TargetSerotonin 2 (5-HT2) receptor(RAT)
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Curated by ChEMBL
Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer
Curated by ChEMBL
Affinity DataKi: 0.260nMAssay Description:Binding constant against 5-hydroxytryptamine 2 receptor (in vivo)More data for this Ligand-Target Pair
TargetSerotonin 2 (5-HT2) receptor(RAT)
Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer
Curated by ChEMBL
Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer
Curated by ChEMBL
Affinity DataKi: 0.690nMAssay Description:Binding constant against 5-hydroxytryptamine 2 receptor (in vitro)More data for this Ligand-Target Pair
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer
Curated by ChEMBL
Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer
Curated by ChEMBL
Affinity DataKi: 6nMAssay Description:Binding constant against histamine H1 receptor (in vitro)More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer
Curated by ChEMBL
Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer
Curated by ChEMBL
Affinity DataKi: 22nMAssay Description:Binding constant against dopamine receptor D2 (in vitro)More data for this Ligand-Target Pair
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer
Curated by ChEMBL
Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer
Curated by ChEMBL
Affinity DataKi: 25nMAssay Description:Binding constant against histamine H1 receptor (in vivo)More data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer
Curated by ChEMBL
Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer
Curated by ChEMBL
Affinity DataKi: 29nMAssay Description:Binding constant against Alpha-1 adrenergic receptor (in vitro)More data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer
Curated by ChEMBL
Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer
Curated by ChEMBL
Affinity DataKi: 38nMAssay Description:Binding constant against Alpha-1 adrenergic receptor (in vivo)More data for this Ligand-Target Pair
Affinity DataKi: 68nMAssay Description:Mixed inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
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Curated by ChEMBL
Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer
Curated by ChEMBL
Affinity DataKi: 70nMAssay Description:Binding constant against 5-hydroxytryptamine 1A receptor (in vivo)More data for this Ligand-Target Pair
Affinity DataKi: 120nMAssay Description:Mixed type inhibition of porcine pancreatic lipase using 4MUO as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
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Curated by ChEMBL
Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Binding constant against dopamine receptor D2 (in vivo)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer
Curated by ChEMBL
Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer
Curated by ChEMBL
Affinity DataKi: 1.00E+3nMAssay Description:Binding constant against 5-hydroxytryptamine 1A receptor (in vitro)More data for this Ligand-Target Pair
Affinity DataKi: 1.50E+3nMAssay Description:Inhibition of human CES2A using 4-methylumbelliferone as a substrateMore data for this Ligand-Target Pair
TargetSerotonin 2 (5-HT2) receptor(RAT)
Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer
Curated by ChEMBL
Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:The concentration required to inhibit [3H]ketanserin binding to 5-hydroxytryptamine 2 receptor in rat brain membranes (in vitro)More data for this Ligand-Target Pair
TargetSerotonin 2 (5-HT2) receptor(RAT)
Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer
Curated by ChEMBL
Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:The concentration required to inhibit [3H]ketanserin binding to 5-hydroxytryptamine 2 receptor in rat brain membranes (in vitro)More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of PARP-2 (unknown origin) pre-incubated for 30 mins before addition of activated DNA and NAD by chemiluminescent assayMore data for this Ligand-Target Pair
TargetSerotonin 2 (5-HT2) receptor(RAT)
Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer
Curated by ChEMBL
Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:The concentration required to inhibit [3H]ketanserin binding to 5-hydroxytryptamine 2 receptor in rat brain membranes (in vitro)More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of PARP-2 (unknown origin) pre-incubated for 30 mins before addition of activated DNA and NAD by chemiluminescent assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of PARP-2 (unknown origin) pre-incubated for 30 mins before addition of activated DNA and NAD by chemiluminescent assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of PARP-2 (unknown origin) pre-incubated for 30 mins before addition of activated DNA and NAD by chemiluminescent assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of PARP-2 (unknown origin) pre-incubated for 30 mins before addition of activated DNA and NAD by chemiluminescent assayMore data for this Ligand-Target Pair
TargetSerotonin 2 (5-HT2) receptor(RAT)
Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer
Curated by ChEMBL
Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Binding constant against dopamine receptor D2 (in vivo)More data for this Ligand-Target Pair
TargetSerotonin 2 (5-HT2) receptor(RAT)
Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer
Curated by ChEMBL
Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:The concentration required to inhibit [3H]ketanserin binding to 5-hydroxytryptamine 2 receptor in rat brain membranes (in vitro)More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of PARP-2 (unknown origin) pre-incubated for 30 mins before addition of activated DNA and NAD by chemiluminescent assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of PARP-2 (unknown origin) pre-incubated for 30 mins before addition of activated DNA and NAD by chemiluminescent assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of PARP-2 (unknown origin) pre-incubated for 30 mins before addition of activated DNA and NAD by chemiluminescent assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibition of PARP-2 (unknown origin) pre-incubated for 30 mins before addition of activated DNA and NAD by chemiluminescent assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibition of PARP-2 (unknown origin) pre-incubated for 30 mins before addition of activated DNA and NAD by chemiluminescent assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibition of PARP-2 (unknown origin) pre-incubated for 30 mins before addition of activated DNA and NAD by chemiluminescent assayMore data for this Ligand-Target Pair
TargetSerotonin 2 (5-HT2) receptor(RAT)
Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer
Curated by ChEMBL
Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:The concentration required to inhibit [3H]ketanserin binding to 5-hydroxytryptamine 2 receptor in rat brain membranes (in vitro)More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of PARP-2 (unknown origin) pre-incubated for 30 mins before addition of activated DNA and NAD by chemiluminescent assayMore data for this Ligand-Target Pair
TargetSerotonin 2 (5-HT2) receptor(RAT)
Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer
Curated by ChEMBL
Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:The concentration required to inhibit [3H]ketanserin binding to 5-hydroxytryptamine 2 receptor in rat brain membranes (in vitro)More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of PARP-2 (unknown origin) pre-incubated for 30 mins before addition of activated DNA and NAD by chemiluminescent assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of PARP-2 (unknown origin) pre-incubated for 30 mins before addition of activated DNA and NAD by chemiluminescent assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human PARP-1 catalytic domain (662 to 1011 residues) expressed in Escherichia coli BL21(DE3) cells pre-incubated for 30 mins before add...More data for this Ligand-Target Pair
TargetSerotonin 2 (5-HT2) receptor(RAT)
Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer
Curated by ChEMBL
Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:The concentration required to inhibit [3H]ketanserin binding to 5-hydroxytryptamine 2 receptor in rat brain membranes (in vitro)More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of PARP-2 (unknown origin) pre-incubated for 30 mins before addition of activated DNA and NAD by chemiluminescent assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of PARP-2 (unknown origin) pre-incubated for 30 mins before addition of activated DNA and NAD by chemiluminescent assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Compound was tested for its binding affinity to NK1 receptor in [3H]-SP binding assay on rat brain membranes.More data for this Ligand-Target Pair
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