Compile Data Set for Download or QSAR
Found 150 with Last Name = 'bates' and Initial = 'd'
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448544(N-(2-(4-(furan-2-ylmethyl)piperazin-1-yl)-5- (trif...)copy SMILEScopy InChI
Affinity DataIC50: 0.370nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448683(N-(2-(4-(thiazol-5-ylmethyl)piperazin-1-yl)-5- (tr...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448727(5-(tetrahydro-2H-pyran-4-yl)-N-(2-(4-(thiazol-5- y...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448695(N-(2-(4-(furan-3-ylmethyl)piperazin-1-yl)-5- (trif...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448663(N-(2-(4-(oxazol-5-ylmethyl)piperazin-1-yl)-5- (tri...)copy SMILEScopy InChI
Affinity DataIC50: 0.760nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448673(N-(5-chloro-2-(4-(furan-2-ylmethyl)piperazin-1-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448662(N-(2-(4-(oxazol-4-ylmethyl)piperazin-1-yl)-5- (tri...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448675(N-(2-(4-(furan-2-ylmethyl)piperazin-1-yl)-5- (trif...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448664(5-(tetrahydro-2H-pyran-4-yl)-N-(2-(4-(thiazol-4- y...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448726(N-(2-(4-(isoxazol-5-ylmethyl)piperazin-1-yl)-5-(tr...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448697(N-(2-(4-(furan-3-ylmethyl)piperazin-1-yl)-5- (trif...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM101734(US9695160, 31 | US9796707, Compound 31)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMT: 2°CAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639MW1US Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM101734(US9695160, 31 | US9796707, Compound 31)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125VTMUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM101825(US9695160, 39 | US9796707, Compound 39)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125VTMUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM101825(US9695160, 39 | US9796707, Compound 39)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMT: 2°CAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639MW1US Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448715(N-(2-(4-(isoxazol-5-ylmethyl)piperazin-1-yl)-5-(tr...)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM221074(SPHINX31 | US9695160, 12 | US9796707, Compound 12)copy SMILEScopy InChI
Affinity DataIC50: 3.18nMT: 2°CAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM221074(SPHINX31 | US9695160, 12 | US9796707, Compound 12)copy SMILEScopy InChI
Affinity DataIC50: 3.18nMAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448647(N-(2-(4-((1H-pyrazol-3-yl)methyl)piperazin-1-yl)-5...)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448696(N-(2-(4-((5-methylfuran-2-yl)methyl)piperazin-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 3.70nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM101676(US9695160, 20 | US9796707, Compound 20)copy SMILEScopy InChI
Affinity DataIC50: 4.40nMT: 2°CAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639MW1US Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM101676(US9695160, 20 | US9796707, Compound 20)copy SMILEScopy InChI
Affinity DataIC50: 4.40nMAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125VTMUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM101690(US9695160, 21 | US9796707, Compound 21)copy SMILEScopy InChI
Affinity DataIC50: 4.60nMAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125VTMUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM101690(US9695160, 21 | US9796707, Compound 21)copy SMILEScopy InChI
Affinity DataIC50: 4.60nMT: 2°CAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639MW1US Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448661(N-(2-(4-(oxazol-2-ylmethyl)piperazin-1-yl)-5- (tri...)copy SMILEScopy InChI
Affinity DataIC50: 4.60nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM101824(US9695160, 38 | US9796707, Compound 38)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125VTMUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM101824(US9695160, 38 | US9796707, Compound 38)copy SMILEScopy InChI
