Compile Data Set for Download or QSAR
Found 143 with Last Name = 'krivacic' and Initial = 'c'
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50246967(CHEMBL4080228 | US10570121, Example 81)copy SMILEScopy InChI
Affinity DataKi: <0.100nMAssay Description:Binding affinity to EZH2 (unknown origin)More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50193709(CHEMBL3911017)copy SMILEScopy InChI
Affinity DataKi:  0.700nMAssay Description:Inhibition of wild-type EZH2 (unknown origin) expressed in baculovirus infected SF9 cells co-expressing SUZ12/EED/RbAp48 complex using HeLa cells der...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50193663(CHEMBL3929944)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibition of wild-type EZH2 (unknown origin) expressed in baculovirus infected SF9 cells co-expressing SUZ12/EED/RbAp48 complex using HeLa cells der...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J1053BPubMed
TargetHistone-lysine N-methyltransferase EZH1(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50246967(CHEMBL4080228 | US10570121, Example 81)copy SMILEScopy InChI
Affinity DataKi:  70nMAssay Description:Binding affinity to EZH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X069G8PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50193663(CHEMBL3929944)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of wild-type EZH2 (unknown origin) expressed in baculovirus infected SF9 cells co-expressing SUZ12/EED/RbAp48 complex using HeLa cells der...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J1053BPubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50246967(CHEMBL4080228 | US10570121, Example 81)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of EZH2 in human KARPAS422 cells assessed as reduction in H3K27me3 level after 72 hrs by ELISAMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50193708(CHEMBL3981606)copy SMILEScopy InChI
Affinity DataIC50: 5.60nMAssay Description:Inhibition of wild-type EZH2 (unknown origin) expressed in baculovirus infected SF9 cells co-expressing SUZ12/EED/RbAp48 complex using HeLa cells der...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J1053BPubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50246938(CHEMBL4082565)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of EZH2 in human KARPAS422 cells assessed as reduction in H3K27me3 level after 72 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X069G8PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50246962(CHEMBL4080043 | US10570121, Example 1)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of EZH2 in human KARPAS422 cells assessed as reduction in H3K27me3 level after 72 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X069G8PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50193709(CHEMBL3911017)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of EZH2 in human KARPAS422 cells assessed as reduction in H3K27Me3 levels after 72 hrs by ELISAMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50193712(CHEMBL3919969)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of wild-type EZH2 (unknown origin) expressed in baculovirus infected SF9 cells co-expressing SUZ12/EED/RbAp48 complex using HeLa cells der...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J1053BPubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50246927(CHEMBL4060447 | US10570121, Example 127)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of EZH2 in human KARPAS422 cells assessed as reduction in H3K27me3 level after 72 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X069G8PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50193709(CHEMBL3911017)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of EZH2 in human KARPAS422 cells assessed as reduction in H3K27me3 level after 72 hrs by ELISAMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50193724(CHEMBL3975589)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of wild-type EZH2 (unknown origin) expressed in baculovirus infected SF9 cells co-expressing SUZ12/EED/RbAp48 complex using HeLa cells der...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J1053BPubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50193656(CHEMBL3947760)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of wild-type EZH2 (unknown origin) expressed in baculovirus infected SF9 cells co-expressing SUZ12/EED/RbAp48 complex using HeLa cells der...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J1053BPubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50193706(CHEMBL3967105)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of wild-type EZH2 (unknown origin) expressed in baculovirus infected SF9 cells co-expressing SUZ12/EED/RbAp48 complex using HeLa cells der...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J1053BPubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50246968(CHEMBL4093757 | US10570121, Example 13)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of EZH2 in human KARPAS422 cells assessed as reduction in H3K27me3 level after 72 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X069G8PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50193660(CHEMBL3928387)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of wild-type EZH2 (unknown origin) expressed in baculovirus infected SF9 cells co-expressing SUZ12/EED/RbAp48 complex using HeLa cells der...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J1053BPubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50246952(CHEMBL4073054 | US10570121, Example 12)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of EZH2 in human KARPAS422 cells assessed as reduction in H3K27me3 level after 72 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X069G8PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50246942(CHEMBL4061264 | US10570121, Example 163)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Inhibition of EZH2 in human KARPAS422 cells assessed as reduction in H3K27me3 level after 72 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X069G8PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50193662(CHEMBL3911607)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of wild-type EZH2 (unknown origin) expressed in baculovirus infected SF9 cells co-expressing SUZ12/EED/RbAp48 complex using HeLa cells der...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J1053BPubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50193658(CHEMBL3946272)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of wild-type EZH2 (unknown origin) expressed in baculovirus infected SF9 cells co-expressing SUZ12/EED/RbAp48 complex using HeLa cells der...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J1053BPubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50246966(CHEMBL4061098 | US10570121, Example 16)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Inhibition of EZH2 in human KARPAS422 cells assessed as reduction in H3K27me3 level after 72 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X069G8PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50246966(CHEMBL4061098 | US10570121, Example 16)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Inhibition of EZH2 in human KARPAS422 cells assessed as reduction in H3K27me3 level after 72 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X069G8PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50246926(CHEMBL4062204 | US10570121, Example 82)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:Inhibition of EZH2 in human KARPAS422 cells assessed as reduction in H3K27me3 level after 72 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X069G8PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50246970(CHEMBL4060378)copy SMILEScopy InChI
