Compile Data Set for Download or QSAR
Found 481 with Last Name = 'armstrong' and Initial = 'd'
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM144315(Gilteritinib | US11512074, Example T-9 | US8969336...)copy SMILEScopy InChI
Affinity DataIC50: 0.290nMAssay Description:Blocking activity against Beta-2 adrenergic receptor in guinea pig tracheal stripsMore data for this Ligand-Target Pair
In DepthDetails
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))TBA
LigandPNGBDBM144315(Gilteritinib | US11512074, Example T-9 | US8969336...)copy SMILEScopy InChI
Affinity DataIC50: 0.730nMAssay Description:Binding affinity towards rat beta adrenergic receptor from heart membranes.More data for this Ligand-Target Pair
In DepthDetails
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))TBA
LigandPNGBDBM50308060(16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,1...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Blocking activity against Beta-2 adrenergic receptor in guinea pig tracheal stripsMore data for this Ligand-Target Pair
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM36423(4-Methyl-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imi...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMT: 2°CAssay Description:Phopholipase D1(PLD)enzymatic inhibition assay using PLD1.d311More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50KBKPubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM50257542((S)-N-(1-(4-(6-fluoro-2-oxo-2,3-dihydro-1H-benzo[d...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human PLD1 in Calu1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4C5WPubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM50423651(CHEMBL2304616)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human PLD1 in Calu1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4C5WPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM50308060(16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,1...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Binding affinity towards rat beta adrenergic receptor from lung membranes.More data for this Ligand-Target Pair
In DepthDetails
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM50258131(CHEMBL492561 | N-(2-(4-(5-bromo-2-oxo-2,3-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human PLD1 in Calu1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4C5WPubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM50257530((S)-N-(1-(4-(5-chloro-2-oxo-2,3-dihydro-1H-benzo[d...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human PLD1 in Calu1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4C5WPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM50308060(16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,1...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Blocking activity against Beta-1 adrenergic receptor in spontaneously beating guinea pig atrial preparationsMore data for this Ligand-Target Pair
In DepthDetails
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM50257531((S)-N-(1-(4-(5-bromo-2-oxo-2,3-dihydro-1H-benzo[d]...)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human PLD1 in Calu1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4C5WPubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM50257541((1R,2R)-N-([S]-1-{4-[5-bromo-2-oxo-2,3-dihydro-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human PLD1 in Calu1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4C5WPubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM50258128(CHEMBL493010 | N-(2-(4-(5-fluoro-2-oxo-2,3-dihydro...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human PLD1 in Calu1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4C5WPubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM50258179(CHEMBL521990 | N-(2-(4-(5-bromo-2-oxo-2,3-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human PLD1 in Calu1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4C5WPubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM50257540((S)-N-(1-(4-(5-bromo-2-oxo-2,3-dihydro-1H-benzo[d]...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human PLD1 in Calu1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4C5WPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50397360(CHEMBL2170177 | US10188756, Compound CN110)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of N-terminal His-tagged full length human HDAC8 expressed in baculovirus expression system using FAM-RHKK(TF-Ac)-NH2 substrate incubated ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC1470PubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM50258181(3,4-difluoro-N-(2-(4-(6-fluoro-2-oxo-2,3-dihydro-1...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human PLD1 in Calu1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4C5WPubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM50257581((S)-N-(1-(4-(5-bromo-2-oxo-2,3-dihydro-1H-benzo[d]...)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:Inhibition of human PLD1 in Calu1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4C5WPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))TBA
LigandPNGBDBM50210177(ONX-0803 | Pacritinib | SB-1518 | SB1518)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Binding affinity towards rat beta adrenergic receptor from lung membranes.More data for this Ligand-Target Pair
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM50257528((S)-4-chloro-N-(1-(4-(5-chloro-2-oxo-2,3-dihydro-1...)copy SMILEScopy InChI
Affinity DataIC50: 6.40nMAssay Description:Inhibition of human PLD1 in Calu1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4C5WPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM50210177(ONX-0803 | Pacritinib | SB-1518 | SB1518)copy SMILEScopy InChI
Affinity DataIC50: 6.40nMAssay Description:Binding affinity towards rat beta adrenergic receptor from lung membranes.More data for this Ligand-Target Pair
In DepthDetails
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM50258180(4-chloro-N-(2-(4-(6-fluoro-2-oxo-2,3-dihydro-1H-be...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of human PLD1 in Calu1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4C5WPubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM50258263((S)-4-chloro-N-(1-(4-(5-fluoro-2-oxo-2,3-dihydro-1...)copy SMILEScopy InChI
Affinity DataIC50: 7.40nMAssay Description:Inhibition of human PLD1 in Calu1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4C5WPubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM50206153(CHEMBL246032 | N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of human PLD1 in Calu1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4C5WPubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM50257529(CHEMBL521677 | racemic trans-N-((S)-1-(4-(5-chloro...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of human PLD1 in Calu1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4C5WPubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM123744(5-Fluoro-N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo[d]imi...)copy SMILEScopy InChI
