Compile Data Set for Download or QSAR
Found 267 with Last Name = 'mccann' and Initial = 'd'
TargetEstrogen receptor(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212159(2-(4-isopropylphenyl)-3-(4-(2-(piperidin-1-yl)etho...)copy SMILEScopy InChI
Affinity DataKi:  0.0910nMAssay Description:Displacement of [3H]estradiol from human recombinant ERalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2W6FPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212148(6-(3-fluorophenyl)-5-(4-(2-(piperidin-1-yl)ethoxy)...)copy SMILEScopy InChI
Affinity DataKi:  0.160nMAssay Description:Displacement of [3H]estradiol from human recombinant ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2W6FPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212148(6-(3-fluorophenyl)-5-(4-(2-(piperidin-1-yl)ethoxy)...)copy SMILEScopy InChI
Affinity DataKi:  0.180nMAssay Description:Displacement of [3H]estradiol from human recombinant ERalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2W6FPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19964(6-(4-hydroxyphenyl)-5-({4-[2-(piperidin-1-yl)ethox...)copy SMILEScopy InChI
Affinity DataKi:  0.200nM ΔG°:  -54.8kJ/mole EC50:  1.14nMpH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR1WHWPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212157(6-(3,4-difluorophenyl)-5-(4-(2-(piperidin-1-yl)eth...)copy SMILEScopy InChI
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]estradiol from human recombinant ERalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2W6FPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212149(6-(3-hydroxyphenyl)-5-(4-(2-(piperidin-1-yl)ethoxy...)copy SMILEScopy InChI
Affinity DataKi:  0.210nMAssay Description:Displacement of [3H]estradiol from human recombinant ERalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2W6FPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19967(6-(4-fluorophenyl)-5-{4-[2-(piperidin-1-yl)ethoxy]...)copy SMILEScopy InChI
Affinity DataKi:  0.240nMAssay Description:Displacement of [3H]estradiol from human recombinant ERalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2W6FPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212160(3-(6-hydroxy-1-(4-(2-(piperidin-1-yl)ethoxy)phenox...)copy SMILEScopy InChI
Affinity DataKi:  0.240nMAssay Description:Displacement of [3H]estradiol from human recombinant ERalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2W6FPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19967(6-(4-fluorophenyl)-5-{4-[2-(piperidin-1-yl)ethoxy]...)copy SMILEScopy InChI
Affinity DataKi:  0.25nM ΔG°:  -54.3kJ/mole EC50:  3.18nMpH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR1WHWPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19967(6-(4-fluorophenyl)-5-{4-[2-(piperidin-1-yl)ethoxy]...)copy SMILEScopy InChI
Affinity DataKi:  0.280nMAssay Description:Displacement of [3H]estradiol from human recombinant ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2W6FPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212157(6-(3,4-difluorophenyl)-5-(4-(2-(piperidin-1-yl)eth...)copy SMILEScopy InChI
Affinity DataKi:  0.290nMAssay Description:Displacement of [3H]estradiol from human recombinant ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2W6FPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19967(6-(4-fluorophenyl)-5-{4-[2-(piperidin-1-yl)ethoxy]...)copy SMILEScopy InChI
Affinity DataKi:  0.300nM ΔG°:  -53.8kJ/mole EC50:  3.18nMpH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR1WHWPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212147(6-(4-hydroxyphenyl)-5-(4-(2-(piperidin-1-yl)ethoxy...)copy SMILEScopy InChI
Affinity DataKi:  0.320nMAssay Description:Displacement of [3H]estradiol from human recombinant ERalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2W6FPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212160(3-(6-hydroxy-1-(4-(2-(piperidin-1-yl)ethoxy)phenox...)copy SMILEScopy InChI
Affinity DataKi:  0.350nMAssay Description:Displacement of [3H]estradiol from human recombinant ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2W6FPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212149(6-(3-hydroxyphenyl)-5-(4-(2-(piperidin-1-yl)ethoxy...)copy SMILEScopy InChI
Affinity DataKi:  0.360nMAssay Description:Displacement of [3H]estradiol from human recombinant ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2W6FPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19441(2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethox...)copy SMILEScopy InChI
Affinity DataKi:  0.370nM ΔG°:  -53.3kJ/mole EC50:  4.32nMpH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212153(4-(6-hydroxy-1-(4-(2-(piperidin-1-yl)ethoxy)phenox...)copy SMILEScopy InChI