Affinity DataIC50: 5nMT: 2°CAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639MW1US Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448729(N-(2-(4-(furan-3-ylmethyl)piperazin-1-yl)-5- (trif...)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448717(N-(2-(4-(isoxazol-5-ylmethyl)piperazin-1-yl)-5-(tr...)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM221074(SPHINX31 | US9695160, 12 | US9796707, Compound 12)copy SMILEScopy InChI
Affinity DataIC50: 5.90nMpH: 7.5 T: 2°CAssay Description:A reaction buffer containing 200 mM Tris pH 7.5, 100 mM MgCl2 and 0.1 mg/ml BSA was added to 43 μM SRSF1Arg-Ser (RS) peptide (NH2-RSPSYGRSRSRSRS...More data for this Ligand-Target Pair
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM221074(SPHINX31 | US9695160, 12 | US9796707, Compound 12)copy SMILEScopy InChI
Affinity DataIC50: 6nMpH: 7.5 T: 2°CAssay Description:A reaction buffer containing 200 mM Tris pH 7.5, 100 mM MgCl2 and 0.1 mg/ml BSA was added to 43 μM SRSF1Arg-Ser (RS) peptide (NH2-RSPSYGRSRSRSRS...More data for this Ligand-Target Pair
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448682(N-(2-(4-(thiazol-4-ylmethyl)piperazin-1-yl)-5- (tr...)copy SMILEScopy InChI
Affinity DataIC50: 6.70nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM101654(US9695160, 14 | US9796707, Compound 14)copy SMILEScopy InChI
Affinity DataIC50: 7.18nMAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125VTMUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM101654(US9695160, 14 | US9796707, Compound 14)copy SMILEScopy InChI
Affinity DataIC50: 7.18nMT: 2°CAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639MW1US Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448674(N-(5-chloro-2-(4-(oxazol-4-ylmethyl)piperazin-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 8.20nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448723(N-(2-(4-(isoxazol-4-ylmethyl)piperazin-1-yl)-5-(tr...)copy SMILEScopy InChI
Affinity DataIC50: 8.80nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448718(US10696661, Compound 65)copy SMILEScopy InChI
Affinity DataIC50: 9.70nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448698(5-methyl-N-(2-(4-((5-methylfuran-2-yl)methyl)piper...)copy SMILEScopy InChI
Affinity DataIC50: 10.7nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448670(N-(2-(4-((1H-pyrazol-3-yl)methyl)piperazin-1-yl)-5...)copy SMILEScopy InChI
Affinity DataIC50: 10.9nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448672(N-(2-(4-((1-methyl-1H-pyrazol-3-yl)methyl)piperazi...)copy SMILEScopy InChI
Affinity DataIC50: 11.3nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448684(N-(2-(4-((1H-pyrazol-3-yl)methyl)piperazin-1-yl)-5...)copy SMILEScopy InChI
Affinity DataIC50: 12.7nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM101713(US9695160, 25 | US9796707, Compound 25)copy SMILEScopy InChI
Affinity DataIC50: 13.5nMAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125VTMUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448667(5-(pyridin-4-yl)-N-(2-(4-(thiazol-4-ylmethyl)piper...)copy SMILEScopy InChI
Affinity DataIC50: 13.7nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM101671(US9695160, 18 | US9796707, Compound 18)copy SMILEScopy InChI
Affinity DataIC50: 13.9nMAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125VTMUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM101674(US9695160, 19 | US9796707, Compound 19)copy SMILEScopy InChI
Affinity DataIC50: 14nMT: 2°CAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639MW1US Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM101671(US9695160, 18 | US9796707, Compound 18)copy SMILEScopy InChI
Affinity DataIC50: 14nMT: 2°CAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639MW1US Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM101713(US9695160, 25 | US9796707, Compound 25)copy SMILEScopy InChI
Affinity DataIC50: 14nMT: 2°CAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639MW1US Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448681(N-(2-(4-(thiazol-2-ylmethyl)piperazin-1-yl)-5- (tr...)copy SMILEScopy InChI
Affinity DataIC50: 14.1nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM101674(US9695160, 19 | US9796707, Compound 19)copy SMILEScopy InChI
Affinity DataIC50: 14.1nMAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125VTMUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM101695(US9695160, 22 | US9796707, Compound 22)copy SMILEScopy InChI
Affinity DataIC50: 14.8nMAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125VTMUS Patent
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