Compile Data Set for Download or QSAR
Found 30 with Last Name = 'seira' and Initial = 'c'
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50317209((2R)-N-(adamantan-2-yl)-1-ethylpyrrolidine-2-carbo...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes assessed as conversion of [3H]-cortisone to [3H]-cortisol after 30 mins by scintillation proximit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5RVRPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50277203(CHEMBL4170932)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using [3H]cortisone as substrate preincubated for 15 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D5RPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50277198(CHEMBL4163698)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using [3H]cortisone as substrate preincubated for 15 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D5RPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50277197(CHEMBL4170544)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using [3H]cortisone as substrate preincubated for 15 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D5RPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50277179(CHEMBL4160328)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using [3H]cortisone as substrate preincubated for 15 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D5RPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50277178(CHEMBL4162610)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using [3H]cortisone as substrate preincubated for 15 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D5RPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50277199(CHEMBL4168636)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using [3H]cortisone as substrate preincubated for 15 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D5RPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50277206(CHEMBL4174155)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using [3H]cortisone as substrate preincubated for 15 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D5RPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50120378(CHEMBL3616709)copy SMILEScopy InChI
Affinity DataIC50: 74nMAssay Description:Inhibition of 11beta-HSD1 in human mixed sex human liver microsomes assessed as reduction in conversion of [3H]-cortisone to [3H]-cortisol pre-incuba...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP47Z5PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50277178(CHEMBL4162610)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of 11beta-HSD1 in CD1 mouse liver microsomes using cortisone as substrate preincubated for 15 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D5RPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50120377(CHEMBL1889797)copy SMILEScopy InChI
Affinity DataIC50: 86nMAssay Description:Inhibition of 11beta-HSD1 in human mixed sex human liver microsomes assessed as reduction in conversion of [3H]-cortisone to [3H]-cortisol pre-incuba...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP47Z5PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50277202(CHEMBL4174368)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using [3H]cortisone as substrate preincubated for 15 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D5RPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50317209((2R)-N-(adamantan-2-yl)-1-ethylpyrrolidine-2-carbo...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using [3H]cortisone as substrate preincubated for 15 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D5RPubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50277198(CHEMBL4163698)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of human full-length 11beta-HSD2 expressed in HEK293 cells using cortisol as substrate after 2 hrs by LC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D5RPubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50277202(CHEMBL4174368)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of human full-length 11beta-HSD2 expressed in HEK293 cells using cortisol as substrate after 2 hrs by LC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D5RPubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50277178(CHEMBL4162610)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of human full-length 11beta-HSD2 expressed in HEK293 cells using cortisol as substrate after 2 hrs by LC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D5RPubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50277203(CHEMBL4170932)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of human full-length 11beta-HSD2 expressed in HEK293 cells using cortisol as substrate after 2 hrs by LC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D5RPubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50277179(CHEMBL4160328)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of human full-length 11beta-HSD2 expressed in HEK293 cells using cortisol as substrate after 2 hrs by LC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D5RPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50277207(CHEMBL4172177)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using [3H]cortisone as substrate preincubated for 15 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D5RPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50277204(CHEMBL4160886)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using [3H]cortisone as substrate preincubated for 15 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D5RPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50499941(CHEMBL3740482)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes assessed as conversion of [3H]-cortisone to [3H]-cortisol after 30 mins by scintillation proximit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5RVRPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50277205(CHEMBL4166243)copy SMILEScopy InChI
Affinity DataIC50: 410nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using [3H]cortisone as substrate preincubated for 15 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D5RPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50120379(CHEMBL3616710)copy SMILEScopy InChI
Affinity DataIC50: 520nMAssay Description:Inhibition of 11beta-HSD1 in human mixed sex human liver microsomes assessed as reduction in conversion of [3H]-cortisone to [3H]-cortisol pre-incuba...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP47Z5PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50120376(CHEMBL596815)copy SMILEScopy InChI
Affinity DataIC50: 873nMAssay Description:Inhibition of 11beta-HSD1 in human mixed sex human liver microsomes assessed as reduction in conversion of [3H]-cortisone to [3H]-cortisol pre-incuba...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP47Z5PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50277197(CHEMBL4170544)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human full-length 11beta-HSD2 expressed in HEK293 cells using cortisol as substrate after 2 hrs by LC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D5RPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50499940(CHEMBL3740225)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes assessed as conversion of [3H]-cortisone to [3H]-cortisol after 30 mins by scintillation proximit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5RVRPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50277177(CHEMBL4164290)copy SMILEScopy InChI
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using [3H]cortisone as substrate preincubated for 15 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D5RPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50277208(CHEMBL4160714)copy SMILEScopy InChI
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using [3H]cortisone as substrate preincubated for 15 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D5RPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50277201(CHEMBL4167147)copy SMILEScopy InChI
Affinity DataIC50: 1.49E+3nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using [3H]cortisone as substrate preincubated for 15 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D5RPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50277200(CHEMBL4168826)copy SMILEScopy InChI
Affinity DataIC50: 2.77E+3nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using [3H]cortisone as substrate preincubated for 15 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D5RPubMed