Compile Data Set for Download or QSAR
Found 214 with Last Name = 'scherer' and Initial = 'c'
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8891(3-(6-Methoxy-3,4-dihydronaphthalen-2-yl)pyridine |...)copy SMILEScopy InChI
Affinity DataKi:  1.30nM IC50: 2nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2FBSPubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8890(3-(5-Methoxy-1H-inden-2-yl)pyridine | indene 3)copy SMILEScopy InChI
Affinity DataKi:  2.60nM IC50: 4nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2FBSPubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8889(3-(3,4-Dihydronaphthalen-2-yl)pyridine | Dihydrona...)copy SMILEScopy InChI
Affinity DataKi:  4.60nM IC50: 7nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2FBSPubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8888(3-(1H-Inden-2-yl)pyridine | US9271963, 32 | indene...)copy SMILEScopy InChI
Affinity DataKi:  8.40nM IC50: 13nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2FBSPubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8909(6-(pyridin-3-yl)naphthalene-2-carbonitrile | 6-Pyr...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41PNTPubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50180899(CHEMBL201138 | {4-[4-(4-bromophenoxy)benzoyl]pheny...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Displacement of [3H]-[1beta,2beta]-testosterone from 5alpha reductase2 in human prostrate homogenateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ3285PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8894(3-(3-Methyl-3,4-dihydronaphthalen-2-yl)pyridine | ...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2FBSPubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8905(3-(6-Methoxy-2-naphthyl)pyridine | 3-(6-methoxynap...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41PNTPubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8892(3-(1-Methyl-3,4-dihydronaphthalen-2-yl)-pyridine |...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2FBSPubMed
TargetSerine/threonine-protein kinase 33(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400690(CHEMBL2203524)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant STK33 using myelin basic protein as substrate incubated for 15 mins before initiat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0H9XPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)copy SMILEScopy InChI
Affinity DataIC50: 10nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50121975((6-Methoxy-quinolin-4-yl)-(5-vinyl-1-aza-bicyclo[2...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 33(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400689(CHEMBL2203525)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant STK33 using myelin basic protein as substrate incubated for 15 mins before initiat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0H9XPubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8908(3-(6-Ethoxy-2-naphthyl)pyridine | 3-(6-ethoxynapht...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41PNTPubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8932(1-Methyl-5-(2-naphthyl)-1H-imidazole | 1-methyl-5-...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41PNTPubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8895(3-(4-Methyl-3,4-dihydronaphthalen-2-yl)pyridine | ...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2FBSPubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8910(3-(5-Chloro-6-methoxy-2-naphthyl)pyridine | 3-(5-c...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41PNTPubMed
TargetSerine/threonine-protein kinase 33(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400664(CHEMBL2204239)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant STK33 using myelin basic protein as substrate incubated for 15 mins before initiat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0H9XPubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8907(3-(6-Bromo-2-naphthyl)pyridine | 3-(6-bromonaphtha...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41PNTPubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8917(1-(3-methoxynaphthalen-2-yl)-1H-imidazole | Imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41PNTPubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50180895(4-(4-phenoxybenzoyl)phenylacetic acid | CHEMBL3700...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Displacement of [3H]-[1beta,2beta]-testosterone from 5alpha reductase2 in human prostrate homogenateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ3285PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8906(6-(pyridin-3-yl)naphthalen-2-ol | 6-Pyridin-3-ylna...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41PNTPubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8913(3-(1-Chloro-7-methoxy-2-naphthyl)pyridine | 3-(1-c...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41PNTPubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50180893((3-methyl-4-(4-phenoxybenzoyl)phenyl)acetic acid |...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Displacement of [3H]-[1beta,2beta]-testosterone from 5alpha reductase2 in human prostrate homogenateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ3285PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8904(3-(2-Naphthyl)pyridine | 3-(naphthalen-2-yl)pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41PNTPubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8912(3-(1,5-Dichloro-6-methoxy-2-naphthyl)pyridine | 3-...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41PNTPubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8913(3-(1-Chloro-7-methoxy-2-naphthyl)pyridine | 3-(1-c...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41PNTPubMed
TargetAromatase(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from 3H-labeled androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2FBSPubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8893(3-(1-Ethyl-3,4-dihydronaphthalen-2-yl)-pyridine | ...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2FBSPubMed
TargetAromatase(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41PNTPubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8911(3-(5-Bromo-6-methoxy-2-naphthyl)pyridine | 3-(5-br...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41PNTPubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8916(1-(2-Naphthyl)-1H-imidazole | 1-(naphthalen-2-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41PNTPubMed
TargetAromatase(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8610(1-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imi...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from 3H-labeled androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2FBSPubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8901(3-(7-Methoxy-3,4-dihydronaphthalen-2-yl)pyridine |...)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2FBSPubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50180898((3-fluoro-4-(4-phenoxybenzoyl)phenyl)acetic acid |...)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Displacement of [3H]-[1beta,2beta]-testosterone from 5alpha reductase2 in human prostrate homogenateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ3285PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50179201(((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihyd...)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibition of human placental 17beta-HSD1More data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50180894(4-(4-Phenoxy-benzoyl)-benzoic acid | 4-(4-phenoxyb...)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Displacement of [3H]-[1beta,2beta]-testosterone from 5alpha reductase2 in human prostrate homogenateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ3285PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8914(Methyl 6-pyridin-3-yl-2-naphthoate | Pyridine-subs...)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41PNTPubMed
TargetSerine/threonine-protein kinase 33(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400684(CHEMBL2203528)copy SMILEScopy InChI
Affinity DataIC50: 76nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant STK33 using myelin basic protein as substrate incubated for 15 mins before initiat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0H9XPubMed
TargetSerine/threonine-protein kinase 33(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400662(CHEMBL2204241)copy SMILEScopy InChI
Affinity DataIC50: 78nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant STK33 using myelin basic protein as substrate incubated for 15 mins before initiat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0H9XPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8917(1-(3-methoxynaphthalen-2-yl)-1H-imidazole | Imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 81nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41PNTPubMed
TargetSerine/threonine-protein kinase 33(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400665(CHEMBL2204238)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant STK33 using myelin basic protein as substrate incubated for 15 mins before initiat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0H9XPubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50180896(4-(4-{[2,5-bis(trifluoromethyl)benzyl]oxy}benzoyl)...)copy SMILEScopy InChI
Affinity DataIC50: 113nMAssay Description:Displacement of [3H]-[1beta,2beta]-testosterone from 5alpha reductase2 in human prostrate homogenateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ3285PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50168371(6-(3-Hydroxy-phenyl)-naphthalen-2-ol | 6-(3-hydrox...)copy SMILEScopy InChI
Affinity DataIC50: 116nMAssay Description:Inhibition of human placental 17beta-HSD1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5NPZPubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50180901(4-[4-benzyloxy)benzoyl]benzoic acid | CHEMBL202871)copy SMILEScopy InChI
Affinity DataIC50: 119nMAssay Description:Displacement of [3H]-[1beta,2beta]-testosterone from 5alpha reductase2 in human prostrate homogenateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ3285PubMed
TargetAromatase(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8917(1-(3-methoxynaphthalen-2-yl)-1H-imidazole | Imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 129nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41PNTPubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50180902(4-[3-(benzyloxy)benzoyl]benzoic acid | CHEMBL38264...)copy SMILEScopy InChI
Affinity DataIC50: 131nMAssay Description:Displacement of [3H]-[1beta,2beta]-testosterone from 5alpha reductase2 in human prostrate homogenateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ3285PubMed
TargetSerine/threonine-protein kinase 33(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400682(CHEMBL2203530)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant STK33 using myelin basic protein as substrate incubated for 15 mins before initiat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0H9XPubMed
TargetSerine/threonine-protein kinase 33(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400668(CHEMBL2204235)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant STK33 using myelin basic protein as substrate incubated for 15 mins before initiat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0H9XPubMed
TargetSerine/threonine-protein kinase 33(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400687(CHEMBL1992679)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant STK33 using myelin basic protein as substrate incubated for 15 mins before initiat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0H9XPubMed
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