Compile Data Set for Download or QSAR
Found 204 with Last Name = 'meena' and Initial = 'cl'
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Division of Organic Chemistry CSIR-National Chemical Laboratory (NCL)

Curated by ChEMBL
LigandPNGBDBM50235980(2-((2S,5R,8S,11S)-5-benzyl-11-(3-guanidinopropyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 0.540nMAssay Description:Inhibition of vitronectin binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta3 (Gly27 to Asp718 residues) expressed in CHO c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P16PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Division of Organic Chemistry CSIR-National Chemical Laboratory (NCL)

Curated by ChEMBL
LigandPNGBDBM50004058((2S)-2-(butylsulfonylamino)-3-[4-(4-piperidin-4-yl...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of fibrinogen binding to human platelet integrin alpha2b beta3 by ELISA based solid phase binding assayMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(MOUSE)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50072394(1-[3-(1H-4-imidazolyl)-2-(5-oxotetrahydro-1H-2-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Displacement of [3H]-1-MeHis-TRH from mouse TRH-R1 expressed in HEK293 cells incubated up to 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3NZ9PubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Division of Organic Chemistry CSIR-National Chemical Laboratory (NCL)

Curated by ChEMBL
LigandPNGBDBM50545184(CHEMBL4642869)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Inhibition of vitronectin binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta3 (Gly27 to Asp718 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P16PubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Division of Organic Chemistry CSIR-National Chemical Laboratory (NCL)

Curated by ChEMBL
LigandPNGBDBM50545181(CHEMBL4633117)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:Inhibition of vitronectin binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta3 (Gly27 to Asp718 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P16PubMed
TargetThyrotropin-releasing hormone receptor(Mus musculus)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50072394(1-[3-(1H-4-imidazolyl)-2-(5-oxotetrahydro-1H-2-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Displacement of [3H]-1-MeHis-TRH from mouse TRH-R2 expressed in HEK293 cells incubated up to 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3NZ9PubMed
TargetThyrotropin-releasing hormone receptor(Mus musculus)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50072394(1-[3-(1H-4-imidazolyl)-2-(5-oxotetrahydro-1H-2-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Displacement of [3H]-Me-His-TRH from mouse TRH-R2 expressed in HEK293 cells preincubated for 15 mins measured after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8NKFPubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Division of Organic Chemistry CSIR-National Chemical Laboratory (NCL)

Curated by ChEMBL
LigandPNGBDBM50235980(2-((2S,5R,8S,11S)-5-benzyl-11-(3-guanidinopropyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of vitronectin binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta5 (Gly24 to Asn719 residues) expressed in CHO c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P16PubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Division of Organic Chemistry CSIR-National Chemical Laboratory (NCL)

Curated by ChEMBL
LigandPNGBDBM50545180(CHEMBL4643939)copy SMILEScopy InChI
Affinity DataIC50: 9.90nMAssay Description:Inhibition of vitronectin binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta3 (Gly27 to Asp718 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P16PubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Division of Organic Chemistry CSIR-National Chemical Laboratory (NCL)

Curated by ChEMBL
LigandPNGBDBM50545183(CHEMBL4648191)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of vitronectin binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta3 (Gly27 to Asp718 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P16PubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Division of Organic Chemistry CSIR-National Chemical Laboratory (NCL)

Curated by ChEMBL
LigandPNGBDBM50235980(2-((2S,5R,8S,11S)-5-benzyl-11-(3-guanidinopropyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of fibronectin binding to recombinant human integrin alpha5 (Phe42 to Tyr995 residues) beta1 (Gln21 to Asp728 residues) expressed in CHO c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P16PubMed
TargetThyrotropin-releasing hormone receptor(MOUSE)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50072394(1-[3-(1H-4-imidazolyl)-2-(5-oxotetrahydro-1H-2-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Displacement of [3H]-Me-His-TRH from mouse TRH-R1 expressed in HEK293 cells preincubated for 15 mins measured after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8NKFPubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Division of Organic Chemistry CSIR-National Chemical Laboratory (NCL)

Curated by ChEMBL
LigandPNGBDBM50429461(CHEMBL2332369)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of latency-associated peptide/TGF-beta binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta6 (Gly22 to Asn707 resi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P16PubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Division of Organic Chemistry CSIR-National Chemical Laboratory (NCL)

