Compile Data Set for Download or QSAR
Found 354 with Last Name = 'panchal' and Initial = 'c'
TargetPolycomb protein EED(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50241660(CHEMBL4084398)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7D8GPubMed
TargetPolycomb protein EED(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50241662(CHEMBL4104741)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Binding affinity to GST tagged EED (unknown origin) after 1 hr by OG(488) probe based TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7D8GPubMed
TargetPolycomb protein EED(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM223987(A-395 (5) | rac-(3R,4S)-1-(7-fluoro-2,3-dihydro-1H...)copy SMILEScopy InChI
Affinity DataKi:  0.400nM ΔG°:  -53.6kJ/molepH: 7.5 T: 2°CAssay Description:For the assay, compounds were dispensed in assay-ready plates using a three-fold serial dilution from 50 μM to ~850 pM using an Echo 550 Acousti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4PGDPubMed
TargetPolycomb protein EED(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM223987(A-395 (5) | rac-(3R,4S)-1-(7-fluoro-2,3-dihydro-1H...)copy SMILEScopy InChI
Affinity DataKi:  0.5nM ΔG°:  -53.1kJ/molepH: 7.5 T: 2°CAssay Description:For the assay, compounds were dispensed in assay-ready plates using a three-fold serial dilution from 50 μM to ~850 pM using an Echo 550 Acousti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4PGDPubMed
TargetPolycomb protein EED(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50235631(CHEMBL4060827)copy SMILEScopy InChI
Affinity DataKi:  0.700nMAssay Description:Inhibition of ADP-induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7D8GPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50265666(CHEMBL4068431)copy SMILEScopy InChI
Affinity DataKi:  0.800nMAssay Description:Inhibition of human N-terminal His6-tagged BRD4 BD1-BD2 (57 to 550 residues) expressed in EScherichia coli BL21(DE3) after 1 hr by Alexa-647-conjugat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8VPNPubMed
TargetPolycomb protein EED(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM223986((3R,4S)-1-[(1S)-7-fluoroindan-1-yl]-N,N-dimethyl-4...)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Inhibition of ADP-induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPolycomb protein EED(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM223986((3R,4S)-1-[(1S)-7-fluoroindan-1-yl]-N,N-dimethyl-4...)copy SMILEScopy InChI
Affinity DataKi:  1nM ΔG°:  -51.4kJ/molepH: 7.5 T: 2°CAssay Description:For the assay, compounds were dispensed in assay-ready plates using a three-fold serial dilution from 50 μM to ~850 pM using an Echo 550 Acousti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetBromodomain-containing protein 4(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50265655(CHEMBL4099010)copy SMILEScopy InChI
Affinity DataKi:  1.5nMAssay Description:Inhibition of human N-terminal His6-tagged BRD4 BD1-BD2 (57 to 550 residues) expressed in EScherichia coli BL21(DE3) after 1 hr by Alexa-647-conjugat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8VPNPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50265637(CHEMBL4073279)copy SMILEScopy InChI
Affinity DataKi:  1.5nMAssay Description:Inhibition of human N-terminal His6-tagged BRD4 BD1-BD2 (57 to 550 residues) expressed in EScherichia coli BL21(DE3) after 1 hr by Alexa-647-conjugat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8VPNPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50265636(CHEMBL4090068)copy SMILEScopy InChI
Affinity DataKi:  1.90nMAssay Description:Inhibition of human N-terminal His6-tagged BRD4 BD1-BD2 (57 to 550 residues) expressed in EScherichia coli BL21(DE3) after 1 hr by Alexa-647-conjugat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8VPNPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50260099(CHEMBL4075567)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibition of human N-terminal His6-tagged BRD4 BD1-BD2 (57 to 550 residues) expressed in EScherichia coli BL21(DE3) after 1 hr by Alexa-647-conjugat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8VPNPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50265623(CHEMBL4091597)copy SMILEScopy InChI
Affinity DataKi:  2.60nMAssay Description:Inhibition of human N-terminal His6-tagged BRD4 BD1-BD2 (57 to 550 residues) expressed in EScherichia coli BL21(DE3) after 1 hr by Alexa-647-conjugat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8VPNPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50265653(CHEMBL4094644)copy SMILEScopy InChI
Affinity DataKi:  2.80nMAssay Description:Inhibition of human N-terminal His6-tagged BRD4 BD1-BD2 (57 to 550 residues) expressed in EScherichia coli BL21(DE3) after 1 hr by Alexa-647-conjugat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8VPNPubMed
TargetPolycomb protein EED(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50241646(CHEMBL4102320)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Inhibition of ADP-induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7D8GPubMed
TargetPolycomb protein EED(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50241655(CHEMBL4071358)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Binding affinity to GST tagged EED (unknown origin) after 1 hr by OG(488) probe based TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7D8GPubMed
