Compile Data Set for Download or QSAR
Found 171 with Last Name = 'dean' and Initial = 'cl'
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6027(N-(4-{[3-Ethyl-4-oxo-1-(2,4,6-trichlorophenyl)-4,5...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6029(2-Amino-N-(4-{[3-ethyl-4-oxo-1-(2,4,6-trichlorophe...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6025(3-Ethyl-6-(3-hydroxybenzyl)-1-(2,4,6-trichlorophen...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6011(6-(4-Aminobenzyl)-3-ethyl-1-(2,4,6-trichlorophenyl...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6028(2-(tert-Butoxycarbonylamino)-N-(4-{[3-ethyl-4-oxo-...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6012(3-Ethyl-6-(4-methoxybenzyl)-1-(2,4,6-trichlorophen...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6013(3-Ethyl-6-(4-hydroxybenzyl)-1-(2,4,6-trichlorophen...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6009(3-Ethyl-6-(pyrid-3-ylmethyl)-1-(2,4,6-trichlorophe...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6030(2-(Dimethylamino)-N-(4-{[3-ethyl-4-oxo-1-(2,4,6-tr...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6004(6-(3-Amino-2-methylbenzyl)-3-ethyl-1-(2,4,6-trichl...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6023(3-Ethyl-6-(3-hydroxy-4-methoxybenzyl)-1-(2,4,6-tri...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6021(6-(3,4-Dihydroxybenzyl)-3-ethyl-1-(2,4,6-trichloro...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6022(6-(3,5-Dihydroxybenzyl)-3-ethyl-1-(2,4,6-trichloro...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6015(6-(4-(N,N-Dimethylamino)benzyl)-3-ethyl-1-(2,4,6-t...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6024(3-Ethyl-6-(3-hydroxy-4-methylbenzyl)-1-(2,4,6-tric...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6023(3-Ethyl-6-(3-hydroxy-4-methoxybenzyl)-1-(2,4,6-tri...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM5998(6-Benzyl-3-ethyl-1-(2,4,6-trichlorophenyl)-4,5-dih...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6002(3-Ethyl-6-(2-(hydroxymethyl)benzyl)-1-(2,4,6-trich...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6018(3-Ethyl-6-(4-hydroxy-3-methylbenzyl)-1-(2,4,6-tric...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6007(3-Ethyl-6-(3-methoxybenzyl)-1-(2,4,6-trichlorophen...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6027(N-(4-{[3-Ethyl-4-oxo-1-(2,4,6-trichlorophenyl)-4,5...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6010(3-Ethyl-6-(pyrid-4-ylmethyl)-1-(2,4,6-trichlorophe...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6005(3-Ethyl-6-(3-methylbenzyl)-1-(2,4,6-trichloropheny...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6008(6-(3-Aminobenzyl)-3-ethyl-1-(2,4,6-trichlorophenyl...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6021(6-(3,4-Dihydroxybenzyl)-3-ethyl-1-(2,4,6-trichloro...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM5999(3-(Methylthio)-6-benzyl-1-(2,4,6-trichlorophenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6014(6-(4-Bromobenzyl)-3-ethyl-1-(2,4,6-trichlorophenyl...)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6022(6-(3,5-Dihydroxybenzyl)-3-ethyl-1-(2,4,6-trichloro...)copy SMILEScopy InChI
Affinity DataIC50: 59nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6016(3-Ethyl-6-(4-methoxy-3-methylbenzyl)-1-(2,4,6-tric...)copy SMILEScopy InChI
Affinity DataIC50: 67nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6025(3-Ethyl-6-(3-hydroxybenzyl)-1-(2,4,6-trichlorophen...)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6029(2-Amino-N-(4-{[3-ethyl-4-oxo-1-(2,4,6-trichlorophe...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6019(3-Ethyl-6-(4-hydroxy-3-methoxybenzyl)-1-(2,4,6-tri...)copy SMILEScopy InChI
Affinity DataIC50: 76nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6024(3-Ethyl-6-(3-hydroxy-4-methylbenzyl)-1-(2,4,6-tric...)copy SMILEScopy InChI
Affinity DataIC50: 88nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM5977(3, 6-Diethyl-1-(2,4,6-trichlorophenyl)-4,5-dihydro...)copy SMILEScopy InChI
Affinity DataIC50: 96nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6030(2-(Dimethylamino)-N-(4-{[3-ethyl-4-oxo-1-(2,4,6-tr...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6013(3-Ethyl-6-(4-hydroxybenzyl)-1-(2,4,6-trichlorophen...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6000(3-Ethyl-6-(2-methoxybenzyl)-1-(2,4,6-trichlorophen...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6020(6-(3,4-Dimethoxybenzyl)-3-ethyl-1-(2,4,6-trichloro...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6017(3-Ethyl-6-(3-methoxy-4-methylbenzyl)-1-(2,4,6-tric...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM5984(3-Ethyl-6-isobutyl-1-(2,4,6-trichlorophenyl)-4,5-d...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6001(3-Ethyl-6-(2-hydroxybenzyl)-1-(2,4,6-trichlorophen...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM5968(3-Ethyl-6-methyl-1-(2,4,6-trichlorophenyl)-4,5-dih...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6012(3-Ethyl-6-(4-methoxybenzyl)-1-(2,4,6-trichlorophen...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6006(6-(3-(Ethoxycarbonylmethyl)benzyl)-3-ethyl-1-(2,4,...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6011(6-(4-Aminobenzyl)-3-ethyl-1-(2,4,6-trichlorophenyl...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6026(N-(3-{[3-Ethyl-4-oxo-1-(2,4,6-trichlorophenyl)-4,5...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6028(2-(tert-Butoxycarbonylamino)-N-(4-{[3-ethyl-4-oxo-...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6025(3-Ethyl-6-(3-hydroxybenzyl)-1-(2,4,6-trichlorophen...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6023(3-Ethyl-6-(3-hydroxy-4-methoxybenzyl)-1-(2,4,6-tri...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM6009(3-Ethyl-6-(pyrid-3-ylmethyl)-1-(2,4,6-trichlorophe...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J692NPubMed
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