Compile Data Set for Download or QSAR
Found 182 with Last Name = 'king' and Initial = 'ch'
TargetMelanocortin receptor 4(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139046(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)copy SMILEScopy InChI
Affinity DataKi:  24nMAssay Description:Agonistic potency towards human melanocortin 4 receptor, determined by 50% maximum cAMP releaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5F21PubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139032(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)copy SMILEScopy InChI
Affinity DataKi:  27nMAssay Description:Agonistic potency towards human melanocortin 4 receptor, determined by 50% maximum cAMP releaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5F21PubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139027((R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...)copy SMILEScopy InChI
Affinity DataKi:  34nMAssay Description:Agonistic potency towards human melanocortin 4 receptor, determined by 50% maximum cAMP releaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5F21PubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139043(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)copy SMILEScopy InChI
Affinity DataKi:  35nMAssay Description:Binding affinity towards human melanocortin 4 receptor using [125I]NDP-alpha-MSH as a radioligand in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5F21PubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139028((R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...)copy SMILEScopy InChI
Affinity DataKi:  60nMAssay Description:Agonistic potency towards human melanocortin 4 receptor, determined by 50% maximum cAMP releaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5F21PubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139023(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)copy SMILEScopy InChI
Affinity DataKi:  110nMAssay Description:Agonistic potency towards human melanocortin 4 receptor, determined by 50% maximum cAMP releaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5F21PubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139029(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)copy SMILEScopy InChI
Affinity DataKi:  140nMAssay Description:Agonistic potency towards human melanocortin 4 receptor, determined by 50% maximum cAMP releaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5F21PubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139036(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)copy SMILEScopy InChI
Affinity DataKi:  170nMAssay Description:Binding affinity towards human melanocortin 4 receptor using [125I]NDP-alpha-MSH as a radioligand in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5F21PubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139045(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)copy SMILEScopy InChI
Affinity DataKi:  210nMAssay Description:Agonistic potency towards human melanocortin 4 receptor, determined by 50% maximum cAMP releaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5F21PubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50134496((R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...)copy SMILEScopy InChI
Affinity DataKi:  220nMAssay Description:Binding affinity towards human melanocortin 4 receptor using [125I]NDP-alpha-MSH as a radioligand in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5F21PubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139047(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)copy SMILEScopy InChI
Affinity DataKi:  230nMAssay Description:Agonistic potency towards human melanocortin 4 receptor, determined by 50% maximum cAMP releaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5F21PubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139048(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)copy SMILEScopy InChI
Affinity DataKi:  340nMAssay Description:Agonistic potency towards human melanocortin 4 receptor, determined by 50% maximum cAMP releaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5F21PubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139044(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)copy SMILEScopy InChI
Affinity DataKi:  350nMAssay Description:Agonistic potency towards human melanocortin 4 receptor, determined by 50% maximum cAMP releaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5F21PubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139040(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)copy SMILEScopy InChI
Affinity DataKi:  460nMAssay Description:Agonistic potency towards human melanocortin 4 receptor, determined by 50% maximum cAMP releaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5F21PubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139025(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)copy SMILEScopy InChI
Affinity DataKi:  530nMAssay Description:Binding affinity towards human melanocortin 4 receptor using [125I]NDP-alpha-MSH as a radioligand in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5F21PubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139022(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)copy SMILEScopy InChI
Affinity DataKi:  570nMAssay Description:Agonistic potency towards human melanocortin 4 receptor, determined by 50% maximum cAMP releaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5F21PubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139038(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)copy SMILEScopy InChI
Affinity DataKi:  630nMAssay Description:Binding affinity towards human melanocortin 4 receptor using [125I]NDP-alpha-MSH as a radioligand in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5F21PubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139031(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)copy SMILEScopy InChI
Affinity DataKi:  640nMAssay Description:Binding affinity towards human melanocortin 4 receptor using [125I]NDP-alpha-MSH as a radioligand in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5F21PubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139030(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)copy SMILEScopy InChI
Affinity DataKi:  640nMAssay Description:Agonistic potency towards human melanocortin 4 receptor, determined by 50% maximum cAMP releaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5F21PubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139023(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)copy SMILEScopy InChI
Affinity DataKi:  700nMAssay Description:Binding affinity towards human Melanocortin 5 receptor (MC5R) using [125I]NDP-alpha-MSH as a radioligand in membranes of HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5F21PubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139039(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)copy SMILEScopy InChI
Affinity DataKi:  720nMAssay Description:Agonistic potency towards human melanocortin 4 receptor, determined by 50% maximum cAMP releaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5F21PubMed
TargetMu-type opioid receptor(CALF)
Albany Molecular Research

