Compile Data Set for Download or QSAR
Found 508 with Last Name = 'king' and Initial = 'cd'
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172117(2-Cyclohex-1-enylethynyl-pyridine | CHEMBL196643)copy SMILEScopy InChI
Affinity DataKi:  0.650nMAssay Description:Displacement of [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from mGlu5 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB81C5PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172136(4-Pyridin-2-ylethynyl-3,6-dihydro-2H-pyridine-1-ca...)copy SMILEScopy InChI
Affinity DataKi:  0.830nMAssay Description:Displacement of [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from mGlu5 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB81C5PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172123(3-Chloro-5-(3-pyridin-2-ylethynyl-cyclohex-2-enylo...)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from mGlu5 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB81C5PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172130(2-{[3-(pyridin-3-yloxy)cyclohex-1-en-1-yl]ethynyl}...)copy SMILEScopy InChI
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from mGlu5 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB81C5PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172119(2-[1-(4-Bromo-benzenesulfonyl)-1,2,3,6-tetrahydro-...)copy SMILEScopy InChI
Affinity DataKi:  3.10nMAssay Description:Displacement of [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from mGlu5 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB81C5PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172137(CHEMBL197212 | Pyridin-3-yl-(3-pyridin-2-ylethynyl...)copy SMILEScopy InChI
Affinity DataKi:  7.30nMAssay Description:Displacement of [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from mGlu5 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB81C5PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172132(2-Cyclopent-1-enylethynyl-pyridine | CHEMBL443487)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Displacement of [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from mGlu5 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB81C5PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172118(2-[1-(Toluene-4-sulfonyl)-1,2,3,6-tetrahydro-pyrid...)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:Displacement of [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from mGlu5 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB81C5PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172126(2-[1-(Toluene-3-sulfonyl)-1,2,3,6-tetrahydro-pyrid...)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Displacement of [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from mGlu5 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB81C5PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172129(4-Pyridin-2-ylethynyl-3,6-dihydro-2H-pyridine-1-ca...)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:Displacement of [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from mGlu5 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB81C5PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172131(2-{[3-(pyridin-4-yloxy)cyclohex-1-en-1-yl]ethynyl}...)copy SMILEScopy InChI
Affinity DataKi:  21nMAssay Description:Displacement of [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from mGlu5 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB81C5PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172125(CHEMBL194407 | Pyridin-3-yl-(4-pyridin-2-ylethynyl...)copy SMILEScopy InChI
Affinity DataKi:  35nMAssay Description:Displacement of [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from mGlu5 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB81C5PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172121(2-{[3-(pyridin-4-ylthio)cyclohex-1-en-1-yl]ethynyl...)copy SMILEScopy InChI
Affinity DataKi:  43nMAssay Description:Displacement of [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from mGlu5 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB81C5PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172124(2-[3-(Naphthalen-2-ylsulfanyl)-cyclohex-1-enylethy...)copy SMILEScopy InChI
Affinity DataKi:  75nMAssay Description:Displacement of [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from mGlu5 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB81C5PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172120(2-Cyclohexylethynyl-pyridine | CHEMBL195965)copy SMILEScopy InChI
Affinity DataKi:  163nMAssay Description:Displacement of [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from mGlu5 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB81C5PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172122(4-Pyridin-2-ylethynyl-3,6-dihydro-2H-pyridine-1-ca...)copy SMILEScopy InChI
Affinity DataKi:  171nMAssay Description:Displacement of [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from mGlu5 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB81C5PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172127(CHEMBL370879 | Naphthalen-2-yl-(4-pyridin-2-ylethy...)copy SMILEScopy InChI
Affinity DataKi:  304nMAssay Description:Displacement of [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from mGlu5 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB81C5PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172135(2-(1-Phenylmethanesulfonyl-1,2,3,6-tetrahydro-pyri...)copy SMILEScopy InChI
Affinity DataKi:  389nMAssay Description:Displacement of [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from mGlu5 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB81C5PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172134(2-(1,2,3,6-Tetrahydro-pyridin-4-ylethynyl)-pyridin...)copy SMILEScopy InChI
Affinity DataKi:  3.40E+3nMAssay Description:Displacement of [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from mGlu5 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB81C5PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172128(CHEMBL196674 | Cyclopentyl-(4-pyridin-2-ylethynyl-...)copy SMILEScopy InChI
Affinity DataKi:  7.20E+3nMAssay Description:Displacement of [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from mGlu5 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB81C5PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359073(CHEMBL1922653)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q269740WPubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359077(CHEMBL1922657)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q269740WPubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359083(CHEMBL1922663)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q269740WPubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359076(CHEMBL1922656)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q269740WPubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359075(CHEMBL1922655)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q269740WPubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359082(CHEMBL1922662)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q269740WPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50029559(2-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-(qui...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44QB1PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359078(CHEMBL1922658)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q269740WPubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359079(CHEMBL1922659)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q269740WPubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50052018(3-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-(qui...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q269740WPubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359062(CHEMBL1922642)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q269740WPubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359085(CHEMBL1922665)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Displacement of [3H]-3-[5-(pyrid-2-ylmethoxy)-3-tert-butylthio-1-benzylindol-2-yl]-2,2-dimethylpropionic acid from FLAP in human polymorphonuclear ce...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q269740WPubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297385(3-[3-tert-Butylsulfanyl-1-[4-(6-methoxy-pyridin-3-...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q269740WPubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359061(CHEMBL1922532)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q269740WPubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359086(CHEMBL1922666)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Displacement of [3H]-3-[5-(pyrid-2-ylmethoxy)-3-tert-butylthio-1-benzylindol-2-yl]-2,2-dimethylpropionic acid from FLAP in human polymorphonuclear ce...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q269740WPubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359084(CHEMBL1922664)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Displacement of [3H]-3-[5-(pyrid-2-ylmethoxy)-3-tert-butylthio-1-benzylindol-2-yl]-2,2-dimethylpropionic acid from FLAP in human polymorphonuclear ce...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q269740WPubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359063(CHEMBL1922643)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q269740WPubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359065(CHEMBL1922645)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q269740WPubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359088(CHEMBL1229205)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q269740WPubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359081(CHEMBL1922661)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q269740WPubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359067(CHEMBL1922647)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q269740WPubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359095(CHEMBL1922524)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q269740WPubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359066(CHEMBL1922646)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q269740WPubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359080(CHEMBL1922660)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q269740WPubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359096(CHEMBL1922525)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q269740WPubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359094(CHEMBL1922523)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q269740WPubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359074(CHEMBL1922654)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q269740WPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172123(3-Chloro-5-(3-pyridin-2-ylethynyl-cyclohex-2-enylo...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:In vitro inhibitory concentration against Ca+2 flux mediated by human mGlu5 receptor expressed in Ltk cells using fura-2 dyeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB81C5PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50052018(3-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-(qui...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 1 hr by ELISA in a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q269740WPubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359080(CHEMBL1922660)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 5 mins by ELISA in...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q269740WPubMed
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