Compile Data Set for Download or QSAR
Found 45 with Last Name = 'proffitt' and Initial = 'c'
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384714(CHEMBL2037200)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Reversible inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92CBWPubMed
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant CK2alpha by radiometric assayMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant CK2alpha at enzyme-substrate complex by radiometric assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384706(CHEMBL2037204)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92CBWPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384715(CHEMBL2037201)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92CBWPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384714(CHEMBL2037200)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92CBWPubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384706(CHEMBL2037204)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92CBWPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50335639(7-((1H-tetrazol-5-yl)methyl)indolo[1,2-a]quinazoli...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of PARP1 at 1 uM by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67H7NPubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384714(CHEMBL2037200)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of Pim3 using RSRHSSYPAGT as substrate by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92CBWPubMed
TargetDeath-associated protein kinase 3(Homo sapiens (Human))
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant DAPK3 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67H7NPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384717(CHEMBL2037203)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92CBWPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384709(CHEMBL2037195)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92CBWPubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384715(CHEMBL2037201)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92CBWPubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384714(CHEMBL2037200)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92CBWPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384713(CHEMBL2037199)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92CBWPubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of human recombinant TBK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67H7NPubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384718(CHEMBL2037205)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92CBWPubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384713(CHEMBL2037199)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92CBWPubMed
TargetDual specificity protein kinase CLK3(Homo sapiens (Human))
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of human recombinant CLK3 by radiometric assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384708(CHEMBL2037135)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92CBWPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384711(CHEMBL2037197)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92CBWPubMed
TargetHomeodomain-interacting protein kinase 3(Homo sapiens (Human))
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of human recombinant HIPK3 by radiometric assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of human recombinant PIM1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67H7NPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)copy SMILEScopy InChI
Affinity DataIC50: 55nMAssay Description:Inhibition of human recombinant FLT3 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67H7NPubMed
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of human recombinant CDK1/Cyclin B by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67H7NPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384718(CHEMBL2037205)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92CBWPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50335641(4-Oxo-4,5-dihydrothieno[3,2-c]quinoline-7-carboxam...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of PARP1 by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67H7NPubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384709(CHEMBL2037195)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92CBWPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384716(CHEMBL2037202)copy SMILEScopy InChI
Affinity DataIC50: 67nMAssay Description:Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92CBWPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384710(CHEMBL2037196)copy SMILEScopy InChI
Affinity DataIC50: 74.4nMAssay Description:Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92CBWPubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384719(CHEMBL2037206)copy SMILEScopy InChI
Affinity DataIC50: 82nMAssay Description:Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92CBWPubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384712(CHEMBL2037198)copy SMILEScopy InChI
Affinity DataIC50: 109nMAssay Description:Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92CBWPubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384710(CHEMBL2037196)copy SMILEScopy InChI
Affinity DataIC50: 127nMAssay Description:Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92CBWPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384719(CHEMBL2037206)copy SMILEScopy InChI
Affinity DataIC50: 131nMAssay Description:Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92CBWPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50384714(CHEMBL2037200)copy SMILEScopy InChI
Affinity DataIC50: 134nMAssay Description:Inhibition of Flt3 using EAIYAAPFAKKK as substrate by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92CBWPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50384715(CHEMBL2037201)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of Flt3 using EAIYAAPFAKKK as substrate by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92CBWPubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384717(CHEMBL2037203)copy SMILEScopy InChI
Affinity DataIC50: 217nMAssay Description:Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92CBWPubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384716(CHEMBL2037202)copy SMILEScopy InChI
Affinity DataIC50: 225nMAssay Description:Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92CBWPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384707(CHEMBL2037133)copy SMILEScopy InChI
Affinity DataIC50: 386nMAssay Description:Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92CBWPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50335642(7-(Hydroxymethyl)thieno[3,2-c]quinolin-4(5H)-one |...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of PARP1 by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67H7NPubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384711(CHEMBL2037197)copy SMILEScopy InChI
Affinity DataIC50: 445nMAssay Description:Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92CBWPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384712(CHEMBL2037198)copy SMILEScopy InChI
Affinity DataIC50: 506nMAssay Description:Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92CBWPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50335640(4-Oxo-4,5-dihydrothieno[3,2-c]quinoline-7-carboxyl...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibition of PARP1 by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67H7NPubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384715(CHEMBL2037201)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Pim3 using RSRHSSYPAGT as substrate by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92CBWPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50384714(CHEMBL2037200)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Flt3 phosphorylation at Y591 in human MV411 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92CBWPubMed