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Found 295 with Last Name = 'steadman' and Initial = 'd'
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50144578(CHEMBL3760062)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NP28F9PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539233(CHEMBL4642625)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50154397(CHEMBL3774760)copy SMILEScopy InChI
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539213(CHEMBL4637176)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50154397(CHEMBL3774760)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50154397(CHEMBL3774760)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of C-terminal His-tagged Notum (Ser81-Thr451 Cys330Ser) (unknown origin) using OPTS as substrate by fluorescence based assayMore data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539211(CHEMBL4642915)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539244(CHEMBL4648963)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539246(CHEMBL4632439)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50154387(CHEMBL3774528)copy SMILEScopy InChI
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NP28F9PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539220(CHEMBL4646043)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539221(CHEMBL4637948)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539212(CHEMBL4648770)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50154387(CHEMBL3774528)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539214(CHEMBL4641132)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539243(CHEMBL4637227)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539222(CHEMBL4643862)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539234(CHEMBL4641550)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539248(CHEMBL4633059)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539223(CHEMBL4634865)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50583122(CHEMBL5078659)copy SMILES
Affinity DataIC50: 4nMAssay Description:Inhibition of human Notum (81 to 451 Cys330Ser) using OPTS as substrate incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539216(CHEMBL4636343)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50583131(CHEMBL5070478)copy SMILES
Affinity DataIC50: 5nMAssay Description:Inhibition of human Notum (81 to 451 Cys330Ser) using OPTS as substrate incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50154370(CHEMBL1689356)copy SMILEScopy InChI
Affinity DataIC50: 5.80nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539210(CHEMBL4641545)copy SMILEScopy InChI
Affinity DataIC50: 5.80nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50583112(CHEMBL5079105)copy SMILES
Affinity DataIC50: 6nMAssay Description:Inhibition of human Notum (81 to 451 Cys330Ser) using OPTS as substrate incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539215(CHEMBL4647057)copy SMILEScopy InChI
Affinity DataIC50: 6.20nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM601033(1-[2,4-dichloro-3-(trifluoromethyl)phenyl]triazole...)copy SMILES
Affinity DataIC50: 6.5nMMore data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50583127(CHEMBL5077097)copy SMILES
Affinity DataIC50: 7nMAssay Description:Inhibition of human Notum (81 to 451 Cys330Ser) using OPTS as substrate incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ43T1PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539247(CHEMBL4636894)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539209(CHEMBL4640648)copy SMILEScopy InChI
Affinity DataIC50: 7.10nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539203(CHEMBL4646342)copy SMILEScopy InChI
Affinity DataIC50: 7.5nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))TBA
LigandPNGBDBM50589392(Adavivint | LORECIVIVINT | Lorecivivint | SM-04690...)copy SMILES
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NP28F9PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539236(CHEMBL4632898)copy SMILEScopy InChI
Affinity DataIC50: 8.10nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50583101(CHEMBL5088670)copy SMILES
Affinity DataIC50: 8.5nMAssay Description:Inhibition of human Notum (81 to 451 Cys330Ser) using OPTS as substrate incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ43T1PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50583109(CHEMBL5076852)copy SMILES
Affinity DataIC50: 9nMAssay Description:Inhibition of human Notum (81 to 451 Cys330Ser) using OPTS as substrate incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539245(CHEMBL4632460)copy SMILEScopy InChI
Affinity DataIC50: 9.40nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539229(CHEMBL4636249)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50579725(CHEMBL5072324)copy SMILES
Affinity DataIC50: 12nMAssay Description:Covalent inhibition of glycosylated Notum 1 (unknown origin) using OPTS as reporter substrate incubated for 40 mins by microplate reader based analys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50583097(CHEMBL5078105)copy SMILES
Affinity DataIC50: 12nMAssay Description:Inhibition of human Notum (81 to 451 Cys330Ser) using OPTS as substrate incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ43T1PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50583129(CHEMBL5087217)copy SMILES
Affinity DataIC50: 13nMAssay Description:Inhibition of human Notum (81 to 451 Cys330Ser) using OPTS as substrate incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ43T1PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50583105(CHEMBL5093578)copy SMILES
Affinity DataIC50: 14nMAssay Description:Inhibition of human Notum (81 to 451 Cys330Ser) using OPTS as substrate incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ43T1PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50583125(CHEMBL5092159)copy SMILES
Affinity DataIC50: 14nMAssay Description:Inhibition of human Notum (81 to 451 Cys330Ser) using OPTS as substrate incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ43T1PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50583120(CHEMBL5085330)copy SMILES
Affinity DataIC50: 15nMAssay Description:Inhibition of human Notum (81 to 451 Cys330Ser) using OPTS as substrate incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ43T1PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539204(CHEMBL4649597)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539228(CHEMBL4642569)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539224(CHEMBL4634165)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50583106(CHEMBL5079572)copy SMILES
Affinity DataIC50: 17nMAssay Description:Inhibition of human Notum (81 to 451 Cys330Ser) using OPTS as substrate incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ43T1PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50583118(CHEMBL5088818)copy SMILES
Affinity DataIC50: 17nMAssay Description:Inhibition of human Notum (81 to 451 Cys330Ser) using OPTS as substrate incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ43T1PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539230(CHEMBL4643464)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
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