Compile Data Set for Download or QSAR
Found 40 with Last Name = 'tardif' and Initial = 'c'
TargetNeutrophil elastase(Homo sapiens (Human))
Hoechst Marion Roussel Inc.

Curated by ChEMBL
LigandPNGBDBM50065147((S)-1-{(S)-3-Methyl-2-[4-(morpholine-4-carbonyl)-b...)copy SMILEScopy InChI
Affinity DataKi:  18nMAssay Description:Inhibition of human neutrophil elastase in hamster lungs following 25 mg/kg pre-treatment before instillation of elastase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X85S8PubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Hoechst Marion Roussel Inc.

Curated by ChEMBL
LigandPNGBDBM50065158((R)-4-Benzyloxy-1-{(S)-3-methyl-2-[4-(morpholine-4...)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:Inhibition of human neutrophil elastase in hamster lungs following 25 mg/kg pre-treatment before instillation of elastase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X85S8PubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Hoechst Marion Roussel Inc.

Curated by ChEMBL
LigandPNGBDBM50035495((S)-1-{(S)-3-Methyl-2-[4-(morpholine-4-carbonyl)-b...)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:Inhibition of human neutrophil elastase in hamster lungs following 25 mg/kg pre-treatment before instillation of elastase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X85S8PubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Hoechst Marion Roussel Inc.

Curated by ChEMBL
LigandPNGBDBM50065157((R)-1-{(S)-3-Methyl-2-[4-(morpholine-4-carbonyl)-b...)copy SMILEScopy InChI
Affinity DataKi:  34nMAssay Description:Inhibition of human neutrophil elastase in hamster lungs following 25 mg/kg pre-treatment before instillation of elastase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X85S8PubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Hoechst Marion Roussel Inc.

Curated by ChEMBL
LigandPNGBDBM50065161(Acetic acid 1-{(S)-3-methyl-2-[4-(morpholine-4-car...)copy SMILEScopy InChI
Affinity DataKi:  40nMAssay Description:Inhibition of human neutrophil elastase in hamster lungs following 25 mg/kg pre-treatment before instillation of elastase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X85S8PubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Hoechst Marion Roussel Inc.

Curated by ChEMBL
LigandPNGBDBM50065163((R)-3-{(S)-3-Methyl-2-[4-(morpholine-4-carbonyl)-b...)copy SMILEScopy InChI
Affinity DataKi:  70nMAssay Description:Inhibition of human neutrophil elastase in hamster lungs following 25 mg/kg pre-treatment before instillation of elastase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X85S8PubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Hoechst Marion Roussel Inc.

Curated by ChEMBL
LigandPNGBDBM50065155(2-{(S)-3-Methyl-2-[4-(morpholine-4-carbonyl)-benzo...)copy SMILEScopy InChI
Affinity DataKi:  100nMAssay Description:Inhibition of human neutrophil elastase in hamster lungs following 25 mg/kg pre-treatment before instillation of elastase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X85S8PubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Hoechst Marion Roussel Inc.

Curated by ChEMBL
LigandPNGBDBM50065154(4-Hydroxy-1-{(S)-3-methyl-2-[4-(morpholine-4-carbo...)copy SMILEScopy InChI
Affinity DataKi:  120nMAssay Description:Inhibition of human neutrophil elastase in hamster lungs following 25 mg/kg pre-treatment before instillation of elastase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X85S8PubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Hoechst Marion Roussel Inc.

Curated by ChEMBL
LigandPNGBDBM50065146(1-{(S)-3-Methyl-2-[4-(morpholine-4-carbonyl)-benzo...)copy SMILEScopy InChI
Affinity DataKi:  150nMAssay Description:Inhibition of human neutrophil elastase in hamster lungs following 25 mg/kg pre-treatment before instillation of elastase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X85S8PubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Hoechst Marion Roussel Inc.

Curated by ChEMBL
LigandPNGBDBM50065164((S)-1-{(R)-3,3-Dimethyl-2-[4-(morpholine-4-carbony...)copy SMILEScopy InChI
Affinity DataKi:  240nMAssay Description:Inhibition of human neutrophil elastase in hamster lungs following 25 mg/kg pre-treatment before instillation of elastase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X85S8PubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Hoechst Marion Roussel Inc.

Curated by ChEMBL
LigandPNGBDBM50065156((S)-1-{(R)-3,3-Dimethyl-2-[4-(morpholine-4-carbony...)copy SMILEScopy InChI
Affinity DataKi:  340nMAssay Description:Inhibition of human neutrophil elastase in hamster lungs following 25 mg/kg pre-treatment before instillation of elastase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X85S8PubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Hoechst Marion Roussel Inc.

Curated by ChEMBL
LigandPNGBDBM50065162((S)-1-{(R)-3,3-Dimethyl-2-[4-(morpholine-4-carbony...)copy SMILEScopy InChI
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of human neutrophil elastase in hamster lungs following 25 mg/kg pre-treatment before instillation of elastase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X85S8PubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Hoechst Marion Roussel Inc.

