Compile Data Set for Download or QSAR
Found 394 with Last Name = 'fleener' and Initial = 'ca'
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123324(7-Methoxy-6-oxazol-5-yl-2-phenyl-1H-quinolin-4-one...)copy SMILEScopy InChI
Affinity DataKi:  7nMAssay Description:Inhibitory activity of the compound against IMPDH II with respect to IMP and NADMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123335(2-(3,4-Dimethyl-phenyl)-7-methoxy-6-oxazol-5-yl-1H...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123332(7-Methoxy-2-(4-methoxy-phenyl)-6-oxazol-5-yl-1H-qu...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123317(7-Methoxy-6-oxazol-5-yl-2-p-tolyl-1H-quinolin-4-on...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50222633(CHEMBL356881)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0T7HPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50222630(CHEMBL153481)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0T7HPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123355(2-(3-Dimethylamino-indan-5-yl)-7-methoxy-6-oxazol-...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0T7HPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50126275(CHEMBL280793 | Isoquinolin-6-yl-(5-phenyl-oxazol-2...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibitory activity of the compound against inosine 5'-inosine monophosphate dehydrogenase type II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H3QPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123355(2-(3-Dimethylamino-indan-5-yl)-7-methoxy-6-oxazol-...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0T7HPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123333(2-(4-Bromo-phenyl)-7-methoxy-6-oxazol-5-yl-1H-quin...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123358(7-Methoxy-2-(4-methyl-3-morpholin-4-yl-phenyl)-6-o...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0T7HPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123321(7-Methoxy-6-oxazol-5-yl-2-m-tolyl-1H-quinolin-4-on...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50133731(CHEMBL118988 | {3-[3-(4-Cyano-3-methoxy-phenyl)-ur...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibitory activity tested against inosine-5'-monophosphate dehydrogenase 2 (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J67G94PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123355(2-(3-Dimethylamino-indan-5-yl)-7-methoxy-6-oxazol-...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibitory activity against inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0T7HPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123353(2-(3-Azetidin-1-yl-indan-5-yl)-7-methoxy-6-oxazol-...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibitory activity against inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0T7HPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50120529(Acetic acid (methyl-{2-[2-(3-oxazol-5-yl-1H-indol-...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibitory activity tested against inosine-5'-monophosphate dehydrogenase 2 (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J67G94PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50120529(Acetic acid (methyl-{2-[2-(3-oxazol-5-yl-1H-indol-...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibitory concentration against Inosine-5'-monophosphate dehydrogenase 2 was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q81CD6PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM19284(Acridone-Based Inhibitor, 4h | N-{2-[3-(dimethylsu...)copy SMILEScopy InChI
Affinity DataIC50: 7.90nM EC50:  380nMpH: 8.0 T: 2°CAssay Description:Inhibition assays were performed using recombinant human IMPDH type 2 and varying concentrations of inhibitor. The production of NADH was monitored b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58JPVPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123324(7-Methoxy-6-oxazol-5-yl-2-phenyl-1H-quinolin-4-one...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of human inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123324(7-Methoxy-6-oxazol-5-yl-2-phenyl-1H-quinolin-4-one...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z14X1PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123324(7-Methoxy-6-oxazol-5-yl-2-phenyl-1H-quinolin-4-one...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of 5'-inosine monophosphate dehydrogenase type II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T1530JPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123320(7-Methoxy-6-oxazol-5-yl-2-thiophen-3-yl-1H-quinoli...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of human inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50102249((S)-tetrahydrofuran-3-yl 3-(3-(3-methoxy-4-(oxazol...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21R6R71PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50222632(CHEMBL356236)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0T7HPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50112565(CHEMBL25138 | N-tert-Butyl-N'-(3-methoxy-4-oxazol-...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z14X1PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50102249((S)-tetrahydrofuran-3-yl 3-(3-(3-methoxy-4-(oxazol...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0T7HPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM19283(Acridone-Based Inhibitor, 4g | N-{2-[4-(dimethylsu...)copy SMILEScopy InChI
