Compile Data Set for Download or QSAR
Found 162 with Last Name = 'stresemann' and Initial = 'c'
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM50180955(CHEMBL3818617)copy SMILEScopy InChI
Affinity DataKi:  8nMAssay Description:Competitive inhibition of full length 6xHis-tagged SMYD2 (unknown origin) expressed in Escherichia coli using varying levels of Btn-Ahx-GSRAHSSHLKSKK...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN39S5PubMed
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM50180955(CHEMBL3818617)copy SMILEScopy InChI
Affinity DataKi:  28nMAssay Description:Uncompetitive inhibition of full length 6xHis-tagged SMYD2 (unknown origin) expressed in Escherichia coli using fixed levels of Btn-Ahx-GSRAHSSHLKSKK...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN39S5PubMed
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM283143((2R)—N-[1-{N′-cyano-N-[3-(difluorometho...)copy SMILEScopy InChI
Affinity DataIC50: 2.64nMAssay Description:For the detection of SMYD2 cellular methylation activity an In Cell Western (ICW) assay was established. This assay allows rapid processing of multip...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7RKDUS Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM283194(Rac-N-[1-(N′-cyano-N-{5-(difluoromethoxy)-2-...)copy SMILEScopy InChI
Affinity DataIC50: 5.55nMpH: 9.0Assay Description:SMYD2 inhibitory activities of the compounds described in the present invention were quantified using a scintillation proximity assay (SPA) which mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7RKDUS Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM283173(N-[1-{N′-cyano-N-[2-methoxy-5-(trifluorometh...)copy SMILEScopy InChI
Affinity DataIC50: 6.65nMpH: 9.0Assay Description:SMYD2 inhibitory activities of the compounds described in the present invention were quantified using a scintillation proximity assay (SPA) which mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7RKDUS Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM283196(Rac-N-[1-(N′-cyano-N-{2-[(1-methylpiperidin-...)copy SMILEScopy InChI
Affinity DataIC50: 9.09nMpH: 9.0Assay Description:SMYD2 inhibitory activities of the compounds described in the present invention were quantified using a scintillation proximity assay (SPA) which mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7RKDUS Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM283172(Rac-N-[1-{N′-cyano-N-[2-methoxy-5-(trifluoro...)copy SMILEScopy InChI
Affinity DataIC50: 9.98nMpH: 9.0Assay Description:SMYD2 inhibitory activities of the compounds described in the present invention were quantified using a scintillation proximity assay (SPA) which mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7RKDUS Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM50181506(CHEMBL3819038)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Antagonist activity at PAR1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN39S5PubMed
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM283169(Rac-N-[1-{N′-cyano-N-[5-(difluoromethoxy)-2-...)copy SMILEScopy InChI
Affinity DataIC50: 12.5nMpH: 9.0Assay Description:SMYD2 inhibitory activities of the compounds described in the present invention were quantified using a scintillation proximity assay (SPA) which mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7RKDUS Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM283143((2R)—N-[1-{N′-cyano-N-[3-(difluorometho...)copy SMILEScopy InChI
Affinity DataIC50: 13nMpH: 9.0Assay Description:SMYD2 inhibitory activities of the compounds described in the present invention were quantified using a scintillation proximity assay (SPA) which mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7RKDUS Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM283139(N-[1-{N′-cyano-N-[3-(difluoromethoxy)phenyl]...)copy SMILEScopy InChI
Affinity DataIC50: 13.2nMAssay Description:For the detection of SMYD2 cellular methylation activity an In Cell Western (ICW) assay was established. This assay allows rapid processing of multip...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7RKDUS Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM283139(N-[1-{N′-cyano-N-[3-(difluoromethoxy)phenyl]...)copy SMILEScopy InChI
Affinity DataIC50: 13.5nMpH: 9.0Assay Description:SMYD2 inhibitory activities of the compounds described in the present invention were quantified using a scintillation proximity assay (SPA) which mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7RKDUS Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM50075102(CHEMBL3414623)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of SMYD2 (unknown origin) expressed in Escherichia coli BL21 (DE3) using Biotinaminohexanoyl-GSRAHSSHLKSKKGQSTSRH as substrate after 75 mi...More data for this Ligand-Target Pair
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM283132(Rac-N-[1-{N′-cyano-N-[3-(difluoromethoxy)phe...)copy SMILEScopy InChI
Affinity DataIC50: 15nMpH: 9.0Assay Description:SMYD2 inhibitory activities of the compounds described in the present invention were quantified using a scintillation proximity assay (SPA) which mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7RKDUS Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM283195(Rac-N-[r-(N′-cyano-N-[2-[2-(pyrrolidin-1-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 15.8nMpH: 9.0Assay Description:SMYD2 inhibitory activities of the compounds described in the present invention were quantified using a scintillation proximity assay (SPA) which mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7RKDUS Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM50180967(CHEMBL3818487)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of SMYD2 (unknown origin) using H4 as substrate after 2hrs in presence 3H-SAM of by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN39S5PubMed
