Compile Data Set for Download or QSAR
Found 14 with Last Name = 'brightwell' and Initial = 'ci'
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth Research (UK)

Curated by ChEMBL
LigandPNGBDBM50047471((S)-N-tert-butyl-3-(4-(2-methoxyphenyl)piperazin-1...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:In vitro binding affinity towards the 5-hydroxytryptamine 1A receptor was evaluatedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29W0DJHPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth Research (UK)

Curated by ChEMBL
LigandPNGBDBM50001859((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:In vitro binding affinity towards the 5-hydroxytryptamine 1A receptor was evaluatedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29W0DJHPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth Research (UK)

Curated by ChEMBL
LigandPNGBDBM50047472((R)-N-tert-Butyl-3-[4-(2-methoxy-phenyl)-piperazin...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:In vitro binding affinity towards the 5-hydroxytryptamine 1A receptor was evaluatedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29W0DJHPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth Research (UK)

Curated by ChEMBL
LigandPNGBDBM50001859((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 265nMAssay Description:In vitro binding affinity towards the dopamine receptor D2 at 10 e-6 MMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29W0DJHPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth Research (UK)

Curated by ChEMBL
LigandPNGBDBM50456023(CHEMBL289981)copy SMILEScopy InChI
Affinity DataIC50: 437nMAssay Description:In vitro binding affinity towards the 5-hydroxytryptamine 1A receptor was evaluatedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29W0DJHPubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Wyeth Research (UK)

Curated by ChEMBL
LigandPNGBDBM50001859((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro binding affinity towards the 5-hydroxytryptamine 1C receptor at 10 e-6 MMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29W0DJHPubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rattus norvegicus (Rat))
Wyeth Research (UK)

Curated by ChEMBL
LigandPNGBDBM50001859((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro binding affinity towards the noradrenergic beta receptor at 10 e-6 MMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29W0DJHPubMed
LigandPNGBDBM50001859((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro binding affinity towards the noradrenergic alpha-2 receptor at 10 e-6 MMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29W0DJHPubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Wyeth Research (UK)

Curated by ChEMBL
LigandPNGBDBM50001859((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro binding affinity towards the noradrenergic alpha-1 receptor at 10 e-6 MMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29W0DJHPubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Wyeth Research (UK)

Curated by ChEMBL
LigandPNGBDBM50047471((S)-N-tert-butyl-3-(4-(2-methoxyphenyl)piperazin-1...)copy SMILEScopy InChI
Affinity DataIC50: 1.39E+3nMAssay Description:In vitro binding affinity towards the 5-hydroxytryptamine 2 receptor at 10 e-6 MMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29W0DJHPubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Wyeth Research (UK)

Curated by ChEMBL
LigandPNGBDBM50047472((R)-N-tert-Butyl-3-[4-(2-methoxy-phenyl)-piperazin...)copy SMILEScopy InChI
Affinity DataIC50: 1.49E+3nMAssay Description:In vitro binding affinity towards the anor-adrenergic alpha-1 receptor at 10 e-6 MMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29W0DJHPubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Wyeth Research (UK)

Curated by ChEMBL
LigandPNGBDBM50047471((S)-N-tert-butyl-3-(4-(2-methoxyphenyl)piperazin-1...)copy SMILEScopy InChI
Affinity DataIC50: 1.88E+3nMAssay Description:In vitro binding affinity towards the alpha-1 receptor at 10 e-6 MMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29W0DJHPubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Wyeth Research (UK)

Curated by ChEMBL
LigandPNGBDBM50001859((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 2.15E+3nMAssay Description:In vitro binding affinity towards the 5-hydroxytryptamine 2 receptor at 10 e-6 MMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29W0DJHPubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Wyeth Research (UK)

Curated by ChEMBL
LigandPNGBDBM50456023(CHEMBL289981)copy SMILEScopy InChI
Affinity DataIC50: 2.78E+3nMAssay Description:In vitro binding affinity towards the noradrenergic alpha-1 receptor at 10 e-6 MMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29W0DJHPubMed