Affinity DataIC50: 99nMAssay Description:Inhibition of EZH2 in human KARPAS422 cells assessed as reduction in H3K27me3 level after 72 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X069G8PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50193663(CHEMBL3929944)copy SMILEScopy InChI
Affinity DataIC50: 105nMAssay Description:Inhibition of EZH2 in human KARPAS422 cells assessed as reduction in H3K27Me3 levels after 72 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J1053BPubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50246927(CHEMBL4060447 | US10570121, Example 127)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of EZH2 in human KARPAS422 cells assessed as reduction in H3K27me3 level after 72 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X069G8PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50246964(CHEMBL4060640 | US10570121, Example 18)copy SMILEScopy InChI
Affinity DataIC50: 129nMAssay Description:Inhibition of EZH2 in human KARPAS422 cells assessed as reduction in H3K27me3 level after 72 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X069G8PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50193705(CHEMBL3947273)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of wild-type EZH2 (unknown origin) expressed in baculovirus infected SF9 cells co-expressing SUZ12/EED/RbAp48 complex using HeLa cells der...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J1053BPubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50193714(CHEMBL3984943)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of wild-type EZH2 (unknown origin) expressed in baculovirus infected SF9 cells co-expressing SUZ12/EED/RbAp48 complex using HeLa cells der...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J1053BPubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50193657(CHEMBL3955994)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of wild-type EZH2 (unknown origin) expressed in baculovirus infected SF9 cells co-expressing SUZ12/EED/RbAp48 complex using HeLa cells der...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J1053BPubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50193708(CHEMBL3981606)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of EZH2 in human KARPAS422 cells assessed as reduction in H3K27Me3 levels after 72 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J1053BPubMed
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50009672(AdoHcy | CHEMBL418052 | S-(5'-adenosyl)-L-homocyst...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of SMYD2 (unknown origin) by HMT assayMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EHMT1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50009672(AdoHcy | CHEMBL418052 | S-(5'-adenosyl)-L-homocyst...)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibition of EHMT1 (unknown origin) by HMT assayMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50246932(CHEMBL4073864 | US10570121, Example 112)copy SMILEScopy InChI
Affinity DataIC50: 231nMAssay Description:Inhibition of EZH2 in human KARPAS422 cells assessed as reduction in H3K27me3 level after 72 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X069G8PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50246932(CHEMBL4073864 | US10570121, Example 112)copy SMILEScopy InChI
Affinity DataIC50: 231nMAssay Description:Inhibition of EZH2 in human KARPAS422 cells assessed as reduction in H3K27me3 level after 72 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X069G8PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50246921(CHEMBL4077043)copy SMILEScopy InChI
Affinity DataIC50: 253nMAssay Description:Inhibition of EZH2 in human KARPAS422 cells assessed as reduction in H3K27me3 level after 72 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X069G8PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50246921(CHEMBL4077043)copy SMILEScopy InChI
Affinity DataIC50: 253nMAssay Description:Inhibition of EZH2 in human KARPAS422 cells assessed as reduction in H3K27me3 level after 72 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X069G8PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50063670(CHEMBL3397332)copy SMILES
Affinity DataIC50: 270nMAssay Description:Inhibition of N-terminally FLAG-tagged wild type EZH2 in EZH2/SUZ12/EED/RbAp48 complex (unknown origin) expressed in baculovirus infected in SF9 cell...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7CSSPubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50193724(CHEMBL3975589)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Inhibition of EZH2 in human KARPAS422 cells assessed as reduction in H3K27Me3 levels after 72 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J1053BPubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50193704(CHEMBL3973277)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibition of wild-type EZH2 (unknown origin) expressed in baculovirus infected SF9 cells co-expressing SUZ12/EED/RbAp48 complex using HeLa cells der...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J1053BPubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50246927(CHEMBL4060447 | US10570121, Example 127)copy SMILEScopy InChI
Affinity DataIC50: 391nMAssay Description:Inhibition of EZH2 in human KARPAS422 cells assessed as reduction in H3K27me3 level after 72 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X069G8PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50246927(CHEMBL4060447 | US10570121, Example 127)copy SMILEScopy InChI
Affinity DataIC50: 391nMAssay Description:Inhibition of EZH2 in human KARPAS422 cells assessed as reduction in H3K27me3 level after 72 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X069G8PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50246931(CHEMBL4065249 | US10570121, Example 117)copy SMILEScopy InChI
Affinity DataIC50: 430nMAssay Description:Inhibition of EZH2 in human KARPAS422 cells assessed as reduction in H3K27me3 level after 72 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X069G8PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50246931(CHEMBL4065249 | US10570121, Example 117)copy SMILEScopy InChI
Affinity DataIC50: 430nMAssay Description:Inhibition of EZH2 in human KARPAS422 cells assessed as reduction in H3K27me3 level after 72 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X069G8PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50246942(CHEMBL4061264 | US10570121, Example 163)copy SMILEScopy InChI
Affinity DataIC50: 494nMAssay Description:Inhibition of EZH2 in human KARPAS422 cells assessed as reduction in H3K27me3 level after 72 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X069G8PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50193712(CHEMBL3919969)copy SMILEScopy InChI
Affinity DataIC50: 502nMAssay Description:Inhibition of EZH2 in human KARPAS422 cells assessed as reduction in H3K27Me3 levels after 72 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J1053BPubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50193725(CHEMBL3956280)copy SMILEScopy InChI
Affinity DataIC50: 650nMAssay Description:Inhibition of wild-type EZH2 (unknown origin) expressed in baculovirus infected SF9 cells co-expressing SUZ12/EED/RbAp48 complex using HeLa cells der...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J1053BPubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
WuXi AppTec

Curated by ChEMBL
LigandPNGBDBM50246963(CHEMBL4072040 | US10570121, Example 30)copy SMILEScopy InChI
Affinity DataIC50: 682nMAssay Description:Inhibition of EZH2 in human KARPAS422 cells assessed as reduction in H3K27me3 level after 72 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X069G8PubMed
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