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM283184(N-[1-{N′-cyano-N-[3-(difluoromethoxy)-5-fluo...)copy SMILEScopy InChI
Affinity DataIC50: 19.2nMpH: 9.0Assay Description:SMYD2 inhibitory activities of the compounds described in the present invention were quantified using a scintillation proximity assay (SPA) which mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7RKDUS Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM283172(Rac-N-[1-{N′-cyano-N-[2-methoxy-5-(trifluoro...)copy SMILEScopy InChI
Affinity DataIC50: 21.3nMAssay Description:For the detection of SMYD2 cellular methylation activity an In Cell Western (ICW) assay was established. This assay allows rapid processing of multip...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7RKDUS Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM283205(N-[3-(4-Chloro-3-methylphenyl)-1-{N′-cyano-N...)copy SMILEScopy InChI
Affinity DataIC50: 22.9nMpH: 9.0Assay Description:SMYD2 inhibitory activities of the compounds described in the present invention were quantified using a scintillation proximity assay (SPA) which mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7RKDUS Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM283173(N-[1-{N′-cyano-N-[2-methoxy-5-(trifluorometh...)copy SMILEScopy InChI
Affinity DataIC50: 23.6nMAssay Description:For the detection of SMYD2 cellular methylation activity an In Cell Western (ICW) assay was established. This assay allows rapid processing of multip...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7RKDUS Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM283197(Rac-N-[1-(N′-cyano-N-{2-[(1-methylpiperidin-...)copy SMILEScopy InChI
Affinity DataIC50: 26.1nMpH: 9.0Assay Description:SMYD2 inhibitory activities of the compounds described in the present invention were quantified using a scintillation proximity assay (SPA) which mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7RKDUS Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM50180955(CHEMBL3818617)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of full length 6xHis-tagged SMYD2 (unknown origin) expressed in Escherichia coli using Btn-Ahx GSRAHSSHLKSKKGQSTSRH-amide as substrate aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN39S5PubMed
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM283169(Rac-N-[1-{N′-cyano-N-[5-(difluoromethoxy)-2-...)copy SMILEScopy InChI
Affinity DataIC50: 27.7nMAssay Description:For the detection of SMYD2 cellular methylation activity an In Cell Western (ICW) assay was established. This assay allows rapid processing of multip...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7RKDUS Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM50181508(CHEMBL3818083 | US10023539, Example 4.2)copy SMILEScopy InChI
Affinity DataIC50: 28.2nMpH: 9.0Assay Description:SMYD2 inhibitory activities of the compounds described in the present invention were quantified using a scintillation proximity assay (SPA) which mea...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7RKDUS Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM50181508(CHEMBL3818083 | US10023539, Example 4.2)copy SMILEScopy InChI
Affinity DataIC50: 28.2nMpH: 9.0Assay Description:SMYD2 inhibitory activities of the compounds described in the present invention were quantified using a scintillation proximity assay (SPA) which mea...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7RKDUS Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM283170(N-[1-{N′-cyano-N-[5-(difluoromethoxy)-2-meth...)copy SMILEScopy InChI
Affinity DataIC50: 28.7nMAssay Description:For the detection of SMYD2 cellular methylation activity an In Cell Western (ICW) assay was established. This assay allows rapid processing of multip...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7RKDUS Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM50181504(CHEMBL3818898)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Antagonist activity at PAR1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN39S5PubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM50181502(CHEMBL3818510)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Antagonist activity at PAR1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN39S5PubMed
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM283170(N-[1-{N′-cyano-N-[5-(difluoromethoxy)-2-meth...)copy SMILEScopy InChI
Affinity DataIC50: 30nMpH: 9.0Assay Description:SMYD2 inhibitory activities of the compounds described in the present invention were quantified using a scintillation proximity assay (SPA) which mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7RKDUS Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM283189(Rac-N-[1-{N′-cyano-N-[2-methoxy-5-(trifluoro...)copy SMILEScopy InChI
Affinity DataIC50: 30.6nMpH: 9.0Assay Description:SMYD2 inhibitory activities of the compounds described in the present invention were quantified using a scintillation proximity assay (SPA) which mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7RKDUS Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM283208(N-[1-{N′-cyano-N-[3-(difluoromethoxy)phenyl]...)copy SMILEScopy InChI
Affinity DataIC50: 32nMpH: 9.0Assay Description:SMYD2 inhibitory activities of the compounds described in the present invention were quantified using a scintillation proximity assay (SPA) which mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7RKDUS Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM283209(N-[1-{N′-cyano-N-[3-(difluoromethoxy)phenyl]...)copy SMILEScopy InChI
Affinity DataIC50: 35.6nMAssay Description:For the detection of SMYD2 cellular methylation activity an In Cell Western (ICW) assay was established. This assay allows rapid processing of multip...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7RKDUS Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM283208(N-[1-{N′-cyano-N-[3-(difluoromethoxy)phenyl]...)copy SMILEScopy InChI
