Compile Data Set for Download or QSAR
Found 3369 with Last Name = 'cohen' and Initial = 'cj'
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM642632(US20230416245, Compound 70)copy SMILES
Affinity DataKi:  0.133nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM642621(US20230416245, Compound 59)copy SMILES
Affinity DataKi:  0.230nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521576(CHEMBL4462278)copy SMILEScopy InChI
Affinity DataKi:  0.320nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM642624(US20230416245, Compound 62)copy SMILES
Affinity DataKi:  0.330nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521582(CHEMBL4543884)copy SMILEScopy InChI
Affinity DataKi:  0.510nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50466967(CHEMBL4282994)copy SMILEScopy InChI
Affinity DataKi:  0.530nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM642626(US20230416245, Compound 64)copy SMILES
Affinity DataKi:  0.640nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521579(CHEMBL4543422)copy SMILEScopy InChI
Affinity DataKi:  0.680nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM642625(US20230416245, Compound 63)copy SMILES
Affinity DataKi:  0.720nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521586(CHEMBL4473871)copy SMILEScopy InChI
Affinity DataKi:  0.760nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521571(CHEMBL4464990)copy SMILEScopy InChI
Affinity DataKi:  0.790nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521573(CHEMBL4519170)copy SMILEScopy InChI
Affinity DataKi:  0.850nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521569(CHEMBL4446868)copy SMILEScopy InChI
Affinity DataKi:  0.930nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521568(CHEMBL4444408)copy SMILEScopy InChI
Affinity DataKi:  0.970nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521577(CHEMBL4530176)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM642618(US20230416245, Compound 45)copy SMILES
Affinity DataKi:  1.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521585(CHEMBL4557850)copy SMILEScopy InChI
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521580(CHEMBL4474681)copy SMILEScopy InChI
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM642635(US20230416245, Compound 83)copy SMILES
Affinity DataKi:  1.62nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM642631(US20230416245, Compound 69)copy SMILES
Affinity DataKi:  1.68nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM642620(US20230416245, Compound 35)copy SMILES
Affinity DataKi:  1.70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521578(CHEMBL4444085)copy SMILEScopy InChI
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM642615(US20230416245, Compound 40)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM642636(US20230416245, Compound 90)copy SMILES
Affinity DataKi:  2.42nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM642639(US20230416245, Compound 93)copy SMILES
Affinity DataKi:  2.59nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521587(CHEMBL4569507)copy SMILEScopy InChI
Affinity DataKi:  2.90nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521575(CHEMBL4450910)copy SMILEScopy InChI
Affinity DataKi:  2.90nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM642627(US20230416245, Compound 65)copy SMILES
Affinity DataKi:  3.49nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521574(CHEMBL4455517)copy SMILEScopy InChI
Affinity DataKi:  3.90nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM642630(US20230416245, Compound 68)copy SMILES
Affinity DataKi:  4.75nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM642634(US20230416245, Compound 82)copy SMILES
Affinity DataKi:  4.77nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM642637(US20230416245, Compound 91)copy SMILES
Affinity DataKi:  5.10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM642623(US20230416245, Compound 61)copy SMILES
Affinity DataKi:  7.15nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521581(CHEMBL4462340)copy SMILEScopy InChI
Affinity DataKi:  18nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM642619(US20230416245, Compound 46)copy SMILES
Affinity DataKi:  21.3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM642638(US20230416245, Compound 92)copy SMILES
Affinity DataKi:  26.8nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM642617(US20230416245, Compound 44)copy SMILES
Affinity DataKi:  28.4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521570(CHEMBL4539134)copy SMILEScopy InChI
Affinity DataKi:  72nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM642629(US20230416245, Compound 67)copy SMILES
Affinity DataKi:  94.4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM642628(US20230416245, Compound 66)copy SMILES
Affinity DataKi:  126nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50166790(CHEMBL364912 | {2-[2-(4-Chloro-phenyl)-thiazol-4-y...)copy SMILEScopy InChI
Affinity DataKi:  140nMAssay Description:In vitro inhibitory concentration against Na v1.7 channel electrophysiology in inactivated state expressed in HEK293 cells using Voltage/Ion Probe Re...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X929TBPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50166787(CHEMBL195235 | {2-[2-(4-Chloro-phenyl)-thiazol-4-y...)copy SMILEScopy InChI
Affinity DataKi:  160nMAssay Description:In vitro inhibitory concentration against Na v1.7 channel electrophysiology in inactivated state expressed in HEK293 cells using Voltage/Ion Probe Re...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X929TBPubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50568138(CHEMBL4854735)copy SMILES
Affinity DataKi:  370nMAssay Description:Displacement of [3H]BNZA from Nav1.5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8J7BPubMed
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM642633(US20230416245, Compound 71)copy SMILES
Affinity DataKi:  456nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521583(CHEMBL4556147)copy SMILEScopy InChI
Affinity DataKi:  509nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521584(CHEMBL4452003)copy SMILEScopy InChI
Affinity DataKi: >700nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521572(CHEMBL4585581)copy SMILEScopy InChI
Affinity DataKi: >700nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50568135(CHEMBL4849813)copy SMILES
Affinity DataKi:  2.02E+3nMAssay Description:Displacement of [3H]BNZA from Nav1.5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8J7BPubMed
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM642622(US20230416245, Compound 60)copy SMILES
Affinity DataKi: >9.40E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetSodium channel protein type 9 subunit alpha(Mus musculus)
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50169425(CHEMBL3341983 | US9481677, 44)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of Nav1.7 channel in mouse CAD cells by whole-cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J1052WPubMed
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