Curated by ChEMBL
LigandPNGBDBM50086682((+)-18-Methoxycoronaridine hydrochloride | (+/-)-1...)copy SMILEScopy InChI
Affinity DataKi:  740nMAssay Description:Binding affinity against Opioid receptor mu 1 of calf cortex using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DTXPubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139042(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)copy SMILEScopy InChI
Affinity DataKi:  1.10E+3nMAssay Description:Binding affinity towards human melanocortin 4 receptor using [125I]NDP-alpha-MSH as a radioligand in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5F21PubMed
TargetMu-type opioid receptor(CALF)
Albany Molecular Research

Curated by ChEMBL
LigandPNGBDBM50086682((+)-18-Methoxycoronaridine hydrochloride | (+/-)-1...)copy SMILEScopy InChI
Affinity DataKi:  1.10E+3nMAssay Description:Binding affinity against Opioid receptor mu 1 of calf cortex using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DTXPubMed
TargetMu-type opioid receptor(CALF)
Albany Molecular Research

Curated by ChEMBL
LigandPNGBDBM50086682((+)-18-Methoxycoronaridine hydrochloride | (+/-)-1...)copy SMILEScopy InChI
Affinity DataKi:  1.10E+3nMAssay Description:Binding affinity against Opioid receptor mu 1 of calf cortex using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DTXPubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139041(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)copy SMILEScopy InChI
Affinity DataKi:  1.10E+3nMAssay Description:Agonistic potency towards human melanocortin 4 receptor, determined by 50% maximum cAMP releaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5F21PubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50134496((R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...)copy SMILEScopy InChI
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity towards human Melanocortin 5 receptor (MC5R) using [125I]NDP-alpha-MSH as a radioligand in membranes of HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5F21PubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139034(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)copy SMILEScopy InChI
Affinity DataKi:  1.30E+3nMAssay Description:Agonistic potency towards human melanocortin 4 receptor, determined by 50% maximum cAMP releaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5F21PubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139028((R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...)copy SMILEScopy InChI
Affinity DataKi:  1.40E+3nMAssay Description:Binding affinity towards human Melanocortin 5 receptor (MC5R) using [125I]NDP-alpha-MSH as a radioligand in membranes of HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5F21PubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139033(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)copy SMILEScopy InChI
Affinity DataKi:  1.70E+3nMAssay Description:Agonistic potency towards human melanocortin 4 receptor, determined by 50% maximum cAMP releaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5F21PubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139035(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)copy SMILEScopy InChI
Affinity DataKi:  1.70E+3nMAssay Description:Agonistic potency towards human melanocortin 4 receptor, determined by 50% maximum cAMP releaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5F21PubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139026(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)copy SMILEScopy InChI
Affinity DataKi:  1.90E+3nMAssay Description:Binding affinity towards human melanocortin 4 receptor using [125I]NDP-alpha-MSH as a radioligand in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5F21PubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139037(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)copy SMILEScopy InChI
Affinity DataKi:  2.40E+3nMAssay Description:Agonistic potency towards human melanocortin 4 receptor, determined by 50% maximum cAMP releaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5F21PubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Albany Molecular Research

Curated by ChEMBL
LigandPNGBDBM50086682((+)-18-Methoxycoronaridine hydrochloride | (+/-)-1...)copy SMILEScopy InChI
Affinity DataKi:  3.50E+3nMAssay Description:Binding affinity against Opioid receptor delta 1 of calf cortex using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DTXPubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139023(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)copy SMILEScopy InChI
Affinity DataKi:  3.60E+3nMAssay Description:Binding affinity towards human Melanocortin 3 receptor (MC3R) using [125I]NDP-alpha-MSH as a radioligand in membranes of HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5F21PubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Albany Molecular Research

