Compile Data Set for Download or QSAR
Found 45 with Last Name = 'anthony rawlings' and Initial = 'd'
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50259548(6-(5'-chloro-2'-isobutoxy-biphenyl-2-yl)-pyridine-...)copy SMILEScopy InChI
Affinity DataKi:  2.51nMAssay Description:Displacement of [3H]PGE2 from EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50183182(2''-benzyloxy-5''-chloro-[1,1';2',1'']terphenyl-3-...)copy SMILEScopy InChI
Affinity DataKi:  31.6nMAssay Description:Antagonist activity at EP1 receptor assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50259548(6-(5'-chloro-2'-isobutoxy-biphenyl-2-yl)-pyridine-...)copy SMILEScopy InChI
Affinity DataKi:  316nMAssay Description:Binding affinity to TP receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50259548(6-(5'-chloro-2'-isobutoxy-biphenyl-2-yl)-pyridine-...)copy SMILEScopy InChI
Affinity DataKi:  2.00E+3nMAssay Description:Activity at EP3 receptor by FLIPR methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50413672(CHEMBL516324)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50413667(CHEMBL514574)copy SMILEScopy InChI
Affinity DataIC50: 3.98nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50413670(CHEMBL458452)copy SMILEScopy InChI
Affinity DataIC50: 3.98nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50413668(CHEMBL457142)copy SMILEScopy InChI
Affinity DataIC50: 5.01nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50413673(CHEMBL456496)copy SMILEScopy InChI
Affinity DataIC50: 6.31nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50413669(CHEMBL515981)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50413674(CHEMBL456495)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50413671(CHEMBL458448)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50413663(CHEMBL466549)copy SMILEScopy InChI
Affinity DataIC50: 12.6nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50259548(6-(5'-chloro-2'-isobutoxy-biphenyl-2-yl)-pyridine-...)copy SMILEScopy InChI
Affinity DataIC50: 12.6nMAssay Description:Binding affinity to rat EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50259548(6-(5'-chloro-2'-isobutoxy-biphenyl-2-yl)-pyridine-...)copy SMILEScopy InChI
Affinity DataIC50: 15.8nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50259548(6-(5'-chloro-2'-isobutoxy-biphenyl-2-yl)-pyridine-...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Binding affinity to human EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50413664(CHEMBL467579)copy SMILEScopy InChI
Affinity DataIC50: 19.9nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50413685(CHEMBL516787)copy SMILEScopy InChI
Affinity DataIC50: 19.9nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50413679(CHEMBL456707)copy SMILEScopy InChI
Affinity DataIC50: 19.9nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50413662(CHEMBL459537)copy SMILEScopy InChI
Affinity DataIC50: 39.8nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50183182(2''-benzyloxy-5''-chloro-[1,1';2',1'']terphenyl-3-...)copy SMILEScopy InChI
Affinity DataIC50: 50.1nMAssay Description:Displacement of [3H]PGE2 from EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50183182(2''-benzyloxy-5''-chloro-[1,1';2',1'']terphenyl-3-...)copy SMILEScopy InChI
Affinity DataIC50: 50.1nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50413665(CHEMBL467578)copy SMILEScopy InChI
Affinity DataIC50: 50.1nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50413675(CHEMBL514425)copy SMILEScopy InChI
Affinity DataIC50: 63.1nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50413666(CHEMBL512617)copy SMILEScopy InChI
Affinity DataIC50: 63.1nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50413676(CHEMBL459091)copy SMILEScopy InChI
Affinity DataIC50: 79.4nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50413681(CHEMBL458008)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50413659(CHEMBL499155)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50413686(CHEMBL457797)copy SMILEScopy InChI
Affinity DataIC50: 126nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50413661(CHEMBL458858)copy SMILEScopy InChI
Affinity DataIC50: 158nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50413660(CHEMBL456679)copy SMILEScopy InChI
Affinity DataIC50: 251nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50413684(CHEMBL460168)copy SMILEScopy InChI
Affinity DataIC50: 316nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50413677(CHEMBL515697)copy SMILEScopy InChI
Affinity DataIC50: 501nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50413678(CHEMBL456919)copy SMILEScopy InChI
Affinity DataIC50: 794nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50413680(CHEMBL456706)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50413682(CHEMBL462294)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50413683(CHEMBL460169)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50259548(6-(5'-chloro-2'-isobutoxy-biphenyl-2-yl)-pyridine-...)copy SMILEScopy InChI
Affinity DataIC50: 1.58E+3nMAssay Description:Activity at TP receptor by FLIPR methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetProstaglandin F2-alpha receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50259548(6-(5'-chloro-2'-isobutoxy-biphenyl-2-yl)-pyridine-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Activity at PGF2alpha receptor by FLIPR methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50197898(6-(2-(2-(2,4-difluorobenzyloxy)-5-chlorophenyl)cyc...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50259548(6-(5'-chloro-2'-isobutoxy-biphenyl-2-yl)-pyridine-...)copy SMILEScopy InChI
Affinity DataIC50: 3.16E+4nMAssay Description:Displacement of [3H]dofetilide from human ERG receptor by FLIPR methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50197898(6-(2-(2-(2,4-difluorobenzyloxy)-5-chlorophenyl)cyc...)copy SMILEScopy InChI
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50197898(6-(2-(2-(2,4-difluorobenzyloxy)-5-chlorophenyl)cyc...)copy SMILEScopy InChI
Affinity DataIC50: 8.90E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50197898(6-(2-(2-(2,4-difluorobenzyloxy)-5-chlorophenyl)cyc...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50197898(6-(2-(2-(2,4-difluorobenzyloxy)-5-chlorophenyl)cyc...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed