Compile Data Set for Download or QSAR
Found 68 with Last Name = 'heimbach' and Initial = 'd'
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH

US Patent
LigandPNGBDBM150313(US8987248, 106)copy SMILEScopy InChI
Affinity DataIC50: 7.05nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QC027WUS Patent
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Bayer HealthCare AG

LigandPNGBDBM97371(ECE Inhibitor, 14)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition assay using ECE.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ604CPubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Bayer HealthCare AG

LigandPNGBDBM50171626(5-(3,3-Dimethyl-butyrylamino)-1-(2-fluoro-benzyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition assay using ECE.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ604CPubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH

US Patent
LigandPNGBDBM150314(US8987248, 115)copy SMILEScopy InChI
Affinity DataIC50: 11.1nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QC027WUS Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH

US Patent
LigandPNGBDBM150322(US8987248, 156)copy SMILEScopy InChI
Affinity DataIC50: 11.1nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QC027WUS Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH

US Patent
LigandPNGBDBM150319(US8987248, 133)copy SMILEScopy InChI
Affinity DataIC50: 14.6nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QC027WUS Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH

US Patent
LigandPNGBDBM150320(US8987248, 134)copy SMILEScopy InChI
Affinity DataIC50: 15.4nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QC027WUS Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH

US Patent
LigandPNGBDBM150315(US8987248, 119)copy SMILEScopy InChI
Affinity DataIC50: 15.7nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QC027WUS Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH

US Patent
LigandPNGBDBM150317(US8987248, 128)copy SMILEScopy InChI
Affinity DataIC50: 17.0nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QC027WUS Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH

US Patent
LigandPNGBDBM150307(US8987248, 91)copy SMILEScopy InChI
Affinity DataIC50: 17.4nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QC027WUS Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH

US Patent
LigandPNGBDBM150312(US8987248, 105)copy SMILEScopy InChI
Affinity DataIC50: 18.4nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QC027WUS Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH

US Patent
LigandPNGBDBM150305(US8987248, 83)copy SMILEScopy InChI
Affinity DataIC50: 19.7nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QC027WUS Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH

US Patent
LigandPNGBDBM150324(BDBM150325 | US8987248, 170)copy SMILEScopy InChI
Affinity DataIC50: 21.3nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QC027WUS Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH

US Patent
LigandPNGBDBM150323(US8987248, 162)copy SMILEScopy InChI
Affinity DataIC50: 25nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QC027WUS Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH

US Patent
LigandPNGBDBM150301(US8987248, 7)copy SMILEScopy InChI
Affinity DataIC50: 29nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QC027WUS Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH

US Patent
LigandPNGBDBM150318(US8987248, 129)copy SMILEScopy InChI
Affinity DataIC50: 33.6nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QC027WUS Patent
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
BAYER HealthCare AG

Curated by ChEMBL
LigandPNGBDBM50171626(5-(3,3-Dimethyl-butyrylamino)-1-(2-fluoro-benzyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derivedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H994R9PubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH

US Patent
LigandPNGBDBM150321(US8987248, 141)copy SMILEScopy InChI
Affinity DataIC50: 53.7nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QC027WUS Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH

US Patent
LigandPNGBDBM150326(US8987248, 178)copy SMILEScopy InChI
Affinity DataIC50: 63nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QC027WUS Patent
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
BAYER HealthCare AG

Curated by ChEMBL
LigandPNGBDBM50171614(5-(3,3-Dimethyl-butyrylamino)-1-(2-fluoro-benzyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 66nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derivedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H994R9PubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH

US Patent
LigandPNGBDBM150316(US8987248, 121)copy SMILEScopy InChI
Affinity DataIC50: 79.9nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QC027WUS Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH

US Patent
LigandPNGBDBM150324(BDBM150325 | US8987248, 170)copy SMILEScopy InChI
Affinity DataIC50: 81nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QC027WUS Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH

US Patent
LigandPNGBDBM150304(US8987248, 36)copy SMILEScopy InChI
Affinity DataIC50: 98.2nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QC027WUS Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH

US Patent
LigandPNGBDBM150302(US8987248, 8)copy SMILEScopy InChI
Affinity DataIC50: 109nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QC027WUS Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH

US Patent
LigandPNGBDBM150309(US8987248, 97)copy SMILEScopy InChI
Affinity DataIC50: 109nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QC027WUS Patent
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
BAYER HealthCare AG

Curated by ChEMBL
LigandPNGBDBM50171633(1-(2-Fluoro-benzyl)-5-[2-(1-methyl-cyclopentyl)-ac...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H994R9PubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
BAYER HealthCare AG

Curated by ChEMBL
LigandPNGBDBM50171611(5-(3,3-Dimethyl-butyrylamino)-1-(2-fluoro-benzyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derivedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H994R9PubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
BAYER HealthCare AG

Curated by ChEMBL
LigandPNGBDBM50171630(5-(3,3-Dimethyl-butyrylamino)-1-(2-fluoro-benzyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H994R9PubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
BAYER HealthCare AG

Curated by ChEMBL
LigandPNGBDBM50171629(5-(3,3-Dimethyl-butyrylamino)-1-(2-fluoro-benzyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derivedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H994R9PubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH

US Patent
LigandPNGBDBM150310(US8987248, 102)copy SMILEScopy InChI
Affinity DataIC50: 165nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QC027WUS Patent
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
BAYER HealthCare AG

Curated by ChEMBL
LigandPNGBDBM50171615(5-(3,3-Dimethyl-butyrylamino)-1-(2-fluoro-benzyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H994R9PubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
BAYER HealthCare AG

Curated by ChEMBL
LigandPNGBDBM50171613(5-(3,3-Dimethyl-butyrylamino)-1-(2-trifluoromethyl...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H994R9PubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Bayer HealthCare AG

LigandPNGBDBM97370(ECE Inhibitor, 13)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition assay using ECE.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ604CPubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
BAYER HealthCare AG

Curated by ChEMBL
LigandPNGBDBM50171643(5-(3,3-Dimethyl-butyrylamino)-1-(2-fluoro-benzyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H994R9PubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
BAYER HealthCare AG

Curated by ChEMBL
LigandPNGBDBM50171628(5-(3,3-Dimethyl-butyrylamino)-1-(2-fluoro-benzyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H994R9PubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
BAYER HealthCare AG

Curated by ChEMBL
LigandPNGBDBM50171624(5-(3,3-Dimethyl-butyrylamino)-1-(2-fluoro-benzyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H994R9PubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Bayer HealthCare AG

LigandPNGBDBM50171642(5-(3,3-Dimethyl-butyrylamino)-1-(2-fluoro-benzyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition assay using ECE.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ604CPubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
BAYER HealthCare AG

Curated by ChEMBL
LigandPNGBDBM50171637(5-(3,3-Dimethyl-butyrylamino)-1-(2-fluoro-benzyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H994R9PubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH

US Patent
LigandPNGBDBM150308(US8987248, 95)copy SMILEScopy InChI
Affinity DataIC50: 237nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QC027WUS Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH

US Patent
LigandPNGBDBM150311(US8987248, 104)copy SMILEScopy InChI
Affinity DataIC50: 248nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QC027WUS Patent
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
BAYER HealthCare AG

Curated by ChEMBL
LigandPNGBDBM50171612(5-(2-Bicyclo[2.2.1]hept-2-yl-acetylamino)-1-(2-flu...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H994R9PubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH

US Patent
LigandPNGBDBM150306(US8987248, 90)copy SMILEScopy InChI
Affinity DataIC50: 359nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QC027WUS Patent
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
BAYER HealthCare AG

Curated by ChEMBL
LigandPNGBDBM50171631(4-{[5-(3,3-Dimethyl-butyrylamino)-1-(2-fluoro-benz...)copy SMILEScopy InChI
Affinity DataIC50: 390nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H994R9PubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Bayer HealthCare AG

LigandPNGBDBM97369(ECE Inhibitor, 10)copy SMILEScopy InChI
Affinity DataIC50: 410nMAssay Description:Inhibition assay using ECE.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ604CPubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
BAYER HealthCare AG

Curated by ChEMBL
LigandPNGBDBM50171642(5-(3,3-Dimethyl-butyrylamino)-1-(2-fluoro-benzyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 440nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H994R9PubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH

US Patent
LigandPNGBDBM150303(US8987248, 18)copy SMILEScopy InChI
Affinity DataIC50: 483nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QC027WUS Patent
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
BAYER HealthCare AG

Curated by ChEMBL
LigandPNGBDBM50171632(1-(2,6-Difluoro-benzyl)-5-(3,3-dimethyl-butyrylami...)copy SMILEScopy InChI
Affinity DataIC50: 650nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H994R9PubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
BAYER HealthCare AG

Curated by ChEMBL
LigandPNGBDBM50171616(5-(3,3-Dimethyl-thiobutyrylamino)-1-(2-fluoro-benz...)copy SMILEScopy InChI
Affinity DataIC50: 660nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H994R9PubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
BAYER HealthCare AG

Curated by ChEMBL
LigandPNGBDBM50171640(5-(4,4-Dimethyl-pentanoylamino)-1-(2-fluoro-benzyl...)copy SMILEScopy InChI
Affinity DataIC50: 740nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H994R9PubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
BAYER HealthCare AG

Curated by ChEMBL
LigandPNGBDBM50171638(5-(3,3-Dimethyl-butyrylamino)-1-(2-fluoro-benzyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 850nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H994R9PubMed
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