Found 50 with Last Name = 'berti' and Initial = 'd' 
Affinity DataKi: 1.70nMAssay Description:Inhibition of MMP-13 catalytic domain (unknown origin) assessed as inhibition of hydrolysis of Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate measured...More data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Inhibition of MMP-12 catalytic domain (unknown origin) assessed as inhibition of hydrolysis of Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate measured...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKi: 16nMAssay Description:Inhibition of MMP-2 (unknown origin) assessed as inhibition of hydrolysis of Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Inhibition of human recombinant MMP-9 catalytic domain (112 to 445 residues) expressed in Escherichia coli assessed as inhibition of hydrolysis of Mc...More data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Inhibition of MMP-12 catalytic domain (unknown origin) assessed as inhibition of hydrolysis of Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate by fluor...More data for this Ligand-Target Pair
Affinity DataKi: 58nMAssay Description:Inhibition of MMP-13 (unknown origin) assessed as inhibition of hydrolysis of Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataKi: 143nMAssay Description:Inhibition of MMP-1 (unknown origin) assessed as inhibition of hydrolysis of Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataKi: 286nMAssay Description:Inhibition of MMP-1 catalytic domain (unknown origin) assessed as inhibition of hydrolysis of Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate measured ...More data for this Ligand-Target Pair
Affinity DataKi: 289nMAssay Description:Inhibition of MMP-9 catalytic domain (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 2.00E+3nMAssay Description:Inhibition of MMP-7 catalytic domain (unknown origin) assessed as inhibition of hydrolysis of Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate measured ...More data for this Ligand-Target Pair
Affinity DataKi: 3.76E+3nMAssay Description:Inhibition of MMP-7 (unknown origin) assessed as inhibition of hydrolysis of Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate by fluorimetric assayMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase type II-alpha regulatory subunit(Homo sapiens)
University of Georgia
Curated by ChEMBL
University of Georgia
Curated by ChEMBL
Affinity DataKd: 80nMAssay Description:Binding affinity to recombinant human full length PKA-R2alpha expressed in Escherichia coli BL21 DE3-RIL cells assessed as reduction in interaction w...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase type II-alpha regulatory subunit(Homo sapiens)
University of Georgia
Curated by ChEMBL
University of Georgia
Curated by ChEMBL
Affinity DataKd: 53nMAssay Description:Binding affinity to recombinant human full length PKA-R2alpha expressed in Escherichia coli BL21 DE3-RIL cells assessed as reduction in interaction w...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
University Hospital Jena
Curated by ChEMBL
University Hospital Jena
Curated by ChEMBL
Affinity DataEC50: 2.75E+3nMAssay Description:Inhibition of 8Fluo-cAMP binding to recombinant human His-tagged EPAC1 (157 to 881 residues) expressed in Escherichia coli measured after 5 mins by f...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase type II-beta regulatory subunit(Homo sapiens (Human))
University of Georgia
Curated by ChEMBL
University of Georgia
Curated by ChEMBL
Affinity DataKd: 75nMAssay Description:Binding affinity to recombinant human full length PKA-R2beta expressed in Escherichia coli BL21 DE3-RIL cells assessed as reduction in interaction wi...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase type II-beta regulatory subunit(Homo sapiens (Human))
University of Georgia
Curated by ChEMBL
University of Georgia
Curated by ChEMBL
Affinity DataKd: 147nMAssay Description:Binding affinity to recombinant human full length PKA-R2beta expressed in Escherichia coli BL21 DE3-RIL cells assessed as reduction in interaction wi...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase type II-alpha regulatory subunit(Homo sapiens)
University of Georgia
Curated by ChEMBL
University of Georgia
Curated by ChEMBL
Affinity DataKd: 283nMAssay Description:Binding affinity to recombinant human full length PKA-R2alpha expressed in Escherichia coli BL21 DE3-RIL cells assessed as reduction in interaction w...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase type II-alpha regulatory subunit(Homo sapiens)
University of Georgia
Curated by ChEMBL
University of Georgia
Curated by ChEMBL
Affinity DataKd: 105nMAssay Description:Binding affinity to recombinant human full length PKA-R2alpha expressed in Escherichia coli BL21 DE3-RIL cells assessed as reduction in interaction w...More data for this Ligand-Target Pair
TargetCyclic nucleotide-gated olfactory channel(Rattus norvegicus)
University Hospital Jena
Curated by ChEMBL
University Hospital Jena
Curated by ChEMBL
Affinity DataEC50: 2.08E+3nMAssay Description:Activation of recombinant rat CNGA2 expressed in Xenopus laevis oocyte assessed as increase in current amplitude by patch-clamp electrophysiology met...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mus musculus)
University Hospital Jena
Curated by ChEMBL
University Hospital Jena
Curated by ChEMBL
Affinity DataEC50: 2.06E+3nMAssay Description:Inhibition of 8Fluo-cAMP binding to DEP domain deficient mouse EPAC2 (280 to 988 residues) measured after 5 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetCyclic nucleotide-gated olfactory channel(Rattus norvegicus)
University Hospital Jena
Curated by ChEMBL
University Hospital Jena
Curated by ChEMBL
Affinity DataEC50: 1.54E+4nMAssay Description:Activation of recombinant rat CNGA2 expressed in Xenopus laevis oocyte assessed as increase in current amplitude by patch-clamp electrophysiology met...More data for this Ligand-Target Pair
TargetCyclic nucleotide-gated olfactory channel(Rattus norvegicus)
University Hospital Jena
Curated by ChEMBL
University Hospital Jena
Curated by ChEMBL
Affinity DataEC50: 5.31E+4nMAssay Description:Activation of recombinant rat CNGA2 expressed in Xenopus laevis oocyte assessed as increase in current amplitude by patch-clamp electrophysiology met...More data for this Ligand-Target Pair
TargetCyclic nucleotide-gated olfactory channel(Rattus norvegicus)
University Hospital Jena
Curated by ChEMBL
University Hospital Jena
Curated by ChEMBL
Affinity DataEC50: 120nMAssay Description:Activation of recombinant rat CNGA2/CNGA4/CNGB1b heterotetramer expressed in Xenopus laevis oocyte assessed as increase in current amplitude by patch...More data for this Ligand-Target Pair
TargetCyclic nucleotide-gated olfactory channel(Rattus norvegicus)
University Hospital Jena
Curated by ChEMBL
University Hospital Jena
Curated by ChEMBL
Affinity DataEC50: 360nMAssay Description:Activation of recombinant rat CNGA2/CNGA4/CNGB1b heterotetramer expressed in Xenopus laevis oocyte assessed as increase in current amplitude by patch...More data for this Ligand-Target Pair
TargetCyclic nucleotide-gated olfactory channel(Rattus norvegicus)
University Hospital Jena
Curated by ChEMBL
University Hospital Jena
Curated by ChEMBL
Affinity DataEC50: 4.98E+3nMAssay Description:Activation of recombinant rat CNGA2/CNGA4/CNGB1b heterotetramer expressed in Xenopus laevis oocyte assessed as increase in current amplitude by patch...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mus musculus)
University Hospital Jena
Curated by ChEMBL
University Hospital Jena
Curated by ChEMBL
Affinity DataEC50: 300nMAssay Description:Inhibition of 8Fluo-cAMP binding to DEP domain deficient mouse EPAC2 (280 to 988 residues) measured after 5 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mus musculus)
University Hospital Jena
Curated by ChEMBL
University Hospital Jena
Curated by ChEMBL
Affinity DataEC50: 3.87E+3nMAssay Description:Inhibition of 8Fluo-cAMP binding to DEP domain deficient mouse EPAC2 (280 to 988 residues) measured after 5 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
University Hospital Jena
Curated by ChEMBL
University Hospital Jena
Curated by ChEMBL
