Compile Data Set for Download or QSAR
Found 47 with Last Name = 'freedman' and Initial = 'cj'
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM56150((6E)-4-methyl-6-[5-(2-methylphenyl)-1,2-dihydropyr...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMAssay Description:Competitive inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7K44PubMed
TargetArachidonate 15-lipoxygenase(Pseudomonas aeruginosa)
University of California, Santa Cruz

LigandPNGBDBM50329323(4-(5-(Naphthalen-1-yl)-1,3,4-oxadiazol-2-ylthio)bu...)copy SMILEScopy InChI
Affinity DataIC50: 10nMpH: 7.0 T: 2°CAssay Description:The one-point inhibition percentages were determined for human LOX inhibitors by following the formation of the conjugated diene product at 234 nm (&...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZXTPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM79800(5-(methylamino)-2-(1-naphthalenyl)-4-oxazolecarbon...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7K44PubMed
TargetArachidonate 15-lipoxygenase(Pseudomonas aeruginosa)
University of California, Santa Cruz

LigandPNGBDBM32020(4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyro...)copy SMILEScopy InChI
Affinity DataIC50: 500nMpH: 7.0 T: 2°CAssay Description:The one-point inhibition percentages were determined for human LOX inhibitors by following the formation of the conjugated diene product at 234 nm (&...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZXTPubMed
TargetArachidonate 15-lipoxygenase(Pseudomonas aeruginosa)
University of California, Santa Cruz

LigandPNGBDBM190652(LOX inhibitor, 13 | PT171)copy SMILEScopy InChI
Affinity DataIC50: 520nMpH: 7.0 T: 2°CAssay Description:The one-point inhibition percentages were determined for human LOX inhibitors by following the formation of the conjugated diene product at 234 nm (&...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZXTPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50208823(6,11-dihydrothiochromeno[4,3-b]indole | CHEMBL1809...)copy SMILEScopy InChI
Affinity DataIC50: 810nMAssay Description:Inhibition of human 12/15-LOX expressed in HEK293 cells after 30 mins by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7K44PubMed
TargetArachidonate 15-lipoxygenase(Pseudomonas aeruginosa)
University of California, Santa Cruz

LigandPNGBDBM190651(LOX inhibitor, 5 | PT113)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMpH: 7.0 T: 2°CAssay Description:The one-point inhibition percentages were determined for human LOX inhibitors by following the formation of the conjugated diene product at 234 nm (&...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZXTPubMed
TargetArachidonate 15-lipoxygenase(Pseudomonas aeruginosa)
University of California, Santa Cruz

LigandPNGBDBM190650(LOX inhibitor, MLS000545091 | PT91)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMpH: 7.0 T: 2°CAssay Description:The one-point inhibition percentages were determined for human LOX inhibitors by following the formation of the conjugated diene product at 234 nm (&...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZXTPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM56150((6E)-4-methyl-6-[5-(2-methylphenyl)-1,2-dihydropyr...)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7K44PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM49247((6Z)-6-[5-(2-chlorophenyl)-1,2-dihydropyrazol-3-yl...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7K44PubMed
TargetArachidonate 15-lipoxygenase(Pseudomonas aeruginosa)
University of California, Santa Cruz

LigandPNGBDBM26948(8-[4,4-bis(4-fluorophenyl)butyl]-1-phenyl-1,3,8-tr...)copy SMILEScopy InChI
Affinity DataIC50: 4.10E+3nMT: 2°CAssay Description:Briefly, 3 uL of enzyme (approximately 20 nM LoxA, final concentration) or buffer (no-enzyme control) was dispensed into 1536-well Greiner black clea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZXTPubMed
TargetArachidonate 15-lipoxygenase(Pseudomonas aeruginosa)
University of California, Santa Cruz

LigandPNGBDBM50017702(1-(bis(4-fluorophenyl)methyl)-4-cinnamylpiperazine...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+3nMT: 2°CAssay Description:Briefly, 3 uL of enzyme (approximately 20 nM LoxA, final concentration) or buffer (no-enzyme control) was dispensed into 1536-well Greiner black clea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZXTPubMed
TargetArachidonate 15-lipoxygenase(Pseudomonas aeruginosa)
University of California, Santa Cruz

LigandPNGBDBM50334150(1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 5.80E+3nMT: 2°CAssay Description:Briefly, 3 uL of enzyme (approximately 20 nM LoxA, final concentration) or buffer (no-enzyme control) was dispensed into 1536-well Greiner black clea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZXTPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50148015(CHEMBL1540577)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7K44PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50187067(2-(5-(2-chlorophenyl)-1H-pyrazol-3-yl)-4-methoxyph...)copy SMILEScopy InChI
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7K44PubMed
TargetArachidonate 15-lipoxygenase(Pseudomonas aeruginosa)
University of California, Santa Cruz

LigandPNGBDBM20607((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...)copy SMILEScopy InChI
Affinity DataIC50: 6.70E+3nMT: 2°CAssay Description:Briefly, 3 uL of enzyme (approximately 20 nM LoxA, final concentration) or buffer (no-enzyme control) was dispensed into 1536-well Greiner black clea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZXTPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50148017(CHEMBL1353771)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7K44PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM57040((6E)-6-[5-(3-bromophenyl)-1,2-dihydropyrazol-3-yli...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7K44PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50148019(CHEMBL1604272)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7K44PubMed
TargetArachidonate 15-lipoxygenase(Pseudomonas aeruginosa)
University of California, Santa Cruz

LigandPNGBDBM22165(1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMT: 2°CAssay Description:Briefly, 3 uL of enzyme (approximately 20 nM LoxA, final concentration) or buffer (no-enzyme control) was dispensed into 1536-well Greiner black clea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZXTPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50148023(CHEMBL1448722)copy SMILEScopy InChI
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7K44PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM78048((6E)-6-[5-(3-fluorophenyl)-1,2-dihydropyrazol-3-yl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7K44PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50148018(CHEMBL1372333)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7K44PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM49390((6Z)-3-methyl-6-[5-(2-methylphenyl)-1,2-dihydropyr...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7K44PubMed
TargetArachidonate 15-lipoxygenase(Pseudomonas aeruginosa)
University of California, Santa Cruz

LigandPNGBDBM22873(1-(4-tert-butylphenyl)-4-[4-(diphenylmethoxy)piper...)copy SMILEScopy InChI
Affinity DataIC50: 1.01E+4nMT: 2°CAssay Description:Briefly, 3 uL of enzyme (approximately 20 nM LoxA, final concentration) or buffer (no-enzyme control) was dispensed into 1536-well Greiner black clea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZXTPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50148014(CHEMBL1370300)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7K44PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM114790((6Z)-6-[5-(4-fluorophenyl)-1,2-dihydropyrazol-3-yl...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7K44PubMed
TargetArachidonate 15-lipoxygenase(Pseudomonas aeruginosa)
University of California, Santa Cruz

LigandPNGBDBM21383(6-[4-(2-phenylphenyl)piperazin-1-yl]-N-(1,2,3,4-te...)copy SMILEScopy InChI
Affinity DataIC50: 1.14E+4nMT: 2°CAssay Description:Briefly, 3 uL of enzyme (approximately 20 nM LoxA, final concentration) or buffer (no-enzyme control) was dispensed into 1536-well Greiner black clea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZXTPubMed
TargetArachidonate 15-lipoxygenase(Pseudomonas aeruginosa)
University of California, Santa Cruz

LigandPNGBDBM79021((1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-te...)copy SMILEScopy InChI
Affinity DataIC50: 1.31E+4nMT: 2°CAssay Description:Briefly, 3 uL of enzyme (approximately 20 nM LoxA, final concentration) or buffer (no-enzyme control) was dispensed into 1536-well Greiner black clea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZXTPubMed
TargetArachidonate 15-lipoxygenase(Pseudomonas aeruginosa)
University of California, Santa Cruz

LigandPNGBDBM50017712((-)-reserpine | (3beta,16beta,17alpha,18beta,20alp...)copy SMILEScopy InChI
Affinity DataIC50: 1.38E+4nMT: 2°CAssay Description:Briefly, 3 uL of enzyme (approximately 20 nM LoxA, final concentration) or buffer (no-enzyme control) was dispensed into 1536-well Greiner black clea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZXTPubMed
TargetArachidonate 15-lipoxygenase(Pseudomonas aeruginosa)
University of California, Santa Cruz

LigandPNGBDBM50092228(4-Amino-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrim...)copy SMILEScopy InChI
Affinity DataIC50: 1.62E+4nMT: 2°CAssay Description:Briefly, 3 uL of enzyme (approximately 20 nM LoxA, final concentration) or buffer (no-enzyme control) was dispensed into 1536-well Greiner black clea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZXTPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50148013(CHEMBL1520849)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7K44PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM49265((6Z)-6-[5-(3-fluorophenyl)-1,2-dihydropyrazol-3-yl...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7K44PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50148016(CHEMBL1718182)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7K44PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM59267((5E)-5-(3-methyl-6-oxidanylidene-cyclohexa-2,4-die...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7K44PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50148021(CHEMBL1736078)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7K44PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM56150((6E)-4-methyl-6-[5-(2-methylphenyl)-1,2-dihydropyr...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human 15-LOX-2 using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7K44PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM56150((6E)-4-methyl-6-[5-(2-methylphenyl)-1,2-dihydropyr...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human 12-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7K44PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50147966(CHEMBL1344000)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7K44PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50147981(CHEMBL1546898)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7K44PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50147986(CHEMBL1442717)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7K44PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50148011(CHEMBL1328952)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7K44PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM24679((6Z)-6-(3-pyrazolin-3-ylidene)cyclohexa-2,4-dien-1...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7K44PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50148009(CHEMBL375966)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7K44PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50148010(CHEMBL584668 | GNF-Pf-4068)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7K44PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM56150((6E)-4-methyl-6-[5-(2-methylphenyl)-1,2-dihydropyr...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7K44PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM56150((6E)-4-methyl-6-[5-(2-methylphenyl)-1,2-dihydropyr...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human COX-2 by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7K44PubMed