Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Pfizer Central Research
Curated by ChEMBL
Pfizer Central Research
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Binding affinity for human 5 alpha reductase 1 isozymeMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Pfizer Central Research
Curated by ChEMBL
Pfizer Central Research
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Binding affinity for human 5 alpha reductase 1 isozymeMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Pfizer Central Research
Curated by ChEMBL
Pfizer Central Research
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Binding affinity for human 5 alpha reductase 1 isozymeMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Pfizer Central Research
Curated by ChEMBL
Pfizer Central Research
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Binding affinity for human 5 alpha reductase 1 isozymeMore data for this Ligand-Target Pair
Target3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1(Homo sapiens (Human))
Pfizer Central Research
Curated by ChEMBL
Pfizer Central Research
Curated by ChEMBL
Affinity DataKi: 7.80nMAssay Description:Binding affinity for 3-beta-hydroxysteroid dehydrogenaseMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Rattus norvegicus)
Pfizer Central Research
Curated by ChEMBL
Pfizer Central Research
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Binding affinity on rat 5-alpha reductase-1 isozymeMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Pfizer Central Research
Curated by ChEMBL
Pfizer Central Research
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Binding affinity for human 5 alpha reductase 1 isozymeMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Pfizer Central Research
Curated by ChEMBL
Pfizer Central Research
Curated by ChEMBL
Affinity DataKi: 8.80nMAssay Description:Binding affinity for human 5 alpha reductase 1 isozymeMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Pfizer Central Research
Curated by ChEMBL
Pfizer Central Research
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Inhibitory concentration on human 5alpha reductase 2 isozymeMore data for this Ligand-Target Pair
Target3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1(Homo sapiens (Human))
Pfizer Central Research
Curated by ChEMBL
Pfizer Central Research
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Binding affinity for 3-beta-hydroxysteroid dehydrogenaseMore data for this Ligand-Target Pair
Target3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1(Homo sapiens (Human))
Pfizer Central Research
Curated by ChEMBL
Pfizer Central Research
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Binding affinity for 3-beta-hydroxysteroid dehydrogenaseMore data for this Ligand-Target Pair
Target3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1(Homo sapiens (Human))
Pfizer Central Research
Curated by ChEMBL
Pfizer Central Research
Curated by ChEMBL
Affinity DataKi: 19nMAssay Description:Binding affinity for 3-beta-hydroxysteroid dehydrogenaseMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Pfizer Central Research
Curated by ChEMBL
Pfizer Central Research
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Binding affinity for human 5 alpha reductase 1 isozymeMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Pfizer Central Research
Curated by ChEMBL
Pfizer Central Research
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Binding affinity for human 5 alpha reductase 1 isozymeMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Pfizer Central Research
Curated by ChEMBL
Pfizer Central Research
Curated by ChEMBL
Affinity DataKi: 40nMAssay Description:Inhibitory concentration on human 5alpha reductase 2 isozymeMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Binding affinity was tested on human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
Target3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1(Homo sapiens (Human))
Pfizer Central Research
Curated by ChEMBL
Pfizer Central Research
Curated by ChEMBL
Affinity DataKi: 150nMAssay Description:Binding affinity for 3-beta-hydroxysteroid dehydrogenaseMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Pfizer Central Research
Curated by ChEMBL
Pfizer Central Research
Curated by ChEMBL
Affinity DataKi: 150nMAssay Description:Binding affinity for human 5 alpha reductase 1 isozymeMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Pfizer Central Research
Curated by ChEMBL
Pfizer Central Research
Curated by ChEMBL
Affinity DataKi: 150nMAssay Description:Binding affinity for human 5 alpha reductase 1 isozymeMore data for this Ligand-Target Pair
Target3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1(Homo sapiens (Human))
Pfizer Central Research
Curated by ChEMBL
Pfizer Central Research
Curated by ChEMBL
Affinity DataKi: 160nMAssay Description:Binding affinity for 3-beta-hydroxysteroid dehydrogenaseMore data for this Ligand-Target Pair
Target3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1(Homo sapiens (Human))
Pfizer Central Research
Curated by ChEMBL
Pfizer Central Research
Curated by ChEMBL
Affinity DataKi: 180nMAssay Description:Binding affinity for 3-beta-hydroxysteroid dehydrogenaseMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Pfizer Central Research
Curated by ChEMBL
Pfizer Central Research
Curated by ChEMBL