Curated by ChEMBL
LigandPNGBDBM50086682((+)-18-Methoxycoronaridine hydrochloride | (+/-)-1...)copy SMILEScopy InChI
Affinity DataKi:  3.80E+3nMAssay Description:Binding affinity against Opioid receptor mu 1 of calf cortex using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DTXPubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139023(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)copy SMILEScopy InChI
Affinity DataKi:  4.00E+3nMAssay Description:Binding affinity towards human Melanocortin 1 receptor (MC1R) using [125I]NDP-alpha-MSH as a radioligand in membranes of HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5F21PubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Albany Molecular Research

Curated by ChEMBL
LigandPNGBDBM50086682((+)-18-Methoxycoronaridine hydrochloride | (+/-)-1...)copy SMILEScopy InChI
Affinity DataKi:  4.80E+3nMAssay Description:Binding affinity against Opioid receptor kappa 1 of calf cortex using [3H]-U-69,593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DTXPubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Albany Molecular Research

Curated by ChEMBL
LigandPNGBDBM50086682((+)-18-Methoxycoronaridine hydrochloride | (+/-)-1...)copy SMILEScopy InChI
Affinity DataKi:  5.10E+3nMAssay Description:Binding affinity against Opioid receptor kappa 1 of calf cortex using [3H]-U-69,593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DTXPubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Albany Molecular Research

Curated by ChEMBL
LigandPNGBDBM50086682((+)-18-Methoxycoronaridine hydrochloride | (+/-)-1...)copy SMILEScopy InChI
Affinity DataKi:  5.50E+3nMAssay Description:Binding affinity against Opioid receptor kappa 1 of calf cortex using [3H]-U-69,593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DTXPubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139024(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)copy SMILEScopy InChI
Affinity DataKi:  6.60E+3nMAssay Description:Binding affinity towards human melanocortin 4 receptor using [125I]NDP-alpha-MSH as a radioligand in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5F21PubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139028((R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...)copy SMILEScopy InChI
Affinity DataKi:  7.00E+3nMAssay Description:Binding affinity towards human Melanocortin 3 receptor (MC3R) using [125I]NDP-alpha-MSH as a radioligand in membranes of HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5F21PubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50134496((R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...)copy SMILEScopy InChI
Affinity DataKi:  8.80E+3nMAssay Description:Binding affinity towards human Melanocortin 3 receptor (MC3R) using [125I]NDP-alpha-MSH as a radioligand in membranes of HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5F21PubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50134496((R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...)copy SMILEScopy InChI
Affinity DataKi:  1.20E+4nMAssay Description:Binding affinity towards human Melanocortin 1 receptor (MC1R) using [125I]NDP-alpha-MSH as a radioligand in membranes of HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5F21PubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139028((R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...)copy SMILEScopy InChI
Affinity DataKi: >2.00E+4nMAssay Description:Binding affinity towards human Melanocortin 1 receptor (MC1R) using [125I]NDP-alpha-MSH as a radioligand in membranes of HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5F21PubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Albany Molecular Research

Curated by ChEMBL
LigandPNGBDBM50086682((+)-18-Methoxycoronaridine hydrochloride | (+/-)-1...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity against Opioid receptor kappa 1 of calf cortex using [3H]-U-69,593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3DTXPubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Lilly Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50184486(1-methyl-6-(2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of TGFbeta R1 induced transcriptional activation of p3TP-Lux in mink Mv1Lu lung cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40TS0PubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Lilly Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50184488(6-[2-(6-methyl-pyridin-2-yl)-5,6-dihydro-4H-pyrrol...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of TGFbeta R1 induced transcriptional activation of p3TP-Lux in mink Mv1Lu lung cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40TS0PubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Lilly Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50184483(1-methyl-6-[2-(6-methylpyridin-2-yl)-5,6-dihydro-4...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant human TGFbeta R1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40TS0PubMed
TargetTGF-beta receptor type-1 [4-503,T204D](Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM21506(Dihydropyrrolopyrazole, 15a | dimethyl[2-({4-[2-(p...)copy SMILEScopy InChI
Affinity DataIC50: 24nM EC50:  29nMpH: 7.5 T: 2°CAssay Description:The kinase activity was assayed by the autophosphorylation reaction of ALK5 (T204D) in the presence of 4 uM ATP and [33P]-gamma-ATP. After incubation...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G15Z4KPubMed
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