-3-hy...)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KSXPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054606((Z)-N-(4-Acetyl-phenyl)-2-cyano-3-cyclopropyl-3-hy...)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KSXPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Mus musculus)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM14712((2Z)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)pheny...)copy SMILEScopy InChI
Affinity DataIC50: 69nMAssay Description:Inhibitory concentration tested on enzyme dihydroorotate dehydrogenase in mouseMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Mus musculus)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054564((Z)-2-Cyano-3-cyclopropyl-N-(3-ethyl-4-trifluorome...)copy SMILEScopy InChI
Affinity DataIC50: 71nMAssay Description:Inhibitory concentration tested on enzyme dihydroorotate dehydrogenase in mouseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KSXPubMed
TargetSignal peptidase I(Escherichia coli (strain K12))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50469169(CHEMBL4292925)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Inhibition of Escherichia coli type 1 signal peptidase lepB preincubated for 10 mins followed by Dabcyl-VGGTATAYGAFSRPGLE-(EDANS)-OH substrate additi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70JH1PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054555((Z)-N-(5-Chloro-pyridin-2-yl)-2-cyano-3-cyclopropy...)copy SMILEScopy InChI
Affinity DataIC50: 76nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KSXPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054591((Z)-N-(3-Chloro-4-methyl-phenyl)-2-cyano-3-cyclopr...)copy SMILEScopy InChI
Affinity DataIC50: 79nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KSXPubMed
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