TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataKi: 1.00E+3nMAssay Description:Competitive inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMpH: 7.0 T: 2°CAssay Description:The one-point inhibition percentages were determined for human LOX inhibitors by following the formation of the conjugated diene product at 234 nm (&...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMpH: 7.0 T: 2°CAssay Description:The one-point inhibition percentages were determined for human LOX inhibitors by following the formation of the conjugated diene product at 234 nm (&...More data for this Ligand-Target Pair
Affinity DataIC50: 520nMpH: 7.0 T: 2°CAssay Description:The one-point inhibition percentages were determined for human LOX inhibitors by following the formation of the conjugated diene product at 234 nm (&...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: 810nMAssay Description:Inhibition of human 12/15-LOX expressed in HEK293 cells after 30 mins by microplate reader analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMpH: 7.0 T: 2°CAssay Description:The one-point inhibition percentages were determined for human LOX inhibitors by following the formation of the conjugated diene product at 234 nm (&...More data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMpH: 7.0 T: 2°CAssay Description:The one-point inhibition percentages were determined for human LOX inhibitors by following the formation of the conjugated diene product at 234 nm (&...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10E+3nMT: 2°CAssay Description:Briefly, 3 uL of enzyme (approximately 20 nM LoxA, final concentration) or buffer (no-enzyme control) was dispensed into 1536-well Greiner black clea...More data for this Ligand-Target Pair
Affinity DataIC50: 4.50E+3nMT: 2°CAssay Description:Briefly, 3 uL of enzyme (approximately 20 nM LoxA, final concentration) or buffer (no-enzyme control) was dispensed into 1536-well Greiner black clea...More data for this Ligand-Target Pair
Affinity DataIC50: 5.80E+3nMT: 2°CAssay Description:Briefly, 3 uL of enzyme (approximately 20 nM LoxA, final concentration) or buffer (no-enzyme control) was dispensed into 1536-well Greiner black clea...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 6.70E+3nMT: 2°CAssay Description:Briefly, 3 uL of enzyme (approximately 20 nM LoxA, final concentration) or buffer (no-enzyme control) was dispensed into 1536-well Greiner black clea...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMT: 2°CAssay Description:Briefly, 3 uL of enzyme (approximately 20 nM LoxA, final concentration) or buffer (no-enzyme control) was dispensed into 1536-well Greiner black clea...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.01E+4nMT: 2°CAssay Description:Briefly, 3 uL of enzyme (approximately 20 nM LoxA, final concentration) or buffer (no-enzyme control) was dispensed into 1536-well Greiner black clea...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.14E+4nMT: 2°CAssay Description:Briefly, 3 uL of enzyme (approximately 20 nM LoxA, final concentration) or buffer (no-enzyme control) was dispensed into 1536-well Greiner black clea...More data for this Ligand-Target Pair
Affinity DataIC50: 1.31E+4nMT: 2°CAssay Description:Briefly, 3 uL of enzyme (approximately 20 nM LoxA, final concentration) or buffer (no-enzyme control) was dispensed into 1536-well Greiner black clea...More data for this Ligand-Target Pair
Affinity DataIC50: 1.38E+4nMT: 2°CAssay Description:Briefly, 3 uL of enzyme (approximately 20 nM LoxA, final concentration) or buffer (no-enzyme control) was dispensed into 1536-well Greiner black clea...More data for this Ligand-Target Pair
Affinity DataIC50: 1.62E+4nMT: 2°CAssay Description:Briefly, 3 uL of enzyme (approximately 20 nM LoxA, final concentration) or buffer (no-enzyme control) was dispensed into 1536-well Greiner black clea...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Homo sapiens (Human))
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human 15-LOX-2 using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human 12-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human COX-2 by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair