TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 7.05nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition assay using ECE.More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition assay using ECE.More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 11.1nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 11.1nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 14.6nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 15.4nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 15.7nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 17.0nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 17.4nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 18.4nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 19.7nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 21.3nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 25nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 29nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 33.6nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derivedMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 53.7nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 63nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
Affinity DataIC50: 66nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derivedMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 79.9nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 81nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 98.2nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 109nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 109nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derivedMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derivedMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 165nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition assay using ECE.More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition assay using ECE.More data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 237nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 248nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 359nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
Affinity DataIC50: 390nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 410nMAssay Description:Inhibition assay using ECE.More data for this Ligand-Target Pair
Affinity DataIC50: 440nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 483nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
Affinity DataIC50: 650nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 660nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 740nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 850nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
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