Curated by ChEMBL
LigandPNGBDBM50545181(CHEMBL4633117)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of vitronectin binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta5 (Gly24 to Asn719 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P16PubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Division of Organic Chemistry CSIR-National Chemical Laboratory (NCL)

Curated by ChEMBL
LigandPNGBDBM50545184(CHEMBL4642869)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of vitronectin binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta5 (Gly24 to Asn719 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P16PubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Division of Organic Chemistry CSIR-National Chemical Laboratory (NCL)

Curated by ChEMBL
LigandPNGBDBM50545183(CHEMBL4648191)copy SMILEScopy InChI
Affinity DataIC50: 66nMAssay Description:Inhibition of vitronectin binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta5 (Gly24 to Asn719 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P16PubMed
TargetThyrotropin-releasing hormone receptor(Mus musculus)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158394(CHEMBL3780645)copy SMILEScopy InChI
Affinity DataIC50: 69nMAssay Description:Displacement of [3H]-Me-His-TRH from mouse TRH-R2 expressed in HEK293 cells preincubated for 15 mins measured after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8NKFPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Division of Organic Chemistry CSIR-National Chemical Laboratory (NCL)

Curated by ChEMBL
LigandPNGBDBM50545182(CHEMBL4636873)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Inhibition of vitronectin binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta3 (Gly27 to Asp718 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P16PubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Division of Organic Chemistry CSIR-National Chemical Laboratory (NCL)

Curated by ChEMBL
LigandPNGBDBM50545184(CHEMBL4642869)copy SMILEScopy InChI
Affinity DataIC50: 88nMAssay Description:Inhibition of fibronectin binding to recombinant human integrin alpha5 (Phe42 to Tyr995 residues) beta1 (Gln21 to Asp728 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P16PubMed
TargetIntegrin alpha-V/beta-8(Homo sapiens (Human))
Division of Organic Chemistry CSIR-National Chemical Laboratory (NCL)

Curated by ChEMBL
LigandPNGBDBM50429461(CHEMBL2332369)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of latency-associated peptide/TGF-beta binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta8 (Glu43 to Arg684 resi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P16PubMed
TargetThyrotropin-releasing hormone receptor(Mus musculus)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158418(CHEMBL3780746)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Displacement of [3H]-Me-His-TRH from mouse TRH-R2 expressed in HEK293 cells preincubated for 15 mins measured after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8NKFPubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Division of Organic Chemistry CSIR-National Chemical Laboratory (NCL)

Curated by ChEMBL
LigandPNGBDBM50545181(CHEMBL4633117)copy SMILEScopy InChI
Affinity DataIC50: 141nMAssay Description:Inhibition of fibronectin binding to recombinant human integrin alpha5 (Phe42 to Tyr995 residues) beta1 (Gln21 to Asp728 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P16PubMed
TargetThyrotropin-releasing hormone receptor(MOUSE)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158418(CHEMBL3780746)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Displacement of [3H]-Me-His-TRH from mouse TRH-R1 expressed in HEK293 cells preincubated for 15 mins measured after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8NKFPubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Division of Organic Chemistry CSIR-National Chemical Laboratory (NCL)

Curated by ChEMBL
LigandPNGBDBM50545183(CHEMBL4648191)copy SMILEScopy InChI
Affinity DataIC50: 178nMAssay Description:Inhibition of latency-associated peptide/TGF-beta binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta6 (Gly22 to Asn707 resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P16PubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Division of Organic Chemistry CSIR-National Chemical Laboratory (NCL)

Curated by ChEMBL
LigandPNGBDBM50545180(CHEMBL4643939)copy SMILEScopy InChI
Affinity DataIC50: 303nMAssay Description:Inhibition of vitronectin binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta5 (Gly24 to Asn719 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P16PubMed
TargetIntegrin alpha-V/beta-8(Homo sapiens (Human))
Division of Organic Chemistry CSIR-National Chemical Laboratory (NCL)

Curated by ChEMBL
LigandPNGBDBM50545183(CHEMBL4648191)copy SMILEScopy InChI
Affinity DataIC50: 319nMAssay Description:Inhibition of latency-associated peptide/TGF-beta binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta8 (Glu43 to Arg684 resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P16PubMed
TargetThyrotropin-releasing hormone receptor(MOUSE)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158394(CHEMBL3780645)copy SMILEScopy InChI
Affinity DataIC50: 324nMAssay Description:Displacement of [3H]-Me-His-TRH from mouse TRH-R1 expressed in HEK293 cells preincubated for 15 mins measured after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8NKFPubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Division of Organic Chemistry CSIR-National Chemical Laboratory (NCL)

Curated by ChEMBL
LigandPNGBDBM50545181(CHEMBL4633117)copy SMILEScopy InChI
Affinity DataIC50: 378nMAssay Description:Inhibition of latency-associated peptide/TGF-beta binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta6 (Gly22 to Asn707 resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P16PubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Division of Organic Chemistry CSIR-National Chemical Laboratory (NCL)

Curated by ChEMBL
LigandPNGBDBM50545184(CHEMBL4642869)copy SMILEScopy InChI
Affinity DataIC50: 608nMAssay Description:Inhibition of latency-associated peptide/TGF-beta binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta6 (Gly22 to Asn707 resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P16PubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Division of Organic Chemistry CSIR-National Chemical Laboratory (NCL)

Curated by ChEMBL
LigandPNGBDBM50545180(CHEMBL4643939)copy SMILEScopy InChI
Affinity DataIC50: 623nMAssay Description:Inhibition of fibronectin binding to recombinant human integrin alpha5 (Phe42 to Tyr995 residues) beta1 (Gln21 to Asp728 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P16PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Division of Organic Chemistry CSIR-National Chemical Laboratory (NCL)

Curated by ChEMBL
LigandPNGBDBM50545180(CHEMBL4643939)copy SMILEScopy InChI
Affinity DataIC50: 657nMAssay Description:Inhibition of fibrinogen binding to human platelet integrin alpha2b beta3 by ELISA based solid phase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P16PubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Division of Organic Chemistry CSIR-National Chemical Laboratory (NCL)

Curated by ChEMBL
LigandPNGBDBM50545182(CHEMBL4636873)copy SMILEScopy InChI
Affinity DataIC50: 709nMAssay Description:Inhibition of latency-associated peptide/TGF-beta binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta6 (Gly22 to Asn707 resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P16PubMed
TargetIntegrin alpha-V/beta-8(Homo sapiens (Human))
Division of Organic Chemistry CSIR-National Chemical Laboratory (NCL)

Curated by ChEMBL
LigandPNGBDBM50545181(CHEMBL4633117)copy SMILEScopy InChI
Affinity DataIC50: 806nMAssay Description:Inhibition of latency-associated peptide/TGF-beta binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta8 (Glu43 to Arg684 resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P16PubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Division of Organic Chemistry CSIR-National Chemical Laboratory (NCL)

Curated by ChEMBL
LigandPNGBDBM50545182(CHEMBL4636873)copy SMILEScopy InChI
Affinity DataIC50: 921nMAssay Description:Inhibition of fibronectin binding to recombinant human integrin alpha5 (Phe42 to Tyr995 residues) beta1 (Gln21 to Asp728 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P16PubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Division of Organic Chemistry CSIR-National Chemical Laboratory (NCL)

Curated by ChEMBL
LigandPNGBDBM50545183(CHEMBL4648191)copy SMILEScopy InChI
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of fibronectin binding to recombinant human integrin alpha5 (Phe42 to Tyr995 residues) beta1 (Gln21 to Asp728 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P16PubMed
TargetThyrotropin-releasing hormone receptor(MOUSE)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158395(CHEMBL3782037)copy SMILEScopy InChI
Affinity DataIC50: 1.18E+3nMAssay Description:Displacement of [3H]-Me-His-TRH from mouse TRH-R1 expressed in HEK293 cells preincubated for 15 mins measured after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8NKFPubMed
TargetIntegrin alpha-V/beta-8(Homo sapiens (Human))
Division of Organic Chemistry CSIR-National Chemical Laboratory (NCL)

Curated by ChEMBL
LigandPNGBDBM50545184(CHEMBL4642869)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of latency-associated peptide/TGF-beta binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta8 (Glu43 to Arg684 resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P16PubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Division of Organic Chemistry CSIR-National Chemical Laboratory (NCL)

