Compile Data Set for Download or QSAR
Found 9 with Last Name = 'knezevic' and Initial = 'ce'
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center & Research Institute

LigandPNGBDBM50446130(AG-014699 | AG-14447 | RUCAPARIB CAMSYLATE | Rucap...)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:Inhibition of PARP1 was assessed using the Universal Chemiluminescent PARPKit. Luminescence readings were normalized to controls and fit to a sigmoid...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center & Research Institute

LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Inhibition of PARP1 was assessed using the Universal Chemiluminescent PARPKit. Luminescence readings were normalized to controls and fit to a sigmoid...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center & Research Institute

LigandPNGBDBM209931(c-Rucaparib)copy SMILEScopy InChI
Affinity DataIC50: 4.40nMAssay Description:Inhibition of PARP1 was assessed using the Universal Chemiluminescent PARPKit. Luminescence readings were normalized to controls and fit to a sigmoid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2V0BPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center & Research Institute

LigandPNGBDBM209930(c-Olaparib)copy SMILEScopy InChI
Affinity DataIC50: 5.90nMAssay Description:Inhibition of PARP1 was assessed using the Universal Chemiluminescent PARPKit. Luminescence readings were normalized to controls and fit to a sigmoid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2V0BPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center & Research Institute

LigandPNGBDBM209933(c-Veliparib)copy SMILES
Affinity DataIC50: 8.40nMAssay Description:Inhibition of PARP1 was assessed using the Universal Chemiluminescent PARPKit. Luminescence readings were normalized to controls and fit to a sigmoid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2V0BPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center & Research Institute

LigandPNGBDBM209932(2-[(2R)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-...)copy SMILEScopy InChI
Affinity DataIC50: 10.3nMAssay Description:Inhibition of PARP1 was assessed using the Universal Chemiluminescent PARPKit. Luminescence readings were normalized to controls and fit to a sigmoid...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2V0BPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center & Research Institute

LigandPNGBDBM50316226((S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-car...)copy SMILEScopy InChI
Affinity DataIC50: 11.7nMAssay Description:Inhibition of PARP1 was assessed using the Universal Chemiluminescent PARPKit. Luminescence readings were normalized to controls and fit to a sigmoid...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center & Research Institute

LigandPNGBDBM209929(c-Niraparib)copy SMILEScopy InChI
Affinity DataIC50: 48.4nMAssay Description:Inhibition of PARP1 was assessed using the Universal Chemiluminescent PARPKit. Luminescence readings were normalized to controls and fit to a sigmoid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2V0BPubMed
TargetGDH/6PGL endoplasmic bifunctional protein(Homo sapiens (Human))
H. Lee Moffitt Cancer Center & Research Institute

LigandPNGBDBM50446130(AG-014699 | AG-14447 | RUCAPARIB CAMSYLATE | Rucap...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+4nMAssay Description:HEK293 H6PD-OE and HEK293 pellets were lysed and the lysate was quantified with the Bradford protein assay. Reaction mix containing galactose-6-phosp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2V0BPubMed