Affinity DataEC50: 530nMAssay Description:Inhibition of 8Fluo-cAMP binding to recombinant human His-tagged EPAC1 (157 to 881 residues) expressed in Escherichia coli measured after 5 mins by f...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
University Hospital Jena
Curated by ChEMBL
University Hospital Jena
Curated by ChEMBL
Affinity DataEC50: 1.09E+3nMAssay Description:Inhibition of 8Fluo-cAMP binding to recombinant human His-tagged EPAC1 (157 to 881 residues) expressed in Escherichia coli measured after 5 mins by f...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
University Hospital Jena
Curated by ChEMBL
University Hospital Jena
Curated by ChEMBL
Affinity DataEC50: 5.62E+3nMAssay Description:Inhibition of 8Fluo-cAMP binding to recombinant human His-tagged EPAC1 (157 to 881 residues) expressed in Escherichia coli measured after 5 mins by f...More data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2(Mus musculus)
University Hospital Jena
Curated by ChEMBL
University Hospital Jena
Curated by ChEMBL
Affinity DataEC50: 15nMAssay Description:Activation of recombinant mouse HCN2 expressed in Xenopus laevis oocyte assessed as increase in current amplitude at -30 mV holding potential by patc...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mus musculus)
University Hospital Jena
Curated by ChEMBL
University Hospital Jena
Curated by ChEMBL
Affinity DataEC50: 2.36E+3nMAssay Description:Inhibition of 8Fluo-cAMP binding to DEP domain deficient mouse EPAC2 (280 to 988 residues) measured after 5 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetCyclic nucleotide-gated olfactory channel(Rattus norvegicus)
University Hospital Jena
Curated by ChEMBL
University Hospital Jena
Curated by ChEMBL
Affinity DataEC50: 6.40E+3nMAssay Description:Activation of recombinant rat CNGA2 expressed in Xenopus laevis oocyte assessed as increase in current amplitude by patch-clamp electrophysiology met...More data for this Ligand-Target Pair
TargetCyclic nucleotide-gated olfactory channel(Rattus norvegicus)
University Hospital Jena
Curated by ChEMBL
University Hospital Jena
Curated by ChEMBL
Affinity DataEC50: 1.60E+3nMAssay Description:Activation of recombinant rat CNGA2/CNGA4/CNGB1b heterotetramer expressed in Xenopus laevis oocyte assessed as increase in current amplitude by patch...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
University Hospital Jena
Curated by ChEMBL
University Hospital Jena
Curated by ChEMBL
Affinity DataEC50: 2.54E+3nMAssay Description:Inhibition of 8Fluo-cAMP binding to recombinant human His-tagged EPAC1 (157 to 881 residues) expressed in Escherichia coli measured after 5 mins by f...More data for this Ligand-Target Pair
TargetCyclic nucleotide-gated olfactory channel(Rattus norvegicus)
University Hospital Jena
Curated by ChEMBL
University Hospital Jena
Curated by ChEMBL
Affinity DataEC50: 540nMAssay Description:Activation of recombinant rat CNGA2 expressed in Xenopus laevis oocyte assessed as increase in current amplitude by patch-clamp electrophysiology met...More data for this Ligand-Target Pair
TargetCyclic nucleotide-gated olfactory channel(Rattus norvegicus)
University Hospital Jena
Curated by ChEMBL
University Hospital Jena
Curated by ChEMBL
Affinity DataEC50: 630nMAssay Description:Activation of recombinant rat CNGA2/CNGA4/CNGB1b heterotetramer expressed in Xenopus laevis oocyte assessed as increase in current amplitude by patch...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mus musculus)
University Hospital Jena
Curated by ChEMBL
University Hospital Jena
Curated by ChEMBL
Affinity DataEC50: 780nMAssay Description:Inhibition of 8Fluo-cAMP binding to DEP domain deficient mouse EPAC2 (280 to 988 residues) measured after 5 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase type II-alpha regulatory subunit(Homo sapiens)
University of Georgia
Curated by ChEMBL
University of Georgia
Curated by ChEMBL
Affinity DataKd: 35nMAssay Description:Binding affinity to recombinant human full length PKA-R2alpha expressed in Escherichia coli BL21 DE3-RIL cells assessed as reduction in interaction w...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase type II-alpha regulatory subunit(Homo sapiens)
