Affinity DataKi: 0.340nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Affinity DataKi: 0.420nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Affinity DataKi: 0.480nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Affinity DataKi: 6.40nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Affinity DataKi: 6.5nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Affinity DataKi: 7.80nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Affinity DataKi: 8.20nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Inhibition of IRAK-1 (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Inhibition of TAK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Inhibition of IRAK-1 (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Inhibition of TAK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 39nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Affinity DataKi: 48nMAssay Description:Inhibition of IRAK-1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 72nMAssay Description:Inhibition of IRAK-1 (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataKi: 130nMAssay Description:Inhibition of TAK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 374nMAssay Description:Inhibition of IRAK-1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 608nMAssay Description:Inhibition of IRAK-1 (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataKi: 700nMAssay Description:Inhibition of TAK1 (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataKi: 800nMAssay Description:Inhibition of TAK1 (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataKi: 1.30E+3nMAssay Description:Inhibition of TAK1 (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataKi: 2.50E+3nMAssay Description:Inhibition of TAK1 (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataKi: 2.50E+3nMAssay Description:Inhibition of TAK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 4.50E+3nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 3nM EC50: 57nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
Affinity DataIC50: 3nM EC50: 315nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Enzyme assays were performed using purified recombinant mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine en...More data for this Ligand-Target Pair
Affinity DataIC50: 4nM EC50: 201nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Enzyme assays were performed using purified recombinant mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine en...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Enzyme assays were performed using purified recombinant mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine en...More data for this Ligand-Target Pair
Affinity DataIC50: 7nM EC50: 241nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
Affinity DataIC50: 9nM EC50: 632nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
Affinity DataIC50: 9nM EC50: 569nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Enzyme assays were performed using purified recombinant mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine en...More data for this Ligand-Target Pair
Affinity DataIC50: 10nM EC50: 247nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Enzyme assays were performed using purified recombinant mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine en...More data for this Ligand-Target Pair
Affinity DataIC50: 11nM EC50: 762nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
Affinity DataIC50: 13nM EC50: 547nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
Affinity DataIC50: 13nM EC50: 329nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
Affinity DataIC50: 14nM EC50: 518nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
Affinity DataIC50: 14nM EC50: 727nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
Affinity DataIC50: 15nM EC50: 971nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
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