Compile Data Set for Download or QSAR
Found 580 with Last Name = 'diaz' and Initial = 'd'
TargetBcl-2-like protein 1(Homo sapiens (Human))TBA
LigandPNGBDBM209097(US9266877, 43)copy SMILEScopy InChI
Affinity DataKi:  0.00800nMAssay Description:Inhibition of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide probe binding to BCL-xl (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542S8DPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))TBA
LigandPNGBDBM50561528(CHEMBL4762875)copy SMILES
Affinity DataKi: <0.0100nMAssay Description:Inhibition of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide probe binding to BCL-xl (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542S8DPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))TBA
LigandPNGBDBM50162797(CHEMBL3793424)copy SMILEScopy InChI
Affinity DataKi: <0.0100nMAssay Description:Inhibition of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide probe binding to BCL-xl (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542S8DPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))TBA
LigandPNGBDBM209074(US9266877, 20)copy SMILEScopy InChI
Affinity DataKi:  0.0270nMAssay Description:Inhibition of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide probe binding to BCL-xl (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542S8DPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))TBA
LigandPNGBDBM209066(US9266877, 12)copy SMILEScopy InChI
Affinity DataKi:  0.0440nMAssay Description:Inhibition of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide probe binding to BCL-xl (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542S8DPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))TBA
LigandPNGBDBM209055(US9266877, 1)copy SMILEScopy InChI
Affinity DataKi:  0.296nMAssay Description:Inhibition of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide probe binding to BCL-xl (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542S8DPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))TBA
LigandPNGBDBM209179(US9266877, 125)copy SMILEScopy InChI
Affinity DataKi:  0.329nMAssay Description:Inhibition of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide probe binding to BCL-xl (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542S8DPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))TBA
LigandPNGBDBM209073(US9266877, 19)copy SMILEScopy InChI
Affinity DataKi:  0.650nMAssay Description:Inhibition of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide probe binding to BCL-xl (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542S8DPubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Shanghai Chempartner Inc.

Curated by ChEMBL
LigandPNGBDBM50181451(CHEMBL3818265)copy SMILEScopy InChI
Affinity DataKi:  0.950nMAssay Description:Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X88KTPubMed
TargetSerine/threonine-protein kinase PAK 2(Homo sapiens (Human))
Shanghai Chempartner Inc.

Curated by ChEMBL
LigandPNGBDBM50181451(CHEMBL3818265)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibition of human recombinant PAK2 assessed as phosphorylation of coumarin labeled FRET peptide substrate at Ser/Thr19 preincubated for 10 mins fol...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X88KTPubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Shanghai Chempartner Inc.

Curated by ChEMBL
LigandPNGBDBM50181449(CHEMBL3817856)copy SMILEScopy InChI
Affinity DataKi:  2.70nMAssay Description:Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X88KTPubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Shanghai Chempartner Inc.

Curated by ChEMBL
LigandPNGBDBM50182295(CHEMBL3818046)copy SMILEScopy InChI
Affinity DataKi:  3.30nMAssay Description:Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X88KTPubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Shanghai Chempartner Inc.

Curated by ChEMBL
LigandPNGBDBM50182290(CHEMBL3819356)copy SMILEScopy InChI
Affinity DataKi:  3.5nMAssay Description:Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X88KTPubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Shanghai Chempartner Inc.

Curated by ChEMBL
LigandPNGBDBM50148921(CHEMBL3770443)copy SMILEScopy InChI
Affinity DataKi:  3.70nMAssay Description:Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Shanghai Chempartner Inc.

Curated by ChEMBL
LigandPNGBDBM50181450(CHEMBL3818828)copy SMILEScopy InChI
Affinity DataKi:  4.40nMAssay Description:Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X88KTPubMed
TargetSerine/threonine-protein kinase PAK 2(Homo sapiens (Human))
Shanghai Chempartner Inc.

Curated by ChEMBL
LigandPNGBDBM50182399(CHEMBL3818479)copy SMILEScopy InChI
Affinity DataKi:  4.60nMAssay Description:Inhibition of human recombinant PAK2 assessed as phosphorylation of coumarin labeled FRET peptide substrate at Ser/Thr19 preincubated for 10 mins fol...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X88KTPubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Shanghai Chempartner Inc.

Curated by ChEMBL
LigandPNGBDBM50182287(CHEMBL3818592)copy SMILEScopy InChI
Affinity DataKi:  4.60nMAssay Description:Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ...More data for this Ligand-Target Pair
TargetBcl-2-like protein 1(Homo sapiens (Human))TBA
LigandPNGBDBM209056(US9266877, 2)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Inhibition of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide probe binding to BCL-xl (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542S8DPubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Shanghai Chempartner Inc.