University of Georgia
Curated by ChEMBL
University of Georgia
Curated by ChEMBL
Affinity DataKd: 76nMAssay Description:Binding affinity to recombinant human full length PKA-R2alpha expressed in Escherichia coli BL21 DE3-RIL cells assessed as reduction in interaction w...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase type II-alpha regulatory subunit(Homo sapiens)
University of Georgia
Curated by ChEMBL
University of Georgia
Curated by ChEMBL
Affinity DataKd: >730nMAssay Description:Binding affinity to recombinant human full length PKA-R2alpha expressed in Escherichia coli BL21 DE3-RIL cells assessed as reduction in interaction w...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase type II-alpha regulatory subunit(Homo sapiens)
University of Georgia
Curated by ChEMBL
University of Georgia
Curated by ChEMBL
Affinity DataKd: >800nMAssay Description:Binding affinity to recombinant human full length PKA-R2alpha expressed in Escherichia coli BL21 DE3-RIL cells assessed as reduction in interaction w...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase type II-alpha regulatory subunit(Homo sapiens)
University of Georgia
Curated by ChEMBL
University of Georgia
Curated by ChEMBL
Affinity DataKd: 49nMAssay Description:Binding affinity to recombinant human full length PKA-R2alpha expressed in Escherichia coli BL21 DE3-RIL cells assessed as reduction in interaction w...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase type II-beta regulatory subunit(Homo sapiens (Human))
University of Georgia
Curated by ChEMBL
University of Georgia
Curated by ChEMBL
Affinity DataKd: 152nMAssay Description:Binding affinity to recombinant human full length PKA-R2beta expressed in Escherichia coli BL21 DE3-RIL cells assessed as reduction in interaction wi...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase type II-beta regulatory subunit(Homo sapiens (Human))
University of Georgia
Curated by ChEMBL
University of Georgia
Curated by ChEMBL
Affinity DataKd: 131nMAssay Description:Binding affinity to recombinant human full length PKA-R2beta expressed in Escherichia coli BL21 DE3-RIL cells assessed as reduction in interaction wi...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase type II-beta regulatory subunit(Homo sapiens (Human))
University of Georgia
Curated by ChEMBL
University of Georgia
Curated by ChEMBL
Affinity DataKd: 124nMAssay Description:Binding affinity to recombinant human full length PKA-R2beta expressed in Escherichia coli BL21 DE3-RIL cells assessed as reduction in interaction wi...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase type II-beta regulatory subunit(Homo sapiens (Human))
University of Georgia
Curated by ChEMBL
University of Georgia
Curated by ChEMBL
Affinity DataKd: 557nMAssay Description:Binding affinity to recombinant human full length PKA-R2beta expressed in Escherichia coli BL21 DE3-RIL cells assessed as reduction in interaction wi...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase type II-beta regulatory subunit(Homo sapiens (Human))
University of Georgia
Curated by ChEMBL
University of Georgia
Curated by ChEMBL
Affinity DataKd: 257nMAssay Description:Binding affinity to recombinant human full length PKA-R2beta expressed in Escherichia coli BL21 DE3-RIL cells assessed as reduction in interaction wi...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase type II-alpha regulatory subunit(Homo sapiens)
University of Georgia
Curated by ChEMBL
University of Georgia
Curated by ChEMBL
Affinity DataKd: 193nMAssay Description:Binding affinity to recombinant human full length PKA-R2alpha expressed in Escherichia coli BL21 DE3-RIL cells assessed as reduction in interaction w...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase type II-alpha regulatory subunit(Homo sapiens)
University of Georgia
Curated by ChEMBL
University of Georgia
Curated by ChEMBL
Affinity DataKd: 69nMAssay Description:Binding affinity to recombinant human full length PKA-R2alpha expressed in Escherichia coli BL21 DE3-RIL cells assessed as reduction in interaction w...More data for this Ligand-Target Pair
