Compile Data Set for Download or QSAR
Found 274 with Last Name = 'keith' and Initial = 'd'
TargetBifunctional glutamate/proline--tRNA ligase(Homo sapiens (Human))
Cubist Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50097096(2-(4-Bromo-phenyl)-6-chloro-8-methyl-quinoline-4-c...)copy SMILEScopy InChI
Affinity DataKi:  5.10nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q23ZH8PubMed
TargetBifunctional glutamate/proline--tRNA ligase(Homo sapiens (Human))
Cubist Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50097096(2-(4-Bromo-phenyl)-6-chloro-8-methyl-quinoline-4-c...)copy SMILEScopy InChI
Affinity DataKi:  15nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q23ZH8PubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50265453((S)-2-(3-((S)-1-Carboxy-5-(3-(4-bromophenyl)ureido...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V987ZZPubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50265381((S)-2-(3-((S)-1-Carboxy-5-(4-chlorobenzylamino)pen...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V987ZZPubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50140706(5-(3,4-dichlorophenyl)-3-phenyl-(3R,3aR,6aS)-spiro...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against human phenylalanyl-tRNA synthetase was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7VDSPubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50265471((S)-2-(3-((S)-1-Carboxy-5-(3-(4-fluorophenyl)ureid...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V987ZZPubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50265454((S)-2-(3-((S)-1-Carboxy-5-(3-(4-chlorophenyl)ureid...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V987ZZPubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50140706(5-(3,4-dichlorophenyl)-3-phenyl-(3R,3aR,6aS)-spiro...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7VDSPubMed
TargetProline--tRNA ligase, cytoplasmic(Candida albicans)
Cubist Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50097096(2-(4-Bromo-phenyl)-6-chloro-8-methyl-quinoline-4-c...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q23ZH8PubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50265474((S)-2-(3-((S)-1-Carboxy-5-(4-iodophenylsulfonamido...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V987ZZPubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50265783((S)-2-(3-((S)-1-Carboxy-5-(3-(4-iodophenyl)ureido)...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V987ZZPubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50265472((S)-2-(3-((S)-1-Carboxy-5-(3-phenylureido)pentyl)u...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V987ZZPubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50143330((S)-1-{1-[2-(2,4-Dichloro-phenyl)-5-oxo-oxazol-(4Z...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4Q2FPubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50265473((9S,13S)-1-(3-iodophenyl)-3,11-dioxo-2,4,10,12-tet...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V987ZZPubMed
TargetProline--tRNA ligase, cytoplasmic(Candida albicans)
Cubist Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50097082(2-(4-Bromo-phenyl)-6-iodo-quinoline-4-carboxylic a...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q23ZH8PubMed
TargetProline--tRNA ligase, cytoplasmic(Candida albicans)
Cubist Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50097095(2-(4-Bromo-phenyl)-6-chloro-8-methyl-quinoline-4-c...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q23ZH8PubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50265377((S)-2-(3-((S)-1-Carboxy-5-(4-iodobenzylamino)penty...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V987ZZPubMed
TargetProline--tRNA ligase, cytoplasmic(Candida albicans)
Cubist Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50097105(6-Bromo-2-(4-bromo-phenyl)-quinoline-4-carboxylic ...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q23ZH8PubMed
TargetProline--tRNA ligase, cytoplasmic(Candida albicans)
Cubist Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50097106(2-(4-Bromo-phenyl)-8-chloro-6-methyl-quinoline-4-c...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q23ZH8PubMed
TargetProline--tRNA ligase, cytoplasmic(Candida albicans)
Cubist Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50097090(2-(4-Bromo-phenyl)-6-chloro-quinoline-4-carboxylic...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q23ZH8PubMed
TargetProline--tRNA ligase, cytoplasmic(Candida albicans)
Cubist Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50097086(2-(4-Bromo-phenyl)-6-chloro-8-methyl-quinoline-4-c...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q23ZH8PubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50265378((S)-2-(3-((S)-1-Carboxy-5-(2-iodobenzylamino)penty...)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V987ZZPubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50143333((S)-1-{1-[2-(2,4-Dichloro-phenyl)-5-oxo-oxazol-(4Z...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4Q2FPubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50140709(5'-(3,4-dichlorophenyl)-3'-phenyl-(3'R,3a'S,6a'R)-...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7VDSPubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50140709(5'-(3,4-dichlorophenyl)-3'-phenyl-(3'R,3a'S,6a'R)-...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7VDSPubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50265380((S)-2-(3-((S)-1-Carboxy-5-(4-bromobenzylamino)pent...)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V987ZZPubMed
TargetProline--tRNA ligase, cytoplasmic(Candida albicans)
Cubist Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50097113(2-(4-Bromo-phenyl)-6-trifluoromethoxy-quinoline-4-...)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q23ZH8PubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50143329((S)-1-[2-(2,4-Dichloro-phenyl)-5-oxo-oxazol-(4Z)-y...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of human methionyl-tRNA synthetase (fMetRS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4Q2FPubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50140707(5-(3-chloro-4-methylphenyl)-3-phenyl-(3R,3aS,6aR)-...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7VDSPubMed
TargetProline--tRNA ligase, cytoplasmic(Candida albicans)
Cubist Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50097102(2-(4-Bromo-phenyl)-6-chloro-8-methyl-quinoline-4-c...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q23ZH8PubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50143334((S)-1-{1-[2-(4-Bromo-phenyl)-5-oxo-oxazol-(4Z)-yli...)copy SMILEScopy InChI
Affinity DataIC50: 87nMAssay Description:Inhibition of Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4Q2FPubMed
TargetProline--tRNA ligase, cytoplasmic(Candida albicans)
Cubist Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50097107(2-(4-Bromo-phenyl)-7-fluoro-8-methyl-quinoline-4-c...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q23ZH8PubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50129541(3-[5-(2',4'-Dichloro-biphenyl-4-yl)-3-tetrazol-1-y...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7TCMPubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50129527(5-(2',4'-Dichloro-biphenyl-4-yl)-1-pyridin-3-yl-1H...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against human methionyl-tRNA synthetase (hMetRS).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7TCMPubMed
TargetProline--tRNA ligase, cytoplasmic(Candida albicans)
Cubist Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50097091(2-(4-Bromo-phenyl)-5,7-dichloro-quinoline-4-carbox...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q23ZH8PubMed
TargetProline--tRNA ligase, cytoplasmic(Candida albicans)
Cubist Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50097093(7-Bromo-2-(4-bromo-phenyl)-8-methyl-quinoline-4-ca...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q23ZH8PubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50129528(2-[5-(2',4'-Dichloro-biphenyl-4-yl)-3-tetrazol-1-y...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibitory activity against Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7TCMPubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50265489((S)-2-(3-((S)-1-Carboxy-5-(naphthalen-1-ylmethylam...)copy SMILEScopy InChI
Affinity DataIC50: 154nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V987ZZPubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50143331((S)-1-{1-[2-(2,4-Dichloro-phenyl)-5-oxo-oxazol-(4Z...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4Q2FPubMed
TargetPhenylalanine--tRNA ligase, mitochondrial(Homo sapiens (Human))
Cubist Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50140728(13N-(3,4-dichlorophenyl)-2-hydroxy-11-oxo-14-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Compound was evaluated for the inhibitory activity against Escherichia coli phenylalanyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K073Q6PubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50143337((S)-1-{1-[2-(4-Bromo-phenyl)-5-oxo-oxazol-(4Z)-yli...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of human methionyl-tRNA synthetase (fMetRS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4Q2FPubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50143332((S)-1-{1-[2-(2,4-Dichloro-phenyl)-5-oxo-oxazol-(4Z...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4Q2FPubMed
TargetProline--tRNA ligase, cytoplasmic(Candida albicans)
Cubist Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50097104(6-Bromo-2-(4-bromo-phenyl)-8-trifluoromethyl-quino...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q23ZH8PubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50140707(5-(3-chloro-4-methylphenyl)-3-phenyl-(3R,3aS,6aR)-...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7VDSPubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50265391((S)-2-(3-((S)-1-Carboxy-5-(2-chlorobenzylamino)pen...)copy SMILEScopy InChI
Affinity DataIC50: 245nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V987ZZPubMed
TargetPhenylalanine--tRNA ligase, mitochondrial(Homo sapiens (Human))
Cubist Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50140728(13N-(3,4-dichlorophenyl)-2-hydroxy-11-oxo-14-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Compound was evaluated for the inhibitory activity against Staphylococcus aureus phenylalanyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K073Q6PubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50265451((S)-2-(3-((S)-1-Carboxy-5-(3-chlorobenzylamino)pen...)copy SMILEScopy InChI
Affinity DataIC50: 277nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V987ZZPubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50129551(CHEMBL74224 | {[5-(2',4'-Dichloro-biphenyl-4-yl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7TCMPubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50129534(5-(2',4'-Dichloro-biphenyl-4-yl)-1-pyridin-3-yl-1H...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against human methionyl-tRNA synthetase (hMetRS).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7TCMPubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50143343((S)-1-{1-[2-(2,4-Dichloro-phenyl)-5-oxo-oxazol-(4Z...)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Inhibition of human methionyl-tRNA synthetase (fMetRS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4Q2FPubMed
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