Compile Data Set for Download or QSAR
Found 256 with Last Name = 'gertzen' and Initial = 'cgw'
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM207629(US9265734, R01 | US9796664, Compound R01)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Inhibition of recombinant HDAC3 (unknown origin)/NCOR2 (unknown origin) using acetyl-Lys(Ac)-AMC as substrate preincubated for up to 3 hrs followed b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8J5FPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM207629(US9265734, R01 | US9796664, Compound R01)copy SMILEScopy InChI
Affinity DataKi:  32nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) using acetyl-Lys(Ac)-AMC as substrate preincubated for up to 3 hrs followed by substrate addition an...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8J5FPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM50239858(CHEMBL4067006)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells Z-(Ac)Lys-AMC as substrate measur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SWDPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM50239857(CHEMBL4070745)copy SMILEScopy InChI
Affinity DataIC50: 6.10nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells Z-(Ac)Lys-AMC as substrate measur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SWDPubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM50239824(CHEMBL4069631)copy SMILEScopy InChI
Affinity DataIC50: 6.5nMAssay Description:Compound was tested for the binding affinity towards nicotinic acetylcholine receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P125ZPubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 9.70nMAssay Description:Inhibition of human recombinant full length C-terminal His-tagged HDAC3 (1 to 428 residues)/N-terminal GST-tagged NCOR2 (395 to 489 residues) express...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8J5FPubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of full length human recombinant C-terminal His-tagged HDAC3/NcoR2 expressed in baculovirus infected Sf9 insect cells using Boc-Lys(epsilo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P125ZPubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM50239822(CHEMBL4080343)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of full length human recombinant C-terminal His-tagged HDAC3/NcoR2 expressed in baculovirus infected Sf9 insect cells using Boc-Lys(epsilo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P125ZPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM50239832(CHEMBL4090647)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of C-terminal FLAG/His-tagged recombinant human HDAC1 expressed in baculovirus infected Sf9 insect cells using Z-(Ac)Lys-AMC as substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P125ZPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM50239859(CHEMBL4088276)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells Z-(Ac)Lys-AMC as substrate measur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SWDPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM50239824(CHEMBL4069631)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of C-terminal FLAG/His-tagged recombinant human HDAC1 expressed in baculovirus infected Sf9 insect cells using Z-(Ac)Lys-AMC as substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P125ZPubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM50239832(CHEMBL4090647)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of full length human recombinant C-terminal His-tagged HDAC3/NcoR2 expressed in baculovirus infected Sf9 insect cells using Boc-Lys(epsilo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P125ZPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM50239819(CHEMBL4095934)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of C-terminal FLAG/His-tagged recombinant human HDAC1 expressed in baculovirus infected Sf9 insect cells using Z-(Ac)Lys-AMC as substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P125ZPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM50525643(CHEMBL4437165)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of recombinant human full length C-terminal Flag/His-tagged HDAC1 expressed in baculovirus infected Sf9 cells using ZMAL as substrate incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833WFVPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of recombinant human full length C-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 cells using ZMAL as substrate incubated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833WFVPubMedDrugBank
TargetHistone deacetylase 1(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM50509450(CHEMBL4474656)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of recombinant human full length C-terminal His/FLAG-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells using ZMAL as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8J5FPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM50509458(CHEMBL4553076)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of recombinant human full length C-terminal His/FLAG-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells using ZMAL as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8J5FPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM50239858(CHEMBL4067006)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant full length human C-terminal FLAG/His-tagged HDAC1 expressed in baculovirus infected sf9 cells using Z-(Ac)Lys-AMC as subst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SWDPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant full length human C-terminal FLAG/His-tagged HDAC1 expressed in baculovirus infected sf9 cells using Z-(Ac)Lys-AMC as subst...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of C-terminal FLAG/His-tagged recombinant human HDAC1 expressed in baculovirus infected Sf9 insect cells using Z-(Ac)Lys-AMC as substrate ...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM50525643(CHEMBL4437165)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of recombinant human full length C-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 cells using ZMAL as substrate incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833WFVPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM50509443(CHEMBL4587363)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of recombinant human full length C-terminal His/FLAG-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells using ZMAL as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8J5FPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM50239857(CHEMBL4070745)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibition of recombinant full length human C-terminal FLAG/His-tagged HDAC1 expressed in baculovirus infected sf9 cells using Z-(Ac)Lys-AMC as subst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SWDPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM50239856(CHEMBL2311793)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells Z-(Ac)Lys-AMC as substrate measur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SWDPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM50509442(CHEMBL4564332)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Inhibition of recombinant human full length C-terminal His/FLAG-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells using ZMAL as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8J5FPubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM50239819(CHEMBL4095934)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of full length human recombinant C-terminal His-tagged HDAC3/NcoR2 expressed in baculovirus infected Sf9 insect cells using Boc-Lys(epsilo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P125ZPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM50239832(CHEMBL4090647)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Inhibition of full length human recombinant C-terminal FLAG-tagged HDAC2 expressed in baculovirus infected Sf9 insect cells using Boc-Lys(epsilon-Ac)...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P125ZPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM50509452(CHEMBL4459617)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Inhibition of recombinant human full length C-terminal His/FLAG-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells using ZMAL as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8J5FPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM50239824(CHEMBL4069631)copy SMILEScopy InChI
Affinity DataIC50: 66nMAssay Description:Inhibition of full length human recombinant C-terminal FLAG-tagged HDAC2 expressed in baculovirus infected Sf9 insect cells using Boc-Lys(epsilon-Ac)...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P125ZPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM50239859(CHEMBL4088276)copy SMILEScopy InChI
Affinity DataIC50: 77nMAssay Description:Inhibition of recombinant full length human C-terminal FLAG/His-tagged HDAC1 expressed in baculovirus infected sf9 cells using Z-(Ac)Lys-AMC as subst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SWDPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM50525643(CHEMBL4437165)copy SMILEScopy InChI
Affinity DataIC50: 81nMAssay Description:Inhibition of recombinant human full length C-terminal Flag-tagged HDAC2 expressed in baculovirus infected Sf9 cells using ZMAL as substrate incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833WFVPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM50239819(CHEMBL4095934)copy SMILEScopy InChI
Affinity DataIC50: 84nMAssay Description:Inhibition of eel acetylcholinesterase (AChE) activity by 50% More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P125ZPubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM50525643(CHEMBL4437165)copy SMILEScopy InChI
Affinity DataIC50: 87nMAssay Description:Inhibition of recombinant human C-terminal GST/His-tagged HDAC3 (1 to 428 residues) co-expressed with human N-terminal GST-tagged NCOR2 (395 to 489 r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833WFVPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 89nMAssay Description:Inhibition of recombinant human full length C-terminal Flag/His-tagged HDAC1 expressed in baculovirus infected Sf9 cells using ZMAL as substrate incu...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM50239822(CHEMBL4080343)copy SMILEScopy InChI
Affinity DataIC50: 96nMAssay Description:Inhibition of C-terminal FLAG/His-tagged recombinant human HDAC1 expressed in baculovirus infected Sf9 insect cells using Z-(Ac)Lys-AMC as substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P125ZPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 102nMAssay Description:Inhibition of human full length N-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 insect cells ZMAL as substrate incubated for 90 min...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8J5FPubMedDrugBank
TargetHistone deacetylase 1(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM50509457(CHEMBL4460434)copy SMILEScopy InChI
Affinity DataIC50: 103nMAssay Description:Inhibition of recombinant human full length C-terminal His/FLAG-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells using ZMAL as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8J5FPubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 105nMAssay Description:Inhibition of recombinant human C-terminal GST/His-tagged HDAC3 (1 to 428 residues) co-expressed with human N-terminal GST-tagged NCOR2 (395 to 489 r...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833WFVPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM50239822(CHEMBL4080343)copy SMILEScopy InChI
Affinity DataIC50: 106nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human HDAC6 expressed in baculovirus infected Sf9 insect cells using Z-(Ac)Lys-AMC as substrate measu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P125ZPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 108nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells Z-(Ac)Lys-AMC as substrate measur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SWDPubMedDrugBank
TargetHistone deacetylase 6(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 108nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human HDAC6 expressed in baculovirus infected Sf9 insect cells using Z-(Ac)Lys-AMC as substrate measu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P125ZPubMedDrugBank
TargetHistone deacetylase(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM50509450(CHEMBL4474656)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of HDAC in human CAL27 cells using Boc-Lys(epsilon-Ac)-AMC as substrate preincubated for 18 hrs followed by substrate addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8J5FPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 111nMAssay Description:Inhibition of recombinant human full length C-terminal His/FLAG-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells using ZMAL as substra...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM50525642(CHEMBL4457698)copy SMILEScopy InChI
Affinity DataIC50: 132nMAssay Description:Inhibition of recombinant human full length C-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 cells using ZMAL as substrate incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833WFVPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM50239832(CHEMBL4090647)copy SMILEScopy InChI
Affinity DataIC50: 135nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human HDAC6 expressed in baculovirus infected Sf9 insect cells using Z-(Ac)Lys-AMC as substrate measu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P125ZPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 146nMAssay Description:Inhibition of recombinant human full length C-terminal FLAG-tagged HDAC2 expressed in baculovirus infected Sf9 insect cells using Boc-Lys(epsilon-ace...More data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM50239822(CHEMBL4080343)copy SMILEScopy InChI
Affinity DataIC50: 146nMAssay Description:Compound was tested for the binding affinity towards Nicotinic acetylcholine receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P125ZPubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM50509445(CHEMBL4578162)copy SMILEScopy InChI
Affinity DataIC50: 163nMAssay Description:Inhibition of human recombinant full length C-terminal His-tagged HDAC3 (1 to 428 residues)/N-terminal GST-tagged NCOR2 (395 to 489 residues) express...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8J5FPubMed
TargetHistone deacetylase(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM50509452(CHEMBL4459617)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of HDAC in human CAL27 cells using Boc-Lys(epsilon-Ac)-AMC as substrate preincubated for 18 hrs followed by substrate addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8J5FPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 183nMAssay Description:Inhibition of recombinant human full length C-terminal Flag-tagged HDAC2 expressed in baculovirus infected Sf9 cells using ZMAL as substrate incubate...More data for this Ligand-Target Pair
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