Affinity DataIC50: 9.5nMT: 2°CAssay Description:PLD in vitro enzymatic assay using phospholipase D1(PLD1).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50KBKPubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM50258083(CHEMBL494183 | N-(2-(4-(5-chloro-2-oxo-2,3-dihydro...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human PLD1 in Calu1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4C5WPubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM50258264((S)-N-(1-(4-(5-chloro-2-oxo-2,3-dihydro-1H-benzo[d...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human PLD1 in Calu1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4C5WPubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM50258262((S)-4-fluoro-N-(1-(4-(5-fluoro-2-oxo-2,3-dihydro-1...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human PLD1 in Calu1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4C5WPubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM50206160(CHEMBL245621 | Halopemide | Halopemide, 8 | N-(2-(...)copy SMILEScopy InChI
Affinity DataIC50: 11nMT: 2°CAssay Description:Phopholipase D1(PLD)enzymatic inhibition assay using PLD1.d311More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50KBKPubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM50257591(CHEMBL493736 | racemic trans-N-((S)-1-(4-(6-fluoro...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of human PLD1 in Calu1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4C5WPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM50210177(ONX-0803 | Pacritinib | SB-1518 | SB1518)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Binding affinity towards rat beta adrenergic receptor from lung membranes.More data for this Ligand-Target Pair
In DepthDetails
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM50258130(4-fluoro-N-(2-(4-(5-fluoro-2-oxo-2,3-dihydro-1H-be...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of human PLD1 in Calu1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4C5WPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50542233(CHEMBL4642398)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Binding affinity to human HDAC8 pre-incubated for 10 mins before FITC-M344 addition and measured after 10 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC1470PubMed
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50258181(3,4-difluoro-N-(2-(4-(6-fluoro-2-oxo-2,3-dihydro-1...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of GFP-labelled human PLD2 HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4C5WPubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM123744(5-Fluoro-N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo[d]imi...)copy SMILEScopy InChI
Affinity DataIC50: 17nMT: 2°CAssay Description:PLD in vitro enzymatic assay using phospholipase D2(PLD2).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50KBKPubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM50258129(4-chloro-N-(2-(4-(5-fluoro-2-oxo-2,3-dihydro-1H-be...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of human PLD1 in Calu1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4C5WPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM50210177(ONX-0803 | Pacritinib | SB-1518 | SB1518)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Binding affinity towards rat beta adrenergic receptor from heart membranes.More data for this Ligand-Target Pair
In DepthDetails
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))TBA
LigandPNGBDBM50210177(ONX-0803 | Pacritinib | SB-1518 | SB1518)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Binding affinity towards rat beta adrenergic receptor from heart membranes.More data for this Ligand-Target Pair
In DepthDetails
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM50206160(CHEMBL245621 | Halopemide | Halopemide, 8 | N-(2-(...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of human PLD1 in Calu1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4C5WPubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM87245(CHEMBL492797 | ML272 | N-(2-(4-(2-Oxo-2,3-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of human PLD1 in Calu1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4C5WPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50542229(CHEMBL4642821)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of N-terminal His-tagged full length human HDAC8 expressed in baculovirus expression system using FAM-RHKK(TF-Ac)-NH2 substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC1470PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM6760((+)-K-252a | CHEMBL281948 | K-252a | methyl (15S,1...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Blocking activity against Beta-2 adrenergic receptor in guinea pig tracheal stripsMore data for this Ligand-Target Pair
In DepthDetails
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM50278141((S)-N-(1-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]dec...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of PLD1 in human Calu1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76CG5PubMed
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM87188(CHEMBL471257 | N-[2-(4-keto-1-phenyl-1,3,8-triazas...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of GFP-labeled PLD2 in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76CG5PubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM123744(5-Fluoro-N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo[d]imi...)copy SMILEScopy InChI
Affinity DataIC50: 33nMT: 2°CAssay Description:Phopholipase D1(PLD)enzymatic inhibition assay using PLD1.d311More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50KBKPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50542224(CHEMBL4637226)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Binding affinity to human HDAC8 pre-incubated for 10 mins before FITC-M344 addition and measured after 10 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC1470PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50542210(CHEMBL4638377)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of N-terminal His-tagged full length human HDAC8 expressed in baculovirus expression system using FAM-RHKK(TF-Ac)-NH2 substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC1470PubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM50257986((1R,2R)-N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo[d]imid...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of human PLD1 in Calu1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4C5WPubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM50258221((S)-3,4-difluoro-N-(1-(4-(4-fluoro-2-oxo-2,3-dihyd...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of human PLD1 in Calu1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4C5WPubMed
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