TargetPolycomb protein EED(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50235648(CHEMBL4081496)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7D8GPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50265657(CHEMBL4075776)copy SMILEScopy InChI
Affinity DataKi:  3.40nMAssay Description:Inhibition of human N-terminal His6-tagged BRD4 BD1-BD2 (57 to 550 residues) expressed in EScherichia coli BL21(DE3) after 1 hr by Alexa-647-conjugat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8VPNPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50265659(CHEMBL4089651)copy SMILEScopy InChI
Affinity DataKi:  3.80nMAssay Description:Inhibition of human N-terminal His6-tagged BRD4 BD1-BD2 (57 to 550 residues) expressed in EScherichia coli BL21(DE3) after 1 hr by Alexa-647-conjugat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8VPNPubMed
TargetPolycomb protein EED(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM223985(rac-(3R,4S)-1-(2-fluoro-6-methylbenzyl)-N,N-dimeth...)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Binding affinity to GST tagged EED (unknown origin) after 1 hr by OG(488) probe based TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7D8GPubMed
TargetPolycomb protein EED(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM223985(rac-(3R,4S)-1-(2-fluoro-6-methylbenzyl)-N,N-dimeth...)copy SMILEScopy InChI
Affinity DataKi:  4nM ΔG°:  -47.9kJ/molepH: 7.5 T: 2°CAssay Description:For the assay, compounds were dispensed in assay-ready plates using a three-fold serial dilution from 50 μM to ~850 pM using an Echo 550 Acousti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4PGDPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50265662(CHEMBL4078875)copy SMILEScopy InChI
Affinity DataKi:  4.40nMAssay Description:Inhibition of human N-terminal His6-tagged BRD4 BD1-BD2 (57 to 550 residues) expressed in EScherichia coli BL21(DE3) after 1 hr by Alexa-647-conjugat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8VPNPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50265625(CHEMBL4082889)copy SMILEScopy InChI
Affinity DataKi:  5.10nMAssay Description:Inhibition of human N-terminal His6-tagged BRD4 BD1-BD2 (57 to 550 residues) expressed in EScherichia coli BL21(DE3) after 1 hr by Alexa-647-conjugat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8VPNPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50256398(CHEMBL4064089)copy SMILEScopy InChI
Affinity DataKi:  5.5nMAssay Description:Binding affinity to His-tagged BRD4 BD1-BD2 (K57 to K550 residues) (unknown origin) after 1 hr by Alexa-647-conjugated probe based TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P12FJPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50265663(CHEMBL4083819)copy SMILEScopy InChI
Affinity DataKi:  5.5nMAssay Description:Inhibition of human N-terminal His6-tagged BRD4 BD1-BD2 (57 to 550 residues) expressed in EScherichia coli BL21(DE3) after 1 hr by Alexa-647-conjugat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8VPNPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50265622(CHEMBL4063808)copy SMILEScopy InChI
Affinity DataKi:  5.60nMAssay Description:Inhibition of human N-terminal His6-tagged BRD4 BD1-BD2 (57 to 550 residues) expressed in EScherichia coli BL21(DE3) after 1 hr by Alexa-647-conjugat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8VPNPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50265629(CHEMBL4102713)copy SMILEScopy InChI
Affinity DataKi:  7nMAssay Description:Inhibition of human N-terminal His6-tagged BRD4 BD1-BD2 (57 to 550 residues) expressed in EScherichia coli BL21(DE3) after 1 hr by Alexa-647-conjugat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8VPNPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50265635(CHEMBL4068991)copy SMILEScopy InChI
Affinity DataKi:  7.30nMAssay Description:Inhibition of human N-terminal His6-tagged BRD4 BD1-BD2 (57 to 550 residues) expressed in EScherichia coli BL21(DE3) after 1 hr by Alexa-647-conjugat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8VPNPubMed
TargetPolycomb protein EED(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50241650(CHEMBL4100850)copy SMILEScopy InChI
Affinity DataKi:  8nMAssay Description:Inhibition of ADP-induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7D8GPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50265661(CHEMBL4103153)copy SMILEScopy InChI
Affinity DataKi:  8.20nMAssay Description:Inhibition of human N-terminal His6-tagged BRD4 BD1-BD2 (57 to 550 residues) expressed in EScherichia coli BL21(DE3) after 1 hr by Alexa-647-conjugat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8VPNPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50265671(CHEMBL4059680)copy SMILEScopy InChI
Affinity DataKi:  8.70nMAssay Description:Inhibition of human N-terminal His6-tagged BRD4 BD1-BD2 (57 to 550 residues) expressed in EScherichia coli BL21(DE3) after 1 hr by Alexa-647-conjugat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8VPNPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50265656(CHEMBL4075757)copy SMILEScopy InChI
Affinity DataKi:  8.90nMAssay Description:Inhibition of human N-terminal His6-tagged BRD4 BD1-BD2 (57 to 550 residues) expressed in EScherichia coli BL21(DE3) after 1 hr by Alexa-647-conjugat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8VPNPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50265665(CHEMBL4083186)copy SMILEScopy InChI
Affinity DataKi:  9nMAssay Description:Inhibition of human N-terminal His6-tagged BRD4 BD1-BD2 (57 to 550 residues) expressed in EScherichia coli BL21(DE3) after 1 hr by Alexa-647-conjugat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8VPNPubMed