Affinity DataKi: 180nMAssay Description:Binding affinity for human 5 alpha reductase 1 isozymeMore data for this Ligand-Target Pair
Target3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1(Homo sapiens (Human))
Pfizer Central Research
Curated by ChEMBL
Pfizer Central Research
Curated by ChEMBL
Affinity DataKi: 190nMAssay Description:Binding affinity for 3-beta-hydroxysteroid dehydrogenaseMore data for this Ligand-Target Pair
Target3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1(Homo sapiens (Human))
Pfizer Central Research
Curated by ChEMBL
Pfizer Central Research
Curated by ChEMBL
Affinity DataKi: 190nMAssay Description:Binding affinity for 3-beta-hydroxysteroid dehydrogenaseMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Pfizer Central Research
Curated by ChEMBL
Pfizer Central Research
Curated by ChEMBL
Affinity DataKi: 240nMAssay Description:Binding affinity for human 5 alpha reductase 1 isozymeMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Pfizer Central Research
Curated by ChEMBL
Pfizer Central Research
Curated by ChEMBL
Affinity DataKi: 260nMAssay Description:Binding affinity on human prostatic 5-alpha reductase-2 isozymeMore data for this Ligand-Target Pair
Target3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1(Homo sapiens (Human))
Pfizer Central Research
Curated by ChEMBL
Pfizer Central Research
Curated by ChEMBL
Affinity DataKi: 490nMAssay Description:Binding affinity for 3-beta-hydroxysteroid dehydrogenaseMore data for this Ligand-Target Pair
Target3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1(Homo sapiens (Human))
Pfizer Central Research
Curated by ChEMBL
Pfizer Central Research
Curated by ChEMBL
Affinity DataKi: 510nMAssay Description:Binding affinity for 3-beta-hydroxysteroid dehydrogenaseMore data for this Ligand-Target Pair
Target3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1(Homo sapiens (Human))
Pfizer Central Research
Curated by ChEMBL
Pfizer Central Research
Curated by ChEMBL
Affinity DataKi: 1.60E+3nMAssay Description:Binding affinity for 3-beta-hydroxysteroid dehydrogenaseMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Pfizer Central Research
Curated by ChEMBL
Pfizer Central Research
Curated by ChEMBL
Affinity DataKi: 2.20E+3nMAssay Description:Binding affinity for human 5 alpha reductase 1 isozymeMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Pfizer Central Research
Curated by ChEMBL
Pfizer Central Research
Curated by ChEMBL
Affinity DataKi: >2.50E+3nMAssay Description:Inhibitory concentration on human 5-alpha reductase 1 isozymeMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Rattus norvegicus)
Pfizer Central Research
Curated by ChEMBL
Pfizer Central Research
Curated by ChEMBL
Affinity DataKi: 1.00E+4nMAssay Description:Binding affinity on rat 5-alpha reductase-2 isozymeMore data for this Ligand-Target Pair
Target3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1(Homo sapiens (Human))
Pfizer Central Research
Curated by ChEMBL
Pfizer Central Research
Curated by ChEMBL
Affinity DataKi: 1.10E+4nMAssay Description:Binding affinity for 3-beta-hydroxysteroid dehydrogenaseMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 0.00700nMAssay Description:Inhibition of PDE5 in human platelet by assessed as hydrolysis of [3H]cGMP scintillation proximity assayMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of PDE5 in human platelet by assessed as hydrolysis of [3H]cGMP scintillation proximity assayMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of PDE5 in human platelet by assessed as hydrolysis of [3H]cGMP scintillation proximity assayMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of PDE5 in human platelet by assessed as hydrolysis of [3H]cGMP scintillation proximity assayMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of PDE5 in human platelet by assessed as hydrolysis of [3H]cGMP scintillation proximity assayMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of PDE5 in human platelet by assessed as hydrolysis of [3H]cGMP scintillation proximity assayMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of PDE5 in human platelet by assessed as hydrolysis of [3H]cGMP scintillation proximity assayMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of PDE5 in human platelet by assessed as hydrolysis of [3H]cGMP scintillation proximity assayMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of PDE5 in human platelet by assessed as hydrolysis of [3H]cGMP scintillation proximity assayMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of PDE5 in human platelet by assessed as hydrolysis of [3H]cGMP scintillation proximity assayMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Pfizer Central Research
Curated by ChEMBL
Pfizer Central Research
Curated by ChEMBL
Affinity DataIC50: 0.120nMAssay Description:Binding affinity for human 5-alpha reductase 2 isozymeMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Pfizer Central Research
Curated by ChEMBL
Pfizer Central Research
Curated by ChEMBL
Affinity DataIC50: 0.180nMAssay Description:Binding affinity for human 5-alpha reductase 2 isozymeMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 0.190nMAssay Description:Inhibition of PDE5 in human platelet by assessed as hydrolysis of [3H]cGMP scintillation proximity assayMore data for this Ligand-Target Pair
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