Compile Data Set for Download or QSAR
Found 47 with Last Name = 'ireland' and Initial = 'cm'
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
University of Utah

Curated by ChEMBL
LigandPNGBDBM50059889((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of MEK1 phosphorylation by activated human recombinant RafMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FQ9XCDPubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
University of Utah

Curated by ChEMBL
LigandPNGBDBM50059889((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of Mitogen-activated protein kinase (MAPK)phosphorylation by activated MEK-1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FQ9XCDPubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
University of Utah

Curated by ChEMBL
LigandPNGBDBM50108776(4-(2-Amino-5-oxo-3,5-dihydro-imidazol-4-ylidene)-2...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of Mitogen-activated protein kinase (MAPK)phosphorylation by activated MEK-1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FQ9XCDPubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
University of Utah

Curated by ChEMBL
LigandPNGBDBM7491((4Z)-4-(2-amino-5-oxo-3,5-dihydro-4H-imidazol-4-yl...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of Mitogen-activated protein kinase (MAPK)phosphorylation by activated MEK-1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FQ9XCDPubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
University of Utah

Curated by ChEMBL
LigandPNGBDBM50252375(CHEMBL446072 | Spheciosterol sulfate C)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of PKCzeta (unknown origin) by TR-FRET based lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7G17PubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
University of Utah

Curated by ChEMBL
LigandPNGBDBM50252374(CHEMBL475118 | Spheciosterol sulfate B)copy SMILEScopy InChI
Affinity DataIC50: 530nMAssay Description:Inhibition of PKCzeta (unknown origin) by TR-FRET based lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7G17PubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
University of Utah

Curated by ChEMBL
LigandPNGBDBM50108774(2-Bromo-6,7-dihydro-1H,5H-pyrrolo[2,3-c]azepine-4,...)copy SMILEScopy InChI
Affinity DataIC50: 539nMAssay Description:Inhibition of Mitogen-activated protein kinase (MAPK)phosphorylation by activated MEK-1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FQ9XCDPubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
University of Utah

Curated by ChEMBL
LigandPNGBDBM50363645(DEBROMOHYMENIALDISINE)copy SMILEScopy InChI
Affinity DataIC50: 824nMAssay Description:Inhibition of Mitogen-activated protein kinase (MAPK)phosphorylation by activated MEK-1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FQ9XCDPubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
University of Utah

Curated by ChEMBL
LigandPNGBDBM50252376(CHEMBL455091 | Topsentiasterol sulfate E)copy SMILEScopy InChI
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of PKCzeta (unknown origin) by TR-FRET based lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7G17PubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
University of Utah

Curated by ChEMBL
LigandPNGBDBM59117(CHEMBL151430 | Hymenialdisine, 11b)copy SMILEScopy InChI
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of Mitogen-activated protein kinase (MAPK)phosphorylation by activated MEK-1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FQ9XCDPubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
University of Utah

Curated by ChEMBL
LigandPNGBDBM50252373(CHEMBL447723 | Spheciosterol sulfate A)copy SMILEScopy InChI
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of PKCzeta (unknown origin) by TR-FRET based lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7G17PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
University of Utah

Curated by ChEMBL
LigandPNGBDBM50108776(4-(2-Amino-5-oxo-3,5-dihydro-imidazol-4-ylidene)-2...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of MEK1 phosphorylation by activated human recombinant RafMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FQ9XCDPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
University of Utah

Curated by ChEMBL
LigandPNGBDBM59117(CHEMBL151430 | Hymenialdisine, 11b)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of MEK1 phosphorylation by activated human recombinant RafMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FQ9XCDPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
University of Utah

Curated by ChEMBL
LigandPNGBDBM50108777(6,7-Dihydro-1H,5H-pyrrolo[2,3-c]azepine-4,8-dione ...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of MEK1 phosphorylation by activated human recombinant RafMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FQ9XCDPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
University of Utah

Curated by ChEMBL
LigandPNGBDBM7491((4Z)-4-(2-amino-5-oxo-3,5-dihydro-4H-imidazol-4-yl...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of MEK1 phosphorylation by activated human recombinant RafMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FQ9XCDPubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
University of Utah

Curated by ChEMBL
LigandPNGBDBM50108777(6,7-Dihydro-1H,5H-pyrrolo[2,3-c]azepine-4,8-dione ...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Mitogen-activated protein kinase (MAPK)phosphorylation by activated MEK-1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FQ9XCDPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
University of Utah

Curated by ChEMBL
LigandPNGBDBM50108773(4,5-Dibromo-1H-pyrrole-2-carboxylic acid amide | 4...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of MEK1 phosphorylation by activated human recombinant RafMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FQ9XCDPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
University of Utah

Curated by ChEMBL
LigandPNGBDBM50363645(DEBROMOHYMENIALDISINE)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of MEK1 phosphorylation by activated human recombinant RafMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FQ9XCDPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
University of Utah

