Compile Data Set for Download or QSAR
Found 378 with Last Name = 'chianelli' and Initial = 'd'
LigandPNGBDBM50575344(CHEMBL4854822)copy SMILES
Affinity DataIC50: 0.540nMAssay Description:Inhibition of RET (658 to 1072) (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0XP8PubMed
LigandPNGBDBM50575348(CHEMBL4853155)copy SMILES
Affinity DataIC50: 0.730nMAssay Description:Inhibition of RET (658 to 1072) (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0XP8PubMed
LigandPNGBDBM50575350(CHEMBL4877264)copy SMILES
Affinity DataIC50: 0.850nMAssay Description:Inhibition of RET (658 to 1072) (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetKinesin-1 heavy chain/Proto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50538514(CHEMBL4644274)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of KIF5B-RET (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-l...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1VJ7PubMed
TargetKinesin-1 heavy chain/Proto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50538516(CHEMBL4643578)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Inhibition of KIF5B-RET (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1VJ7PubMed
LigandPNGBDBM50097956(3-(4-Amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidi...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of RET (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 48 hrs by cell proliferati...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0XP8PubMed
LigandPNGBDBM50575345(CHEMBL4848347)copy SMILES
Affinity DataIC50: 5nMAssay Description:Inhibition of RET (658 to 1072) (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0XP8PubMed
TargetCoiled-coil domain-containing protein 6(Homo sapiens (Human))
The Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50538514(CHEMBL4644274)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMAssay Description:Inhibition of CCDC6/RET (unknown origin) transfected in human LC2/ad cells assessed as reduction in cell viability incubated for 6 days by CellTiter ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1VJ7PubMed
TargetKinesin-1 heavy chain/Proto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50538515(CHEMBL4636056)copy SMILEScopy InChI
Affinity DataIC50: 5.40nMAssay Description:Inhibition of KIF5B-RET (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1VJ7PubMed
LigandPNGBDBM50538508(CHEMBL4634073)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of RET (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucifer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1VJ7PubMed
TargetKinesin-1 heavy chain/Proto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50538508(CHEMBL4634073)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of KIF5B-RET (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1VJ7PubMed
TargetCoiled-coil domain-containing protein 6(Homo sapiens (Human))
The Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50538517(CHEMBL4639022)copy SMILEScopy InChI
Affinity DataIC50: 6.20nMAssay Description:Inhibition of CCDC6/RET (unknown origin) transfected in human LC2/ad cells assessed as reduction in cell viability incubated for 6 days by CellTiter ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1VJ7PubMed
TargetKinesin-1 heavy chain/Proto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50538517(CHEMBL4639022)copy SMILEScopy InChI
Affinity DataIC50: 6.30nMAssay Description:Inhibition of KIF5B-RET (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1VJ7PubMed
TargetKinesin-1 heavy chain/Proto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50097956(3-(4-Amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidi...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of KIF5B-RET fusion protein (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 48 hr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0XP8PubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
The Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50538508(CHEMBL4634073)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of FGFR2 (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1VJ7PubMed
LigandPNGBDBM50575347(CHEMBL4855562)copy SMILES
Affinity DataIC50: 9nMAssay Description:Inhibition of RET (658 to 1072) (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0XP8PubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
The Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50538509(CHEMBL4636995)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of PDGFRalpha (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1VJ7PubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50538508(CHEMBL4634073)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of FGFR1 (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1VJ7PubMed
TargetKinesin-1 heavy chain/Proto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50575343(CHEMBL4858720)copy SMILES
Affinity DataIC50: 11nMAssay Description:Inhibition of KIF5B-RET fusion protein (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 48 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0XP8PubMed
TargetKinesin-1 heavy chain/Proto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50575351(CHEMBL4874648)copy SMILES
Affinity DataIC50: 15nMAssay Description:Inhibition of KIF5B-RET fusion protein (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 48 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0XP8PubMed
TargetCoiled-coil domain-containing protein 6(Homo sapiens (Human))
The Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50538516(CHEMBL4643578)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of CCDC6/RET (unknown origin) transfected in human LC2/ad cells assessed as reduction in cell viability incubated for 6 days by CellTiter ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1VJ7PubMed
TargetCoiled-coil domain-containing protein 6(Homo sapiens (Human))
The Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50538515(CHEMBL4636056)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of CCDC6/RET (unknown origin) transfected in human LC2/ad cells assessed as reduction in cell viability incubated for 6 days by CellTiter ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1VJ7PubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
The Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50538508(CHEMBL4634073)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of PDGFRalpha (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1VJ7PubMed
TargetKinesin-1 heavy chain/Proto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50538508(CHEMBL4634073)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of KIF5B-RET V804M mutant (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1VJ7PubMed
TargetKinesin-1 heavy chain/Proto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50575352(CHEMBL4857808)copy SMILES
Affinity DataIC50: 20nMAssay Description:Inhibition of KIF5B-RET fusion protein (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 48 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0XP8PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
The Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50538508(CHEMBL4634073)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of KIT (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucifer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1VJ7PubMed
TargetKinesin-1 heavy chain/Proto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50575353(CHEMBL4859681)copy SMILES
Affinity DataIC50: 22nMAssay Description:Inhibition of KIF5B-RET fusion protein (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 48 hr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0XP8PubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
The Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50538508(CHEMBL4634073)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of PDGFRbeta (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1VJ7PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
The Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50538508(CHEMBL4634073)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of KDR (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucifer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1VJ7PubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
The Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50575343(CHEMBL4858720)copy SMILES
Affinity DataIC50: 27nMAssay Description:Inhibition of FGFR2 (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 48 hrs by cell prolifera...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0XP8PubMed
TargetKinesin-1 heavy chain/Proto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50538512(CHEMBL4638840)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of KIF5B-RET (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetCoiled-coil domain-containing protein 6(Homo sapiens (Human))
The Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50575351(CHEMBL4874648)copy SMILES
Affinity DataIC50: 35nMAssay Description:Inhibition of CCDC6-RET fusion protein (unknown origin) expressed in human LC-2-ad cells assessed as reduction in cell proliferation incubated for 6 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0XP8PubMed
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
The Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50538508(CHEMBL4634073)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of FGFR4 (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1VJ7PubMed
TargetKinesin-1 heavy chain/Proto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50538507(CHEMBL4640601)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of KIF5B-RET (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1VJ7PubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
The Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50538509(CHEMBL4636995)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of PDGFRbeta (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1VJ7PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))TBA
LigandPNGBDBM50097956(3-(4-Amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidi...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of ROS (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 48 hrs by cell proliferati...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0XP8PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
The Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50575343(CHEMBL4858720)copy SMILES
Affinity DataIC50: 42nMAssay Description:Inhibition of KIT (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 48 hrs by cell proliferati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0XP8PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
The Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50097956(3-(4-Amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidi...)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of KIT (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 48 hrs by cell proliferati...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0XP8PubMed
LigandPNGBDBM50575343(CHEMBL4858720)copy SMILES
Affinity DataIC50: 43nMAssay Description:Inhibition of BCR-ABL (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 48 hrs by cell prolife...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0XP8PubMed
TargetKinesin-1 heavy chain/Proto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50575350(CHEMBL4877264)copy SMILES
Affinity DataIC50: 44nMAssay Description:Inhibition of KIF5B-RET fusion protein (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 48 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetCoiled-coil domain-containing protein 6(Homo sapiens (Human))
The Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50575350(CHEMBL4877264)copy SMILES
Affinity DataIC50: 46nMAssay Description:Inhibition of CCDC6-RET fusion protein (unknown origin) expressed in human LC-2-ad cells assessed as reduction in cell proliferation incubated for 6 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0XP8PubMed
TargetCoiled-coil domain-containing protein 6(Homo sapiens (Human))
The Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50575353(CHEMBL4859681)copy SMILES
Affinity DataIC50: 51nMAssay Description:Inhibition of CCDC6-RET fusion protein (unknown origin) expressed in human LC-2-ad cells assessed as reduction in cell proliferation incubated for 6 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0XP8PubMed
LigandPNGBDBM50575343(CHEMBL4858720)copy SMILES
Affinity DataIC50: 51nMAssay Description:Inhibition of RET (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 48 hrs by cell proliferati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0XP8PubMed
TargetCoiled-coil domain-containing protein 6(Homo sapiens (Human))
The Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50538512(CHEMBL4638840)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of CCDC6/RET (unknown origin) transfected in human LC2/ad cells assessed as reduction in cell viability incubated for 6 days by CellTiter ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1VJ7PubMed
TargetKinesin-1 heavy chain/Proto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50538513(CHEMBL4636800)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of KIF5B-RET (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1VJ7PubMed
LigandPNGBDBM50097956(3-(4-Amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidi...)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Inhibition of BCR-ABL (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 48 hrs by cell prolife...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0XP8PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
The Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50097956(3-(4-Amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidi...)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Inhibition of KDR (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 48 hrs by cell proliferati...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0XP8PubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))TBA
LigandPNGBDBM50097956(3-(4-Amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidi...)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Inhibition of LCK (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 48 hrs by cell proliferati...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0XP8PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))TBA
LigandPNGBDBM50575343(CHEMBL4858720)copy SMILES
Affinity DataIC50: 63nMAssay Description:Inhibition of SRC (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 48 hrs by cell proliferati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0XP8PubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
The Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50538508(CHEMBL4634073)copy SMILEScopy InChI
Affinity DataIC50: 67nMAssay Description:Inhibition of LYN (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucifer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1VJ7PubMed
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