Curated by ChEMBL
LigandPNGBDBM50182399(CHEMBL3818479)copy SMILEScopy InChI
Affinity DataKi:  5.20nMAssay Description:Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X88KTPubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Shanghai Chempartner Inc.

Curated by ChEMBL
LigandPNGBDBM50182399(CHEMBL3818479)copy SMILEScopy InChI
Affinity DataKi:  5.20nMAssay Description:Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X88KTPubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Shanghai Chempartner Inc.

Curated by ChEMBL
LigandPNGBDBM50182405(CHEMBL3818016)copy SMILEScopy InChI
Affinity DataKi:  5.90nMAssay Description:Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X88KTPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))TBA
LigandPNGBDBM209176(US9266877, 122)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:Inhibition of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide probe binding to BCL-xl (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542S8DPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))TBA
LigandPNGBDBM50162797(CHEMBL3793424)copy SMILEScopy InChI
Affinity DataKi:  6.10nMAssay Description:Inhibition of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) F-Bak(GQVGRQLAIIGDK(6-FAM)INR-amide) binding to BCL2 (unknown origin) incubated for 1 hr by TR-FR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542S8DPubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Shanghai Chempartner Inc.

Curated by ChEMBL
LigandPNGBDBM50182294(CHEMBL3817984)copy SMILEScopy InChI
Affinity DataKi:  6.30nMAssay Description:Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X88KTPubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Shanghai Chempartner Inc.

Curated by ChEMBL
LigandPNGBDBM50182288(CHEMBL3818432)copy SMILEScopy InChI
Affinity DataKi:  6.70nMAssay Description:Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X88KTPubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Shanghai Chempartner Inc.

Curated by ChEMBL
LigandPNGBDBM50182293(CHEMBL3817890)copy SMILEScopy InChI
Affinity DataKi:  8nMAssay Description:Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X88KTPubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Shanghai Chempartner Inc.

Curated by ChEMBL
LigandPNGBDBM50181448(CHEMBL3818233)copy SMILEScopy InChI
Affinity DataKi:  9nMAssay Description:Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X88KTPubMed
TargetSerine/threonine-protein kinase PAK 2(Homo sapiens (Human))
Shanghai Chempartner Inc.

Curated by ChEMBL
LigandPNGBDBM50181452(CHEMBL3819118)copy SMILEScopy InChI
Affinity DataKi:  9.5nMAssay Description:Inhibition of human recombinant PAK2 assessed as phosphorylation of coumarin labeled FRET peptide substrate at Ser/Thr19 preincubated for 10 mins fol...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X88KTPubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Shanghai Chempartner Inc.

Curated by ChEMBL
LigandPNGBDBM50181452(CHEMBL3819118)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X88KTPubMed
TargetSerine/threonine-protein kinase PAK 2(Homo sapiens (Human))
Shanghai Chempartner Inc.

Curated by ChEMBL
LigandPNGBDBM50148921(CHEMBL3770443)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:Inhibition of human recombinant PAK2 assessed as phosphorylation of coumarin labeled FRET peptide substrate at Ser/Thr19 preincubated for 10 mins fol...More data for this Ligand-Target Pair
TargetBcl-2-like protein 1(Homo sapiens (Human))TBA
LigandPNGBDBM50020933(CHEMBL3287296)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:Inhibition of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide probe binding to BCL-xl (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542S8DPubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Shanghai Chempartner Inc.

Curated by ChEMBL
LigandPNGBDBM50182292(CHEMBL3818273)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X88KTPubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Shanghai Chempartner Inc.

Curated by ChEMBL
LigandPNGBDBM50182297(CHEMBL3818372)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X88KTPubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Shanghai Chempartner Inc.

Curated by ChEMBL
LigandPNGBDBM50182291(CHEMBL3818138)copy SMILEScopy InChI
Affinity DataKi:  17nMAssay Description:Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X88KTPubMed
TargetSerine/threonine-protein kinase PAK 2(Homo sapiens (Human))
Shanghai Chempartner Inc.

Curated by ChEMBL
LigandPNGBDBM50182294(CHEMBL3817984)copy SMILEScopy InChI
Affinity DataKi:  21nMAssay Description:Inhibition of human recombinant PAK2 assessed as phosphorylation of coumarin labeled FRET peptide substrate at Ser/Thr19 preincubated for 10 mins fol...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X88KTPubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Shanghai Chempartner Inc.

Curated by ChEMBL
LigandPNGBDBM50182402(CHEMBL3819447)copy SMILEScopy InChI
Affinity DataKi:  22nMAssay Description:Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X88KTPubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Shanghai Chempartner Inc.

Curated by ChEMBL
LigandPNGBDBM50148931(CHEMBL3770186)copy SMILEScopy InChI
Affinity DataKi:  23nMAssay Description:Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ...More data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))TBA
LigandPNGBDBM209097(US9266877, 43)copy SMILEScopy InChI
Affinity DataKi:  29nMAssay Description:Inhibition of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) F-Bak(GQVGRQLAIIGDK(6-FAM)INR-amide) binding to BCL2 (unknown origin) incubated for 1 hr by TR-FR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542S8DPubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Shanghai Chempartner Inc.

Curated by ChEMBL
LigandPNGBDBM50182289(CHEMBL3818326)copy SMILEScopy InChI
Affinity DataKi:  36nMAssay Description:Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X88KTPubMed
TargetSerine/threonine-protein kinase PAK 2(Homo sapiens (Human))
Shanghai Chempartner Inc.

Curated by ChEMBL
LigandPNGBDBM50182402(CHEMBL3819447)copy SMILEScopy InChI
Affinity DataKi:  39nMAssay Description:Inhibition of human recombinant PAK2 assessed as phosphorylation of coumarin labeled FRET peptide substrate at Ser/Thr19 preincubated for 10 mins fol...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X88KTPubMed
TargetSerine/threonine-protein kinase PAK 2(Homo sapiens (Human))
Shanghai Chempartner Inc.

Curated by ChEMBL
LigandPNGBDBM50148931(CHEMBL3770186)copy SMILEScopy InChI
Affinity DataKi:  48nMAssay Description:Inhibition of human recombinant PAK2 assessed as phosphorylation of coumarin labeled FRET peptide substrate at Ser/Thr19 preincubated for 10 mins fol...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Shanghai Chempartner Inc.

Curated by ChEMBL
LigandPNGBDBM50182354(CHEMBL3818217)copy SMILEScopy InChI
Affinity DataKi:  56nMAssay Description:Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X88KTPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))TBA
LigandPNGBDBM50020930(CHEMBL3287293)copy SMILEScopy InChI
Affinity DataKi:  65nMAssay Description:Inhibition of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide probe binding to BCL-xl (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542S8DPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))TBA
LigandPNGBDBM209074(US9266877, 20)copy SMILEScopy InChI
Affinity DataKi:  70nMAssay Description:Inhibition of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) F-Bak(GQVGRQLAIIGDK(6-FAM)INR-amide) binding to BCL2 (unknown origin) incubated for 1 hr by TR-FR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542S8DPubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Shanghai Chempartner Inc.

Curated by ChEMBL
LigandPNGBDBM50182309(CHEMBL3818571)copy SMILEScopy InChI
Affinity DataKi:  89nMAssay Description:Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X88KTPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))TBA
LigandPNGBDBM209055(US9266877, 1)copy SMILEScopy InChI
Affinity DataKi:  117nMAssay Description:Inhibition of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) F-Bak(GQVGRQLAIIGDK(6-FAM)INR-amide) binding to BCL2 (unknown origin) incubated for 1 hr by TR-FR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542S8DPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))TBA
LigandPNGBDBM209179(US9266877, 125)copy SMILEScopy InChI
Affinity DataKi:  119nMAssay Description:Inhibition of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) F-Bak(GQVGRQLAIIGDK(6-FAM)INR-amide) binding to BCL2 (unknown origin) incubated for 1 hr by TR-FR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542S8DPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50033887(CHEMBL3358611)copy SMILEScopy InChI
Affinity DataKi:  146nMAssay Description:Inhibition of STAT5B SH2 domain (unknown origin)-5-FAM-GpYLVLDKW interaction compound treated for 15 mins by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2BJJPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))TBA
LigandPNGBDBM50020929(CHEMBL3287292)copy SMILEScopy InChI
Affinity DataKi:  164nMAssay Description:Inhibition of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide probe binding to BCL-xl (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542S8DPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))TBA
LigandPNGBDBM209176(US9266877, 122)copy SMILEScopy InChI
Affinity DataKi:  348nMAssay Description:Inhibition of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) F-Bak(GQVGRQLAIIGDK(6-FAM)INR-amide) binding to BCL2 (unknown origin) incubated for 1 hr by TR-FR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542S8DPubMed
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