Curated by ChEMBL
LigandPNGBDBM50065153((S)-1-[3-Methyl-2-(2-oxo-2-phenyl-ethyl)-butyryl]-...)copy SMILEScopy InChI
Affinity DataKi:  4.20E+3nMAssay Description:Inhibition of human neutrophil elastase in hamster lungs following 25 mg/kg pre-treatment before instillation of elastase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X85S8PubMed
TargetOrnithine decarboxylase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50009841(CHEMBL3247544)copy SMILEScopy InChI
Affinity DataKi:  4.40E+3nMAssay Description:Inhibition of rat liver ornithine decarboxylaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8TQPPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Hoechst Marion Roussel Inc.

Curated by ChEMBL
LigandPNGBDBM50065151((S)-1-{(R)-3-Methyl-2-[4-(morpholine-4-carbonyl)-b...)copy SMILEScopy InChI
Affinity DataKi:  5.50E+3nMAssay Description:Inhibition of human neutrophil elastase in hamster lungs following 25 mg/kg pre-treatment before instillation of elastase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X85S8PubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Hoechst Marion Roussel Inc.

Curated by ChEMBL
LigandPNGBDBM50065150((S)-1-[3-Methyl-2-(2-morpholin-4-yl-2-oxo-ethyl)-b...)copy SMILEScopy InChI
Affinity DataKi:  9.80E+3nMAssay Description:Inhibition of human neutrophil elastase in hamster lungs following 25 mg/kg pre-treatment before instillation of elastase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X85S8PubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Hoechst Marion Roussel Inc.

Curated by ChEMBL
LigandPNGBDBM50065148(4-(Morpholine-4-carbonyl)-N-{(S)-2-oxo-1-[(S)-1-(3...)copy SMILEScopy InChI
Affinity DataKi:  1.40E+4nMAssay Description:Inhibition of human neutrophil elastase in hamster lungs following 25 mg/kg pre-treatment before instillation of elastase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X85S8PubMed
TargetOrnithine decarboxylase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50009922(CHEMBL3247533)copy SMILEScopy InChI
Affinity DataKi:  1.90E+4nMAssay Description:Competitive inhibition of rat liver ornithine decarboxylase using DL-[1-14C]ornithine as substrate after 1 hr by dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8TQPPubMed
TargetOrnithine decarboxylase(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM50009922(CHEMBL3247533)copy SMILEScopy InChI
Affinity DataKi:  2.00E+4nMAssay Description:Competitive inhibition of bull prostate ornithine decarboxylase using DL-[1-14C]ornithine as substrate after 1 hr by dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8TQPPubMed
TargetOrnithine decarboxylase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50009922(CHEMBL3247533)copy SMILEScopy InChI
Affinity DataKi:  2.00E+4nMAssay Description:Competitive inhibition of ornithine decarboxylase in rat HTC cells using DL-[1-14C]ornithine as substrate after 1 hr by dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8TQPPubMed
TargetOrnithine decarboxylase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50028201(2,5-Diamino-2-methyl-pentanoic acid | CHEMBL36743)copy SMILEScopy InChI
Affinity DataKi:  4.00E+4nMAssay Description:Competitive inhibition of ornithine decarboxylase in rat HTC cells using DL-[1-14C]ornithine as substrate after 1 hr by dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8TQPPubMed
TargetOrnithine decarboxylase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50028201(2,5-Diamino-2-methyl-pentanoic acid | CHEMBL36743)copy SMILEScopy InChI
Affinity DataKi:  4.00E+4nMAssay Description:Competitive inhibition of rat liver ornithine decarboxylase using DL-[1-14C]ornithine as substrate after 1 hr by dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8TQPPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Hoechst Marion Roussel Inc.

Curated by ChEMBL
LigandPNGBDBM50065159((S)-1-[3-Methyl-2-(2-morpholin-4-yl-2-oxo-ethyl)-b...)copy SMILEScopy InChI
Affinity DataKi:  4.10E+4nMAssay Description:Inhibition of human neutrophil elastase in hamster lungs following 25 mg/kg pre-treatment before instillation of elastase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X85S8PubMed
TargetOrnithine decarboxylase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50009924(CHEMBL3247542)copy SMILEScopy InChI
Affinity DataKi:  7.00E+4nMAssay Description:Competitive inhibition of rat liver ornithine decarboxylase using DL-[1-14C]ornithine as substrate after 1 hr by dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8TQPPubMed
TargetOrnithine decarboxylase(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM50009740(CHEMBL3247539)copy SMILEScopy InChI
Affinity DataKi:  7.00E+4nMAssay Description:Competitive inhibition of bull prostate ornithine decarboxylase using DL-[1-14C]ornithine as substrate after 1 hr by dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8TQPPubMed
TargetOrnithine decarboxylase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50009924(CHEMBL3247542)copy SMILEScopy InChI
Affinity DataKi:  7.00E+4nMAssay Description:Competitive inhibition of ornithine decarboxylase in rat HTC cells using DL-[1-14C]ornithine as substrate after 1 hr by dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8TQPPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Hoechst Marion Roussel Inc.

Curated by ChEMBL
LigandPNGBDBM50065160(4-(Morpholine-4-carbonyl)-N-{(R)-2-oxo-1-[(3,3,4,4...)copy SMILEScopy InChI
Affinity DataKi:  9.50E+4nMAssay Description:Inhibition of human neutrophil elastase in hamster lungs following 25 mg/kg pre-treatment before instillation of elastase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X85S8PubMed
TargetOrnithine decarboxylase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50009740(CHEMBL3247539)copy SMILEScopy InChI
Affinity DataKi:  1.20E+5nMAssay Description:Competitive inhibition of rat liver ornithine decarboxylase using DL-[1-14C]ornithine as substrate after 1 hr by dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8TQPPubMed
TargetOrnithine decarboxylase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50009740(CHEMBL3247539)copy SMILEScopy InChI
Affinity DataKi:  1.40E+5nMAssay Description:Competitive inhibition of ornithine decarboxylase in rat HTC cells using DL-[1-14C]ornithine as substrate after 1 hr by dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8TQPPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Hoechst Marion Roussel Inc.

Curated by ChEMBL
LigandPNGBDBM50065149(4-(Morpholine-4-carbonyl)-N-{(R)-2-oxo-1-[(3,3,4,4...)copy SMILEScopy InChI
Affinity DataKi:  4.00E+5nMAssay Description:Inhibition of human neutrophil elastase in hamster lungs following 25 mg/kg pre-treatment before instillation of elastase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X85S8PubMed
TargetOrnithine decarboxylase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50009921(CHEMBL3247530)copy SMILEScopy InChI
Affinity DataKi:  5.00E+5nMAssay Description:Competitive inhibition of rat liver ornithine decarboxylase using DL-[1-14C]ornithine as substrate after 1 hr by dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8TQPPubMed
TargetOrnithine decarboxylase(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM50009921(CHEMBL3247530)copy SMILEScopy InChI
Affinity DataKi:  7.40E+5nMAssay Description:Competitive inhibition of bull prostate ornithine decarboxylase using DL-[1-14C]ornithine as substrate after 1 hr by dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8TQPPubMed
TargetOrnithine decarboxylase(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM50009923(CHEMBL3247534)copy SMILEScopy InChI
Affinity DataKi:  1.00E+6nMAssay Description:Competitive inhibition of bull prostate ornithine decarboxylase using DL-[1-14C]ornithine as substrate after 1 hr by dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8TQPPubMed
TargetOrnithine decarboxylase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50009923(CHEMBL3247534)copy SMILEScopy InChI
Affinity DataKi:  1.05E+6nMAssay Description:Competitive inhibition of ornithine decarboxylase in rat HTC cells using DL-[1-14C]ornithine as substrate after 1 hr by dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8TQPPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Hoechst Marion Roussel Inc.

Curated by ChEMBL
LigandPNGBDBM50065152(4-(Morpholine-4-carbonyl)-N-{(R)-2-oxo-1-[(S)-1-(3...)copy SMILEScopy InChI
Affinity DataKi:  1.10E+6nMAssay Description:Inhibition of human neutrophil elastase in hamster lungs following 25 mg/kg pre-treatment before instillation of elastase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X85S8PubMed
TargetOrnithine decarboxylase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50009923(CHEMBL3247534)copy SMILEScopy InChI
Affinity DataKi:  1.30E+6nMAssay Description:Competitive inhibition of rat liver ornithine decarboxylase using DL-[1-14C]ornithine as substrate after 1 hr by dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8TQPPubMed
TargetOrnithine decarboxylase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50009353(1,5,10-triazadecane | 4-azaoctamethylenediamine | ...)copy SMILEScopy InChI
Affinity DataKi:  2.70E+6nMAssay Description:Competitive inhibition of Sprague-Dawley rat prostate ornithine decarboxylase using DL-[1-14C]ornithine as substrate by liquid scintillation counting...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8TQPPubMed
TargetOrnithine decarboxylase(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM50009353(1,5,10-triazadecane | 4-azaoctamethylenediamine | ...)copy SMILEScopy InChI
Affinity DataKi:  3.00E+6nMAssay Description:Competitive inhibition of bull prostate ornithine decarboxylase using DL-[1-14C]ornithine as substrate after 1 hr by dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8TQPPubMed
TargetOrnithine decarboxylase(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM50009925(CHEMBL3247532)copy SMILEScopy InChI
Affinity DataKi:  4.40E+6nMAssay Description:Competitive inhibition of bull prostate ornithine decarboxylase using DL-[1-14C]ornithine as substrate after 1 hr by dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8TQPPubMed
TargetOrnithine decarboxylase(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM50009925(CHEMBL3247532)copy SMILEScopy InChI
Affinity DataKi:  5.50E+6nMAssay Description:Competitive inhibition of bull prostate ornithine decarboxylase using DL-[1-14C]ornithine as substrate after 1 hr by dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8TQPPubMed