Found 74 with Last Name = 'mahuran' and Initial = 'd' 
Affinity DataKi: 0.0700nMpH: 7.0Assay Description:Fluorescene-based assay using beta-glucocerebrosidase.More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMpH: 5.5Assay Description:Fluorescene-based assay using beta-glucocerebrosidase.More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 4-methylumbelliferyl beta-D-glucopyranoside as substrate after 15 mins by Dixon an...More data for this Ligand-Target Pair
Affinity DataKi: 1.80nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 4-methylumbelliferyl beta-D-glucopyranoside as substrate after 15 mins by Dixon an...More data for this Ligand-Target Pair
Affinity DataKi: 3nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 4-methylumbelliferyl beta-D-glucopyranoside as substrate after 15 mins by Dixon an...More data for this Ligand-Target Pair
Affinity DataKi: 4nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 4-methylumbelliferyl beta-D-glucopyranoside as substrate after 15 mins by Dixon an...More data for this Ligand-Target Pair
Affinity DataKi: 4.40nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 4-methylumbelliferyl beta-D-glucopyranoside as substrate after 15 mins by Dixon an...More data for this Ligand-Target Pair
Affinity DataKi: 5nMpH: 7.0Assay Description:Fluorescene-based assay using beta-glucocerebrosidase.More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKi: 6nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 4-methylumbelliferyl beta-D-glucopyranoside as substrate after 15 mins by Dixon an...More data for this Ligand-Target Pair
Affinity DataKi: 12nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 4-methylumbelliferyl beta-D-glucopyranoside as substrate after 15 mins by Dixon an...More data for this Ligand-Target Pair
Affinity DataKi: 18nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 4-methylumbelliferyl beta-D-glucopyranoside as substrate after 15 mins by Dixon an...More data for this Ligand-Target Pair
Affinity DataKi: 19nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 4-methylumbelliferyl beta-D-glucopyranoside as substrate after 15 mins by Dixon an...More data for this Ligand-Target Pair
Affinity DataKi: 23nMpH: 5.5Assay Description:Fluorescene-based assay using beta-glucocerebrosidase.More data for this Ligand-Target Pair
Affinity DataKi: 29nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 2,4-dinitrophenyl beta-D-glucopyranoside as substrate after 3 mins by Dixon and Li...More data for this Ligand-Target Pair
Affinity DataKi: 30nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 2,4-dinitrophenyl beta-D-glucopyranoside as substrate after 3 mins by Dixon and Li...More data for this Ligand-Target Pair
Affinity DataKi: 76nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 2,4-dinitrophenyl beta-D-glucopyranoside as substrate after 3 mins by Dixon and Li...More data for this Ligand-Target Pair
Affinity DataKi: 100nMpH: 5.5Assay Description:Fluorescene-based assay using beta-glucocerebrosidase.More data for this Ligand-Target Pair
Affinity DataKi: 110nMpH: 7.0Assay Description:Fluorescene-based assay using beta-glucocerebrosidase.More data for this Ligand-Target Pair
Affinity DataKi: 180nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 2,4-dinitrophenyl beta-D-glucopyranoside as substrate after 3 mins by Dixon and Li...More data for this Ligand-Target Pair
Affinity DataKi: 200nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 2,4-dinitrophenyl beta-D-glucopyranoside as substrate after 3 mins by Dixon and Li...More data for this Ligand-Target Pair
Affinity DataKi: 210nMpH: 7.0Assay Description:Fluorescene-based assay using beta-glucocerebrosidase.More data for this Ligand-Target Pair
Affinity DataKi: 250nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 2,4-dinitrophenyl beta-D-glucopyranoside as substrate after 3 mins by Dixon and Li...More data for this Ligand-Target Pair
Affinity DataKi: 450nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 2,4-dinitrophenyl beta-D-glucopyranoside as substrate after 3 mins by Dixon and Li...More data for this Ligand-Target Pair
Affinity DataKi: 600nMpH: 5.5Assay Description:Fluorescene-based assay using beta-glucocerebrosidase.More data for this Ligand-Target Pair
Affinity DataKi: 610nMpH: 5.5Assay Description:Fluorescene-based assay using beta-glucocerebrosidase.More data for this Ligand-Target Pair
Affinity DataKi: 1.10E+3nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 2,4-dinitrophenyl beta-D-glucopyranoside as substrate after 3 mins by Dixon and Li...More data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMpH: 7.0Assay Description:Fluorescene-based assay using beta-glucocerebrosidase.More data for this Ligand-Target Pair
Affinity DataKi: 2.70E+3nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 2,4-dinitrophenyl beta-D-glucopyranoside as substrate after 3 mins by Dixon and Li...More data for this Ligand-Target Pair
Affinity DataKi: 2.80E+3nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 2,4-dinitrophenyl beta-D-glucopyranoside as substrate after 3 mins by Dixon and Li...More data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Research Institute, Hospital for Sick Children
Research Institute, Hospital for Sick Children
Affinity DataIC50: 600nMT: 2°CAssay Description:Enzyme assay based on 4-MU substrates with HTS to identify inhibitory compounds for Hex.More data for this Ligand-Target Pair
TargetCytosolic beta-glucosidase(Homo sapiens (Human))
University of British Columbia
Curated by ChEMBL
University of British Columbia
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human cytosolic beta-glucosidase using 4-methylumbelliferyl beta-D-glucopyranoside as substrate after 15 mins by fluorimetric analysisMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Research Institute, Hospital for Sick Children
Research Institute, Hospital for Sick Children
Affinity DataIC50: 3.10E+3nMpH: 7.0Assay Description:Inhibition of human placental HexA using MUGS substrate incubated for 1 to 2 hrs at pH 7.0 by spectrofluorometryMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit beta(Homo sapiens (Human))
Genetics and Genome Biology, SickKids, PGCRL 686 Bay Street, Toronto, Ontario M5G 0A4, Canada.