TargetPolycomb protein EED(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50235626(CHEMBL4075197)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Binding affinity to GST tagged EED (unknown origin) after 1 hr by OG(488) probe based TR-FRET assayMore data for this Ligand-Target Pair
TargetPolycomb protein EED(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50241648(CHEMBL4072980)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Inhibition of ADP-induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7D8GPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50256359(CHEMBL4064625)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Binding affinity to His-tagged BRD4 BD1-BD2 (K57 to K550 residues) (unknown origin) after 1 hr by Alexa-647-conjugated probe based TR-FRET assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50265658(CHEMBL4077124)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:Inhibition of human N-terminal His6-tagged BRD4 BD1-BD2 (57 to 550 residues) expressed in EScherichia coli BL21(DE3) after 1 hr by Alexa-647-conjugat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8VPNPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50256354(CHEMBL4097720)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:Binding affinity to His-tagged BRD4 BD1-BD2 (K57 to K550 residues) (unknown origin) after 1 hr by Alexa-647-conjugated probe based TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P12FJPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50256402(CHEMBL4096183)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:Binding affinity to His-tagged BRD4 BD1-BD2 (K57 to K550 residues) (unknown origin) after 1 hr by Alexa-647-conjugated probe based TR-FRET assayMore data for this Ligand-Target Pair
TargetPolycomb protein EED(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50241645(CHEMBL4078052)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:Inhibition of ADP-induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7D8GPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50265627(CHEMBL4099335)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Inhibition of human N-terminal His6-tagged BRD4 BD1-BD2 (57 to 550 residues) expressed in EScherichia coli BL21(DE3) after 1 hr by Alexa-647-conjugat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8VPNPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50265633(CHEMBL4071697)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Inhibition of human N-terminal His6-tagged BRD4 BD1-BD2 (57 to 550 residues) expressed in EScherichia coli BL21(DE3) after 1 hr by Alexa-647-conjugat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8VPNPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50265632(CHEMBL4093439)copy SMILEScopy InChI
Affinity DataKi:  14nMAssay Description:Inhibition of human N-terminal His6-tagged BRD4 BD1-BD2 (57 to 550 residues) expressed in EScherichia coli BL21(DE3) after 1 hr by Alexa-647-conjugat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8VPNPubMed
TargetBromodomain-containing protein 2(Homo sapiens (Human))
AbbVie Inc., Oncology Discovery, 1 North Waukegan Rd., North Chicago, IL 60064, USA.

Curated by ChEMBL
LigandPNGBDBM342597(N-[3-(3-methyl-4-oxo-4,5,6,7-tetrahydro-2H-isoindo...)copy SMILEScopy InChI
Affinity DataKi:  14nMAssay Description:Binding affinity to BRD2 BD1-BD2 (G73 to A560 residues) (unknown origin) after 1 hr by Alexa-647-conjugated probe based TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P12FJPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50265624(CHEMBL4101823)copy SMILEScopy InChI
Affinity DataKi:  16nMAssay Description:Inhibition of human N-terminal His6-tagged BRD4 BD1-BD2 (57 to 550 residues) expressed in EScherichia coli BL21(DE3) after 1 hr by Alexa-647-conjugat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8VPNPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50256372(CHEMBL4074813)copy SMILEScopy InChI
Affinity DataKi:  16nMAssay Description:Binding affinity to His-tagged BRD4 BD1-BD2 (K57 to K550 residues) (unknown origin) after 1 hr by Alexa-647-conjugated probe based TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P12FJPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50265626(CHEMBL4061006)copy SMILEScopy InChI
Affinity DataKi:  17nMAssay Description:Inhibition of human N-terminal His6-tagged BRD4 BD1-BD2 (57 to 550 residues) expressed in EScherichia coli BL21(DE3) after 1 hr by Alexa-647-conjugat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8VPNPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM179283(US9125915, compound 6)copy SMILEScopy InChI
Affinity DataKi:  17nMAssay Description:Binding affinity to His-tagged BRD4 BD1-BD2 (K57 to K550 residues) (unknown origin) after 1 hr by Alexa-647-conjugated probe based TR-FRET assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM179283(US9125915, compound 6)copy SMILEScopy InChI
Affinity DataKi:  17nMAssay Description:Inhibition of human N-terminal His6-tagged BRD4 BD1-BD2 (57 to 550 residues) expressed in EScherichia coli BL21(DE3) after 1 hr by Alexa-647-conjugat...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50256406(CHEMBL4079684)copy SMILEScopy InChI
Affinity DataKi:  17nMAssay Description:Binding affinity to His-tagged BRD4 BD1-BD2 (K57 to K550 residues) (unknown origin) after 1 hr by Alexa-647-conjugated probe based TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P12FJPubMed
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