Affinity DataIC50: 10nM EC50:  660nMpH: 8.0 T: 2°CAssay Description:Inhibition assays were performed using recombinant human IMPDH type 2 and varying concentrations of inhibitor. The production of NADH was monitored b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58JPVPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50112565(CHEMBL25138 | N-tert-Butyl-N'-(3-methoxy-4-oxazol-...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human Inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NG4PX7PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50102249((S)-tetrahydrofuran-3-yl 3-(3-(3-methoxy-4-(oxazol...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibitory activity tested against inosine-5'-monophosphate dehydrogenase 2 (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J67G94PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50113219(CHEMBL68075 | N-{2-[2-(3-Methoxy-4-oxazol-5-yl-phe...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21R6R71PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50120535(1-(3-Oxazol-5-yl-1H-indol-6-yl)-3-p-tolyl-urea | C...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibitory activity tested against inosine-5'-monophosphate dehydrogenase 2 (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J67G94PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50120535(1-(3-Oxazol-5-yl-1H-indol-6-yl)-3-p-tolyl-urea | C...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibitory concentration against Inosine-5'-monophosphate dehydrogenase 2 was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q81CD6PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123350(CHEMBL423952 | Dimethyl-carbamic acid 6-(7-methoxy...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibitory activity against inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0T7HPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM19277(2-fluoro-9-oxo-N-(2-phenylpropan-2-yl)-9,10-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 11nM EC50:  830nMpH: 8.0 T: 2°CAssay Description:Inhibition assays were performed using recombinant human IMPDH type 2 and varying concentrations of inhibitor. The production of NADH was monitored b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58JPVPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM19279(2-fluoro-9-oxo-N-[2-(pyridin-3-yl)propan-2-yl]-9,1...)copy SMILEScopy InChI
Affinity DataIC50: 11nM EC50:  420nMpH: 8.0 T: 2°CAssay Description:Inhibition assays were performed using recombinant human IMPDH type 2 and varying concentrations of inhibitor. The production of NADH was monitored b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58JPVPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM19292(2-fluoro-N-{2-[5-methyl-6-(morpholin-4-yl)pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 11nM EC50:  870nMpH: 8.0 T: 2°CAssay Description:Inhibition assays were performed using recombinant human IMPDH type 2 and varying concentrations of inhibitor. The production of NADH was monitored b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58JPVPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50113230(BMS-337197 | CHEMBL64830 | N-{2-[2-(3-Methoxy-4-ox...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of human inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21R6R71PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123376(7-Methoxy-2-(3-methylamino-indan-5-yl)-6-oxazol-5-...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibitory activity against inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0T7HPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123348(2-Methoxy-N-[6-(7-methoxy-6-oxazol-5-yl-4-oxo-1,4-...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibitory activity against inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0T7HPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM19281(2-fluoro-N-[2-(4-methanesulfonylphenyl)propan-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 12nM EC50:  480nMpH: 8.0 T: 2°CAssay Description:Inhibition assays were performed using recombinant human IMPDH type 2 and varying concentrations of inhibitor. The production of NADH was monitored b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58JPVPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM19282(2-fluoro-N-[2-(3-methanesulfonylphenyl)propan-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 12nM EC50:  580nMpH: 8.0 T: 2°CAssay Description:Inhibition assays were performed using recombinant human IMPDH type 2 and varying concentrations of inhibitor. The production of NADH was monitored b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58JPVPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50113215(CHEMBL67036 | N-{2-[2-(3-Methoxy-4-oxazol-5-yl-phe...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21R6R71PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50113233(CHEMBL66614 | N-{2-[2-(3-Methoxy-4-oxazol-5-yl-phe...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21R6R71PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123361(7-Methoxy-6-oxazol-5-yl-2-(3-pyrrolidin-1-yl-indan...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibitory activity against inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0T7HPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of human inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibitory activity against inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123370(2-(4-Acetyl-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibitory activity against inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0T7HPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123367(7-Methoxy-2-(2-methyl-2,3-dihydro-1H-isoindol-5-yl...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibitory activity against inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0T7HPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM19288(Acridone-Based Inhibitor, 4l | N-{2-[2-(dimethylam...)copy SMILEScopy InChI
Affinity DataIC50: 14nM EC50:  640nMpH: 8.0 T: 2°CAssay Description:Inhibition assays were performed using recombinant human IMPDH type 2 and varying concentrations of inhibitor. The production of NADH was monitored b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58JPVPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of human inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
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