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]estradiol from human recombinant ERalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2W6FPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19966(6-(4-methanesulfonylphenyl)-5-{4-[2-(piperidin-1-y...)copy SMILEScopy InChI
Affinity DataKi:  0.470nMAssay Description:Displacement of [3H]estradiol from human recombinant ERalphaMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212147(6-(4-hydroxyphenyl)-5-(4-(2-(piperidin-1-yl)ethoxy...)copy SMILEScopy InChI
Affinity DataKi:  0.480nMAssay Description:Displacement of [3H]estradiol from human recombinant ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2W6FPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212155(2-(4-(ethylsulfonyl)phenyl)-3-(4-(2-(piperidin-1-y...)copy SMILEScopy InChI
Affinity DataKi:  0.480nMAssay Description:Displacement of [3H]estradiol from human recombinant ERalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2W6FPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19966(6-(4-methanesulfonylphenyl)-5-{4-[2-(piperidin-1-y...)copy SMILEScopy InChI
Affinity DataKi:  0.510nM ΔG°:  -52.5kJ/mole EC50:  10.7nMpH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212158(4-(6-hydroxy-1-(4-(2-(piperidin-1-yl)ethoxy)phenox...)copy SMILEScopy InChI
Affinity DataKi:  0.570nMAssay Description:Displacement of [3H]estradiol from human recombinant ERalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2W6FPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212159(2-(4-isopropylphenyl)-3-(4-(2-(piperidin-1-yl)etho...)copy SMILEScopy InChI
Affinity DataKi:  0.630nMAssay Description:Displacement of [3H]estradiol from human recombinant ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2W6FPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19447(2-(4-methanesulfonylphenyl)-3-{4-[2-(piperidin-1-y...)copy SMILEScopy InChI
Affinity DataKi:  0.630nMAssay Description:Displacement of [3H]estradiol from human recombinant ERalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2W6FPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19964(6-(4-hydroxyphenyl)-5-({4-[2-(piperidin-1-yl)ethox...)copy SMILEScopy InChI
Affinity DataKi:  0.700nM ΔG°:  -51.7kJ/mole EC50:  1.14nMpH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR1WHWPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212150(6-(4-(isopropylsulfonyl)phenyl)-5-(4-(2-(piperidin...)copy SMILEScopy InChI
Affinity DataKi:  0.730nMAssay Description:Displacement of [3H]estradiol from human recombinant ERalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2W6FPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212152(6-(1,1-dioxo-1,2,3,6-tetrahydro-1lambda*6*-thiopyr...)copy SMILEScopy InChI
Affinity DataKi:  1.03nMAssay Description:Displacement of [3H]estradiol from human recombinant ERalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2W6FPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212151(6-(4-(methylsulfonyl)cyclohex-1-enyl)-5-(4-(2-(pip...)copy SMILEScopy InChI
Affinity DataKi:  1.09nMAssay Description:Displacement of [3H]estradiol from human recombinant ERalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2W6FPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19965(6-(4-methanesulfonylphenyl)-5-({4-[2-(piperidin-1-...)copy SMILEScopy InChI
Affinity DataKi:  1.15nM ΔG°:  -50.5kJ/mole EC50:  4.78nMpH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR1WHWPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212158(4-(6-hydroxy-1-(4-(2-(piperidin-1-yl)ethoxy)phenox...)copy SMILEScopy InChI
Affinity DataKi:  1.16nMAssay Description:Displacement of [3H]estradiol from human recombinant ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2W6FPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212156(6-(4-(ethylsulfonyl)phenyl)-5-(4-(2-(piperidin-1-y...)copy SMILEScopy InChI
Affinity DataKi:  1.22nMAssay Description:Displacement of [3H]estradiol from human recombinant ERalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2W6FPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19966(6-(4-methanesulfonylphenyl)-5-{4-[2-(piperidin-1-y...)copy SMILEScopy InChI
Affinity DataKi:  1.32nMAssay Description:Displacement of [3H]estradiol from human recombinant ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2W6FPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19966(6-(4-methanesulfonylphenyl)-5-{4-[2-(piperidin-1-y...)copy SMILEScopy InChI
Affinity DataKi:  1.36nM ΔG°:  -50.1kJ/mole EC50:  10.7nMpH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR1WHWPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212153(4-(6-hydroxy-1-(4-(2-(piperidin-1-yl)ethoxy)phenox...)copy SMILEScopy InChI
Affinity DataKi:  1.69nMAssay Description:Displacement of [3H]estradiol from human recombinant ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2W6FPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212154(6-(1,1-dioxo-hexahydro-1lambda*6*-thiopyran-4-yl)-...)copy SMILEScopy InChI
Affinity DataKi:  1.89nMAssay Description:Displacement of [3H]estradiol from human recombinant ERalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2W6FPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212152(6-(1,1-dioxo-1,2,3,6-tetrahydro-1lambda*6*-thiopyr...)copy SMILEScopy InChI
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]estradiol from human recombinant ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2W6FPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212150(6-(4-(isopropylsulfonyl)phenyl)-5-(4-(2-(piperidin...)copy SMILEScopy InChI
Affinity DataKi:  2.17nMAssay Description:Displacement of [3H]estradiol from human recombinant ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2W6FPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212151(6-(4-(methylsulfonyl)cyclohex-1-enyl)-5-(4-(2-(pip...)copy SMILEScopy InChI
Affinity DataKi:  2.69nMAssay Description:Displacement of [3H]estradiol from human recombinant ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2W6FPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19441(2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethox...)copy SMILEScopy InChI
Affinity DataKi:  2.74nM ΔG°:  -48.4kJ/mole EC50:  4.32nMpH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212154(6-(1,1-dioxo-hexahydro-1lambda*6*-thiopyran-4-yl)-...)copy SMILEScopy InChI
Affinity DataKi:  4.11nMAssay Description:Displacement of [3H]estradiol from human recombinant ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2W6FPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212156(6-(4-(ethylsulfonyl)phenyl)-5-(4-(2-(piperidin-1-y...)copy SMILEScopy InChI
Affinity DataKi:  4.19nMAssay Description:Displacement of [3H]estradiol from human recombinant ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2W6FPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19447(2-(4-methanesulfonylphenyl)-3-{4-[2-(piperidin-1-y...)copy SMILEScopy InChI
Affinity DataKi:  13.6nMAssay Description:Displacement of [3H]estradiol from human recombinant ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2W6FPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212155(2-(4-(ethylsulfonyl)phenyl)-3-(4-(2-(piperidin-1-y...)copy SMILEScopy InChI
Affinity DataKi:  15.7nMAssay Description:Displacement of [3H]estradiol from human recombinant ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2W6FPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19965(6-(4-methanesulfonylphenyl)-5-({4-[2-(piperidin-1-...)copy SMILEScopy InChI
Affinity DataKi:  24.1nM ΔG°:  -43.0kJ/mole EC50:  4.78nMpH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR1WHWPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Eli Lilly and Company

Curated by ChEMBL
LigandPNGBDBM50096333(CHEMBL3577114)copy SMILEScopy InChI
Affinity DataIC50: 0.460nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2Z85PubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50150699(3-(9-fluoro-2-(piperidine-1-carbonyl)-1,2,3,4-tetr...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of GSK3beta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8NS4PubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Eli Lilly and Company

Curated by ChEMBL
LigandPNGBDBM50096333(CHEMBL3577114)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant BRAF V600E mutant (unknown origin) assessed as ADP formation measured for 5 hrs by pyruvate kinase/lactate dehydrogenase co...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2Z85PubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Eli Lilly and Company

Curated by ChEMBL
LigandPNGBDBM50096332(CHEMBL3577115)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of recombinant BRAF V600E mutant (unknown origin) assessed as ADP formation measured for 5 hrs by pyruvate kinase/lactate dehydrogenase co...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2Z85PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Eli Lilly and Company

Curated by ChEMBL
LigandPNGBDBM50096323(CHEMBL3577123)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of wild type CRAF (unknown origin) assessed as ADP formation measured for 5 hrs by pyruvate kinase/lactate dehydrogenase coupled assay in ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2Z85PubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50150699(3-(9-fluoro-2-(piperidine-1-carbonyl)-1,2,3,4-tetr...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of GSK3alpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8NS4PubMed
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