Curated by ChEMBL
LigandPNGBDBM50545180(CHEMBL4643939)copy SMILEScopy InChI
Affinity DataIC50: 1.97E+3nMAssay Description:Inhibition of latency-associated peptide/TGF-beta binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta6 (Gly22 to Asn707 resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P16PubMed
TargetThyrotropin-releasing hormone receptor(Mus musculus)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158398(CHEMBL3780633)copy SMILEScopy InChI
Affinity DataIC50: 2.24E+3nMAssay Description:Displacement of [3H]-Me-His-TRH from mouse TRH-R2 expressed in HEK293 cells preincubated for 15 mins measured after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8NKFPubMed
TargetThyrotropin-releasing hormone receptor(Mus musculus)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158395(CHEMBL3782037)copy SMILEScopy InChI
Affinity DataIC50: 2.45E+3nMAssay Description:Displacement of [3H]-Me-His-TRH from mouse TRH-R2 expressed in HEK293 cells preincubated for 15 mins measured after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8NKFPubMed
TargetIntegrin alpha-V/beta-8(Homo sapiens (Human))
Division of Organic Chemistry CSIR-National Chemical Laboratory (NCL)

Curated by ChEMBL
LigandPNGBDBM50545180(CHEMBL4643939)copy SMILEScopy InChI
Affinity DataIC50: 3.95E+3nMAssay Description:Inhibition of latency-associated peptide/TGF-beta binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta8 (Glu43 to Arg684 resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P16PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Division of Organic Chemistry CSIR-National Chemical Laboratory (NCL)

Curated by ChEMBL
LigandPNGBDBM50545182(CHEMBL4636873)copy SMILEScopy InChI
Affinity DataIC50: 4.86E+3nMAssay Description:Inhibition of fibrinogen binding to human platelet integrin alpha2b beta3 by ELISA based solid phase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P16PubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Division of Organic Chemistry CSIR-National Chemical Laboratory (NCL)

Curated by ChEMBL
LigandPNGBDBM50545182(CHEMBL4636873)copy SMILEScopy InChI
Affinity DataIC50: 4.93E+3nMAssay Description:Inhibition of vitronectin binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta5 (Gly24 to Asn719 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P16PubMed
TargetIntegrin alpha-V/beta-8(Homo sapiens (Human))
Division of Organic Chemistry CSIR-National Chemical Laboratory (NCL)

Curated by ChEMBL
LigandPNGBDBM50545182(CHEMBL4636873)copy SMILEScopy InChI
Affinity DataIC50: 6.88E+3nMAssay Description:Inhibition of latency-associated peptide/TGF-beta binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta8 (Glu43 to Arg684 resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P16PubMed
TargetThyrotropin-releasing hormone receptor(Mus musculus)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158409(CHEMBL3779931)copy SMILEScopy InChI
Affinity DataIC50: 7.60E+3nMAssay Description:Displacement of [3H]-Me-His-TRH from mouse TRH-R2 expressed in HEK293 cells preincubated for 15 mins measured after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8NKFPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Division of Organic Chemistry CSIR-National Chemical Laboratory (NCL)

Curated by ChEMBL
LigandPNGBDBM50545181(CHEMBL4633117)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of fibrinogen binding to human platelet integrin alpha2b beta3 by ELISA based solid phase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P16PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Division of Organic Chemistry CSIR-National Chemical Laboratory (NCL)

Curated by ChEMBL
LigandPNGBDBM50545184(CHEMBL4642869)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of fibrinogen binding to human platelet integrin alpha2b beta3 by ELISA based solid phase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P16PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Division of Organic Chemistry CSIR-National Chemical Laboratory (NCL)

Curated by ChEMBL
LigandPNGBDBM50545183(CHEMBL4648191)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of fibrinogen binding to human platelet integrin alpha2b beta3 by ELISA based solid phase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P16PubMed
TargetThyrotropin-releasing hormone receptor(Mus musculus)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158531(CHEMBL3780248)copy SMILEScopy InChI
Affinity DataIC50: 1.36E+4nMAssay Description:Displacement of [3H]-Me-His-TRH from mouse TRH-R2 expressed in HEK293 cells preincubated for 15 mins measured after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8NKFPubMed
TargetThyrotropin-releasing hormone receptor(Mus musculus)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158399(CHEMBL3780802)copy SMILEScopy InChI
Affinity DataIC50: 1.56E+4nMAssay Description:Displacement of [3H]-Me-His-TRH from mouse TRH-R2 expressed in HEK293 cells preincubated for 15 mins measured after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8NKFPubMed
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