Compile Data Set for Download or QSAR
Found 71 with Last Name = 'darienzo' and Initial = 'cj'
TargetAndrogen receptor(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50205111(3-chloro-4-((7R,7aS)-7-hydroxy-1,3-dioxo-tetrahydr...)copy SMILEScopy InChI
Affinity DataKi:  0.700nMAssay Description:Binding affinity to human ARMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RN1PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50205116(2-bromo-4-((7R,7aS)-7-hydroxy-1,3-dioxo-tetrahydro...)copy SMILEScopy InChI
Affinity DataKi:  1.20nMAssay Description:Binding affinity to human ARMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RN1PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50205114(2-fluoro-4-((7R,7aS)-7-hydroxy-1,3-dioxo-tetrahydr...)copy SMILEScopy InChI
Affinity DataKi:  1.30nMAssay Description:Binding affinity to human ARMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RN1PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50205096(2-chloro-4-((7R,7aS)-7-hydroxy-1,3-dioxo-tetrahydr...)copy SMILEScopy InChI
Affinity DataKi:  1.5nMAssay Description:Binding affinity to human ARMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RN1PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM18173(4-[(7R,7aS)-7-hydroxy-1,3-dioxo-hexahydro-1H-pyrro...)copy SMILEScopy InChI
Affinity DataKi:  2.10nMAssay Description:Binding affinity to human ARMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50205100(4-((7R,7aS)-7-hydroxy-1,3-dioxo-tetrahydro-1H-pyrr...)copy SMILEScopy InChI
Affinity DataKi:  2.90nMAssay Description:Binding affinity to human ARMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RN1PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50205113(2-chloro-3-fluoro-4-((7R,7aS)-7-hydroxy-1,3-dioxo-...)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Binding affinity to human ARMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RN1PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM18171(4-[(7R,7aS)-7-hydroxy-1,3-dioxo-hexahydro-1H-pyrro...)copy SMILEScopy InChI
Affinity DataKi:  3.20nMAssay Description:Binding affinity to human ARMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50205102(3-ethyl-4-((7R,7aS)-7-hydroxy-1,3-dioxo-tetrahydro...)copy SMILEScopy InChI
Affinity DataKi:  3.30nMAssay Description:Binding affinity to human ARMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RN1PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50205103(4-((7R,7aS)-7-hydroxy-1,3-dioxo-tetrahydro-1H-pyrr...)copy SMILEScopy InChI
Affinity DataKi:  3.70nMAssay Description:Binding affinity to human ARMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RN1PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50205104(2,3-difluoro-4-((7R,7aS)-7-hydroxy-1,3-dioxo-tetra...)copy SMILEScopy InChI
Affinity DataKi:  4.30nMAssay Description:Binding affinity to human ARMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RN1PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50205098(4-((7R,7aS)-7-hydroxy-1,3-dioxo-tetrahydro-1H-pyrr...)copy SMILEScopy InChI
Affinity DataKi:  4.5nMAssay Description:Binding affinity to human ARMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RN1PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50205107(3-chloro-4-((7R,7aS)-7-hydroxy-1,3-dioxo-tetrahydr...)copy SMILEScopy InChI
Affinity DataKi:  6.10nMAssay Description:Binding affinity to human ARMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RN1PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50205101(4-((7R,7aS)-7-hydroxy-1,3-dioxo-tetrahydro-1H-pyrr...)copy SMILEScopy InChI
Affinity DataKi:  7.80nMAssay Description:Binding affinity to human ARMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RN1PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50205110(4-((7R,7aS)-7-hydroxy-1,3-dioxo-tetrahydro-1H-pyrr...)copy SMILEScopy InChI
Affinity DataKi:  7.90nMAssay Description:Binding affinity to human ARMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RN1PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50205112(4-((7R,7aS)-7-hydroxy-1,3-dioxo-tetrahydro-1H-pyrr...)copy SMILEScopy InChI
Affinity DataKi:  8nMAssay Description:Binding affinity to human ARMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RN1PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50205099(4-((7R,7aS)-7-hydroxy-1,3-dioxo-tetrahydro-1H-pyrr...)copy SMILEScopy InChI
Affinity DataKi:  8.10nMAssay Description:Binding affinity to human ARMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RN1PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50205115(4-((7R,7aS)-7-hydroxy-1,3-dioxo-tetrahydro-1H-pyrr...)copy SMILEScopy InChI
Affinity DataKi:  8.5nMAssay Description:Binding affinity to human ARMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RN1PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50205097(3-ethyl-4-((7R,7aS)-7-hydroxy-1,3-dioxo-tetrahydro...)copy SMILEScopy InChI
Affinity DataKi:  14nMAssay Description:Binding affinity to human ARMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RN1PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50205108(8-((7R,7aS)-7-hydroxy-1,3-dioxo-tetrahydro-1H-pyrr...)copy SMILEScopy InChI
Affinity DataKi:  21nMAssay Description:Binding affinity to human ARMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RN1PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50205106(4-((7R,7aS)-7-hydroxy-1,3-dioxo-tetrahydro-1H-pyrr...)copy SMILEScopy InChI
Affinity DataKi:  24nMAssay Description:Binding affinity to human ARMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RN1PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50205105(4-((7R,7aS)-7-hydroxy-1,3-dioxo-tetrahydro-1H-pyrr...)copy SMILEScopy InChI
Affinity DataKi:  34nMAssay Description:Binding affinity to human ARMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RN1PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50205109(5-((7R,7aS)-7-hydroxy-1,3-dioxo-tetrahydro-pyrrolo...)copy SMILEScopy InChI
Affinity DataKi:  48nMAssay Description:Binding affinity to human ARMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RN1PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb Company

