Compile Data Set for Download or QSAR
Found 62 with Last Name = 'pawlyn' and Initial = 'c'
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM191598(2-(((2-((2-(dimethylamino)ethyl)(ethyl)amino)-2-ox...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM191598(2-(((2-((2-(dimethylamino)ethyl)(ethyl)amino)-2-ox...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM191598(2-(((2-((2-(dimethylamino)ethyl)(ethyl)amino)-2-ox...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM223320(KDOAM-25)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5D(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM191598(2-(((2-((2-(dimethylamino)ethyl)(ethyl)amino)-2-ox...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM223320(KDOAM-25)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM191598(2-(((2-((2-(dimethylamino)ethyl)(ethyl)amino)-2-ox...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM191599(KDOAM-21 | ethyl 2-(((2-((2-(dimethylamino)ethyl)(...)copy SMILEScopy InChI
Affinity DataIC50: 49nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM191599(KDOAM-21 | ethyl 2-(((2-((2-(dimethylamino)ethyl)(...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 5D(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM223320(KDOAM-25)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM191599(KDOAM-21 | ethyl 2-(((2-((2-(dimethylamino)ethyl)(...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM223320(KDOAM-25)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM223320(KDOAM-25)copy SMILEScopy InChI
Affinity DataIC50: 69nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 5D(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM223320(KDOAM-25)copy SMILEScopy InChI
Affinity DataIC50: 69nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM223320(KDOAM-25)copy SMILEScopy InChI
Affinity DataIC50: 71nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM223320(KDOAM-25)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM223318(KDOAM-28)copy SMILEScopy InChI
Affinity DataIC50: 98nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 5D(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM191599(KDOAM-21 | ethyl 2-(((2-((2-(dimethylamino)ethyl)(...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM223318(KDOAM-28)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM191598(2-(((2-((2-(dimethylamino)ethyl)(ethyl)amino)-2-ox...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM191599(KDOAM-21 | ethyl 2-(((2-((2-(dimethylamino)ethyl)(...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 5D(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM223318(KDOAM-28)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM223318(KDOAM-28)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM191598(2-(((2-((2-(dimethylamino)ethyl)(ethyl)amino)-2-ox...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM223319(KDOAM-29)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM223318(KDOAM-28)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM223319(KDOAM-29)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM223319(KDOAM-29)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM191598(2-(((2-((2-(dimethylamino)ethyl)(ethyl)amino)-2-ox...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM223319(KDOAM-29)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM223317(KDOAM-1)copy SMILEScopy InChI
Affinity DataIC50: 980nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM223317(KDOAM-1)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM223317(KDOAM-1)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 5D(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM223319(KDOAM-29)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 3A(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM191598(2-(((2-((2-(dimethylamino)ethyl)(ethyl)amino)-2-ox...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM191598(2-(((2-((2-(dimethylamino)ethyl)(ethyl)amino)-2-ox...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM223317(KDOAM-1)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 2A(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM191598(2-(((2-((2-(dimethylamino)ethyl)(ethyl)amino)-2-ox...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM191599(KDOAM-21 | ethyl 2-(((2-((2-(dimethylamino)ethyl)(...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM191599(KDOAM-21 | ethyl 2-(((2-((2-(dimethylamino)ethyl)(...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 3A(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM191599(KDOAM-21 | ethyl 2-(((2-((2-(dimethylamino)ethyl)(...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM223320(KDOAM-25)copy SMILEScopy InChI
Affinity DataIC50: 4.80E+3nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM223320(KDOAM-25)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM223318(KDOAM-28)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM223320(KDOAM-25)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 4E(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM223317(KDOAM-1)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetHistone lysine demethylase PHF8(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM223320(KDOAM-25)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM191599(KDOAM-21 | ethyl 2-(((2-((2-(dimethylamino)ethyl)(...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM191599(KDOAM-21 | ethyl 2-(((2-((2-(dimethylamino)ethyl)(...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 2A(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM191599(KDOAM-21 | ethyl 2-(((2-((2-(dimethylamino)ethyl)(...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
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