Curated by ChEMBL
Genetics and Genome Biology, SickKids, PGCRL 686 Bay Street, Toronto, Ontario M5G 0A4, Canada.
Curated by ChEMBL
Affinity DataIC50: 4.50E+3nMpH: 7.0Assay Description:Inhibition of human placental HexB using MUGS substrate incubated for 1 to 2 hrs at pH 7.0 by spectrofluorometryMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Research Institute, Hospital for Sick Children
Research Institute, Hospital for Sick Children
Affinity DataIC50: 4.60E+3nMT: 2°CAssay Description:Enzyme assay based on 4-MU substrates with HTS to identify inhibitory compounds for Hex.More data for this Ligand-Target Pair
Affinity DataIC50: 4.70E+3nMpH: 5.5 T: 2°CAssay Description:Beta-glucocerebrosidase (GCase) activity was measured by release of 4-methylumbelliferyl fluorophore from MUClc.More data for this Ligand-Target Pair
Affinity DataIC50: 7.80E+3nMpH: 5.5 T: 2°CAssay Description:Beta-glucocerebrosidase (GCase) activity was measured by release of 4-methylumbelliferyl fluorophore from MUClc.More data for this Ligand-Target Pair
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of human lysosomal beta galactosidaseMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Research Institute, Hospital for Sick Children
Research Institute, Hospital for Sick Children
Affinity DataIC50: 8.50E+3nMpH: 4.5Assay Description:Inhibition of HexA alpha G269S mutant in ATSD patient fibroblasts using MUGS substrate incubated for 1 to 2 hrs at pH 4.5 by spectrofluorometryMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Research Institute, Hospital for Sick Children
Research Institute, Hospital for Sick Children
Affinity DataIC50: 8.90E+3nMpH: 4.5Assay Description:Inhibition of human placental HexA using MUGS substrate incubated for 1 to 2 hrs at pH 4.5 by spectrofluorometryMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit beta(Homo sapiens (Human))
Genetics and Genome Biology, SickKids, PGCRL 686 Bay Street, Toronto, Ontario M5G 0A4, Canada.
Curated by ChEMBL
Genetics and Genome Biology, SickKids, PGCRL 686 Bay Street, Toronto, Ontario M5G 0A4, Canada.
Curated by ChEMBL
Affinity DataIC50: 9.10E+3nMpH: 4.5Assay Description:Inhibition of human placental HexB using MUGS substrate incubated for 1 to 2 hrs at pH 4.5 by spectrofluorometryMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Research Institute, Hospital for Sick Children
Research Institute, Hospital for Sick Children
Affinity DataIC50: 1.10E+4nMpH: 7.0Assay Description:Inhibition of human placental HexA using MUGS substrate incubated for 1 to 2 hrs at pH 7.0 by spectrofluorometryMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Research Institute, Hospital for Sick Children
Research Institute, Hospital for Sick Children
Affinity DataIC50: 1.40E+4nMpH: 4.5Assay Description:Inhibition of HexA in normal human fibroblasts using MUGS substrate incubated for 1 to 2 hrs at pH 4.5 by spectrofluorometryMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit beta(Homo sapiens (Human))
Genetics and Genome Biology, SickKids, PGCRL 686 Bay Street, Toronto, Ontario M5G 0A4, Canada.
Curated by ChEMBL
Genetics and Genome Biology, SickKids, PGCRL 686 Bay Street, Toronto, Ontario M5G 0A4, Canada.
Curated by ChEMBL
Affinity DataIC50: 1.50E+4nMpH: 7.0Assay Description:Inhibition of human placental HexB using MUGS substrate incubated for 1 to 2 hrs at pH 7.0 by spectrofluorometryMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Research Institute, Hospital for Sick Children
Research Institute, Hospital for Sick Children
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human placental HexA using pNPGlcNAc substrateMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha/beta(Homo sapiens (Human))
Genetics and Genome Biology, SickKids, PGCRL 686 Bay Street, Toronto, Ontario M5G 0A4, Canada.
Curated by ChEMBL
Genetics and Genome Biology, SickKids, PGCRL 686 Bay Street, Toronto, Ontario M5G 0A4, Canada.
Curated by ChEMBL
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of beta-N-acetylhexosaminidase (unknown origin)More data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Research Institute, Hospital for Sick Children
Research Institute, Hospital for Sick Children
Affinity DataIC50: 1.60E+4nMT: 2°CAssay Description:Enzyme assay based on 4-MU substrates with HTS to identify inhibitory compounds for Hex.More data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Research Institute, Hospital for Sick Children
Research Institute, Hospital for Sick Children
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human placental HexA using pNPGlcNAc substrateMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Research Institute, Hospital for Sick Children
Research Institute, Hospital for Sick Children
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human placental HexA using pNPGlcNAc substrateMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Research Institute, Hospital for Sick Children
Research Institute, Hospital for Sick Children
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human placental HexA using pNPGlcNAc substrateMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Research Institute, Hospital for Sick Children
Research Institute, Hospital for Sick Children
Affinity DataIC50: 1.80E+4nMT: 2°CAssay Description:Enzyme assay based on 4-MU substrates with HTS to identify inhibitory compounds for Hex.More data for this Ligand-Target Pair
