Compile Data Set for Download or QSAR
Found 27 with Last Name = 'lokwani' and Initial = 'd'
TargetAurora kinase A(Homo sapiens (Human))TBA
LigandPNGBDBM50004205(MK-045 | MK-0457 | TOZASERTIB | US9249124, VX680 |...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3XDTPubMed
TargetAurora kinase B(Homo sapiens (Human))TBA
LigandPNGBDBM50600442(CHEMBL5200042)copy SMILES
Affinity DataIC50: 12nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3XDTPubMed
TargetAurora kinase B(Homo sapiens (Human))TBA
LigandPNGBDBM50600441(CHEMBL5180210)copy SMILES
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3XDTPubMed
TargetAurora kinase A(Homo sapiens (Human))TBA
LigandPNGBDBM50600442(CHEMBL5200042)copy SMILES
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3XDTPubMed
TargetAurora kinase B(Homo sapiens (Human))TBA
LigandPNGBDBM50004205(MK-045 | MK-0457 | TOZASERTIB | US9249124, VX680 |...)copy SMILEScopy InChI
Affinity DataIC50: 19nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3XDTPubMed
TargetAurora kinase B(Homo sapiens (Human))TBA
LigandPNGBDBM50600443(CHEMBL5173220)copy SMILES
Affinity DataIC50: 22nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3XDTPubMed
TargetAurora kinase A(Homo sapiens (Human))TBA
LigandPNGBDBM50600441(CHEMBL5180210)copy SMILES
Affinity DataIC50: 33nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3XDTPubMed
TargetAurora kinase A(Homo sapiens (Human))TBA
LigandPNGBDBM50600443(CHEMBL5173220)copy SMILES
Affinity DataIC50: 42nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3XDTPubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies

Curated by ChEMBL
LigandPNGBDBM22984((8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-me...)copy SMILEScopy InChI
Affinity DataIC50: 940nMAssay Description:Inhibition of human DNA topoisomerase 2 catalytic activity using supercoiled pRYG DNA as substrate measured after 45 mins in presence of ATP by agaro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ07CRPubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies

Curated by ChEMBL
LigandPNGBDBM50543963(CHEMBL4636680)copy SMILEScopy InChI
Affinity DataIC50: 980nMAssay Description:Inhibition of human DNA topoisomerase 2 catalytic activity using supercoiled pRYG DNA as substrate measured after 45 mins in presence of ATP by agaro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ07CRPubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies

Curated by ChEMBL
LigandPNGBDBM22984((8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-me...)copy SMILEScopy InChI
Affinity DataIC50: 990nMAssay Description:Inhibition of human topoisomerase-2 alpha in human A498 cells assessed as decrease in relaxation of supercoiled DNA at 10 uMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ36GHPubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies

Curated by ChEMBL
LigandPNGBDBM50543962(CHEMBL4642846)copy SMILEScopy InChI
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of human DNA topoisomerase 2 catalytic activity using supercoiled pRYG DNA as substrate measured after 45 mins in presence of ATP by agaro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ07CRPubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
YB Chavan College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50485012(CHEMBL2022065)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase after 1 hr by colorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28918Q9PubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
YB Chavan College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50485014(CHEMBL2023097)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase after 1 hr by colorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28918Q9PubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
YB Chavan College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50485011(CHEMBL2022073)copy SMILEScopy InChI
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase after 1 hr by colorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28918Q9PubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
YB Chavan College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50485013(CHEMBL2023095)copy SMILEScopy InChI
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase after 1 hr by colorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28918Q9PubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies

Curated by ChEMBL
LigandPNGBDBM50543960(CHEMBL4633308)copy SMILEScopy InChI
Affinity DataIC50: 8.15E+3nMAssay Description:Inhibition of human DNA topoisomerase 2 catalytic activity using supercoiled pRYG DNA as substrate measured after 45 mins in presence of ATP by agaro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ07CRPubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies

Curated by ChEMBL
LigandPNGBDBM50570427(CHEMBL4864715)copy SMILES
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of human topoisomerase-2 alpha in human A498 cells assessed as decrease in relaxation of supercoiled DNA at 10 uMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ36GHPubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies

Curated by ChEMBL
LigandPNGBDBM50543961(CHEMBL4647427)copy SMILEScopy InChI
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of human DNA topoisomerase 2 catalytic activity using supercoiled pRYG DNA as substrate measured after 45 mins in presence of ATP by agaro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ07CRPubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies

Curated by ChEMBL
LigandPNGBDBM50570429(CHEMBL4878037)copy SMILES
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of human topoisomerase-2 alpha in human A498 cells assessed as decrease in relaxation of supercoiled DNA at 10 uMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ36GHPubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies

Curated by ChEMBL
LigandPNGBDBM50543958(CHEMBL4643603)copy SMILEScopy InChI
Affinity DataIC50: 1.55E+4nMAssay Description:Inhibition of human DNA topoisomerase 2 catalytic activity using supercoiled pRYG DNA as substrate measured after 45 mins in presence of ATP by agaro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ07CRPubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies

Curated by ChEMBL
LigandPNGBDBM50570428(CHEMBL4870551)copy SMILES
Affinity DataIC50: 1.67E+4nMAssay Description:Inhibition of human topoisomerase-2 alpha in human A498 cells assessed as decrease in relaxation of supercoiled DNA at 10 uMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ36GHPubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies

Curated by ChEMBL
LigandPNGBDBM50570432(CHEMBL4849502)copy SMILES
Affinity DataIC50: 1.71E+4nMAssay Description:Inhibition of human topoisomerase-2 alpha in human A498 cells assessed as decrease in relaxation of supercoiled DNA at 10 uMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ36GHPubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies

Curated by ChEMBL
LigandPNGBDBM50543959(CHEMBL4636706)copy SMILEScopy InChI
Affinity DataIC50: 2.08E+4nMAssay Description:Inhibition of human DNA topoisomerase 2 catalytic activity using supercoiled pRYG DNA as substrate measured after 45 mins in presence of ATP by agaro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ07CRPubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies

Curated by ChEMBL
LigandPNGBDBM50570430(CHEMBL4855587)copy SMILES
Affinity DataIC50: 2.64E+4nMAssay Description:Inhibition of human topoisomerase-2 alpha in human A498 cells assessed as decrease in relaxation of supercoiled DNA at 10 uMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ36GHPubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies

Curated by ChEMBL
LigandPNGBDBM50570431(CHEMBL4869150)copy SMILES
Affinity DataIC50: 3.99E+4nMAssay Description:Inhibition of human topoisomerase-2 alpha in human A498 cells assessed as decrease in relaxation of supercoiled DNA at 10 uMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ36GHPubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies

Curated by ChEMBL
LigandPNGBDBM50570433(CHEMBL4853443)copy SMILES
Affinity DataIC50: 4.84E+4nMAssay Description:Inhibition of human topoisomerase-2 alpha in human A498 cells assessed as decrease in relaxation of supercoiled DNA at 10 uMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ36GHPubMed