Found 158 with Last Name = 'saluste' and Initial = 'cg' TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:Inhibition of human PI3Kalpha (p110alpha/p85alpha) by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Affinity DataKi: 2.40nMAssay Description:Inhibition of human PI3Kalpha (p110alpha/p85alpha) by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Affinity DataKi: 5.06nMAssay Description:Inhibition of human PI3Kdelta (p110delta/p85alpha) by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Affinity DataKi: 6.20nMAssay Description:Inhibition of human PI3Kalpha (p110alpha/p85alpha) by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Affinity DataKi: 7.40nMAssay Description:Inhibition of human PI3Kalpha (p110alpha/p85alpha) by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Affinity DataKi: 9.80nMAssay Description:Inhibition of human PI3Kdelta (p110delta/p85alpha) by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Affinity DataKi: 10.1nMAssay Description:Inhibition of human PI3Kalpha (p110alpha/p85alpha) by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Affinity DataKi: 14.2nMAssay Description:Inhibition of human PI3Kdelta (p110delta/p85alpha) by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Affinity DataKi: 14.7nMAssay Description:Inhibition of human PI3Kdelta (p110delta/p85alpha) by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Affinity DataKi: 15.6nMAssay Description:Inhibition of human PI3Kdelta (p110delta/p85alpha) by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Affinity DataKi: 26.7nMAssay Description:Inhibition of human PI3Kgamma by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Affinity DataKi: 59.8nMAssay Description:Inhibition of human PI3Kgamma by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Affinity DataKi: 84nMAssay Description:Inhibition of human PI3Kgamma by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Affinity DataKi: 124nMAssay Description:Inhibition of human PI3Kgamma by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Affinity DataKi: 179nMAssay Description:Inhibition of human PI3Kgamma by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human PI3Kalpha (p110alpha/p85alpha) by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of Lck by HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Affinity DataIC50: 2.34nMAssay Description:Inhibition of human PI3Kalpha (p110alpha/p85alpha) by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human PI3Kalpha (p110alpha/p85alpha) by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human PI3Kalpha (p110alpha/p85alpha) by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human PI3Kalpha (p110alpha/p85alpha) by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of KDR by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of Lck by HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Affinity DataIC50: 5.20nMAssay Description:Inhibition of PI3Kalpha in human U2OS cells assessed as inhibition of AKT Ser 473 phosphorylation by Western blotMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Affinity DataIC50: 5.5nMAssay Description:Inhibition of human PI3Kalpha (p110alpha/p85alpha) by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of Lck by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of Lck by HTRF assayMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 6nMAssay Description:Inhibition of Lck by HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Affinity DataIC50: 6.80nMAssay Description:Inhibition of human PI3Kalpha (p110alpha/p85alpha) by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Affinity DataIC50: 6.80nMAssay Description:Inhibition of human PI3Kalpha (p110alpha/p85alpha) by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of KDR by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of Lck by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of Lck by HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Affinity DataIC50: 8.10nMAssay Description:Inhibition of PI3Kalpha in human U2OS cells assessed as inhibition of AKT Ser 473 phosphorylation by Western blotMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Affinity DataIC50: 8.30nMAssay Description:Inhibition of PI3Kalpha in human U2OS cells assessed as inhibition of AKT Ser 473 phosphorylation by Western blotMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of Lck by HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human PI3Kalpha (p110alpha/p85alpha) by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of Lck by HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Affinity DataIC50: 10.2nMAssay Description:Inhibition of PI3Kalpha in human U2OS cells assessed as inhibition of AKT Ser 473 phosphorylation by Western blotMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Affinity DataIC50: 11.4nMAssay Description:Inhibition of human PI3Kalpha (p110alpha/p85alpha) by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of Lck by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of Lck by HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of human PI3Kalpha (p110alpha/p85alpha) by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Affinity DataIC50: 13.3nMAssay Description:Inhibition of human PI3Kalpha (p110alpha/p85alpha) by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Affinity DataIC50: 15.4nMAssay Description:Inhibition of PI3Kalpha in human U2OS cells assessed as inhibition of AKT Ser 473 phosphorylation by Western blotMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Affinity DataIC50: 16.4nMAssay Description:Inhibition of human PI3Kalpha (p110alpha/p85alpha) by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of Lck by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of Lck by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of Lyn by HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
Affinity DataIC50: 21.1nMAssay Description:Inhibition of human PI3Kalpha (p110alpha/p85alpha) by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
