TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation
Curated by ChEMBL
NewLink Genetics Corporation
Curated by ChEMBL
Affinity DataKi: 5.80nMAssay Description:Inhibition of purified human IDO1 using varying levels of L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of CYP3A4 (unknown origin) using midazolam as substrateMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation
Curated by ChEMBL
NewLink Genetics Corporation
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation
Curated by ChEMBL
NewLink Genetics Corporation
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation
Curated by ChEMBL
NewLink Genetics Corporation
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation
Curated by ChEMBL
NewLink Genetics Corporation
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation
Curated by ChEMBL
NewLink Genetics Corporation
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation
Curated by ChEMBL
NewLink Genetics Corporation
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation
Curated by ChEMBL
NewLink Genetics Corporation
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation
Curated by ChEMBL
NewLink Genetics Corporation
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation
Curated by ChEMBL
NewLink Genetics Corporation
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of CYP3A4 (unknown origin) using midazolam as substrateMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation
Curated by ChEMBL
NewLink Genetics Corporation
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation
Curated by ChEMBL
NewLink Genetics Corporation
Curated by ChEMBL
Affinity DataIC50: 72nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation
Curated by ChEMBL
NewLink Genetics Corporation
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation
Curated by ChEMBL
NewLink Genetics Corporation
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation
Curated by ChEMBL
NewLink Genetics Corporation
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of CYP3A4 (unknown origin) using midazolam as substrateMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation
Curated by ChEMBL
NewLink Genetics Corporation
Curated by ChEMBL
Affinity DataIC50: 135nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation
Curated by ChEMBL
NewLink Genetics Corporation
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation
Curated by ChEMBL
NewLink Genetics Corporation
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of CYP3A4 (unknown origin) using midazolam as substrateMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation
Curated by ChEMBL
NewLink Genetics Corporation
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation
Curated by ChEMBL
NewLink Genetics Corporation
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation
Curated by ChEMBL
NewLink Genetics Corporation
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation
Curated by ChEMBL
NewLink Genetics Corporation
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation
Curated by ChEMBL
NewLink Genetics Corporation
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation
Curated by ChEMBL
NewLink Genetics Corporation
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation
Curated by ChEMBL
NewLink Genetics Corporation
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation
Curated by ChEMBL
NewLink Genetics Corporation
Curated by ChEMBL
Affinity DataIC50: 330nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation
Curated by ChEMBL
NewLink Genetics Corporation
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation
Curated by ChEMBL
NewLink Genetics Corporation
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation
Curated by ChEMBL
NewLink Genetics Corporation
Curated by ChEMBL
Affinity DataIC50: 440nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation
Curated by ChEMBL
NewLink Genetics Corporation
Curated by ChEMBL
Affinity DataIC50: 490nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
Affinity DataIC50: 510nMAssay Description:Inhibition of CYP3A4 (unknown origin) using midazolam as substrateMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation
Curated by ChEMBL
NewLink Genetics Corporation
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation
Curated by ChEMBL
NewLink Genetics Corporation
Curated by ChEMBL
Affinity DataIC50: 610nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation
Curated by ChEMBL
NewLink Genetics Corporation
Curated by ChEMBL
Affinity DataIC50: 640nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation
Curated by ChEMBL
NewLink Genetics Corporation
Curated by ChEMBL
Affinity DataIC50: 670nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of CYP3A4 (unknown origin) using midazolam as substrateMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation
Curated by ChEMBL
NewLink Genetics Corporation
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation
Curated by ChEMBL
NewLink Genetics Corporation
Curated by ChEMBL
Affinity DataIC50: 760nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation
Curated by ChEMBL
NewLink Genetics Corporation
Curated by ChEMBL
Affinity DataIC50: 790nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation
Curated by ChEMBL
NewLink Genetics Corporation
Curated by ChEMBL
Affinity DataIC50: 810nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation
Curated by ChEMBL
NewLink Genetics Corporation
Curated by ChEMBL
Affinity DataIC50: 906nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation
Curated by ChEMBL
NewLink Genetics Corporation
Curated by ChEMBL
Affinity DataIC50: 960nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation
Curated by ChEMBL
NewLink Genetics Corporation
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin) using midazolam as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin) using midazolam as substrateMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation
Curated by ChEMBL
NewLink Genetics Corporation
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair