Compile Data Set for Download or QSAR
Found 30 with Last Name = 'thiemermann' and Initial = 'c'
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Konstanz

LigandPNGBDBM27493(2-[4-(5-methyl-1H-imidazol-4-yl)piperidin-1-yl]-1,...)copy SMILEScopy InChI
Affinity DataIC50: 4.40nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61HKGPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Konstanz

LigandPNGBDBM27494(2-[4-(pyridin-2-yl)phenyl]-1,3-diazatricyclo[6.3.1...)copy SMILEScopy InChI
Affinity DataIC50: 15.4nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61HKGPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Konstanz

LigandPNGBDBM27497(2-(dimethylamino)-N-(6-oxo-5,6-dihydrophenanthridi...)copy SMILEScopy InChI
Affinity DataIC50: 19nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
University of Konstanz

LigandPNGBDBM27493(2-[4-(5-methyl-1H-imidazol-4-yl)piperidin-1-yl]-1,...)copy SMILEScopy InChI
Affinity DataIC50: 20nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61HKGPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Konstanz

LigandPNGBDBM27498(10-amino-3-azatricyclo[7.3.1.0^{5,13}]trideca-1(13...)copy SMILEScopy InChI
Affinity DataIC50: 22nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
University of Konstanz

LigandPNGBDBM27494(2-[4-(pyridin-2-yl)phenyl]-1,3-diazatricyclo[6.3.1...)copy SMILEScopy InChI
Affinity DataIC50: 28nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61HKGPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
University of Konstanz

LigandPNGBDBM27498(10-amino-3-azatricyclo[7.3.1.0^{5,13}]trideca-1(13...)copy SMILEScopy InChI
Affinity DataIC50: 32nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61HKGPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Konstanz

LigandPNGBDBM27496((4Z)-4-[(1-methyl-1H-pyrrol-2-yl)methylidene]-1,2,...)copy SMILEScopy InChI
Affinity DataIC50: 45nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61HKGPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
University of Konstanz

LigandPNGBDBM27497(2-(dimethylamino)-N-(6-oxo-5,6-dihydrophenanthridi...)copy SMILEScopy InChI
Affinity DataIC50: 62nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61HKGPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Konstanz

LigandPNGBDBM27499(1,11b-dihydro-[2H]benzopyrano[4,3,2-de]isoquinolin...)copy SMILEScopy InChI
Affinity DataIC50: 83nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61HKGPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Konstanz

LigandPNGBDBM27500(5,6-dihydrophenanthridin-6-one | 5H-Phenanthridin-...)copy SMILEScopy InChI
Affinity DataIC50: 85nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61HKGPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Konstanz

LigandPNGBDBM27501(1,5-dihydroxyisoquinoline | CHEMBL338314 | ISQ | i...)copy SMILEScopy InChI
Affinity DataIC50: 151nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61HKGPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
University of Konstanz

LigandPNGBDBM27499(1,11b-dihydro-[2H]benzopyrano[4,3,2-de]isoquinolin...)copy SMILEScopy InChI
Affinity DataIC50: 186nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61HKGPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
University of Konstanz

LigandPNGBDBM27500(5,6-dihydrophenanthridin-6-one | 5H-Phenanthridin-...)copy SMILEScopy InChI
Affinity DataIC50: 331nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61HKGPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Konstanz

LigandPNGBDBM27502(3,4-dihydro-5-(4-(1-piperidinyl)butoxy)-1(2H)-isoq...)copy SMILEScopy InChI
Affinity DataIC50: 372nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61HKGPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Konstanz

LigandPNGBDBM27495(6-chloro-2,3-dimethylimidazo[1,2-a]pyridin-8-ol | ...)copy SMILEScopy InChI
Affinity DataIC50: 398nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61HKGPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
University of Konstanz

LigandPNGBDBM27501(1,5-dihydroxyisoquinoline | CHEMBL338314 | ISQ | i...)copy SMILEScopy InChI
Affinity DataIC50: 447nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61HKGPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Konstanz

LigandPNGBDBM27503(5-AIQ | 5-amino-1,2-dihydroisoquinolin-1-one | 5-a...)copy SMILEScopy InChI
Affinity DataIC50: 1.18E+3nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61HKGPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
University of Konstanz

LigandPNGBDBM27502(3,4-dihydro-5-(4-(1-piperidinyl)butoxy)-1(2H)-isoq...)copy SMILEScopy InChI
Affinity DataIC50: 1.74E+3nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61HKGPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
University of Konstanz

LigandPNGBDBM27503(5-AIQ | 5-amino-1,2-dihydroisoquinolin-1-one | 5-a...)copy SMILEScopy InChI
Affinity DataIC50: 1.82E+3nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61HKGPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
University of Konstanz

LigandPNGBDBM27495(6-chloro-2,3-dimethylimidazo[1,2-a]pyridin-8-ol | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.95E+3nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61HKGPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
University of Konstanz

LigandPNGBDBM27496((4Z)-4-[(1-methyl-1H-pyrrol-2-yl)methylidene]-1,2,...)copy SMILEScopy InChI
Affinity DataIC50: 4.17E+3nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61HKGPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Konstanz

LigandPNGBDBM27504(4-HQN | 4-hydroxyquinazoline | CHEMBL266540 | quin...)copy SMILEScopy InChI
Affinity DataIC50: 5.89E+3nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61HKGPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Konstanz

LigandPNGBDBM27505(5-Iabp | 5-iodo-6-amino-1,2-benzopyrone | 6-amino-...)copy SMILEScopy InChI
Affinity DataIC50: 8.51E+3nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61HKGPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Konstanz

LigandPNGBDBM27506(3-AB | 3-aminobenzamide | CHEMBL81977)copy SMILEScopy InChI
Affinity DataIC50: 1.29E+4nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61HKGPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
University of Konstanz

LigandPNGBDBM27505(5-Iabp | 5-iodo-6-amino-1,2-benzopyrone | 6-amino-...)copy SMILEScopy InChI
Affinity DataIC50: 1.78E+4nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61HKGPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
University of Konstanz

LigandPNGBDBM27504(4-HQN | 4-hydroxyquinazoline | CHEMBL266540 | quin...)copy SMILEScopy InChI
Affinity DataIC50: 2.57E+4nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61HKGPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
University of Konstanz

LigandPNGBDBM27506(3-AB | 3-aminobenzamide | CHEMBL81977)copy SMILEScopy InChI
Affinity DataIC50: 4.17E+4nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Konstanz

LigandPNGBDBM27507(3-Pyridinecarboxamide | CHEMBL1140 | NAM | niacina...)copy SMILEScopy InChI
Affinity DataIC50: 5.01E+4nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61HKGPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
University of Konstanz

LigandPNGBDBM27507(3-Pyridinecarboxamide | CHEMBL1140 | NAM | niacina...)copy SMILEScopy InChI
Affinity DataIC50: 2.09E+5nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61HKGPubMed