Affinity DataIC50: 37.2nMAssay Description:For the detection of SMYD2 cellular methylation activity an In Cell Western (ICW) assay was established. This assay allows rapid processing of multip...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7RKDUS Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM283209(N-[1-{N′-cyano-N-[3-(difluoromethoxy)phenyl]...)copy SMILEScopy InChI
Affinity DataIC50: 37.5nMpH: 9.0Assay Description:SMYD2 inhibitory activities of the compounds described in the present invention were quantified using a scintillation proximity assay (SPA) which mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7RKDUS Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM50180974(CHEMBL3818092 | US10023539, Example 33.2)copy SMILEScopy InChI
Affinity DataIC50: 37.6nMpH: 9.0Assay Description:SMYD2 inhibitory activities of the compounds described in the present invention were quantified using a scintillation proximity assay (SPA) which mea...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7RKDUS Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM50180973(CHEMBL3819284)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of SMYD2 (unknown origin) using H4 as substrate after 2hrs in presence 3H-SAM of by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN39S5PubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM50181505(CHEMBL3819204)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Antagonist activity at PAR1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN39S5PubMed
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM283204(US10023539, Example 36 | rac-N-[3-(4-Chloro-3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 40.7nMpH: 9.0Assay Description:SMYD2 inhibitory activities of the compounds described in the present invention were quantified using a scintillation proximity assay (SPA) which mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7RKDUS Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM50180968(CHEMBL3818080)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of SMYD2 (unknown origin) using H4 as substrate after 2hrs in presence 3H-SAM of by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN39S5PubMed
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM283150(N-[1-{N-[4-chloro-3-(difluoromethoxy)phenyl]-NR...)copy SMILEScopy InChI
Affinity DataIC50: 44.1nMpH: 9.0Assay Description:SMYD2 inhibitory activities of the compounds described in the present invention were quantified using a scintillation proximity assay (SPA) which mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7RKDUS Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM50181508(CHEMBL3818083 | US10023539, Example 4.2)copy SMILEScopy InChI
Affinity DataIC50: 46.7nMAssay Description:For the detection of SMYD2 cellular methylation activity an In Cell Western (ICW) assay was established. This assay allows rapid processing of multip...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7RKDUS Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM283159(N-[1-{N′-cyano-N-[3-(trifluoromethoxy)phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 50nMpH: 9.0Assay Description:SMYD2 inhibitory activities of the compounds described in the present invention were quantified using a scintillation proximity assay (SPA) which mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7RKDUS Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM50181513(CHEMBL3819237)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Antagonist activity at PAR1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN39S5PubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM50181507(CHEMBL3818421)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Antagonist activity at PAR1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN39S5PubMed
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM50180971(CHEMBL3818322)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of SMYD2 (unknown origin) using H4 as substrate after 2hrs in presence 3H-SAM of by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN39S5PubMed
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM283179(N-[1-{N′-cyano-N-[3-(2,2,2-trifluoroethyl)ph...)copy SMILEScopy InChI
Affinity DataIC50: 53nMpH: 9.0Assay Description:SMYD2 inhibitory activities of the compounds described in the present invention were quantified using a scintillation proximity assay (SPA) which mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7RKDUS Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM283156(N-[1-{N′-cyano-N-[2-fluoro-3-(trifluorometho...)copy SMILEScopy InChI
Affinity DataIC50: 54.1nMpH: 9.0Assay Description:SMYD2 inhibitory activities of the compounds described in the present invention were quantified using a scintillation proximity assay (SPA) which mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7RKDUS Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM283168(Rac-N-[1-(N′-cyano-N-{3-[2-(dimethylamino)et...)copy SMILEScopy InChI
Affinity DataIC50: 59.5nMpH: 9.0Assay Description:SMYD2 inhibitory activities of the compounds described in the present invention were quantified using a scintillation proximity assay (SPA) which mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7RKDUS Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM50180955(CHEMBL3818617)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of N-terminal 2xc-myc-tagged human SMYD2 transfected in human MDA-MB-231 cells assessed as reduction in AHNAK methylation after 72 hrs by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN39S5PubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
BAYER Pharma AG

Curated by ChEMBL
LigandPNGBDBM50181511(CHEMBL3819343)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Antagonist activity at PAR1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN39S5PubMed
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