Curated by ChEMBL
LigandPNGBDBM50108774(2-Bromo-6,7-dihydro-1H,5H-pyrrolo[2,3-c]azepine-4,...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of MEK1 phosphorylation by activated human recombinant RafMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FQ9XCDPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
University of Utah

Curated by ChEMBL
LigandPNGBDBM50220547(4,5-Dibromo-1H-pyrrole-2-carboxylic acid [3-(2-ami...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of MEK1 phosphorylation by activated human recombinant RafMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FQ9XCDPubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
University of Utah

Curated by ChEMBL
LigandPNGBDBM50220547(4,5-Dibromo-1H-pyrrole-2-carboxylic acid [3-(2-ami...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Mitogen-activated protein kinase (MAPK)phosphorylation by activated MEK-1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FQ9XCDPubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
University of Utah

Curated by ChEMBL
LigandPNGBDBM50108773(4,5-Dibromo-1H-pyrrole-2-carboxylic acid amide | 4...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Mitogen-activated protein kinase (MAPK)phosphorylation by activated MEK-1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FQ9XCDPubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
University of Utah

Curated by ChEMBL
LigandPNGBDBM50108771(2'-amino-3'-methoxyflavone | 2-(2-Amino-3-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of Mitogen-activated protein kinase (MAPK)phosphorylation by activated MEK-1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FQ9XCDPubMed
TargetInsulin receptor(Mus musculus)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50066982(5-[1,4-Bis-(4-methoxy-benzyl)-1H-imidazol-2-ylamin...)copy SMILEScopy InChI
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of insulin receptor mediated mitogenesis of NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7FDRPubMed
TargetInsulin receptor(Mus musculus)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50066983(5-[1-(4-Hydroxy-benzyl)-4-(4-methoxy-benzyl)-1H-im...)copy SMILEScopy InChI
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of insulin receptor mediated mitogenesis of NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7FDRPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
University of Utah

Curated by ChEMBL
LigandPNGBDBM50108771(2'-amino-3'-methoxyflavone | 2-(2-Amino-3-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MEK1 phosphorylation by activated human recombinant RafMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FQ9XCDPubMed
TargetEpidermal growth factor receptor(Mus musculus)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50066984(4-(5-(4-hydroxybenzyl)-4-(4-methoxybenzyl)-1-methy...)copy SMILEScopy InChI
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of Epidermal growth factor receptor mediated mitogenesis of NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7FDRPubMed
TargetEpidermal growth factor receptor(Mus musculus)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50066983(5-[1-(4-Hydroxy-benzyl)-4-(4-methoxy-benzyl)-1H-im...)copy SMILEScopy InChI
Affinity DataIC50: 2.27E+4nMAssay Description:Inhibition of Epidermal growth factor receptor mediated mitogenesis of NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7FDRPubMed
TargetEpidermal growth factor receptor(Mus musculus)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50066982(5-[1,4-Bis-(4-methoxy-benzyl)-1H-imidazol-2-ylamin...)copy SMILEScopy InChI
Affinity DataIC50: 3.69E+4nMAssay Description:Inhibition of Epidermal growth factor receptor mediated mitogenesis of NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7FDRPubMed
TargetIntegrase(Human immunodeficiency virus 1)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50485630(Mollamide F)copy SMILEScopy InChI
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of HIV-1 integrase by colorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5RQZPubMed
TargetCystathionine beta-synthase(Homo sapiens (Human))
University of Utah

Curated by ChEMBL
LigandPNGBDBM50064289(CHEMBL3403661)copy SMILEScopy InChI
Affinity DataIC50: 8.30E+4nMAssay Description:Inhibition of full-length wild-type cystathionine beta-synthase (unknown origin) assessed as inhibition of H2S production by fluorescence assay in pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JT9PubMed
TargetCystathionine beta-synthase(Homo sapiens (Human))
University of Utah

Curated by ChEMBL
LigandPNGBDBM50064264(CHEMBL3403662)copy SMILEScopy InChI
Affinity DataIC50: 8.70E+4nMAssay Description:Inhibition of full-length wild-type cystathionine beta-synthase (unknown origin) assessed as inhibition of H2S production by fluorescence assay in pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JT9PubMed
TargetCystathionine beta-synthase(Homo sapiens (Human))
University of Utah

Curated by ChEMBL
LigandPNGBDBM50064292(Rubrolide A)copy SMILEScopy InChI
Affinity DataIC50: 1.08E+5nMAssay Description:Inhibition of full-length wild-type cystathionine beta-synthase (unknown origin) assessed as inhibition of H2S production by fluorescence assay in pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JT9PubMed
TargetCystathionine beta-synthase(Homo sapiens (Human))
University of Utah

Curated by ChEMBL
LigandPNGBDBM50064290(CHEMBL1956805)copy SMILEScopy InChI
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of full-length wild-type cystathionine beta-synthase (unknown origin) assessed as inhibition of H2S production by fluorescence assay in pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JT9PubMed
TargetCystathionine beta-synthase(Homo sapiens (Human))
University of Utah

