Compile Data Set for Download or QSAR
Found 12 with Last Name = 'kirk' and Initial = 'cj'
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix, Inc.

Curated by ChEMBL
LigandPNGBDBM50277781((2S)-2-[(2S)-2-[(5-ethoxy-1,2-oxazol-3-yl)formamid...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1KS0PubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix, Inc.

Curated by ChEMBL
LigandPNGBDBM50069989((R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxa...)copy SMILEScopy InChI
Affinity DataIC50: 8.10nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1KS0PubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix, Inc.

Curated by ChEMBL
LigandPNGBDBM50277889(CARFILZOMIB | CHEMBL451887)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1KS0PubMedDrugBank
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix, Inc.

Curated by ChEMBL
LigandPNGBDBM50277779(CHEMBL484003 | N-((S)-3-methoxy-1-((S)-3-methoxy-1...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1KS0PubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix, Inc.

Curated by ChEMBL
LigandPNGBDBM50277815(3-methoxy-N-((S)-3-methoxy-1-((S)-3-methoxy-1-((S)...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1KS0PubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix, Inc.

Curated by ChEMBL
LigandPNGBDBM50277816(3-methoxy-N-((S)-3-methoxy-1-((S)-3-methoxy-1-((S)...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1KS0PubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix, Inc.

Curated by ChEMBL
LigandPNGBDBM50277780(5-ethoxy-N-((S)-3-methoxy-1-((S)-3-methoxy-1-((S)-...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1KS0PubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix, Inc.

Curated by ChEMBL
LigandPNGBDBM50277818(2-Me-5-thiazole-Ser(OMe)-Ser(OMe)-Phe-ketoepoxide ...)copy SMILEScopy InChI
Affinity DataIC50: 82nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1KS0PubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix, Inc.

Curated by ChEMBL
LigandPNGBDBM50277778(CHEMBL484002 | N-((S)-3-methoxy-1-((S)-3-methoxy-1...)copy SMILEScopy InChI
Affinity DataIC50: 93nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1KS0PubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix, Inc.

Curated by ChEMBL
LigandPNGBDBM50277733((2S)-3-methoxy-2-[(2S)-3-methoxy-2-[(5-methyl-1,2-...)copy SMILEScopy InChI
Affinity DataIC50: 238nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1KS0PubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix, Inc.

Curated by ChEMBL
LigandPNGBDBM50277734(CHEMBL484157 | N-((S)-3-methoxy-1-((S)-3-methoxy-1...)copy SMILEScopy InChI
Affinity DataIC50: 607nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1KS0PubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix, Inc.

Curated by ChEMBL
LigandPNGBDBM50277817(CHEMBL483740 | N-((S)-3-methoxy-1-((S)-3-methoxy-1...)copy SMILEScopy InChI
Affinity DataIC50: 784nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1KS0PubMed