LigandPNGBDBM22158((3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[methyl(1-methy...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nM EC50:  1.40nMpH: 7.0 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8JB2PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb Company

LigandPNGBDBM22160(pyrazole compound, 14a | sodium 5-({5-[(1E,3S,5R)-...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nM EC50:  13.7nMpH: 7.0 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8JB2PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb Company

LigandPNGBDBM22157((3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[(1-methyl-1H-1...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nM EC50:  1.5nMpH: 7.0 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8JB2PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb Company

LigandPNGBDBM22163(BMS-644950 | sodium (3R,5S,6E)-7-[4-(4-fluoropheny...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nM EC50:  3.95nMpH: 7.0 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8JB2PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb Company

LigandPNGBDBM22154((3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[(1-methyl-1H-p...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nM EC50:  3.70nMpH: 7.0 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8JB2PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb Company

LigandPNGBDBM22152((3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[N-(1-methyl-1H...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nM EC50:  5.40nMpH: 7.0 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8JB2PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb Company

LigandPNGBDBM22147((3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(1,2-oxazol-3-y...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nM EC50:  1.40nMpH: 7.0 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8JB2PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb Company

LigandPNGBDBM22150((3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[(1-methyl-1H-p...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nM EC50:  1.30nMpH: 7.0 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8JB2PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb Company

LigandPNGBDBM22151((3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[methyl(1-methy...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nM EC50:  2.5nMpH: 7.0 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8JB2PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb Company

LigandPNGBDBM22155((3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[methyl(1-methy...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nM EC50:  1.20nMpH: 7.0 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8JB2PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb Company

LigandPNGBDBM22162(sodium (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[N-(1-me...)copy SMILEScopy InChI
Affinity DataIC50: 2.90nM EC50:  7.5nMpH: 7.0 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8JB2PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb Company

LigandPNGBDBM22161(sodium (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[(1-meth...)copy SMILEScopy InChI
Affinity DataIC50: 3nM EC50:  3.70nMpH: 7.0 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8JB2PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb Company

LigandPNGBDBM18372((3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethan...)copy SMILEScopy InChI
Affinity DataIC50: 3.10nM EC50:  0.600nMpH: 7.0 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb Company

LigandPNGBDBM22156((3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[N-(1-methyl-1H...)copy SMILEScopy InChI
Affinity DataIC50: 3.70nM EC50:  7.70nMpH: 7.0 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8JB2PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb Company

LigandPNGBDBM22159((3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[N-(1-methyl-1H...)copy SMILEScopy InChI
Affinity DataIC50: 4.20nM EC50:  1nMpH: 7.0 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8JB2PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb Company

LigandPNGBDBM18375((3R,5R)-7-[(1S,2S,6R,8S,8aR)-8-[(2,2-dimethylbutan...)copy SMILEScopy InChI
Affinity DataIC50: 4.30nM EC50:  6.20nMpH: 7.0 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb Company

LigandPNGBDBM22164((3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylca...)copy SMILEScopy InChI
Affinity DataIC50: 6.20nM EC50:  2.5nMpH: 7.0 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb Company

LigandPNGBDBM22146((3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[(5-phenyl-1,2,...)copy SMILEScopy InChI
Affinity DataIC50: 6.90nM EC50:  7.70nMpH: 7.0 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8JB2PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb Company

LigandPNGBDBM22148((3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[methyl(1,2-oxa...)copy SMILEScopy InChI
Affinity DataIC50: 7nM EC50:  9nMpH: 7.0 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8JB2PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb Company

LigandPNGBDBM18376((3R,5S,6E)-7-[4-(4-fluorophenyl)-5-(methoxymethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 9.80nM EC50:  2.30nMpH: 7.0 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb Company

LigandPNGBDBM22153((3R,5S,6E)-7-{2-[(3-tert-butyl-1-methyl-1H-pyrazol...)copy SMILEScopy InChI
Affinity DataIC50: 12.4nM EC50:  1.90nMpH: 7.0 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8JB2PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb Company

LigandPNGBDBM20688((3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-...)copy SMILEScopy InChI
Affinity DataIC50: 31.6nM EC50:  29nMpH: 7.0 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8JB2PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb Company

LigandPNGBDBM22149((3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[N-(1,2-oxazol-...)copy SMILEScopy InChI
Affinity DataIC50: 33nM EC50:  5.5nMpH: 7.0 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8JB2PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50205097(3-ethyl-4-((7R,7aS)-7-hydroxy-1,3-dioxo-tetrahydro...)copy SMILEScopy InChI
Affinity DataEC50:  79nMAssay Description:Agonist activity at human ARMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RN1PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50205105(4-((7R,7aS)-7-hydroxy-1,3-dioxo-tetrahydro-1H-pyrr...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human ARMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RN1PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM18171(4-[(7R,7aS)-7-hydroxy-1,3-dioxo-hexahydro-1H-pyrro...)copy SMILEScopy InChI
Affinity DataEC50:  2.30nMAssay Description:Agonist activity at human ARMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50205104(2,3-difluoro-4-((7R,7aS)-7-hydroxy-1,3-dioxo-tetra...)copy SMILEScopy InChI
Affinity DataEC50:  47nMAssay Description:Agonist activity at human ARMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RN1PubMed
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