Curated by ChEMBL
LigandPNGBDBM50064263(CHEMBL3403663)copy SMILEScopy InChI
Affinity DataIC50: 1.36E+5nMAssay Description:Inhibition of full-length wild-type cystathionine beta-synthase (unknown origin) assessed as inhibition of H2S production by fluorescence assay in pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JT9PubMed
TargetCystathionine beta-synthase(Homo sapiens (Human))
University of Utah

Curated by ChEMBL
LigandPNGBDBM50108773(4,5-Dibromo-1H-pyrrole-2-carboxylic acid amide | 4...)copy SMILEScopy InChI
Affinity DataIC50: 1.56E+5nMAssay Description:Inhibition of full-length wild-type cystathionine beta-synthase (unknown origin) assessed as inhibition of H2S production by fluorescence assay in pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JT9PubMed
TargetCystathionine beta-synthase(Homo sapiens (Human))
University of Utah

Curated by ChEMBL
LigandPNGBDBM50064265(CHEMBL1956777)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+5nMAssay Description:Inhibition of full-length wild-type cystathionine beta-synthase (unknown origin) assessed as inhibition of H2S production by fluorescence assay in pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JT9PubMed
TargetCystathionine beta-synthase(Homo sapiens (Human))
University of Utah

Curated by ChEMBL
LigandPNGBDBM50064291(CHEMBL1957775)copy SMILEScopy InChI
Affinity DataIC50: 1.87E+5nMAssay Description:Inhibition of full-length wild-type cystathionine beta-synthase (unknown origin) assessed as inhibition of H2S production by fluorescence assay in pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JT9PubMed
TargetInsulin receptor(Mus musculus)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50066984(4-(5-(4-hydroxybenzyl)-4-(4-methoxybenzyl)-1-methy...)copy SMILEScopy InChI
Affinity DataIC50: 2.42E+5nMAssay Description:Inhibition of insulin receptor mediated mitogenesis of NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7FDRPubMed
TargetIntegrase(Human immunodeficiency virus 1)
University of Utah

Curated by ChEMBL
LigandPNGBDBM26985(2-triaza-1,2-diyne | CHEMBL79455 | CHEMBL89295 | N...)copy SMILEScopy InChI
Affinity DataIC50: 4.60E+7nMAssay Description:Inhibition of HIV-1 integrase by colorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5RQZPubMed
TargetTranscription factor p65(Homo sapiens (Human))
University of Utah

Curated by ChEMBL
LigandPNGBDBM50252376(CHEMBL455091 | Topsentiasterol sulfate E)copy SMILEScopy InChI
Affinity DataEC50:  1.20E+4nMAssay Description:Inhibition of IL1-induced NFkappaB P65 activation in human osteoarthritic primary chondrocytes preincubated 2 hrs before addition of IL1 by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7G17PubMed
TargetTranscription factor p65(Homo sapiens (Human))
University of Utah

Curated by ChEMBL
LigandPNGBDBM50252375(CHEMBL446072 | Spheciosterol sulfate C)copy SMILEScopy InChI
Affinity DataEC50:  1.20E+4nMAssay Description:Inhibition of IL1-induced NFkappaB P65 activation in human osteoarthritic primary chondrocytes preincubated 2 hrs before addition of IL1 by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7G17PubMed
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
University of Utah

Curated by ChEMBL
LigandPNGBDBM50478130(CHEMBL271159)copy SMILEScopy InChI
Affinity DataEC50:  6.00E+3nMAssay Description:Inhibition of hypoxia-induced HIF1 transcriptional activation in human U251-HRE cells by luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95CZSPubMed
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
University of Utah

Curated by ChEMBL
LigandPNGBDBM50478131(CHEMBL270091)copy SMILEScopy InChI
Affinity DataEC50:  8.00E+3nMAssay Description:Inhibition of hypoxia-induced HIF1 transcriptional activation in human U251-HRE cells by luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95CZSPubMed
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
University of Utah

Curated by ChEMBL
LigandPNGBDBM50478132(CHEMBL259472)copy SMILEScopy InChI
Affinity DataEC50:  1.30E+4nMAssay Description:Inhibition of hypoxia-induced HIF1 transcriptional activation in human U251-HRE cells by luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95CZSPubMed
TargetTranscription factor p65(Homo sapiens (Human))
University of Utah

Curated by ChEMBL
LigandPNGBDBM50252374(CHEMBL475118 | Spheciosterol sulfate B)copy SMILEScopy InChI
Affinity DataEC50:  1.20E+4nMAssay Description:Inhibition of IL1-induced NFkappaB P65 activation in human osteoarthritic primary chondrocytes preincubated 2 hrs before addition of IL1 by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7G17PubMed
TargetTranscription factor p65(Homo sapiens (Human))
University of Utah

Curated by ChEMBL
LigandPNGBDBM50252373(CHEMBL447723 | Spheciosterol sulfate A)copy SMILEScopy InChI
Affinity DataEC50:  1.20E+4nMAssay Description:Inhibition of IL1-induced NFkappaB P65 activation in human osteoarthritic primary chondrocytes preincubated 2 hrs before addition of IL1 by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7G17PubMed